Effectiveness and cost-effectiveness of expanded antiviral prophylaxis and adjuvanted vaccination strategies for an influenza A (H5N1) pandemic.

abstract：BACKGROUND:Clinical trial registries are in widespread use to promote transparency around trials and their results. OBJECTIVE:To describe characteristics of drug trials listed in ClinicalTrials.gov and examine whether the funding source of these trials is associated with favorable published outcomes. DESIGN:An observ...

journal_title：Annals of internal medicine

authors： Bourgeois FT,Murthy S,Mandl KD

更新日期：2010-08-03 00:00:00

abstract：BACKGROUND:Current magnetic resonance techniques generate high signal from venous blood and show thrombi as filling defects. Magnetic resonance direct thrombus imaging (MRDTI) directly visualizes acute thrombus. OBJECTIVE:To determine the accuracy of MRDTI for diagnosis of acute symptomatic deep venous thrombosis (DVT...

journal_title：Annals of internal medicine

authors： Fraser DG,Moody AR,Morgan PS,Martel AL,Davidson I

更新日期：2002-01-15 00:00:00

abstract：:The second National Health and Nutrition Examination Survey found that 26% of U.S. adults, or about 34 million people aged 20 to 75 years, are overweight. The survey used a body mass index of 27.8 kg/m2 or greater for men and 27.3 or greater for women to define overweight. Prevalence of overweight increases with advan...

journal_title：Annals of internal medicine

authors： Van Itallie TB

更新日期：1985-12-01 00:00:00

abstract：:It is hypothesized that peritoneal fluid might be used as an alternative vehicle for monitoring the clinical chemistry of patients on peritoneal dialyses and save these patients the venesection and resultant blood loss. Peritoneal fluid was obtained before 47.2% of 106 dialysis treatments and compared with simultaneou...

journal_title：Annals of internal medicine

authors： Kelton JG,Ulan R,Stiller C,Holmes E

更新日期：1978-07-01 00:00:00

abstract：:In an era of increasing competition in medical care, critical pathway guidelines have emerged as one of the most popular new initiatives intended to reduce costs while maintaining or even improving the quality of care. Developed primarily for high-volume hospital diagnoses, critical pathways display goals for patients...

journal_title：Annals of internal medicine

authors： Pearson SD,Goulart-Fisher D,Lee TH

更新日期：1995-12-15 00:00:00

abstract：STUDY OBJECTIVE:To determine the association between current non-aspirin nonsteroidal anti-inflammatory drug (NSAID) use and fatal peptic ulcers or upper gastrointestinal hemorrhage. DESIGN:Nested case control study using a linked Medicaid-death certificate database. SETTING:Tennessee Medicaid enrollees aged 60 and g...

journal_title：Annals of internal medicine

authors： Griffin MR,Ray WA,Schaffner W

更新日期：1988-09-01 00:00:00

abstract：:Between June 1980 and September 1981 we evaluated 24 cases of endocarditis from methicillin-resistant Staphylococcus aureus. All of the cases occurred in drug addicts and all were community-acquired. The patients ranged in age from 21 to 59 years and represented an older population than that generally reported for bac...

journal_title：Annals of internal medicine

authors： Levine DP,Cushing RD,Jui J,Brown WJ

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:Few treatments for back pain are supported by strong scientific evidence. Conventional treatments, although widely used, have had limited success. Dissatisfied patients have, therefore, turned to complementary and alternative medical therapies and providers for care for back pain. PURPOSE:To provide a rigor...

journal_title：Annals of internal medicine

authors： Cherkin DC,Sherman KJ,Deyo RA,Shekelle PG

更新日期：2003-06-03 00:00:00

abstract：:The traditional exchange of medical expertise between physicians for patient benefit has been accomplished by referral. Physicians have traditionally decided when and to whom to refer patients. Health care "systems" now dominate medical practice, and their formats can alter spontaneous collegial interaction in referra...

journal_title：Annals of internal medicine

authors： Schaffer WA,Holloman FC Jr

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:Many nonpharmacologic therapies are available for treatment of low back pain. PURPOSE:To assess benefits and harms of acupuncture, back schools, psychological therapies, exercise therapy, functional restoration, interdisciplinary therapy, massage, physical therapies (interferential therapy, low-level laser ...

journal_title：Annals of internal medicine

authors： Chou R,Huffman LH,American Pain Society.,American College of Physicians.

更新日期：2007-10-02 00:00:00

abstract：:Antibiotic-associated diarrhea and colitis were well established soon after antibiotics became available. Early work implicated Staphylococcus aureus, but in 1978 Clostridium difficile became the established pathogen in the vast majority of cases. In the first 5 years (1978 through 1983), the most common cause was cli...

journal_title：Annals of internal medicine

authors： Bartlett JG

更新日期：2006-11-21 00:00:00

abstract：:To increase the utility of administrative databases, it has been recommended that they include disease-specific, patient-centered outcome measures. This paper reviews practical and theoretical considerations and the critical evidence to support this recommendation. The strengths and weaknesses of the recommended appro...

journal_title：Annals of internal medicine

authors： Liang MH,Shadick N

更新日期：1997-10-15 00:00:00

abstract：BACKGROUND:Although some studies suggest that access to cardiac procedures may differ by sex, others have found no evidence of gender bias in cardiac care. OBJECTIVE:To study rates of percutaneous coronary intervention (PCI) or coronary artery bypass graft (CABG) surgery in men and women after cardiac catheterization....

journal_title：Annals of internal medicine

authors： Ghali WA,Faris PD,Galbraith PD,Norris CM,Curtis MJ,Saunders LD,Dzavik V,Mitchell LB,Knudtson ML,Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) Investigators.

更新日期：2002-05-21 00:00:00

abstract：BACKGROUND:Observations that risk for colorectal cancer is elevated in patients with inflammatory bowel disease and that long-term use of anti-inflammatory drugs may reduce colorectal cancer risk have raised the possibility that inflammation may play a role in the development of colorectal cancer. While a recent prospe...

journal_title：Annals of internal medicine

authors： Zhang SM,Buring JE,Lee IM,Cook NR,Ridker PM

更新日期：2005-03-15 00:00:00

abstract：:During the past quarter century, general internal medicine has emerged as a vital discipline. In the realm of patient care, it is the integrating discipline par excellence. Ironically, as general internists face the challenge of integrating advances of dizzying speed and complexity, and as their clinical practice beco...

journal_title：Annals of internal medicine

authors： Larson EB

更新日期：2001-05-15 00:00:00

abstract：OBJECTIVE:To evaluate the influence of a human immunodeficiency virus (HIV) vaccine given to uninfected volunteers on the interpretation of serodiagnostic HIV test results. DESIGN:Retrospective cohort study. SETTING:5 AIDS Vaccine Evaluation Units funded by the National Institute of Allergy and Infectious Diseases. ...

journal_title：Annals of internal medicine

authors： Belshe RB,Clements ML,Keefer MC,Graham BS,Corey L,Sposto R,Wescott S,Lawrence D

更新日期：1994-10-15 00:00:00

abstract：BACKGROUND:Antioxidant vitamins are thought to play a role in atherosclerosis. Supplementation of these nutrients has been explored as a means of reducing cardiovascular morbidity and mortality. PURPOSE:To assess the evidence of the effectiveness of vitamin supplementation, specifically vitamins A, C, and E; beta-caro...

journal_title：Annals of internal medicine

authors： Morris CD,Carson S

更新日期：2003-07-01 00:00:00

abstract：:We evaluated bone disease in eight white men between the ages of 49 and 61 years who had been abusing alcohol for at least 10 years. The mean density of vertebral cancellous bone was 58% of normal, whereas the mean density of appendicular cortical bone was 90% of normal. Marked reduction in active bone resorption and ...

journal_title：Annals of internal medicine

authors： Bikle DD,Genant HK,Cann C,Recker RR,Halloran BP,Strewler GJ

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Health care-associated infections from invasive medical devices in the intensive care unit (ICU) are a major threat to patient safety. Most published studies of ICU-acquired infections have come from industrialized western countries. In a Centers for Disease Control and Prevention (CDC) National Nosocomial I...

journal_title：Annals of internal medicine

authors： Rosenthal VD,Maki DG,Salomao R,Moreno CA,Mehta Y,Higuera F,Cuellar LE,Arikan OA,Abouqal R,Leblebicioglu H,International Nosocomial Infection Control Consortium.

更新日期：2006-10-17 00:00:00

abstract：BACKGROUND:Liver transplantation holds promise as a treatment for familial amyloid polyneuropathy. OBJECTIVE:To determine whether peripheral nerves regenerate in patients with familial amyloid polyneuropathy after liver transplantation. DESIGN:Case report. SETTING:University hospital in Matsumoto, Japan. PATIENT:A ...

journal_title：Annals of internal medicine

authors： Ikeda S,Takei Y,Yanagisawa N,Matsunami H,Hashikura Y,Ikegami T,Kawasaki S

更新日期：1997-10-15 00:00:00

abstract：BACKGROUND:Menopausal hormone therapy to prevent chronic conditions is currently not recommended because of its adverse effects. PURPOSE:To update evidence about the effectiveness of hormone therapy in reducing risk for chronic conditions and adverse effects, and to examine whether outcomes vary among women in differe...

journal_title：Annals of internal medicine

authors： Nelson HD,Walker M,Zakher B,Mitchell J

更新日期：2012-07-17 00:00:00

abstract：:Relapsing polychondritis, an uncommon, chronic, multisystem disorder characterized by recurrent episodes of inflammation of cartilaginous tissues, can be life-threatening, debilitating, and difficult to diagnose. This review is based on the authors' experience with 36 patients with relapsing polychondritis who were fo...

journal_title：Annals of internal medicine

authors： Trentham DE,Le CH

更新日期：1998-07-15 00:00:00

abstract：:Congenital adrenal hyperplasia describes a group of inherited autosomal recessive disorders characterized by an enzymatic defect in cortisol biosynthesis, compensatory increases in corticotropin secretion, and adrenocortical hyperplasia. 21-Hydroxylase deficiency is responsible for more than 95% of cases and is one of...

journal_title：Annals of internal medicine

authors： Merke DP,Bornstein SR,Avila NA,Chrousos GP

更新日期：2002-02-19 00:00:00

abstract：:Position statements opposing legalization of physician-assisted suicide by organizations such as the American College of Physicians-American Society of Internal Medicine rightly emphasize that palliative care should be the standard of care for the dying, and that the inadequacies that exist in its delivery should be r...

journal_title：Annals of internal medicine

authors： Quill TE,Cassel CK

更新日期：2003-02-04 00:00:00

abstract：:Reversible cerebral vasoconstriction syndromes (RCVS) comprise a group of diverse conditions, all characterized by reversible multifocal narrowing of the cerebral arteries heralded by sudden (thunderclap), severe headaches with or without associated neurologic deficits. Reversible cerebral vasoconstriction syndromes a...

journal_title：Annals of internal medicine

authors： Calabrese LH,Dodick DW,Schwedt TJ,Singhal AB

更新日期：2007-01-02 00:00:00

abstract：:Impairment of penicillin G excretion in renal failure may result in life-threatening, dose-related toxicity. We report a method for achieving a desired mean serum penicillin G concentration in patients with renal failure, with minimal risk of both undertreatment and drug toxicity. The method is based on the linear rel...

journal_title：Annals of internal medicine

authors： Bryan CS,Stone WJ

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Castleman disease, an unusual condition of unknown cause consisting of a massive proliferation of lymphoid tissue, remains a clinicopathologic diagnosis. Three histologic variants (hyaline vascular, plasma-cell, and mixed) and two clinical types (localized and multicentric) of Castleman disease have been des...

journal_title：Annals of internal medicine

authors： Herrada J,Cabanillas F,Rice L,Manning J,Pugh W

更新日期：1998-04-15 00:00:00

abstract：BACKGROUND:Advice and exercise are widely recommended for subacute low back pain, but the effectiveness of these interventions is unclear. OBJECTIVE:To investigate the effectiveness of physiotherapist-prescribed exercise, advice, or both for subacute low back pain. DESIGN:Factorial randomized, placebo-controlled tria...

journal_title：Annals of internal medicine

authors： Pengel LH,Refshauge KM,Maher CG,Nicholas MK,Herbert RD,McNair P

更新日期：2007-06-05 00:00:00

abstract：STUDY OBJECTIVE:To assess respiratory muscle fatigue in acute respiratory failure in patients with chronic obstructive pulmonary disease and evaluate its influence on weaning patients from mechanical ventilation. DESIGN AND PATIENTS:We studied the time course of tracheal occlusion pressure (P0.1) and high-to-low ratio...

journal_title：Annals of internal medicine

authors： Murciano D,Boczkowski J,Lecocguic Y,Emili JM,Pariente R,Aubier M

更新日期：1988-06-01 00:00:00

abstract：:Opioid dependence is a chronic relapsing medical condition with substantial health and societal complications. Recent federal initiatives are designed to enhance the medical treatment of patients with opioid dependence and will expand the role of internists in the care of these patients. These initiatives include a pr...

journal_title：Annals of internal medicine

authors： Fiellin DA,O'Connor PG

更新日期：2002-10-15 00:00:00