Persistent diffuse lymphadenopathy in homosexual men: endpoint or prodrome?

abstract：BACKGROUND:National guidelines recommend that physicians discuss end-of-life (EOL) care planning with patients with cancer whose life expectancy is less than 1 year. OBJECTIVE:To evaluate the incidence of EOL care discussions for patients with stage IV lung or colorectal cancer and where, when, and with whom these dis...

journal_title：Annals of internal medicine

authors： Mack JW,Cronin A,Taback N,Huskamp HA,Keating NL,Malin JL,Earle CC,Weeks JC

更新日期：2012-02-07 00:00:00

abstract：:Wilson's disease is an inherited disorder of copper accumulation that is fatal if untreated. Because penicillamine, the established treatment, is toxic in a substantial number of patients, we studied the efficacy of zinc treatment. We induced a negative or neutral copper balance in five out of five patients with Wilso...

journal_title：Annals of internal medicine

authors： Brewer GJ,Hill GM,Prasad AS,Cossack ZT,Rabbani P

更新日期：1983-09-01 00:00:00

abstract：STUDY OBJECTIVE:To assess the effect of weight-bearing exercise training and subsequent detraining on lumbar bone mineral content in postmenopausal women. DESIGN:Non-randomized, controlled, short-term (9 months) trial and long-term (22 months) exercise training and detraining (13 months). SETTING:Section of applied p...

journal_title：Annals of internal medicine

authors： Dalsky GP,Stocke KS,Ehsani AA,Slatopolsky E,Lee WC,Birge SJ Jr

更新日期：1988-06-01 00:00:00

abstract：:Research on assessing or managing medication adherence applies approaches from observational, interventional, and implementation science that spans many disciplines and demands coherent conceptualization, valid methods, appropriate analyses, and complete and accurate reporting. To ensure such reporting, the European S...

journal_title：Annals of internal medicine

authors： De Geest S,Zullig LL,Dunbar-Jacob J,Helmy R,Hughes DA,Wilson IB,Vrijens B

更新日期：2018-07-03 00:00:00

abstract：OBJECTIVE:To provide a rational strategy for the evaluation and long-term management of epilepsy. DATA SOURCES:Articles written between 1964 and 1993, obtained from a MEDLINE search on epilepsy-related topics as well as from the author's personal files, major reference books on antiepileptic drugs, and references iden...

journal_title：Annals of internal medicine

authors： French J

更新日期：1994-03-01 00:00:00

abstract：:In an era of increasing competition in medical care, critical pathway guidelines have emerged as one of the most popular new initiatives intended to reduce costs while maintaining or even improving the quality of care. Developed primarily for high-volume hospital diagnoses, critical pathways display goals for patients...

journal_title：Annals of internal medicine

authors： Pearson SD,Goulart-Fisher D,Lee TH

更新日期：1995-12-15 00:00:00

abstract：Background:Stroke rates in patients with nonvalvular atrial fibrillation (AF) who are not receiving anticoagulant therapy vary widely across published studies; the resulting effect on the net clinical benefit of anticoagulation in AF is unknown. Objective:To determine the effect of variation in published AF stroke rat...

journal_title：Annals of internal medicine

authors： Shah SJ,Eckman MH,Aspberg S,Go AS,Singer DE

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is a common cause of serious infection in patients infected with HIV. OBJECTIVES:To evaluate risk factors for and quantitative effect of S. aureus infection in HIV-infected patients, with special attention to nasal carriage. DESIGN:Prospective, multihospital cohort study. SETTING:Thr...

journal_title：Annals of internal medicine

authors： Nguyen MH,Kauffman CA,Goodman RP,Squier C,Arbeit RD,Singh N,Wagener MM,Yu VL

更新日期：1999-02-02 00:00:00

abstract：:This paper is part 1 of a 2-part series on interpretation of 12-lead resting electrocardiograms (ECGs). Part 1 is a position paper that presents recommendations for initial competency, competency assessment, and maintenance of competency on ECG interpretation, as well as recommendations for the role of computer-assist...

journal_title：Annals of internal medicine

authors： Salerno SM,Alguire PC,Waxman HS,American College of Physicians.

更新日期：2003-05-06 00:00:00

abstract：:Disseminated candidiasis has become an important infection, particularly in immunocompromised and postoperative patients. Although serologic tests may, in some settings, facilitate a premortem diagnosis, the disease is usually diagnosed by comprehensive clinical evaluation. Detection of the relatively newly recognized...

journal_title：Annals of internal medicine

authors： Edwards JE Jr,Lehrer RI,Stiehm ER,Fischer TJ,Young LS

更新日期：1978-07-01 00:00:00

abstract：:Since 1970, forty-two patients with pulmonary hypertension due to chronic, thromboembolic obstruction of the major pulmonary arteries have had pulmonary thromboendarterectomy at the University of California, San Diego, and the San Diego Veterans Medical Centers. Duration of symptoms before admission averaged 4.4 years...

journal_title：Annals of internal medicine

authors： Moser KM,Daily PO,Peterson K,Dembitsky W,Vapnek JM,Shure D,Utley J,Archibald C

更新日期：1987-10-01 00:00:00

abstract：:Young adults with cystic fibrosis have lower blood pressures than control subjects of similar age and sex. The low blood pressure may be related to the excessive loss of salt in the sweat of these patients. A beneficial effect of the cystic fibrosis gene may be protection against developing hypertension in both the ho...

journal_title：Annals of internal medicine

authors： Lieberman J,Rodbard S

更新日期：1975-06-01 00:00:00

abstract：:Five of 70 patients with systemic lupus erythematosus seen over a 5-year period had peripheral blood films suggestive of hyposplenism. Technetium-99m-sulfur colloid scans showed no splenic activity in three patients. One of these three patients, who had a spontaneous remission of persistent thrombocytopenia concurrent...

journal_title：Annals of internal medicine

authors： Dillon AM,Stein HB,English RA

更新日期：1982-01-01 00:00:00

abstract：:We describe a sporadic, vitamin-D-resistant osteomalacic syndrome in 19 patients undergoing hemodialysis. The syndrome was found in less than 1.5% of patients from referring dialysis centers. All 19 patients had multiple fractures, severe myopathy, and many developed spontaneous hypercalcemia. Severe osteomalacia with...

journal_title：Annals of internal medicine

authors： Hodsman AB,Sherrard DJ,Wong EG,Brickman AS,Lee DB,Alfrey AC,Singer FR,Norman AW,Coburn JW

更新日期：1981-05-01 00:00:00

abstract：DESCRIPTION:New recommendation from the U.S. Preventive Services Task Force (USPSTF) on the use of nontraditional, or novel, risk factors in assessing the coronary heart disease (CHD) risk of asymptomatic persons. METHODS:Systematic reviews were conducted of literature since 1996 on 9 proposed nontraditional markers o...

journal_title：Annals of internal medicine

authors： U.S. Preventive Services Task Force.

更新日期：2009-10-06 00:00:00

abstract：:A group of 44 homosexual patients with immune thrombocytopenia and serologic evidence of infection with the human immunodeficiency virus (HIV) was observed for a total of 844 person-months. The risk of developing the acquired immunodeficiency syndrome (AIDS), an actuarial incidence of 36.5% in 37 months, was no differ...

journal_title：Annals of internal medicine

authors： Holzman RS,Walsh CM,Karpatkin S

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Combining endoscopic therapy and beta-blockers may improve outcomes in patients with cirrhosis and bleeding esophageal varices. PURPOSE:To assess whether a combination of endoscopic and drug therapy prevents overall and variceal rebleeding and improves survival better than either therapy alone. DATA SOURCE...

journal_title：Annals of internal medicine

authors： Gonzalez R,Zamora J,Gomez-Camarero J,Molinero LM,Bañares R,Albillos A

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:Depressive disorders are persistent, recurring illnesses that cause great suffering for patients and their families. PURPOSE:To evaluate the benefits and adverse effects of newer pharmacotherapies and herbal treatments for depressive disorders in adults and adolescents. DATA SOURCES:English-language and no...

journal_title：Annals of internal medicine

authors： Williams JW Jr,Mulrow CD,Chiquette E,Noël PH,Aguilar C,Cornell J

更新日期：2000-05-02 00:00:00

abstract：:Lung cancer is the commonest cause of death from cancer in both men and women, with approximately 152,000 new cases and 139,000 deaths in 1988. The incidence and mortality rates are increasing rapidly in women. Two main tests have been used to screen for lung cancer: chest roentgenography and sputum cytology. Four rec...

journal_title：Annals of internal medicine

authors： Eddy DM

更新日期：1989-08-01 00:00:00

abstract：:Of 5379 patients who had received radiation treatment at our institution for benign conditions of the head and neck, 318 developed thyroid cancer 3 to 42 years later. We report follow-up observations (median interval from diagnosis to recurrence or last contact, 10 years; longest interval, 31) for 296 of these patient...

journal_title：Annals of internal medicine

authors： Schneider AB,Recant W,Pinsky SM,Ryo UY,Bekerman C,Shore-Freedman E

更新日期：1986-09-01 00:00:00

abstract：:The four main conceptual paradigms of basic biomedical research are that the explication of mechanisms is a primary goal of science; that scientific data must be "hard"; that formulation of hypotheses and counter-hypotheses is a principal creative challenge; and that experiments are the main mechanism for using scient...

journal_title：Annals of internal medicine

authors： Feinstein AR

更新日期：1983-09-01 00:00:00

abstract：OBJECTIVE:To determine whether protruding atheromas in the thoracic aorta are a risk factor for systemic embolization. DESIGN:Case-control study. SETTING:A referral hospital. PATIENTS:A total of 122 patients with a history of stroke, transient ischemic attack, or peripheral emboli and an equal number of age- and sex...

journal_title：Annals of internal medicine

authors： Tunick PA,Perez JL,Kronzon I

更新日期：1991-09-15 00:00:00

abstract：:This article applies major economic concepts, such as supply, demand, monopoly, monopsony, adverse selection, and moral hazard, to central features of U.S. health care. These illustrations help explain some of the principal problems of health policy-high cost and the uninsured-and why solutions are difficult to obtain...

journal_title：Annals of internal medicine

authors： Fuchs VR

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:The high prevalence of classic cardiac risk factors in patients with non-insulin-dependent diabetes mellitus does not explain the increased cardiovascular-related morbidity and mortality in these patients. Fibrinogen may have a role in this excess risk. OBJECTIVE:To evaluate the following in patients with n...

journal_title：Annals of internal medicine

authors： Bruno G,Cavallo-Perin P,Bargero G,Borra M,D'Errico N,Pagano G

更新日期：1996-10-15 00:00:00

abstract：:Streptococcus pneumoniae causes substantial morbidity and mortality. Incidence and severity are increased among populations with some chronic diseases. The currently available polyvalent polysaccharide vaccine induces antibody production among immunologically competent recipients against the 14 serotypes responsible f...

journal_title：Annals of internal medicine

authors： Schwartz JS

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:The long-term risk for fatal pulmonary embolism (PE) after treatment of venous thromboembolism (VTE) may be an important factor in the decision to discontinue this treatment. OBJECTIVE:To provide reliable and precise estimates of the annual risk for fatal PE and the case-fatality rate of disease recurrence ...

journal_title：Annals of internal medicine

authors： Douketis JD,Gu CS,Schulman S,Ghirarduzzi A,Pengo V,Prandoni P

更新日期：2007-12-04 00:00:00

abstract：:Tetanus is an expected complication when disasters strike in developing countries, where tetanus immunization coverage is often low or nonexistent. Collapsing structures and swirling debris inflict numerous crush injuries, fractures, and serious wounds. Clostridium tetani infects wounds contaminated with dirt, feces, ...

journal_title：Annals of internal medicine

authors： Afshar M,Raju M,Ansell D,Bleck TP

更新日期：2011-03-01 00:00:00

abstract：:Three patients with advanced Graves' ophthalmopathy were treated with cyclophosphamide. All had proptosis and diplopia. One patient had disabling iatrogenic Cushing's syndrome from steroid treatment of the ophthalmopathy and had undergone bilateral orbital decompression before cyclophosphamide therapy; steroids could ...

journal_title：Annals of internal medicine

authors： Bigos ST,Nisula BC,Daniels GH,Eastman RC,Johnston HH,Kohler PO

更新日期：1979-06-01 00:00:00

abstract：:The efficacy of corticosteroid treatment in the prophylaxis of the fat embolism syndrome was evaluated in a prospective, randomized, double-blind study of high-risk patients with long-bone fractures. Using a set of objective diagnostic criteria, we saw a significant difference in the incidence of the syndrome between ...

journal_title：Annals of internal medicine

authors： Schonfeld SA,Ploysongsang Y,DiLisio R,Crissman JD,Miller E,Hammerschmidt DE,Jacob HS

更新日期：1983-10-01 00:00:00

abstract：OBJECTIVE:To determine whether prolonging the duration of tamoxifen administration beyond the cessation of a combined chemotherapy regimen benefits patients with primary breast cancer with positive findings in axillary nodes who benefit initially from the combined regimen. DESIGN:Nonrandomized, nonconcurrent cohort st...

journal_title：Annals of internal medicine

authors： Fisher B,Brown A,Wolmark N,Redmond C,Wickerham DL,Wittliff J,Dimitrov N,Legault-Poisson S,Schipper H,Prager D

更新日期：1987-05-01 00:00:00