Daily aspirin for primary prevention increased risk for major GI bleeding in healthy older adults.

abstract：BACKGROUND:Homeless persons have high mortality rates. OBJECTIVE:To ascertain causes of death in a group of homeless persons. DESIGN:Cohort study. PATIENTS:17,292 adults seen by the Boston Health Care for the Homeless Program from 1988 to 1993. MEASUREMENTS:Cause-specific mortality rates adjusted for race and rate ...

journal_title：Annals of internal medicine

authors： Hwang SW,Orav EJ,O'Connell JJ,Lebow JM,Brennan TA

更新日期：1997-04-15 00:00:00

abstract：:Of 5379 patients who had received radiation treatment at our institution for benign conditions of the head and neck, 318 developed thyroid cancer 3 to 42 years later. We report follow-up observations (median interval from diagnosis to recurrence or last contact, 10 years; longest interval, 31) for 296 of these patient...

journal_title：Annals of internal medicine

authors： Schneider AB,Recant W,Pinsky SM,Ryo UY,Bekerman C,Shore-Freedman E

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Radiation therapy is one of many treatment options for patients with prostate cancer. PURPOSE:To update findings on the clinical and biochemical outcomes of radiation therapies for localized prostate cancer. DATA SOURCES:MEDLINE (2007 through March 2011) and the Cochrane Central Register of Controlled Tria...

journal_title：Annals of internal medicine

authors： Bannuru RR,Dvorak T,Obadan N,Yu WW,Patel K,Chung M,Ip S

更新日期：2011-08-02 00:00:00

abstract：PURPOSE:Chemoprevention offers promise as a strategy for reducing morbidity and mortality from breast cancer in women. This review examined the evidence for the effectiveness of chemoprevention in women without a history of breast cancer. DATA SOURCES:MEDLINE (1966 to December 2001). STUDY SELECTION:English-language,...

journal_title：Annals of internal medicine

authors： Kinsinger LS,Harris R,Woolf SH,Sox HC,Lohr KN

更新日期：2002-07-02 00:00:00

abstract：:We isolated a high molecular weight antigen of the Legionnaires' disease (LD) bacterium by column chromatography. The antigen was composed of 35% carbohydrate, 2.6% protein, 1.8% phospholipid, and 1% 2-keto-3-deoxyoctonate and was important in the host's antibody response because it inhibited the indirect immunofluore...

journal_title：Annals of internal medicine

authors： Johnson W,Elliott JA,Helms CM,Renner ED

更新日期：1979-04-01 00:00:00

abstract：:Between 20 July and 15 Octoboer 1975, five cases of human infection with Babesia microti were diagnosed on Nantucket Island, Massachusetts. The illness was characterized by fever, drenching sweats, shaking chills, myalgia, arthralgia, extreme fatigue, and a mild-to-moderate hemolytic anemia. None of the patients had a...

journal_title：Annals of internal medicine

authors： Reubush TK 2nd,Cassaday PB,Marsh HJ,Lisker SA,Voorhees DB,Mahoney EB,Healy GR

更新日期：1977-01-01 00:00:00

abstract：:Barrett's esophagus denotes the presence of columnar epithelium in the esophagus instead of the usual stratified squamous epithelium. Barrett's esophagus had been thought to represent a mediastinal extension of the stomach in patients with a congenital short esophagus. Subsequent clinical and experimental data have es...

journal_title：Annals of internal medicine

authors： Bozymski EM,Herlihy KJ,Orlando RC

更新日期：1982-07-01 00:00:00

abstract：:During 1973 and 1974, we looked for cases of Colorado tick fever throughout Colorado; 228 cases were identified. Although 90% of the patients reported exposure to ticks before illness, only 52% were aware of an actual tick bite. Typical symptoms of fever, myalgia, and headache were common, but gastrointestinal symptom...

journal_title：Annals of internal medicine

authors： Goodpasture HC,Poland JD,Francy DB,Bowen GS,Horn KA

更新日期：1978-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of fluconazole for prevention of fungal infections. DESIGN:A randomized, placebo-controlled, double-blind, multicenter trial. PATIENTS:Adults (257) undergoing chemotherapy for acute leukemia. INTERVENTION:Patients were randomly assigned to receive either fluconazole (400...

journal_title：Annals of internal medicine

authors： Winston DJ,Chandrasekar PH,Lazarus HM,Goodman JL,Silber JL,Horowitz H,Shadduck RK,Rosenfeld CS,Ho WG,Islam MZ,Buell DN

更新日期：1993-04-01 00:00:00

abstract：OBJECTIVE:To develop criteria for interpreting results of the metyrapone test for the differential diagnosis of the adrenocorticotropin (ACTH)-dependent Cushing syndrome and to compare its diagnostic accuracy with that of the high-dose dexamethasone suppression test. DESIGN:Retrospective cohort study. SETTING:Inpatie...

journal_title：Annals of internal medicine

authors： Avgerinos PC,Yanovski JA,Oldfield EH,Nieman LK,Cutler GB Jr

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Preventive therapy is an important element of syphilis control efforts. No currently recommended, single-dose alternatives to penicillin G benzathine are available for treatment of incubating syphilis. OBJECTIVE:To evaluate the use of a single 1.0-g dose of azithromycin for treatment of persons recently exp...

journal_title：Annals of internal medicine

authors： Hook EW 3rd,Stephens J,Ennis DM

更新日期：1999-09-21 00:00:00

abstract：BACKGROUND:Telaprevir (TVR) plus peginterferon-α2a (PEG-IFN-α2a) and ribavirin substantially increases treatment efficacy for genotype 1 chronic hepatitis C virus (HCV) infection versus PEG-IFN-α2a-ribavirin alone. Its safety and efficacy in patients with HCV and HIV-1 are unknown. OBJECTIVE:To assess the safety and e...

journal_title：Annals of internal medicine

authors： Sulkowski MS,Sherman KE,Dieterich DT,Bsharat M,Mahnke L,Rockstroh JK,Gharakhanian S,McCallister S,Henshaw J,Girard PM,Adiwijaya B,Garg V,Rubin RA,Adda N,Soriano V

更新日期：2013-07-16 00:00:00

abstract：Background:Zika virus has spread rapidly in the Americas and has been imported into many nonendemic countries by travelers. Objective:To describe clinical manifestations and epidemiology of Zika virus disease in travelers exposed in the Americas. Design:Descriptive, using GeoSentinel records. Setting:63 travel and t...

journal_title：Annals of internal medicine

authors： Hamer DH,Barbre KA,Chen LH,Grobusch MP,Schlagenhauf P,Goorhuis A,van Genderen PJ,Molina I,Asgeirsson H,Kozarsky PE,Caumes E,Hagmann SH,Mockenhaupt FP,Eperon G,Barnett ED,Bottieau E,Boggild AK,Gautret P,Hynes NA,Kuhn

更新日期：2017-01-17 00:00:00

abstract：:Relapsing polychondritis, an uncommon, chronic, multisystem disorder characterized by recurrent episodes of inflammation of cartilaginous tissues, can be life-threatening, debilitating, and difficult to diagnose. This review is based on the authors' experience with 36 patients with relapsing polychondritis who were fo...

journal_title：Annals of internal medicine

authors： Trentham DE,Le CH

更新日期：1998-07-15 00:00:00

abstract：:Since 1970, forty-two patients with pulmonary hypertension due to chronic, thromboembolic obstruction of the major pulmonary arteries have had pulmonary thromboendarterectomy at the University of California, San Diego, and the San Diego Veterans Medical Centers. Duration of symptoms before admission averaged 4.4 years...

journal_title：Annals of internal medicine

authors： Moser KM,Daily PO,Peterson K,Dembitsky W,Vapnek JM,Shure D,Utley J,Archibald C

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Travelers' diarrhea causes substantial morbidity and postinfectious irritable bowel syndrome. OBJECTIVE:To evaluate nonabsorbable rifaximin for prevention of travelers' diarrhea. DESIGN:Randomized, double-blind, placebo-controlled clinical trial. SETTING:Guadalajara, Mexico. PARTICIPANTS:U.S. students. ...

journal_title：Annals of internal medicine

authors： DuPont HL,Jiang ZD,Okhuysen PC,Ericsson CD,de la Cabada FJ,Ke S,DuPont MW,Martinez-Sandoval F

更新日期：2005-05-17 00:00:00

abstract：:Polysaccharide vaccines against diseases caused by Neisseria meningitidis serogroups A and C meningococci are now licensed in the United States. They are prepared as monovalent and as bivalent antigens. This statement summarizes available information on these antigen and offers guidance regarding their role in the con...

journal_title：Annals of internal medicine

authors：

更新日期：1976-02-01 00:00:00

abstract：:Reversible cerebral vasoconstriction syndromes (RCVS) comprise a group of diverse conditions, all characterized by reversible multifocal narrowing of the cerebral arteries heralded by sudden (thunderclap), severe headaches with or without associated neurologic deficits. Reversible cerebral vasoconstriction syndromes a...

journal_title：Annals of internal medicine

authors： Calabrese LH,Dodick DW,Schwedt TJ,Singhal AB

更新日期：2007-01-02 00:00:00

abstract：BACKGROUND:Castleman disease, an unusual condition of unknown cause consisting of a massive proliferation of lymphoid tissue, remains a clinicopathologic diagnosis. Three histologic variants (hyaline vascular, plasma-cell, and mixed) and two clinical types (localized and multicentric) of Castleman disease have been des...

journal_title：Annals of internal medicine

authors： Herrada J,Cabanillas F,Rice L,Manning J,Pugh W

更新日期：1998-04-15 00:00:00

abstract：OBJECTIVE:To assess the safety and efficacy of intravenous adenosine in terminating acute episodes of paroxysmal supraventricular tachycardia. DESIGN:Two prospective, double-blind, randomized, placebo-controlled trials to evaluate dose response in patients receiving adenosine and to compare the effects of adenosine wi...

journal_title：Annals of internal medicine

authors： DiMarco JP,Miles W,Akhtar M,Milstein S,Sharma AD,Platia E,McGovern B,Scheinman MM,Govier WC

更新日期：1990-07-15 00:00:00

abstract：OBJECTIVE:To determine in female tennis and squash players the effect of biological age (that is, the starting age of playing relative to the age at menarche) at which tennis or squash playing was started on the difference in bone mineral content between the playing and non-playing arms. DESIGN:Cross-sectional study. ...

journal_title：Annals of internal medicine

authors： Kannus P,Haapasalo H,Sankelo M,Sievänen H,Pasanen M,Heinonen A,Oja P,Vuori I

更新日期：1995-07-01 00:00:00

abstract：:Treatment advances and outcomes data have raised new concerns about how to optimize care for patients with HIV infection. This paper reviews evidence on 1) the relation between experience and type of training and patient outcomes, 2) the relation between the components of primary care and patient outcomes, and 3) prim...

journal_title：Annals of internal medicine

authors： Hecht FM,Wilson IB,Wu AW,Cook RL,Turner BJ

更新日期：1999-07-20 00:00:00

abstract：:Plasma lipid and lipoprotein-cholesterol levels were measured in 10 insulin-dependent (Type I) diabetics taking their usual dose of conventionally administered insulin during 6 months of a continuous subcutaneous insulin infusion delivered with a small, portable, battery-powered pump. With this insulin delivery system...

journal_title：Annals of internal medicine

authors： Dunn FL,Pietri A,Raskin P

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Studies suggest that vitamin D supplementation may reduce cancer and fracture risks. PURPOSE:To examine the benefits and harms of vitamin D with or without calcium supplementation on clinical outcomes of cancer and fractures in adults. DATA SOURCES:English-language studies identified from MEDLINE and the C...

journal_title：Annals of internal medicine

authors： Chung M,Lee J,Terasawa T,Lau J,Trikalinos TA

更新日期：2011-12-20 00:00:00

abstract：:Colony-stimulating factors are growth factors responsible for the proliferation and the maturation of bone marrow stem cells to fully differentiated granulocytes and monocytes. In addition to their effects on hematopoiesis, some colony-stimulating factors prime mature cells for enhanced chemotaxis, phagocytosis, and k...

journal_title：Annals of internal medicine

authors： Weisbart RH,Gasson JC,Golde DW

更新日期：1989-02-15 00:00:00

abstract：BACKGROUND:Previous studies suggest that patients hospitalized with acute myocardial infarction (MI) in December have poor outcomes, and some studies have hypothesized that the cause may be the infrequent use of evidence-based therapies during the December holiday season. OBJECTIVE:To compare the care and outcomes of ...

journal_title：Annals of internal medicine

authors： Meine TJ,Patel MR,DePuy V,Curtis LH,Rao SV,Gersh BJ,Schulman KA,Jollis JG

更新日期：2005-10-04 00:00:00

abstract：DESCRIPTION:Update of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for bladder cancer. METHODS:The USPSTF performed a targeted literature search for new evidence on the benefits and harms of screening, the accuracy of primary care-feasible screening tests, and the benefit...

journal_title：Annals of internal medicine

authors： Moyer VA,U.S. Preventive Services Task Force.

更新日期：2011-08-16 00:00:00

abstract：:Access to information about clinical trials is important to researchers, health care professionals, and patients. Many have argued for the establishment of clinical trials registries, citing their substantial benefits. Although some registries do exist, it has been difficult to create comprehensive, easily accessible ...

journal_title：Annals of internal medicine

authors： McCray AT

更新日期：2000-10-17 00:00:00

abstract：:This paper outlines the clinical, serologic, and immunogenetic differences and similarities of Sjögren's syndrome alone (primary) and Sjögren's syndrome associated with rheumatoid arthritis and systemic lupus erythematosus (secondary). The immunoregulation in Sjögren's syndrome is discussed and the incidence of immune...

journal_title：Annals of internal medicine

authors： Moutsopoulos HM,Chused TM,Mann DL,Klippel JH,Fauci AS,Frank MM,Lawley TJ,Hamburger MI

更新日期：1980-02-01 00:00:00

abstract：:We have seen two patients whose hepatitis was due to the administration of aprindine, a new antiarrhythmic agent. In both patients evidence of hepatitis appeared within 3 weeks of initiating aprindine therapy and resolved rapidly when the drug was withdrawn. The reintroduction of aprindine in one patient was associate...

journal_title：Annals of internal medicine

authors： Herlong HF,Reid PR,Boitnott JK,Maddrey WC

更新日期：1978-09-01 00:00:00