Digitoxin elimination reduced during quinidine therapy.

abstract：OBJECTIVE:To determine the toxicity and efficacy of low-dose interferon-alpha therapy in inducing remissions and prolonging survival in patients with chronic myeloid leukemia. DESIGN:Phase II evaluation and comparison with historical control patients and other series in which the investigators used higher interferon-a...

journal_title：Annals of internal medicine

authors： Schofield JR,Robinson WA,Murphy JR,Rovira DK

更新日期：1994-11-15 00:00:00

abstract：BACKGROUND:In previous open-label noncomparative clinical trials, both fluconazole and itraconazole were effective therapy for progressive forms of coccidioidomycosis. OBJECTIVE:To determine whether fluconazole or itraconazole is superior for treatment of nonmeningeal progressive coccidioidal infections. DESIGN:Rando...

journal_title：Annals of internal medicine

authors： Galgiani JN,Catanzaro A,Cloud GA,Johnson RH,Williams PL,Mirels LF,Nassar F,Lutz JE,Stevens DA,Sharkey PK,Singh VR,Larsen RA,Delgado KL,Flanigan C,Rinaldi MG

更新日期：2000-11-07 00:00:00

abstract：:Traditionally, acupuncture is embedded in naturalistic theories that are compatible with Confucianism and Taoism. Such ideas as yin-yang, qi, dampness, and wind represent East Asian conceptual frameworks that emphasize the reliability of ordinary, human sensory awareness. Many physicians who practice acupuncture rejec...

journal_title：Annals of internal medicine

authors： Kaptchuk TJ

更新日期：2002-03-05 00:00:00

abstract：BACKGROUND:The current standard initial therapies for deep venous thrombosis are low-molecular-weight heparin and unfractionated heparin. In a dose-ranging study of patients with symptomatic deep venous thrombosis, fondaparinux had efficacy and a safety profile similar to those of low-molecular-weight heparin (daltepar...

journal_title：Annals of internal medicine

authors： Büller HR,Davidson BL,Decousus H,Gallus A,Gent M,Piovella F,Prins MH,Raskob G,Segers AE,Cariou R,Leeuwenkamp O,Lensing AW,Matisse Investigators.

更新日期：2004-06-01 00:00:00

abstract：:The content, role, and purpose of internal medicine, organized as an American specialty 100 years ago, have been marked by ambivalence from the beginning. Nevertheless, molded to a large extent by external events, including the strategic and symbolic importance of surgery in American medicine, the rise of university m...

journal_title：Annals of internal medicine

authors： Stevens R

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Oral sildenafil and intravenous epoprostenol have independently been shown to be effective in patients with pulmonary arterial hypertension. OBJECTIVE:To investigate the effect of adding oral sildenafil to long-term intravenous epoprostenol in patients with pulmonary arterial hypertension. DESIGN:A 16-week...

journal_title：Annals of internal medicine

authors： Simonneau G,Rubin LJ,Galiè N,Barst RJ,Fleming TR,Frost AE,Engel PJ,Kramer MR,Burgess G,Collings L,Cossons N,Sitbon O,Badesch DB,PACES Study Group.

更新日期：2008-10-21 00:00:00

abstract：Background:Older adults with acute myocardial infarction (AMI) have higher prevalence of functional impairments, including deficits in cognition, strength, and sensory domains, than their younger counterparts. Objective:To develop and evaluate the prognostic utility of a risk model for 6-month post-AMI mortality in ol...

journal_title：Annals of internal medicine

authors： Dodson JA,Hajduk AM,Geda M,Krumholz HM,Murphy TE,Tsang S,Tinetti ME,Nanna MG,McNamara R,Gill TM,Chaudhry SI

更新日期：2020-01-07 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of fluconazole for prevention of fungal infections. DESIGN:A randomized, placebo-controlled, double-blind, multicenter trial. PATIENTS:Adults (257) undergoing chemotherapy for acute leukemia. INTERVENTION:Patients were randomly assigned to receive either fluconazole (400...

journal_title：Annals of internal medicine

authors： Winston DJ,Chandrasekar PH,Lazarus HM,Goodman JL,Silber JL,Horowitz H,Shadduck RK,Rosenfeld CS,Ho WG,Islam MZ,Buell DN

更新日期：1993-04-01 00:00:00

abstract：:Essential trace elements such as zinc, iron, and copper participate in various enzyme reactions directly related to the regulation of blood pressure and indirectly related to generation of oxidative metabolic energy, alterations in blood lipid levels, and alterations in taste acuity. The toxicological action of severa...

journal_title：Annals of internal medicine

authors： Saltman P

更新日期：1983-05-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the effectiveness of chemotherapy and adjunctive surgery in managing patients with advanced seminoma. DESIGN:Nonrandomized prospective clinical trial of chemotherapy in a cohort of patients with advanced seminoma. SETTING:Referral cancer hospital. PATIENTS:Consecutive sample of 62 patien...

journal_title：Annals of internal medicine

authors： Motzer RJ,Bosl GJ,Geller NL,Penenberg D,Yagoda A,Golbey R,Whitmore WF Jr,Fair WR,Sogani P,Herr H

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVE:To determine risk factors for community-acquired and nosocomial group B streptococcal disease in adults. DESIGN:Case-control study. SETTING:3 metropolitan areas in the United States with an aggregate population of 6.6 million persons. PATIENTS:219 nonpregnant adults with invasive group B streptococcal infe...

journal_title：Annals of internal medicine

authors： Jackson LA,Hilsdon R,Farley MM,Harrison LH,Reingold AL,Plikaytis BD,Wenger JD,Schuchat A

更新日期：1995-09-15 00:00:00

abstract：:Sideroblastic anemia after treatment for Hogdkin's disease was seen in two patients 3 years after completion of radiation therapy and chemotherapy. This was followed in both by the development of myelomonoblastic leukemia. No evidence of recurrent Hodgkin's disease was present in either patient. Our observation sugges...

journal_title：Annals of internal medicine

authors： Kitahara M,Cosgriff TM,Eyre HJ

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:Patients with chronic obstructive pulmonary disease (COPD) frequently develop exacerbations, leading to major clinical and health resource use ramifications. OBJECTIVE:To prospectively evaluate the effectiveness of a long-acting inhaled anticholinergic bronchodilator, tiotropium, in reducing COPD exacerbati...

journal_title：Annals of internal medicine

authors： Niewoehner DE,Rice K,Cote C,Paulson D,Cooper JA Jr,Korducki L,Cassino C,Kesten S

更新日期：2005-09-06 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and symptoms of and risk factors for biliary sludge and gallstones during pregnancy and to assess the natural history of these conditions in the first year after delivery. DESIGN:Cohort study. PATIENTS:A total of 272 pregnant women recruited in the first trimester. MEASUREMENTS:Bi...

journal_title：Annals of internal medicine

authors： Maringhini A,Ciambra M,Baccelliere P,Raimondo M,Orlando A,Tinè F,Grasso R,Randazzo MA,Barresi L,Gullo D,Musico M,Pagliaro L

更新日期：1993-07-15 00:00:00

abstract：:Two patients had recurrent facial edema and peripheral blood eosinophilia. One patient showed a marked increase in the serum level of the eosinophil granule major basic protein. In both patients, skin biopsy samples showed nonspecific mononuclear cell inflammation with few eosinophils. However, immunofluorescence stai...

journal_title：Annals of internal medicine

authors： Songsiridej V,Peters MS,Dor PJ,Ackerman SJ,Gleich GJ,Busse WW

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Current magnetic resonance techniques generate high signal from venous blood and show thrombi as filling defects. Magnetic resonance direct thrombus imaging (MRDTI) directly visualizes acute thrombus. OBJECTIVE:To determine the accuracy of MRDTI for diagnosis of acute symptomatic deep venous thrombosis (DVT...

journal_title：Annals of internal medicine

authors： Fraser DG,Moody AR,Morgan PS,Martel AL,Davidson I

更新日期：2002-01-15 00:00:00

abstract：:Immediately after the liberation of Kuwait by a coalition of allied forces in March 1991, representatives of Physicians for Human Rights traveled to Kuwait and conducted an inquiry into human rights violations allegedly perpetrated by Iraqi forces. The inquiry focused on the abuses that were said to have occurred in h...

journal_title：Annals of internal medicine

authors： Brennan TA,Kirschner R

更新日期：1992-07-01 00:00:00

abstract：DESCRIPTION:The Women's Preventive Services Initiative (WPSI), a national coalition of women's health professional organizations and patient representatives, developed a recommendation on screening for anxiety in adolescent and adult women to improve detection; achieve earlier diagnosis and treatment; and improve healt...

journal_title：Annals of internal medicine

authors： Gregory KD,Chelmow D,Nelson HD,Van Niel MS,Conry JA,Garcia F,Kendig SM,O'Reilly N,Qaseem A,Ramos D,Salganicoff A,Son S,Wood JK,Zahn C,Women’s Preventive Services Initiative.

更新日期：2020-07-07 00:00:00

abstract：:Adult T-cell leukemia associated with human T-cell leukemia virus type I (HTLV-I) is characterized by a clonal expansion of a CD4-positive subset of T lymphocytes that constitutively express high numbers of interleukin-2 receptors and that frequently infiltrate the skin; osteolytic bone lesions, and hypercalcemia. Usi...

journal_title：Annals of internal medicine

authors： Marcon L,Rubin LA,Kurman CC,Fritz ME,Longo DL,Uchiyama T,Edwards BK,Nelson DL

更新日期：1988-08-15 00:00:00

abstract：:Eight patients developed grand mal seizures during intravenous theophylline therapy. None had a history of neurologic disorder, and all were acutely ill with severe pulmonary or cardiovascular disease, or both. Serum theophylline concentrations obtained within 1 hour of the seizure ranged from 25 mug/ml to 70mug/ml, w...

journal_title：Annals of internal medicine

authors： Zwillich CW,Sutton FD,Neff TA,Cohn WM,Matthay RA,Weinberger MM

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:Pay-for-performance (P4P) is increasingly touted as a means to improve health care quality. PURPOSE:To evaluate the effect of P4P remuneration targeting individual health care providers. DATA SOURCES:MEDLINE, EMBASE, Cochrane Library, OpenSIGLE, Canadian Evaluation Society Unpublished Literature Bank, New ...

journal_title：Annals of internal medicine

authors： Houle SK,McAlister FA,Jackevicius CA,Chuck AW,Tsuyuki RT

更新日期：2012-12-18 00:00:00

abstract：:Giant cell tumor of bone is a rare, but well-recognized complication of Paget's disease of bone. In contrast, giant cell reparative granuloma (a benign tumor of the jaws occurring primarily in young adults) has never been described in association with Paget's disease. Five patients had giant cell lesions complicating ...

journal_title：Annals of internal medicine

authors： Upchurch KS,Simon LS,Schiller AL,Rosenthal DI,Campion EW,Krane SM

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The optimal strategy for diagnosis of deep venous thrombosis (DVT) is less well established for the upper extremities than for the lower extremities. Duplex color ultrasonography can be difficult to perform in the upper extremities because of their anatomy, and contrast venography is often indicated. Moreove...

journal_title：Annals of internal medicine

authors： Baarslag HJ,van Beek EJ,Koopman MM,Reekers JA

更新日期：2002-06-18 00:00:00

abstract：OBJECTIVE:To evaluate the influence of a human immunodeficiency virus (HIV) vaccine given to uninfected volunteers on the interpretation of serodiagnostic HIV test results. DESIGN:Retrospective cohort study. SETTING:5 AIDS Vaccine Evaluation Units funded by the National Institute of Allergy and Infectious Diseases. ...

journal_title：Annals of internal medicine

authors： Belshe RB,Clements ML,Keefer MC,Graham BS,Corey L,Sposto R,Wescott S,Lawrence D

更新日期：1994-10-15 00:00:00

abstract：:Two patients presenting with nephrotic syndrome but without evidence of collagen vascular disease had organized glomerular immune deposits with a "fingerprint" pattern. This finding has been previously associated with lupus nephritis and, in our institution, has been seen in 6% of the biopsy specimens from patients wi...

journal_title：Annals of internal medicine

authors： Alpers CE,Hopper J Jr,Bernstein MJ,Biava CG

更新日期：1984-01-01 00:00:00

abstract：:This paper outlines the clinical, serologic, and immunogenetic differences and similarities of Sjögren's syndrome alone (primary) and Sjögren's syndrome associated with rheumatoid arthritis and systemic lupus erythematosus (secondary). The immunoregulation in Sjögren's syndrome is discussed and the incidence of immune...

journal_title：Annals of internal medicine

authors： Moutsopoulos HM,Chused TM,Mann DL,Klippel JH,Fauci AS,Frank MM,Lawley TJ,Hamburger MI

更新日期：1980-02-01 00:00:00

abstract：:Three patients with polymyositis had elevated serum levels of creatine kinase MB isoenzyme. The presence of this isoenzyme is used extensively to diagnose myocardial infarction, but the isoenzyme is also found in sera of patients with primary muscular and neuromuscular disorders. We studied cardiac function in two of ...

journal_title：Annals of internal medicine

authors： Larca LJ,Coppola JT,Honig S

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Benign reductions in neutrophil counts may be more common at certain ages and in certain ethnic groups and may be affected by sex and smoking status. OBJECTIVE:To determine differences in neutrophil counts in the U.S. population according to ethnicity, age, sex, and smoking status. DESIGN:Population-based,...

journal_title：Annals of internal medicine

authors： Hsieh MM,Everhart JE,Byrd-Holt DD,Tisdale JF,Rodgers GP

更新日期：2007-04-03 00:00:00

abstract：BACKGROUND:Tobacco dependence is a chronic, relapsing condition that may require extended treatment. OBJECTIVE:To assess whether extended-duration transdermal nicotine therapy increases abstinence from tobacco more than standard-duration therapy in adult smokers. DESIGN:Parallel randomized, placebo-controlled trial f...

journal_title：Annals of internal medicine

authors： Schnoll RA,Patterson F,Wileyto EP,Heitjan DF,Shields AE,Asch DA,Lerman C

更新日期：2010-02-02 00:00:00

abstract：:Axial, dual spin-echo magnetic resonance (MR) images, taken at the level of the pulmonary arteries and gated to the cardiac cycle, were qualitatively and quantitatively evaluated in nine patients with primary pulmonary arterial hypertension and six controls. In controls and patients, intravascular signal intensity was...

journal_title：Annals of internal medicine

authors： von Schulthess GK,Fisher MR,Higgins CB

更新日期：1985-09-01 00:00:00