Epstein-Barr virus and human malignancy.

Abstract:

:The association of the Epstein-Barr virus and two human malignancies, Burkitt's lumphoma and nasopharyngeal carcinoma, is reviewed. Seroepidemiologic, virologic, and immunologic evidence is summarized, and several hypotheses regarding a possible etiologic role for the Epstein-Barr virus in these tumors are presented. With our current state of knowledge we cannot conclude that the Ipstein-Barr virus is oncogenic in man, nor can we yet ascertain the biological and clinical significance of its association with Burkitt's lymphoma and nasopharyngeal carcinoma.

journal_name

Ann Intern Med

authors

Ziegler JL,Magrath IT,Gerber P,Levine PH

doi

10.7326/0003-4819-86-3-323

subject

Has Abstract

pub_date

1977-03-01 00:00:00

pages

323-36

issue

3

eissn

0003-4819

issn

1539-3704

journal_volume

86

pub_type

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