Comparative evaluation of radiation treatments for clinically localized prostate cancer: an updated systematic review.

abstract：:The new knowledge of the regulation of cell growth and the genetic and biochemical changes that lead to malignancy have created many new opportunities for cancer drug discovery. These new targets include oncogenes, growth factors and their receptors, signal transduction pathways, and cell differentiation signals. Atte...

journal_title：Annals of internal medicine

authors： Chabner BA

更新日期：1993-04-15 00:00:00

abstract：:Between 20 July and 15 Octoboer 1975, five cases of human infection with Babesia microti were diagnosed on Nantucket Island, Massachusetts. The illness was characterized by fever, drenching sweats, shaking chills, myalgia, arthralgia, extreme fatigue, and a mild-to-moderate hemolytic anemia. None of the patients had a...

journal_title：Annals of internal medicine

authors： Reubush TK 2nd,Cassaday PB,Marsh HJ,Lisker SA,Voorhees DB,Mahoney EB,Healy GR

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Injection insulin therapy is not readily accepted by patients and many health care providers; therefore, less invasive options for insulin therapy are desirable. PURPOSE:To examine the efficacy, safety, and patient acceptability of inhaled insulin therapy in nonpregnant adults with diabetes mellitus. DATA ...

journal_title：Annals of internal medicine

authors： Ceglia L,Lau J,Pittas AG

更新日期：2006-11-07 00:00:00

abstract：BACKGROUND:The appropriate duration of therapy for catheter-associated Staphylococcus aureus bacteremia is controversial. Conventional practice dictates that all patients receive prolonged courses of intravenous antibiotics. Some clinicians recommend abbreviated therapeutic courses, but an alternate approach involves p...

journal_title：Annals of internal medicine

authors： Rosen AB,Fowler VG Jr,Corey GR,Downs SM,Biddle AK,Li J,Jollis JG

更新日期：1999-05-18 00:00:00

abstract：Background:In 1994, 40% of U.S. gun owners who had recently acquired a firearm did so without a background check. No contemporary estimates exist. Objective:To estimate the proportion of current U.S. gun owners who acquired their most recent firearm without a background check, by time since and manner of acquisition, ...

journal_title：Annals of internal medicine

authors： Miller M,Hepburn L,Azrael D

更新日期：2017-02-21 00:00:00

abstract：:A controlled clinical trial compared three-drug and four-drug combination chemotherapy in 109 patients with advanced small-cell anaplastic carcinoma of the lung. The combination of vincristine, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU), cyclophosphamide, and methotrexate was significantly superior to the com...

journal_title：Annals of internal medicine

authors： Hansen HH,Dombernowsky P,Hansen M,Hirsch F

更新日期：1978-08-01 00:00:00

abstract：:As a result of important advances in medical imaging, the oral cholecystogram is no longer the primary test of gallbladder function and anatomy. Real-time ultrasonography and cholescintigraphy, both highly sensitive and specific tests, are the two major methods for assessing gallbladder pathology. Oral cholecystograph...

journal_title：Annals of internal medicine

authors： Marton KI,Doubilet P

更新日期：1988-11-01 00:00:00

abstract：:We treated 289 men with nongonococcal urethritis in a randomized, double-blind study with minocycline, 100 mg once or twice daily for 7 or 21 days. Ureaplasma urealyticum was isolated before treatment from 167 (58%). The pretherapy isolates from 82 men re-examined 6 to 8 days after initiation of treatment were viable....

journal_title：Annals of internal medicine

authors： Stimson JB,Hale J,Bowie WR,Holmes KK

更新日期：1981-02-01 00:00:00

abstract：:Severe hypocalcemia secondary to magnesium depletion has been described in numerous patients with gastrointestinal disorders. The development of profound hypomagnesemia in chronic renal disease is a rare finding. We studied three patients with advanced renal failure and magnesium depletion. Severe hypocalcemia also wa...

journal_title：Annals of internal medicine

authors： Mennes P,Rosenbaum R,Martin K,Slatopolsky E

更新日期：1978-02-01 00:00:00

abstract：:A patient with a retained bullet developed lead poisoning in association with thyrotoxicosis. The clinical and laboratory data suggest that lead was mobilized from an increased mobile bone pool during the hypermetabolic period with resultant poisoning. The findings give factual support to earlier concepts that lead po...

journal_title：Annals of internal medicine

authors： Cagin CR,Diloy-Puray M,Westerman MP

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Some health plans profile physicians on the basis of their relative costs and use these profiles to assign physicians to cost categories. Physician organizations have questioned whether the rules used to attribute costs to a physician affect the cost category to which that physician is assigned. OBJECTIVE:T...

journal_title：Annals of internal medicine

authors： Mehrotra A,Adams JL,Thomas JW,McGlynn EA

更新日期：2010-05-18 00:00:00

abstract：BACKGROUND:The high prevalence of classic cardiac risk factors in patients with non-insulin-dependent diabetes mellitus does not explain the increased cardiovascular-related morbidity and mortality in these patients. Fibrinogen may have a role in this excess risk. OBJECTIVE:To evaluate the following in patients with n...

journal_title：Annals of internal medicine

authors： Bruno G,Cavallo-Perin P,Bargero G,Borra M,D'Errico N,Pagano G

更新日期：1996-10-15 00:00:00

abstract：OBJECTIVE:To estimate relative risk of mortality and median life expectancy for patients with classic hemophilia by a life-table analysis, taking into account deaths that may have occurred in infancy or childhood before the onset of symptoms. DESIGN:Retrospective chart review of clinical series. SETTING:Referral-base...

journal_title：Annals of internal medicine

authors： Jones PK,Ratnoff OD

更新日期：1991-04-15 00:00:00

abstract：OBJECTIVE:To evaluate the incidence and symptoms of and risk factors for biliary sludge and gallstones during pregnancy and to assess the natural history of these conditions in the first year after delivery. DESIGN:Cohort study. PATIENTS:A total of 272 pregnant women recruited in the first trimester. MEASUREMENTS:Bi...

journal_title：Annals of internal medicine

authors： Maringhini A,Ciambra M,Baccelliere P,Raimondo M,Orlando A,Tinè F,Grasso R,Randazzo MA,Barresi L,Gullo D,Musico M,Pagliaro L

更新日期：1993-07-15 00:00:00

abstract：:In five patients with hypertension and marked impairment of renal function due to renal artery stenosis in a solitary functioning kidney, a nonsurgical technique, percutaneous transluminal angioplasty, was used to dilate the stenotic renal artery. Blood pressure improved in all five patients, and renal function improv...

journal_title：Annals of internal medicine

authors： Weinberger MH,Yune HY,Grim CE,Luft FC,Klatte EC,Donohue JP

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:The choice of antiplatelet therapy after acute coronary syndrome (ACS) is complicated: Ticagrelor and prasugrel are novel alternatives to clopidogrel, patients with some genotypes may not respond to clopidogrel, and low-cost generic formulations of clopidogrel are available. OBJECTIVE:To determine the most ...

journal_title：Annals of internal medicine

authors： Kazi DS,Garber AM,Shah RU,Dudley RA,Mell MW,Rhee C,Moshkevich S,Boothroyd DB,Owens DK,Hlatky MA

更新日期：2014-02-18 00:00:00

abstract：Background:Older adults with acute myocardial infarction (AMI) have higher prevalence of functional impairments, including deficits in cognition, strength, and sensory domains, than their younger counterparts. Objective:To develop and evaluate the prognostic utility of a risk model for 6-month post-AMI mortality in ol...

journal_title：Annals of internal medicine

authors： Dodson JA,Hajduk AM,Geda M,Krumholz HM,Murphy TE,Tsang S,Tinetti ME,Nanna MG,McNamara R,Gill TM,Chaudhry SI

更新日期：2020-01-07 00:00:00

abstract：:The coexistence of chronic idiopathic thrombocytopenic purpura and myasthenia gravis has been infrequently reported. We report another case and show the coexistence of autoantibodies to the platelet glycoprotein IIb and IIIa complex and the acetylcholine receptor. Autoantibody levels were followed during 8 weeks of tr...

journal_title：Annals of internal medicine

authors： Anderson MJ,Woods VL Jr,Tani P,Lindstrom JM,Schmidt D,McMillan R

更新日期：1984-06-01 00:00:00

abstract：Background:FLU-v is a broad-spectrum influenza vaccine that induces antibodies and cell-mediated immunity. Objective:To compare the safety, immunogenicity, and exploratory efficacy of different formulations and dosing regimens of FLU-v versus placebo. Design:Randomized, double-blind, placebo-controlled, single-center...

journal_title：Annals of internal medicine

authors： Pleguezuelos O,Dille J,de Groen S,Oftung F,Niesters HGM,Islam MA,Næss LM,Hungnes O,Aldarij N,Idema DL,Perez AF,James E,Frijlink HW,Stoloff G,Groeneveld P,Hak E

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:Few treatments exist for coronavirus disease 2019 (COVID-19). PURPOSE:To evaluate the effectiveness and harms of remdesivir for COVID-19. DATA SOURCES:Several databases, tables of contents of journals, and U.S. Food and Drug Administration and company websites were searched from 1 January through 31 August...

journal_title：Annals of internal medicine

authors： Wilt TJ,Kaka AS,MacDonald R,Greer N,Obley A,Duan-Porter W

更新日期：2020-10-05 00:00:00

abstract：:Infection with human immunodeficiency virus (HIV) may cause viral antigenemia, detected primarily as p24 viral core protein. Among 16 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex studied serially, 12 had or developed antigenemia ranging from 16 to 3006 pg/mL in plasma. The level ...

journal_title：Annals of internal medicine

authors： Jackson GG,Paul DA,Falk LA,Rubenis M,Despotes JC,Mack D,Knigge M,Emeson EE

更新日期：1988-02-01 00:00:00

abstract：:Much of what is formally taught in medicine is about the knowledge, skills, and behaviors required of a physician, including how to express compassion and respect for patients at the bedside. What is learned, however, includes not only admirable qualities but also behaviors and qualities that are inconsistent with eth...

journal_title：Annals of internal medicine

authors： Lehmann LS,Sulmasy LS,Desai S,ACP Ethics, Professionalism and Human Rights Committee.

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:Four months of rifampin treatment for latent tuberculosis infection is safer, has superior treatment completion rates, and is as effective as 9 months of isoniazid. However, daily medication costs are higher for a 4-month rifampin regimen than a 9-month isoniazid regimen. OBJECTIVE:To compare health care us...

journal_title：Annals of internal medicine

authors： Bastos ML,Campbell JR,Oxlade O,Adjobimey M,Trajman A,Ruslami R,Kim HJ,Baah JO,Toelle BG,Long R,Hoeppner V,Elwood K,Al-Jahdali H,Apriani L,Benedetti A,Schwartzman K,Menzies D

更新日期：2020-08-04 00:00:00

abstract：:A prospective pretreatment staging evaluation was done on 49 consecutive patients with mycosis fungoides or the Sézary syndrome to study patterns of disease spread and prognostic factors. Routine staging procedures included complete blood count, blood chemistries, chest roentgenogram, lymphangiogram, radionuclide scan...

journal_title：Annals of internal medicine

authors： Bunn PA Jr,Huberman MS,Whang-Peng J,Schechter GP,Guccion JG,Matthews MJ,Gazdar AF,Dunnick NR,Fischmann AB,Ihde DC,Cohen MH,Fossieck B,Minna JD

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:Oral sildenafil and intravenous epoprostenol have independently been shown to be effective in patients with pulmonary arterial hypertension. OBJECTIVE:To investigate the effect of adding oral sildenafil to long-term intravenous epoprostenol in patients with pulmonary arterial hypertension. DESIGN:A 16-week...

journal_title：Annals of internal medicine

authors： Simonneau G,Rubin LJ,Galiè N,Barst RJ,Fleming TR,Frost AE,Engel PJ,Kramer MR,Burgess G,Collings L,Cossons N,Sitbon O,Badesch DB,PACES Study Group.

更新日期：2008-10-21 00:00:00

abstract：DESCRIPTION:Reaffirmation of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for testicular cancer. METHODS:The USPSTF performed a targeted literature search for benefits and harms of screening for testicular cancer in asymptomatic males and found no new studies. RECOMMENDA...

journal_title：Annals of internal medicine

authors： U.S. Preventive Services Task Force.

更新日期：2011-04-05 00:00:00

abstract：Background:Little is known about how physician time is allocated in ambulatory care. Objective:To describe how physician time is spent in ambulatory practice. Design:Quantitative direct observational time and motion study (during office hours) and self-reported diary (after hours). Setting:U.S. ambulatory care in 4 ...

journal_title：Annals of internal medicine

authors： Sinsky C,Colligan L,Li L,Prgomet M,Reynolds S,Goeders L,Westbrook J,Tutty M,Blike G

更新日期：2016-12-06 00:00:00

abstract：:Two patients had recurrent facial edema and peripheral blood eosinophilia. One patient showed a marked increase in the serum level of the eosinophil granule major basic protein. In both patients, skin biopsy samples showed nonspecific mononuclear cell inflammation with few eosinophils. However, immunofluorescence stai...

journal_title：Annals of internal medicine

authors： Songsiridej V,Peters MS,Dor PJ,Ackerman SJ,Gleich GJ,Busse WW

更新日期：1985-10-01 00:00:00

abstract：PURPOSE:To compare the efficacy, safety, and cost-effectiveness of low-molecular-weight heparin with standard heparin for the prevention of deep vein thrombosis after total hip arthroplasty. DATA IDENTIFICATION:Studies were identified by MEDLINE search and review of bibliographies of retrieved articles. Hospital resou...

journal_title：Annals of internal medicine

authors： Anderson DR,O'Brien BJ,Levine MN,Roberts R,Wells PS,Hirsh J

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Because only limited evidence suggests that elastic stockings prevent the post-thrombotic syndrome in patients with symptomatic deep venous thrombosis (DVT), these stockings are not widely used. OBJECTIVE:To evaluate the efficacy of compression elastic stockings for prevention of the post-thrombotic syndrom...

journal_title：Annals of internal medicine

authors： Prandoni P,Lensing AW,Prins MH,Frulla M,Marchiori A,Bernardi E,Tormene D,Mosena L,Pagnan A,Girolami A

更新日期：2004-08-17 00:00:00