Colony-stimulating factors and host defense.

Abstract:

:Colony-stimulating factors are growth factors responsible for the proliferation and the maturation of bone marrow stem cells to fully differentiated granulocytes and monocytes. In addition to their effects on hematopoiesis, some colony-stimulating factors prime mature cells for enhanced chemotaxis, phagocytosis, and killing in response to physiologic stimuli. The action of colony-stimulating factors is mediated by growth factor receptors on precursor and mature effector cells. The results of studies of granulocyte-macrophage colony-stimulating factors in patients with the acquired immunodeficiency syndrome (AIDS) suggest a possible therapeutic role for colony-stimulating factors in augmenting mechanism of host defense.

journal_name

Ann Intern Med

authors

Weisbart RH,Gasson JC,Golde DW

doi

10.7326/0003-4819-110-4-297

subject

Has Abstract

pub_date

1989-02-15 00:00:00

pages

297-303

issue

4

eissn

0003-4819

issn

1539-3704

journal_volume

110

pub_type

临床试验,杂志文章,评审
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    更新日期:1996-12-15 00:00:00

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    journal_title:Annals of internal medicine

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    更新日期:1991-10-01 00:00:00

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    journal_title:Annals of internal medicine

    pub_type: 杂志文章

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    journal_title:Annals of internal medicine

    pub_type: 杂志文章,meta分析,评审

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    更新日期:2004-07-06 00:00:00

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    更新日期:2000-01-04 00:00:00

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    pub_type: 杂志文章

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    更新日期:1986-09-01 00:00:00

  • The association between midlife cardiorespiratory fitness levels and later-life dementia: a cohort study.

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    更新日期:2013-02-05 00:00:00

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    更新日期:2005-01-18 00:00:00

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    更新日期:2009-12-15 00:00:00

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    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章,随机对照试验

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    更新日期:1996-03-15 00:00:00

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    pub_type: 临床试验,杂志文章,评审

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    更新日期:1982-02-01 00:00:00

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    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

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  • Thyroid autoimmunity: increased frequency in relatives of insulin-dependent diabetes patients.

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    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-83-2-170

    authors: Fialkow PJ,Zavala C,Nielsen R

    更新日期:1975-08-01 00:00:00

  • Cisplatin, vinblastine, and bleomycin in advanced and recurrent ovarian germ-cell tumors. A trial of the Gynecologic Oncology Group.

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    journal_title:Annals of internal medicine

    pub_type: 临床试验,杂志文章

    doi:10.7326/0003-4819-111-1-22

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    更新日期:1989-07-01 00:00:00

  • Direct binding studies of adrenergic receptors: biochemical, physiologic, and clinical implications.

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    journal_title:Annals of internal medicine

    pub_type: 杂志文章,评审

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    authors: Lefkowitz RJ

    更新日期:1979-09-01 00:00:00

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    pub_type: 杂志文章,评审

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    更新日期:2003-06-17 00:00:00

  • HemoQuant, a new quantitative assay for fecal hemoglobin. Comparison with Hemoccult.

    abstract::HemoQuant, an assay based on heme-derived porphyrin, quantifies both total fecal hemoglobin ant that fraction already converted to porphyrin by gut flora (the intestinal converted fraction). Recovery by HemoQuant of blood added to stools exceeded 99% and was not affected by ascorbic acid, iron, or other additives. Hem...

    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:10.7326/0003-4819-101-3-297

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    更新日期:1984-09-01 00:00:00

  • Lost in transition: challenges and opportunities for improving the quality of transitional care.

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    journal_title:Annals of internal medicine

    pub_type: 杂志文章

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    更新日期:2004-10-05 00:00:00

  • Monovalent influenza A(H1N1) vaccine, 1986-1987. Recommendations of the Immunization Practices Advisory Committee. Centers for Disease Control, Department of Health and Human Services.

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    journal_title:Annals of internal medicine

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1986-11-01 00:00:00

  • Hypernatremia in elderly patients. A heterogeneous, morbid, and iatrogenic entity.

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  • Screening for Urinary Incontinence in Women: A Recommendation From the Women's Preventive Services Initiative.

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    pub_type: 杂志文章

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    authors: Ganser A,Ottmann OG,Erdmann H,Schulz G,Hoelzer D

    更新日期:1989-12-01 00:00:00