The effect of recombinant human granulocyte-macrophage colony-stimulating factor on neutropenia and related morbidity in chronic severe neutropenia.

abstract：BACKGROUND:Although weight loss improves risk factors for cardiovascular and metabolic disease, it is unclear whether intentional weight loss reduces mortality rates. OBJECTIVE:To examine the relationships among intention to lose weight, weight loss, and all-cause mortality. DESIGN:Prospective cohort study using a pr...

journal_title：Annals of internal medicine

authors： Gregg EW,Gerzoff RB,Thompson TJ,Williamson DF

更新日期：2003-03-04 00:00:00

abstract：BACKGROUND:Sleep-related accidents often involve healthy young persons who are driving at night. Coffee and napping restore alertness, but no study has compared their effects on real nighttime driving performances. OBJECTIVE:To test the effects of 125 mL of coffee (half a cup) containing 200 mg of caffeine, placebo (d...

journal_title：Annals of internal medicine

authors： Philip P,Taillard J,Moore N,Delord S,Valtat C,Sagaspe P,Bioulac B

更新日期：2006-06-06 00:00:00

abstract：:Palliative care prioritizes symptom management and quality of life throughout the course of serious illness. Regardless of whether care is inpatient or outpatient, primary or subspecialty, a solid understanding of the basics of effective communication, symptom management, and end-of-life care is crucial. This article ...

journal_title：Annals of internal medicine

authors： Swetz KM,Kamal AH

更新日期：2018-03-06 00:00:00

abstract：BACKGROUND:The optimal strategy for diagnosis of deep venous thrombosis (DVT) is less well established for the upper extremities than for the lower extremities. Duplex color ultrasonography can be difficult to perform in the upper extremities because of their anatomy, and contrast venography is often indicated. Moreove...

journal_title：Annals of internal medicine

authors： Baarslag HJ,van Beek EJ,Koopman MM,Reekers JA

更新日期：2002-06-18 00:00:00

abstract：:Traditionally, acupuncture is embedded in naturalistic theories that are compatible with Confucianism and Taoism. Such ideas as yin-yang, qi, dampness, and wind represent East Asian conceptual frameworks that emphasize the reliability of ordinary, human sensory awareness. Many physicians who practice acupuncture rejec...

journal_title：Annals of internal medicine

authors： Kaptchuk TJ

更新日期：2002-03-05 00:00:00

abstract：:For over 200 years digitalis compounds have been used to treat atrial fibrillation. The rapid ventricular response to atrial fibrillation is frequently treated with digoxin to produce a controlled heart rate. Digoxin has also been proposed as a treatment for terminating recent-onset atrial fibrillation, for maintainin...

journal_title：Annals of internal medicine

authors： Falk RH,Leavitt JI

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVE:To critically evaluate the evidence for recommending the screening of asymptomatic men for prostate cancer with a blood test to detect a prostate-specific antigen (PSA). DATA SOURCES:Relevant articles on screening for prostate cancer were identified from MEDLINE searches, from the authors' files, and from th...

journal_title：Annals of internal medicine

authors： Kramer BS,Brown ML,Prorok PC,Potosky AL,Gohagan JK

更新日期：1993-11-01 00:00:00

abstract：:Nineteen patients with advanced refractory metastatic breast cancer no longer responsive to chemotherapy were treated in the first phase II efficacy trial of recombinant leukocyte A interferon (IFL-rA), a highly purified single molecular species of alpha interferon prepared by recombinant DNA methods. Patients receive...

journal_title：Annals of internal medicine

authors： Sherwin SA,Mayer D,Ochs JJ,Abrams PG,Knost JA,Foon KA,Fein S,Oldham RK

更新日期：1983-05-01 00:00:00

abstract：:Communication in the delivery of health care services occurs along 2 axes: between providers and patients and among several providers. In primary care, a principle objective in the provider-patient relationship is facilitating whole-person care, which is care provided in the context of family and community. In additio...

journal_title：Annals of internal medicine

authors： Weiner SJ,Barnet B,Cheng TL,Daaleman TP

更新日期：2005-04-19 00:00:00

abstract：:Ambulatory education has become an essential part of all internal medicine residencies. To develop excellent ambulatory education programs, we must thoroughly understand the opportunities available in such a setting, and the leaders in internal medicine must be willing to experiment with nontraditional locations and r...

journal_title：Annals of internal medicine

authors： Schuster BL

更新日期：1992-06-15 00:00:00

abstract：OBJECTIVE:To determine the most effective and safe dose of enoxaparin to prevent deep venous thrombosis in high-risk surgical patients. DESIGN:A double-blind, randomized, multicenter clinical trial. SETTING:Private, university, and government hospitals in the United States. PATIENTS:572 patients having elective hip ...

journal_title：Annals of internal medicine

authors： Spiro TE,Johnson GJ,Christie MJ,Lyons RM,MacFarlane DE,Blasier RB,Tremaine MD

更新日期：1994-07-15 00:00:00

abstract：Background:The safety and effectiveness of dual therapy (direct oral anticoagulant [DOAC] plus P2Y12 inhibitor) versus triple therapy (vitamin K antagonist plus aspirin and P2Y12 inhibitor) in patients with nonvalvular atrial fibrillation (AF) after percutaneous coronary intervention (PCI) is unclear. Purpose:To exami...

journal_title：Annals of internal medicine

authors： Khan SU,Osman M,Khan MU,Khan MS,Zhao D,Mamas MA,Savji N,Al-Abdouh A,Hasan RK,Michos ED

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:Recent postmarketing trials produced conflicting results about the risk for hospitalized heart failure (hHF) associated with dipeptidyl peptidase-4 (DPP-4) inhibitors, creating uncertainty about the safety of these antihyperglycemic agents. OBJECTIVE:To examine the associations of hHF with saxagliptin and s...

journal_title：Annals of internal medicine

authors： Toh S,Hampp C,Reichman ME,Graham DJ,Balakrishnan S,Pucino F,Hamilton J,Lendle S,Iyer A,Rucker M,Pimentel M,Nathwani N,Griffin MR,Brown NJ,Fireman BH

更新日期：2016-06-07 00:00:00

abstract：BACKGROUND:Poor patient attendance to scheduled flexible sigmoidoscopy or colonoscopy may contribute to deficient colorectal cancer screening. OBJECTIVE:To examine the association of physician appointment-keeping behavior with attendance to scheduled endoscopic studies of the colon. DESIGN:Retrospective cohort. SETT...

journal_title：Annals of internal medicine

authors： Turner BJ,Weiner M,Yang C,TenHave T

更新日期：2004-04-06 00:00:00

abstract：:The question of whether initial treatment is necessary in relatively asymptomatic patients with stage III and IV non-Hodgkin's lymphomas of favorable histologic types was studied by retrospective analysis. Two groups of patients were studied: [1] 44 nonprotocol patients, followed since 1963, in whom initial treatment ...

journal_title：Annals of internal medicine

authors： Portlock CS,Rosenberg SA

更新日期：1979-01-01 00:00:00

abstract：:In five patients with hypertension and marked impairment of renal function due to renal artery stenosis in a solitary functioning kidney, a nonsurgical technique, percutaneous transluminal angioplasty, was used to dilate the stenotic renal artery. Blood pressure improved in all five patients, and renal function improv...

journal_title：Annals of internal medicine

authors： Weinberger MH,Yune HY,Grim CE,Luft FC,Klatte EC,Donohue JP

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:Questions remain about the importance of smoking and smoking cessation after incident myocardial infarction. OBJECTIVE:To assess the association between smoking status and risk for recurrent coronary events. DESIGN:Retrospective, population-based, inception cohort study. SETTING:Health maintenance organiz...

journal_title：Annals of internal medicine

authors： Rea TD,Heckbert SR,Kaplan RC,Smith NL,Lemaitre RN,Psaty BM

更新日期：2002-09-17 00:00:00

abstract：:The 1986 False Claims Act Amendments authorize private citizens to sue on behalf of the U.S. government to recover federal funds from fraudulent recipients. The "relator" receives a share of any proceeds from a successful lawsuit. Originally enacted because of defense procurement scandals, this statute also applies to...

journal_title：Annals of internal medicine

authors： Hsia DC

更新日期：1991-06-15 00:00:00

abstract：PURPOSE:To examine the cost-effectiveness of test-treatment strategies for patients suspected of having Lyme disease. DATA SOURCES:The medical literature was searched for information on outcomes and costs. Expert opinion was sought for information on utilities. STUDY SELECTION:Articles that described patient populati...

journal_title：Annals of internal medicine

authors： Nichol G,Dennis DT,Steere AC,Lightfoot R,Wells G,Shea B,Tugwell P

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The number of very elderly persons who are candidates for implantation of a permanent pacemaker is increasing, but the effect of cardiac pacing on long-term survival and functional variables has not been determined. OBJECTIVE:To determine long-term survival after implantation of a permanent pacemaker in oct...

journal_title：Annals of internal medicine

authors： Shen WK,Hayes DL,Hammill SC,Bailey KR,Ballard DJ,Gersh BJ

更新日期：1996-09-15 00:00:00

abstract：STUDY OBJECTIVE:To determine the association between current non-aspirin nonsteroidal anti-inflammatory drug (NSAID) use and fatal peptic ulcers or upper gastrointestinal hemorrhage. DESIGN:Nested case control study using a linked Medicaid-death certificate database. SETTING:Tennessee Medicaid enrollees aged 60 and g...

journal_title：Annals of internal medicine

authors： Griffin MR,Ray WA,Schaffner W

更新日期：1988-09-01 00:00:00

abstract：:Transmission of the human immunodeficiency virus (HIV) was studied in a group of patients with cancer who received transfusion of blood components harvested from a single, asymptomatic, seropositive donor. Of ten living recipients, nine had antibodies to the virus in fresh or cryopreserved sera at a median of 384 days...

journal_title：Annals of internal medicine

authors： Anderson KC,Gorgone BC,Marlink RG,Ferriani R,Essex ME,Benz PM,Groopman JE

更新日期：1986-10-01 00:00:00

abstract：:Because of difficulties in antemortem diagnosis of systemic aspergillosis, a radioimmunoassay to an Aspergillus fumigatus carbohydrate was developed and evaluated in patients with mycotic or bacterial infections. Antigenemia was detected in sera obtained antemortem from four of seven patients with systemic aspergillos...

journal_title：Annals of internal medicine

authors： Weiner MH

更新日期：1980-06-01 00:00:00

abstract：:Sulfasalazine is metabolized by intestinal bacteria, resulting in the release of sulfapyridine and 5-aminosalicylate. The drug is useful in the treatment of active ulcerative colitis as well as in preventing relapses of the disease in remission. Although effective in active Crohn's disease as well, sulfasalazine appea...

journal_title：Annals of internal medicine

authors： Peppercorn MA

更新日期：1984-09-01 00:00:00

abstract：:We tested the relative efficacy of bronchodilators delivered in aerosol and in oral form in 17 patients with asthma in a double-blind randomized sequence. Treatment consisted of a 20-mg tablet of metaproterenol sulfate, five puffs of metaproterenol aerosol (0.65 mg in each puff for a total of 3.25 mg) administered 20 ...

journal_title：Annals of internal medicine

authors： Shim C,Williams MH Jr

更新日期：1980-09-01 00:00:00

abstract：DESCRIPTION:Update of the 2009 U.S. Preventive Services Task Force (USPSTF) recommendation on counseling and interventions to prevent tobacco use and tobacco-related disease in adults, including pregnant women. METHODS:The USPSTF reviewed the evidence on interventions for tobacco smoking cessation that are relevant to...

journal_title：Annals of internal medicine

authors： Siu AL,U.S. Preventive Services Task Force.

更新日期：2015-10-20 00:00:00

abstract：BACKGROUND:Growing evidence indicates that peripheral neuropathy (PN) is common even in the absence of diabetes. However, the clinical sequelae of PN have not been quantified in the general population. OBJECTIVE:To assess the associations of PN with all-cause and cardiovascular mortality in the general adult populatio...

journal_title：Annals of internal medicine

authors： Hicks CW,Wang D,Matsushita K,Windham BG,Selvin E

更新日期：2020-12-08 00:00:00

abstract：:After decades of silence, the German Society for Internal Medicine (DGIM) has made considerable efforts to come to terms with its role and actions during the Nazi era (1933 to 1945). This is particularly important because, with more than 27 000 members, the DGIM is the largest medical society in present-day Germany. S...

journal_title：Annals of internal medicine

authors： Hofer HG,Forsbach R,Fölsch UR

更新日期：2020-09-01 00:00:00

abstract：:A 34-year-old man had polar extremes of B cell dysfunction: systemic lupus erythematosus evolving into common variable hypogammaglobulinemia. He presented in 1974 with seizures and six other criteria for systemic lupus erythematosus; his antinuclear antibody titer was 1:1024 and IgG level, 2870 mg/dL. After 5 months o...

journal_title：Annals of internal medicine

authors： Sussman GL,Rivera VJ,Kohler PF

更新日期：1983-07-01 00:00:00

abstract：:We have seen two patients whose hepatitis was due to the administration of aprindine, a new antiarrhythmic agent. In both patients evidence of hepatitis appeared within 3 weeks of initiating aprindine therapy and resolved rapidly when the drug was withdrawn. The reintroduction of aprindine in one patient was associate...

journal_title：Annals of internal medicine

authors： Herlong HF,Reid PR,Boitnott JK,Maddrey WC

更新日期：1978-09-01 00:00:00