Meningococcal polysaccharide vaccines. Recommendation of the Public Health Service Advisory Committee on Immunization Practices, Center for Disease Control, United States Department of Health, Education, and Welfare, Atlanta, Georgia.

abstract：Background:Triplex vaccine was developed to enhance cytomegalovirus (CMV)-specific T cells and prevent CMV reactivation early after hematopoietic stem cell transplant (HCT). Objective:To determine the safety and efficacy of Triplex. Design:First-in-patient, phase 2 trial. (ClinicalTrials.gov: NCT02506933). Setting:3...

journal_title：Annals of internal medicine

authors： Aldoss I,La Rosa C,Baden LR,Longmate J,Ariza-Heredia EJ,Rida WN,Lingaraju CR,Zhou Q,Martinez J,Kaltcheva T,Dagis A,Hardwick N,Issa NC,Farol L,Nademanee A,Al Malki MM,Forman S,Nakamura R,Diamond DJ,TRIPLEX VACCINE St

更新日期：2020-03-03 00:00:00

abstract：PURPOSE:Chemoprevention offers promise as a strategy for reducing morbidity and mortality from breast cancer in women. This review examined the evidence for the effectiveness of chemoprevention in women without a history of breast cancer. DATA SOURCES:MEDLINE (1966 to December 2001). STUDY SELECTION:English-language,...

journal_title：Annals of internal medicine

authors： Kinsinger LS,Harris R,Woolf SH,Sox HC,Lohr KN

更新日期：2002-07-02 00:00:00

abstract：:A platelet transfusion from a blood group O donor, immunized 1 month before with Pneumovax, caused a hemolytic reaction in a blood group A recipient. Forty-five of 59 group O donors (76%) and all of nine group B donors immunized with Pneumovax had a fourfold or higher anti-A response. Half of the anti-A antibody in hi...

journal_title：Annals of internal medicine

authors： Siber GR,Ambrosino DM,Gorgone BC

更新日期：1982-05-01 00:00:00

abstract：:This article applies major economic concepts, such as supply, demand, monopoly, monopsony, adverse selection, and moral hazard, to central features of U.S. health care. These illustrations help explain some of the principal problems of health policy-high cost and the uninsured-and why solutions are difficult to obtain...

journal_title：Annals of internal medicine

authors： Fuchs VR

更新日期：2015-03-03 00:00:00

abstract：BACKGROUND:The pandemic potential of influenza A (H5N1) virus is a prominent public health concern of the 21st century. OBJECTIVE:To estimate the effectiveness and cost-effectiveness of alternative pandemic (H5N1) mitigation and response strategies. DESIGN:Compartmental epidemic model in conjunction with a Markov mod...

journal_title：Annals of internal medicine

authors： Khazeni N,Hutton DW,Garber AM,Owens DK

更新日期：2009-12-15 00:00:00

abstract：STUDY OBJECTIVE:To assess the value of a history and physical examination findings in diagnosing the carpal tunnel syndrome, and to determine whether constellations of clinical findings identify patients at high or low risk for the carpal tunnel syndrome. DESIGN:Comparison of diagnostic tests with neurophysiologic tes...

journal_title：Annals of internal medicine

authors： Katz JN,Larson MG,Sabra A,Krarup C,Stirrat CR,Sethi R,Eaton HM,Fossel AH,Liang MH

更新日期：1990-03-01 00:00:00

abstract：:Despite some impressive recent gains, improving the glaring deficiencies in health care quality is proving to be very hard. Improvement is local, rather than system-wide, and is sustained with difficulty, rather than becoming an intrinsic feature of care. My right knee will probably need to be replaced soon. This has ...

journal_title：Annals of internal medicine

authors： Berwick DM

更新日期：2005-01-18 00:00:00

abstract：STUDY OBJECTIVE:To determine the efficacy of the addition of ifosfamide to cisplatin plus etoposide (VIP), or vinblastine (VeIP), in patients with recurrent germ cell tumors. DESIGN:Nonrandomized, prospective phase II trial. SETTING:Tertiary referral university hospital. PATIENTS:Fifty-six of fifty-eight entered pat...

journal_title：Annals of internal medicine

authors： Loehrer PJ Sr,Lauer R,Roth BJ,Williams SD,Kalasinski LA,Einhorn LH

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVE:To compare inhaled pentamidine with intravenous pentamidine for the treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome (AIDS). DESIGN:A randomized trial. SETTING:Community teaching hospital and hospital-based outpatient treatment center. PATIENTS:Twenty-one homosexual men...

journal_title：Annals of internal medicine

authors： Soo Hoo GW,Mohsenifar Z,Meyer RD

更新日期：1990-08-01 00:00:00

abstract：:Quality improvement (QI) activities can improve health care but must be conducted ethically. The Hastings Center convened leaders and scholars to address ethical requirements for QI and their relationship to regulations protecting human subjects of research. The group defined QI as systematic, data-guided activities d...

journal_title：Annals of internal medicine

authors： Lynn J,Baily MA,Bottrell M,Jennings B,Levine RJ,Davidoff F,Casarett D,Corrigan J,Fox E,Wynia MK,Agich GJ,O'Kane M,Speroff T,Schyve P,Batalden P,Tunis S,Berlinger N,Cronenwett L,Fitzmaurice JM,Dubler NN,James B

更新日期：2007-05-01 00:00:00

abstract：:With the renewed interest in esophageal motility disorders, diffuse esophageal spasm is being diagnosed more frequently. In many clinical settings, however, the term is used as a synonym for noncardiac chest pain. Our review of the literature and broad clinical experience in studying the motility patterns of healthy s...

journal_title：Annals of internal medicine

authors： Richter JE,Castell DO

更新日期：1984-02-01 00:00:00

abstract：STUDY OBJECTIVE:To determine whether obesity preceded knee osteoarthritis and was thus a possible cause. DESIGN:Cohort study with weight and other important variables measured in 1948 to 1951 (mean age of subjects, 37 years) and knee arthritis evaluated in 1983 to 1985 (mean age of subjects, 73 years). SETTING:Popula...

journal_title：Annals of internal medicine

authors： Felson DT,Anderson JJ,Naimark A,Walker AM,Meenan RF

更新日期：1988-07-01 00:00:00

abstract：:The microorganisms that regularly infect patients with the acquired immunodeficiency syndrome (AIDS) have become well recognized. Most take advantage of defects in T-lymphocyte function, but others, such as Streptococcus pneumoniae and Haemophilus influenzae, take advantage of B-cell defects. Still others, such as Sta...

journal_title：Annals of internal medicine

authors： Armstrong D,Gold JW,Dryjanski J,Whimbey E,Polsky B,Hawkins C,Brown AE,Bernard E,Kiehn TE

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:An effective national biosurveillance system expedites outbreak recognition and facilitates response coordination at the federal, state, and local levels. The BioSense system, used at the Centers for Disease Control and Prevention, incorporates chief complaints but not data from the whole encounter note into...

journal_title：Annals of internal medicine

authors： Elkin PL,Froehling DA,Wahner-Roedler DL,Brown SH,Bailey KR

更新日期：2012-01-03 00:00:00

abstract：:Ensuring patient safety is essential for better health care, but preoccupation with niches of medicine, such as patient safety, can inadvertently compromise outcomes if it distracts from other problems that pose a greater threat to health. The greatest benefit for the population comes from a comprehensive view of popu...

journal_title：Annals of internal medicine

authors： Woolf SH

更新日期：2004-01-06 00:00:00

abstract：:The presence of a low anion gap in patients with multiple myeloma has recently been emphasized. This has been related to the retention of chloride and bicarbonate anions to offset the cationic charge of the monoclonal immunoglobulins. We now report the presence of a low anion gap in 50 patients with asymptomatic plasm...

journal_title：Annals of internal medicine

authors： Schnur MJ,Appel GB,Karp G,Osserman EP

更新日期：1977-03-01 00:00:00

abstract：:The term functional somatic syndrome has been applied to several related syndromes characterized more by symptoms, suffering, and disability than by consistently demonstrable tissue abnormality. These syndromes include multiple chemical sensitivity, the sick building syndrome, repetition stress injury, the side effect...

journal_title：Annals of internal medicine

authors： Barsky AJ,Borus JF

更新日期：1999-06-01 00:00:00

abstract：:Behavioral economics provides insights about the development of effective incentives for physicians to deliver high-value care. It suggests that the structure and delivery of incentives can shape behavior, as can thoughtful design of the decision-making environment. This article discusses several principles of behavio...

journal_title：Annals of internal medicine

authors： Emanuel EJ,Ubel PA,Kessler JB,Meyer G,Muller RW,Navathe AS,Patel P,Pearl R,Rosenthal MB,Sacks L,Sen AP,Sherman P,Volpp KG

更新日期：2016-01-19 00:00:00

abstract：BACKGROUND:Hypertension often persists after adrenalectomy for primary aldosteronism. OBJECTIVE:To determine factors associated with resolution of hypertension after adrenalectomy for primary aldosteronism. DESIGN:Retrospective cohort study. SETTING:Tertiary care referral center in Rochester, Minnesota. PATIENTS:Al...

journal_title：Annals of internal medicine

authors： Sawka AM,Young WF,Thompson GB,Grant CS,Farley DR,Leibson C,van Heerden JA

更新日期：2001-08-21 00:00:00

abstract：:Two-dimensional echocardiograms were done during rest and after exercise in 95 patients who subsequently had coronary arteriography. Prior myocardial infarction was present in 36 patients, 35 of whom had wall motion abnormalities. There was no evidence of prior infarction in 59 patients, 44 of whom had coronary diseas...

journal_title：Annals of internal medicine

authors： Armstrong WF,O'Donnell J,Dillon JC,McHenry PL,Morris SN,Feigenbaum H

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:Magnetic resonance imaging (MRI) is avoided in most patients with implanted cardiac devices because of safety concerns. OBJECTIVE:To define the safety of a protocol for MRI at the commonly used magnetic strength of 1.5 T in patients with implanted cardiac devices. DESIGN:Prospective nonrandomized trial. (C...

journal_title：Annals of internal medicine

authors： Nazarian S,Hansford R,Roguin A,Goldsher D,Zviman MM,Lardo AC,Caffo BS,Frick KD,Kraut MA,Kamel IR,Calkins H,Berger RD,Bluemke DA,Halperin HR

更新日期：2011-10-04 00:00:00

abstract：:A 45-year-old woman from Mendoza, Argentina, was severely bitten by a dog that died 4 days later. Before death, the dog was nervous, aggressive, and had occasional seizures. Ten days after the woman had been bitten, rabies vaccine treatment was begun: 14 daily doses of suckling mouse brain vaccine followed by 2 booste...

journal_title：Annals of internal medicine

authors： Porras C,Barboza JJ,Fuenzalida E,Adaros HL,Oviedo AM,Furst J

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Women treated with therapeutic chest radiation may develop breast cancer. PURPOSE:To summarize breast cancer risk and breast cancer surveillance in women after chest radiation for pediatric or young adult cancer. DATA SOURCES:Studies from MEDLINE, EMBASE, the Cochrane Library, and CINAHL (1966 to December ...

journal_title：Annals of internal medicine

authors： Henderson TO,Amsterdam A,Bhatia S,Hudson MM,Meadows AT,Neglia JP,Diller LR,Constine LS,Smith RA,Mahoney MC,Morris EA,Montgomery LL,Landier W,Smith SM,Robison LL,Oeffinger KC

更新日期：2010-04-06 00:00:00

abstract：BACKGROUND:An outbreak of seven cases (in six patients and one health care worker, all of whom had AIDS) of multidrug-resistant tuberculosis occurred in a hospital in Chicago. The hospital had a respirator-fit testing program but no acid-fast bacilli isolation rooms. OBJECTIVE:To identify risk factors for transmission...

journal_title：Annals of internal medicine

authors： Kenyon TA,Ridzon R,Luskin-Hawk R,Schultz C,Paul WS,Valway SE,Onorato IM,Castro K

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Vertebral fractures are a hallmark of postmenopausal osteoporosis and an important end point in trials of osteoporosis treatment, but the clinical significance of these fractures remains uncertain. OBJECTIVE:To determine the association of new vertebral fractures with back pain and back-related functional l...

journal_title：Annals of internal medicine

authors： Nevitt MC,Ettinger B,Black DM,Stone K,Jamal SA,Ensrud K,Segal M,Genant HK,Cummings SR

更新日期：1998-05-15 00:00:00

abstract：:Treatment selection markers, sometimes called predictive markers, are factors that help clinicians select therapies that maximize good outcomes and minimize adverse outcomes for patients. Existing statistical methods for evaluating a treatment selection marker include assessing its prognostic value, evaluating treatme...

journal_title：Annals of internal medicine

authors： Janes H,Pepe MS,Bossuyt PM,Barlow WE

更新日期：2011-02-15 00:00:00

abstract：:Between June 1980 and September 1981 we evaluated 24 cases of endocarditis from methicillin-resistant Staphylococcus aureus. All of the cases occurred in drug addicts and all were community-acquired. The patients ranged in age from 21 to 59 years and represented an older population than that generally reported for bac...

journal_title：Annals of internal medicine

authors： Levine DP,Cushing RD,Jui J,Brown WJ

更新日期：1982-09-01 00:00:00

abstract：:Although many manifestations of giant cell arteries are increasingly recognized, little attention has been paid to respiratory symptoms associated with this disorder. We report the cases of 16 patients with giant cell arteritis who had prominent symptoms related to the respiratory tract including cough, sore throat, a...

journal_title：Annals of internal medicine

authors： Larson TS,Hall S,Hepper NG,Hunder GG

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Severe aplastic anemia is a life-threatening bone marrow failure disorder. High-dose cyclophosphamide therapy followed by allogeneic bone marrow transplantation cures the disease. However, it requires a suitable donor and carries the risk for graft-versus-host disease. A small pilot study demonstrated that h...

journal_title：Annals of internal medicine

authors： Brodsky RA,Sensenbrenner LL,Smith BD,Dorr D,Seaman PJ,Lee SM,Karp JE,Brodsky I,Jones RJ

更新日期：2001-10-02 00:00:00

abstract：:Physical symptoms account for more than half of all outpatient visits, but the specific causes and treatments of many common symptoms are frequently not well established. Because clinical research has primarily targeted specific diseases, symptoms-based research is still an emerging field of scientific inquiry, and op...

journal_title：Annals of internal medicine

authors： Kroenke K

更新日期：2001-05-01 00:00:00