Challenges in systematic reviews: synthesis of topics related to the delivery, organization, and financing of health care.

abstract：:Although thyroid nodules are common, few are malignant and require surgical treatment. A systematic approach to their evaluation is important to avoid unnecessary surgery. Fine-needle aspiration biopsy has resulted in substantial improvements in diagnostic accuracy, cost reductions, and higher malignancy yield at time...

journal_title：Annals of internal medicine

authors： Castro MR,Gharib H

更新日期：2005-06-07 00:00:00

abstract：BACKGROUND:No effective oral therapy exists for early coronavirus disease 2019 (COVID-19). OBJECTIVE:To investigate whether hydroxychloroquine could reduce COVID-19 severity in adult outpatients. DESIGN:Randomized, double-blind, placebo-controlled trial conducted from 22 March through 20 May 2020. (ClinicalTrials.gov...

journal_title：Annals of internal medicine

authors： Skipper CP,Pastick KA,Engen NW,Bangdiwala AS,Abassi M,Lofgren SM,Williams DA,Okafor EC,Pullen MF,Nicol MR,Nascene AA,Hullsiek KH,Cheng MP,Luke D,Lother SA,MacKenzie LJ,Drobot G,Kelly LE,Schwartz IS,Zarychanski R,M

更新日期：2020-10-20 00:00:00

abstract：:Prothrombin complex concentrates are used in the treatment of the congenital bleeding disorders associated with Factors II, VII, IX, and X deficiencies. They have also been extensively used to treat acquired coagulation abnormalities secondary to vitamin K deficiency, warfarin ingestion, and various types of liver dis...

journal_title：Annals of internal medicine

authors： Cederbaum AI,Blatt PM,Roberts HR

更新日期：1976-06-01 00:00:00

abstract：:Endomyocardial biopsy was done 119 times in 98 patients receiving doxorubicin therapy once every 3 weeks and 41 times in 27 patients receiving doxorubicin therapy weekly. Factors contributing to the degree of anthracycline-induced endomyocardial injury were evaluated. Neither age, sex, type of malignancy, concomitant ...

journal_title：Annals of internal medicine

authors： Torti FM,Bristow MR,Howes AE,Aston D,Stockdale FE,Carter SK,Kohler M,Brown BW Jr,Billingham ME

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Radiation therapy is one of many treatment options for patients with prostate cancer. PURPOSE:To update findings on the clinical and biochemical outcomes of radiation therapies for localized prostate cancer. DATA SOURCES:MEDLINE (2007 through March 2011) and the Cochrane Central Register of Controlled Tria...

journal_title：Annals of internal medicine

authors： Bannuru RR,Dvorak T,Obadan N,Yu WW,Patel K,Chung M,Ip S

更新日期：2011-08-02 00:00:00

abstract：DESCRIPTION:Although approximately 85 million units of red blood cells (RBCs) are transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and othe...

journal_title：Annals of internal medicine

authors： Carson JL,Grossman BJ,Kleinman S,Tinmouth AT,Marques MB,Fung MK,Holcomb JB,Illoh O,Kaplan LJ,Katz LM,Rao SV,Roback JD,Shander A,Tobian AA,Weinstein R,Swinton McLaughlin LG,Djulbegovic B,Clinical Transfusion Medicine Com

更新日期：2012-07-03 00:00:00

abstract：:Differences in blood levels of thyroid hormones have been reported when patients taking synthetic L-thyroxine were shifted from one manufactured form of the hormone to another. Because recent formulation changes have rendered these earlier data obsolete, we did a crossover study to determine differences in bioavailabi...

journal_title：Annals of internal medicine

authors： Hennessey JV,Burman KD,Wartofsky L

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:To determine the incidence, cause, and characteristics of pleural effusions in hospitalized patients with the acquired immunodeficiency syndrome (AIDS). DESIGN:Retrospective. PARTICIPANTS:A total of 222 patients with AIDS hospitalized between January 1986 and January 1992 at the Medical University of South ...

journal_title：Annals of internal medicine

authors： Joseph J,Strange C,Sahn SA

更新日期：1993-06-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the relative importance of adiposity and fat distribution to cardiovascular risk profile. DESIGN:A cross-sectional study. SETTING:Clinical research center funded by the National Institutes of Health. PATIENTS:Convenience sample of 33 healthy premenopausal women with a wide range of body ...

journal_title：Annals of internal medicine

authors： Peiris AN,Sothmann MS,Hoffmann RG,Hennes MI,Wilson CR,Gustafson AB,Kissebah AH

更新日期：1989-06-01 00:00:00

abstract：:Acute bronchitis is an acute cough illness in otherwise healthy adults that usually lasts 1 to 3 weeks. This review describes the pathophysiology of the condition and provides a practical approach to the evaluation and treatment of adults with uncomplicated acute bronchitis. Practical points to be made are:1. Respirat...

journal_title：Annals of internal medicine

authors： Gonzales R,Sande MA

更新日期：2000-12-19 00:00:00

abstract：OBJECTIVE:To critically evaluate the evidence for recommending the screening of asymptomatic men for prostate cancer with a blood test to detect a prostate-specific antigen (PSA). DATA SOURCES:Relevant articles on screening for prostate cancer were identified from MEDLINE searches, from the authors' files, and from th...

journal_title：Annals of internal medicine

authors： Kramer BS,Brown ML,Prorok PC,Potosky AL,Gohagan JK

更新日期：1993-11-01 00:00:00

abstract：:The mechanisms of flushing reactions are pharmacologically and physiologically heterogeneous. Flushing may result from agents acting directly on the vascular smooth muscle or may be mediated by vasomotor nerves. Vasomotor nerves may lead to flushing as a result of events at both peripheral and central sites. In suscep...

journal_title：Annals of internal medicine

authors： Wilkin JK

更新日期：1981-10-01 00:00:00

abstract：:The cause of stroke in young patients frequently cannot be established. Eleven consecutive patients, age 50 and younger, had clinical evidence of cerebral embolization. Results of physical, radiographic, electrocardiographic, and two-dimensional echocardiographic examinations were normal in all patients. During normal...

journal_title：Annals of internal medicine

authors： Harvey JR,Teague SM,Anderson JL,Voyles WF,Thadani U

更新日期：1986-11-01 00:00:00

abstract：:A platelet transfusion from a blood group O donor, immunized 1 month before with Pneumovax, caused a hemolytic reaction in a blood group A recipient. Forty-five of 59 group O donors (76%) and all of nine group B donors immunized with Pneumovax had a fourfold or higher anti-A response. Half of the anti-A antibody in hi...

journal_title：Annals of internal medicine

authors： Siber GR,Ambrosino DM,Gorgone BC

更新日期：1982-05-01 00:00:00

abstract：:Bulimarexia, an eating disorder that is characterized by binge eating followed by self-induced vomiting or abuse of cathartic or diuretic drugs, has been defined as both a sequela of anorexia nervosa and a distinct eating disorder. In this review the presentation, prevalence, and complications of the various eating di...

journal_title：Annals of internal medicine

authors： Harris RT

更新日期：1983-12-01 00:00:00

abstract：:A cohort of both active and retired older cotton textile workers was examined prospectively over a 6-year period to establish the nature and extent of chronic lung disease. Respiratory symptoms and lung function were studied in these workers and in a group of similarly aged controls. The cotton textile workers had hig...

journal_title：Annals of internal medicine

authors： Beck GJ,Schachter EN,Maunder LR,Schilling RS

更新日期：1982-11-01 00:00:00

abstract：:Thirty-nine cases of Legionnaires' disease in a 16-month period were identified in visitors to and residents of Bloomington, Indiana. Thirty-five patients had spent at least one night at the Indiana Memorial Union in the 2 weeks before becoming ill. Five of 32 sporadic cases nationwide between 1 January and 31 March 1...

journal_title：Annals of internal medicine

authors： Politi BD,Fraser DW,Mallison GF,Mohatt JV,Morris GK,Patton CM,Feeley JC,Telle RD,Bennett JV

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:The fecal immunochemical test (FIT) is a common method for colorectal cancer (CRC) screening, yet its acceptability and performance over several rounds of annual testing are largely unknown. OBJECTIVE:To assess FIT performance characteristics over 4 rounds of annual screening. DESIGN:Retrospective cohort s...

journal_title：Annals of internal medicine

authors： Jensen CD,Corley DA,Quinn VP,Doubeni CA,Zauber AG,Lee JK,Zhao WK,Marks AR,Schottinger JE,Ghai NR,Lee AT,Contreras R,Klabunde CN,Quesenberry CP,Levin TR,Mysliwiec PA

更新日期：2016-04-05 00:00:00

abstract：:Transmission of the human immunodeficiency virus (HIV) was studied in a group of patients with cancer who received transfusion of blood components harvested from a single, asymptomatic, seropositive donor. Of ten living recipients, nine had antibodies to the virus in fresh or cryopreserved sera at a median of 384 days...

journal_title：Annals of internal medicine

authors： Anderson KC,Gorgone BC,Marlink RG,Ferriani R,Essex ME,Benz PM,Groopman JE

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:An effective national biosurveillance system expedites outbreak recognition and facilitates response coordination at the federal, state, and local levels. The BioSense system, used at the Centers for Disease Control and Prevention, incorporates chief complaints but not data from the whole encounter note into...

journal_title：Annals of internal medicine

authors： Elkin PL,Froehling DA,Wahner-Roedler DL,Brown SH,Bailey KR

更新日期：2012-01-03 00:00:00

abstract：BACKGROUND:Extended-duration low-molecular-weight heparin has been shown to prevent venous thromboembolism (VTE) in high-risk surgical patients. OBJECTIVE:To evaluate the efficacy and safety of extended-duration enoxaparin thromboprophylaxis in acutely ill medical patients. DESIGN:Randomized, parallel, placebo-contro...

journal_title：Annals of internal medicine

authors： Hull RD,Schellong SM,Tapson VF,Monreal M,Samama MM,Nicol P,Vicaut E,Turpie AG,Yusen RD,EXCLAIM (Extended Prophylaxis for Venous ThromboEmbolism in Acutely Ill Medical Patients With Prolonged Immobilization) study.

更新日期：2010-07-06 00:00:00

abstract：BACKGROUND:Recent evidence shows that arthroscopic partial meniscectomy (APM) offers no benefit over conservative treatment of patients with a degenerative meniscus tear. However, patients who report mechanical symptoms (sensations of knee catching or locking) may benefit from APM. OBJECTIVE:To assess whether APM impr...

journal_title：Annals of internal medicine

authors： Sihvonen R,Englund M,Turkiewicz A,Järvinen TL,Finnish Degenerative Meniscal Lesion Study Group.

更新日期：2016-04-05 00:00:00

abstract：:Medical devices have become an integral part of hospital-based care but also predispose patients to more than 850 000 device-related infections annually. Devices predispose to infection by damaging or invading epithelial and mucosal barriers to infection, by supporting growth of microorganisms and thus serving as rese...

journal_title：Annals of internal medicine

authors： Stamm WE

更新日期：1978-11-01 00:00:00

abstract：:This paper is part 1 of a 2-part series on interpretation of 12-lead resting electrocardiograms (ECGs). Part 1 is a position paper that presents recommendations for initial competency, competency assessment, and maintenance of competency on ECG interpretation, as well as recommendations for the role of computer-assist...

journal_title：Annals of internal medicine

authors： Salerno SM,Alguire PC,Waxman HS,American College of Physicians.

更新日期：2003-05-06 00:00:00

abstract：:To understand the factors that distinguish terminally ill, incompetent patients who are given do-not-resuscitate status by physicians against the wishes of the patient's family, I reviewed the charts of 20 such patients (cases) seen in consultation by the ethics committee at the Massachusetts General Hospital over 10 ...

journal_title：Annals of internal medicine

authors： Brennan TA

更新日期：1988-11-15 00:00:00

abstract：:Dietary deficiency of vitamin B-12 has been reported, yet most people ingesting vitamin-B12-deficient diets even for many years appear to achieve a balance that does not lead to overt signs and symptoms of deficiency. I present the case of a vegan of 25 years' duration who developed severe neurologic abnormalities due...

journal_title：Annals of internal medicine

authors： Carmel R

更新日期：1978-05-01 00:00:00

abstract：:The pursuit of the ideal tumor marker has generated many tests for use in the diagnosis and management of cancer, several of which are now widely available. Tumor markers have five potential uses in patient care: They can be used for screening, for diagnosis, for establishing prognosis, for monitoring treatment, and f...

journal_title：Annals of internal medicine

authors： Bates SE

更新日期：1991-10-15 00:00:00

abstract：STUDY OBJECTIVE:To determine the effect of a nurse-managed intervention for smoking cessation in patients who have had a myocardial infarction. DESIGN:Randomized, with a 6-month treatment period and a 6-month follow-up. SETTING:Kaiser Foundation hospitals in Redwood City, Santa Clara, Hayward, and San Jose, Californi...

journal_title：Annals of internal medicine

authors： Taylor CB,Houston-Miller N,Killen JD,DeBusk RF

更新日期：1990-07-15 00:00:00

abstract：:Increasingly, interventions aimed at improving care are likely to use such technologies as machine learning and artificial intelligence. However, health care has been relatively late to adopt them. This article provides clinical examples in which machine learning and artificial intelligence are already in use in healt...

journal_title：Annals of internal medicine

authors： Bates DW,Auerbach A,Schulam P,Wright A,Saria S

更新日期：2020-06-02 00:00:00

abstract：OBJECTIVE:To determine whether prolonging the duration of tamoxifen administration beyond the cessation of a combined chemotherapy regimen benefits patients with primary breast cancer with positive findings in axillary nodes who benefit initially from the combined regimen. DESIGN:Nonrandomized, nonconcurrent cohort st...

journal_title：Annals of internal medicine

authors： Fisher B,Brown A,Wolmark N,Redmond C,Wickerham DL,Wittliff J,Dimitrov N,Legault-Poisson S,Schipper H,Prager D

更新日期：1987-05-01 00:00:00