The toxicity of D-penicillamine in systemic sclerosis.

abstract：:Thirty-five consecutive patients with progressive systemic sclerosis were prospectively evaluated for evidence of Sjögren's syndrome. Six of the 35 (17%) were judged to have the disorder. This is a higher prevalence than in most reports, but much lower than that recently reportedly by Alarcón-Segovia and associates (7...

journal_title：Annals of internal medicine

authors： Cipoletti JF,Buckingham RB,Barnes EL,Peel RL,Mahmood K,Cignetti FE,Pierce JM,Rabin BS,Rodnan GP

更新日期：1977-11-01 00:00:00

abstract：Background:Probiotics, prebiotics, and synbiotics are used increasingly, although the safety and potential harms of these interventions are poorly understood. Purpose:To examine how harms-related information is reported in publications of randomized controlled trials (RCTs) of probiotics, prebiotics, and synbiotics. ...

journal_title：Annals of internal medicine

authors： Bafeta A,Koh M,Riveros C,Ravaud P

更新日期：2018-08-21 00:00:00

abstract：OBJECTIVE:To determine whether self-assessment of purified protein derivative of tuberculin (PPD) skin test reactions, done using a simple two-choice approach, is an effective screening method for tuberculosis. DESIGN:Double-blind comparison between self-assessments and trained professional readings of PPD skin test r...

journal_title：Annals of internal medicine

authors： Prezant DJ,Kelly KJ,Karwa ML,Kavanagh K

更新日期：1996-08-15 00:00:00

abstract：:Cataract disrupts the crystalline lens, a transparent, elastic, avascular, biconvex structure composed of a capsule, lens epithelium, and lens fiber cells. Many factors contribute to the progression of lens opacity, but aging is most frequently associated with cataract. As aging-related cataract develops, many biochem...

journal_title：Annals of internal medicine

authors： Straatsma BR,Foos RY,Horwitz J,Gardner KM,Pettit TH

更新日期：1985-01-01 00:00:00

abstract：:Seventy homosexual men with unexplained persistent diffuse lymphadenopathy enrolled in a prospective natural history study from November 1981 to November 1982. These men had demographic, clinical, and laboratory findings similar to those of homosexual patients with the acquired immunodeficiency syndrome. Pathologic ex...

journal_title：Annals of internal medicine

authors： Abrams DI,Lewis BJ,Beckstead JH,Casavant CA,Drew WL

更新日期：1984-06-01 00:00:00

abstract：:Tax incentives can provide a large financial impetus to change behavior. Current U.S. law establishes a substantial discontinuity in the amount of estate tax that many patients will have to pay in 2010: During this year only, the tax rate drops to zero. This article discusses concerns regarding the sharp change in tax...

journal_title：Annals of internal medicine

authors： Mendenhall GS

更新日期：2008-12-02 00:00:00

abstract：:In a prospective study, mortality ratios were computed in relation to overweight, cancer, and other diseases. The study included 750 000 men and women followed for 12 years. Each person was given a weight index. Death rates for overweight and underweight persons were compared with rates for persons of average weight. ...

journal_title：Annals of internal medicine

authors： Garfinkel L

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVE:To determine in female tennis and squash players the effect of biological age (that is, the starting age of playing relative to the age at menarche) at which tennis or squash playing was started on the difference in bone mineral content between the playing and non-playing arms. DESIGN:Cross-sectional study. ...

journal_title：Annals of internal medicine

authors： Kannus P,Haapasalo H,Sankelo M,Sievänen H,Pasanen M,Heinonen A,Oja P,Vuori I

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:The appropriate duration of therapy for catheter-associated Staphylococcus aureus bacteremia is controversial. Conventional practice dictates that all patients receive prolonged courses of intravenous antibiotics. Some clinicians recommend abbreviated therapeutic courses, but an alternate approach involves p...

journal_title：Annals of internal medicine

authors： Rosen AB,Fowler VG Jr,Corey GR,Downs SM,Biddle AK,Li J,Jollis JG

更新日期：1999-05-18 00:00:00

abstract：:During a 4.4-year period, nonspecific interstitial pneumonitis was seen in 41 of 110 (38%) patients with the acquired immunodeficiency syndrome and accounted for 32% (48/152) of all episodes of clinical pneumonitis. Diffuse alveolar damage was typically a feature of nonspecific interstitial pneumonitis, but neither lu...

journal_title：Annals of internal medicine

authors： Suffredini AF,Ognibene FP,Lack EE,Simmons JT,Brenner M,Gill VJ,Lane HC,Fauci AS,Parrillo JE,Masur H

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:HIV-1 genotypic and phenotypic susceptibility testing (GPT) optimizes antiretroviral selection, but its effect on survival is unknown. OBJECTIVE:To evaluate the association between GPT and survival. DESIGN:Cohort study. SETTING:10 U.S. HIV clinics. PATIENTS:2699 HIV-infected patients eligible for GPT (pl...

journal_title：Annals of internal medicine

authors： Palella FJ Jr,Armon C,Buchacz K,Cole SR,Chmiel JS,Novak RM,Wood K,Moorman AC,Brooks JT,HOPS (HIV Outpatient Study) Investigators.

更新日期：2009-07-21 00:00:00

abstract：:The relation of menopause to cardiovascular disease incidence was examined in women less than 55 years old from the cohort of 2873 women in the initial Framingham examination. Although the number of person-years of experience during the 20 years of observation was nearly the same for premenopausal and postmenopausal s...

journal_title：Annals of internal medicine

authors： Kannel WB,Hjortland MC,McNamara PM,Gordon T

更新日期：1976-10-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of pharmacologic agents for the irritable bowel syndrome. DATA SOURCES:Electronic literature search of MEDLINE (1966 to 1999), EMBASE (1980 to 1999), PsycINFO (1967 to 1999), and the Cochrane controlled trials registry and a manual search of references from bibliographies of identified...

journal_title：Annals of internal medicine

authors： Jailwala J,Imperiale TF,Kroenke K

更新日期：2000-07-18 00:00:00

abstract：OBJECTIVE:To evaluate the relation between skeletal muscle disease (myopathy) and degenerative changes in cardiac muscle (cardiomyopathy) in patients with chronic alcoholism. DESIGN:A cross-sectional study. SETTING:University medical center. PARTICIPANTS:Group A included 24 patients with chronic alcoholism who had d...

journal_title：Annals of internal medicine

authors： Fernandez-Sola J,Estruch R,Grau JM,Pare JC,Rubin E,Urbano-Marquez A

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Variants in genes involved in warfarin metabolism and sensitivity affect individual warfarin requirements and the risk for bleeding. Testing for these variant alleles might allow more personalized dosing of warfarin during the induction phase. In 2007, the U.S. Food and Drug Administration changed the labeli...

journal_title：Annals of internal medicine

authors： Eckman MH,Rosand J,Greenberg SM,Gage BF

更新日期：2009-01-20 00:00:00

abstract：BACKGROUND:Progress of diabetes care is a subject of public health concern. OBJECTIVE:To assess changes in quality of diabetes care in the United States by using standardized measures. DESIGN:National population-based, serial cross-sectional surveys. SETTING:National Health and Nutrition Examination Survey (1988-199...

journal_title：Annals of internal medicine

authors： Saaddine JB,Cadwell B,Gregg EW,Engelgau MM,Vinicor F,Imperatore G,Narayan KM

更新日期：2006-04-04 00:00:00

abstract：:Colony-stimulating factors are growth factors responsible for the proliferation and the maturation of bone marrow stem cells to fully differentiated granulocytes and monocytes. In addition to their effects on hematopoiesis, some colony-stimulating factors prime mature cells for enhanced chemotaxis, phagocytosis, and k...

journal_title：Annals of internal medicine

authors： Weisbart RH,Gasson JC,Golde DW

更新日期：1989-02-15 00:00:00

abstract：:Hypophosphatemic osteomalacia that remits after resection of a coexisting tumor has been described in 35 patients. Because the associated neoplasms have been of mesenchymal origin, it has been inferred that this tumor-induced osteomalacia syndrome is uniquely related to tumours of this derivation. However, in the pres...

journal_title：Annals of internal medicine

authors： Lyles KW,Berry WR,Haussler M,Harrelson JM,Drezner MK

更新日期：1980-08-01 00:00:00

abstract：:Polysaccharide vaccines against diseases caused by Neisseria meningitidis serogroups A and C meningococci are now licensed in the United States. They are prepared as monovalent and as bivalent antigens. This statement summarizes available information on these antigen and offers guidance regarding their role in the con...

journal_title：Annals of internal medicine

authors：

更新日期：1976-02-01 00:00:00

abstract：:Recent data indicate that the lymphadenopathy-associated virus (LAV) is morphologically similar to animal lentiviruses, such as equine infectious anemia and visna viruses. This finding, together with the cross-reactivity of the core proteins of LAV with those of the equine infectious anemia virus and a similarity in g...

journal_title：Annals of internal medicine

authors： Montagnier L

更新日期：1985-11-01 00:00:00

abstract：:This issue provides a clinical overview of sickle cell disease focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits. Only ACP members and individual subscribers can access the electronic features of In the Clinic. No...

journal_title：Annals of internal medicine

authors： Steinberg MH

更新日期：2011-09-06 00:00:00

abstract：:Thirty-two studies (2889 subjects) that investigated the prevalence of the causes of dementia were critically reviewed. Particular attention was paid to potential and actual reversibility. Although dementia manifests itself primarily in old age (particularly age 75 and older), the mean age of patients for the studies ...

journal_title：Annals of internal medicine

authors： Clarfield AM

更新日期：1988-09-15 00:00:00

abstract：BACKGROUND:The number of very elderly persons who are candidates for implantation of a permanent pacemaker is increasing, but the effect of cardiac pacing on long-term survival and functional variables has not been determined. OBJECTIVE:To determine long-term survival after implantation of a permanent pacemaker in oct...

journal_title：Annals of internal medicine

authors： Shen WK,Hayes DL,Hammill SC,Bailey KR,Ballard DJ,Gersh BJ

更新日期：1996-09-15 00:00:00

abstract：:Cost-effectiveness analysis and other forms of decision analysis are becoming more common in the medical literature and are increasingly influential in the development of health policy. Nevertheless, many clinicians find it difficult to apply policies developed from these analyses to individual encounters with patient...

journal_title：Annals of internal medicine

authors： Asch DA,Hershey JC

更新日期：1995-06-01 00:00:00

abstract：:It is hypothesized that peritoneal fluid might be used as an alternative vehicle for monitoring the clinical chemistry of patients on peritoneal dialyses and save these patients the venesection and resultant blood loss. Peritoneal fluid was obtained before 47.2% of 106 dialysis treatments and compared with simultaneou...

journal_title：Annals of internal medicine

authors： Kelton JG,Ulan R,Stiller C,Holmes E

更新日期：1978-07-01 00:00:00

abstract：BACKGROUND:The current standard initial therapies for deep venous thrombosis are low-molecular-weight heparin and unfractionated heparin. In a dose-ranging study of patients with symptomatic deep venous thrombosis, fondaparinux had efficacy and a safety profile similar to those of low-molecular-weight heparin (daltepar...

journal_title：Annals of internal medicine

authors： Büller HR,Davidson BL,Decousus H,Gallus A,Gent M,Piovella F,Prins MH,Raskob G,Segers AE,Cariou R,Leeuwenkamp O,Lensing AW,Matisse Investigators.

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Timely diagnosis of influenza can help clinical management. PURPOSE:To examine the accuracy of rapid influenza diagnostic tests (RIDTs) in adults and children with influenza-like illness and evaluate factors associated with higher accuracy. DATA SOURCES:PubMed and EMBASE through December 2011; BIOSIS and W...

journal_title：Annals of internal medicine

authors： Chartrand C,Leeflang MM,Minion J,Brewer T,Pai M

更新日期：2012-04-03 00:00:00

abstract：OBJECTIVE:To provide a rational strategy for the evaluation and long-term management of epilepsy. DATA SOURCES:Articles written between 1964 and 1993, obtained from a MEDLINE search on epilepsy-related topics as well as from the author's personal files, major reference books on antiepileptic drugs, and references iden...

journal_title：Annals of internal medicine

authors： French J

更新日期：1994-03-01 00:00:00

abstract：:Two patients with profound decrease of alpha1-antitrypsin (PiZZ) presented with severe pannicultis (Weber-Christian disease); one had systemic panniculitis including pancreatitis. Another possible case is quoted from the literature. Although milder forms of panniculitis can have normal Pi phenotypes and alpha1-antitry...

journal_title：Annals of internal medicine

authors： Rubinstein HM,Jaffer AM,Kudrna JC,Lertratanakul Y,Chandrasekhar AJ,Slater D,Schmid FR

更新日期：1977-06-01 00:00:00

abstract：OBJECTIVE:To determine whether a statistical association exists between "low-count" bacteriuria (> 10(2) to 10(4) colony-forming units/mL) and acute urinary symptoms in young women. DESIGN:Prospective, case-control study. SETTING:Gynecology clinic at a student health center. PATIENTS:Women with or without urinary or...

journal_title：Annals of internal medicine

authors： Kunin CM,White LV,Hua TH

更新日期：1993-09-15 00:00:00