Balloon valvuloplasty in adult aortic stenosis: determinants of clinical outcome.

abstract：:Questionnaire II of the National Study of Internal Medicine Manpower was directed to all of the 1502 subspecialty training programs in the United States and Puerto Rico. The overall response rate was 86%. For the years 1972-1973 through 1976-1977 the number of fellows in subspecialty training grew at an average rate o...

journal_title：Annals of internal medicine

authors： Tarlov AR,Weil PA,Schleiter MK

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:The Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 global treatment target aims to achieve 73% virologic suppression among HIV-infected persons worldwide by 2020. OBJECTIVE:To estimate the clinical and economic value of reaching this ambitious goal in South Africa, by using a microsimulation m...

journal_title：Annals of internal medicine

authors： Walensky RP,Borre ED,Bekker LG,Resch SC,Hyle EP,Wood R,Weinstein MC,Ciaranello AL,Freedberg KA,Paltiel AD

更新日期：2016-09-06 00:00:00

abstract：OBJECTIVE:To define the incidence of and possible risk factors for invasive Haemophilus influenzae disease in adults. DESIGN:Prospective, population-based surveillance of hospital and referral bacteriology laboratories. SETTING:Metropolitan Atlanta, Georgia community. PATIENTS:All patients with H. influenzae isolate...

journal_title：Annals of internal medicine

authors： Farley MM,Stephens DS,Brachman PS Jr,Harvey RC,Smith JD,Wenger JD

更新日期：1992-05-15 00:00:00

abstract：:Plasma lipid and lipoprotein-cholesterol levels were measured in 10 insulin-dependent (Type I) diabetics taking their usual dose of conventionally administered insulin during 6 months of a continuous subcutaneous insulin infusion delivered with a small, portable, battery-powered pump. With this insulin delivery system...

journal_title：Annals of internal medicine

authors： Dunn FL,Pietri A,Raskin P

更新日期：1981-10-01 00:00:00

abstract：:Arterial blood gas analysis is used to evaluate oxygen and carbon dioxide gas exchange and acid-base status. Few studies identify indications for arterial blood gas analysis, especially with regard to optimizing the quality of patient care. General indications in severely ill adults usually include pathophysiologic ab...

journal_title：Annals of internal medicine

authors： Raffin TA

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:Variants in genes involved in warfarin metabolism and sensitivity affect individual warfarin requirements and the risk for bleeding. Testing for these variant alleles might allow more personalized dosing of warfarin during the induction phase. In 2007, the U.S. Food and Drug Administration changed the labeli...

journal_title：Annals of internal medicine

authors： Eckman MH,Rosand J,Greenberg SM,Gage BF

更新日期：2009-01-20 00:00:00

abstract：OBJECTIVE:To determine whether a cytogenetic response after interferon-alpha therapy in patients with chronic myelogenous leukemia is independently associated with improved survival. DESIGN:Retrospective analysis. PATIENTS:274 patients with a diagnosis of Philadelphia chromosome-positive chronic myelogenous leukemia ...

journal_title：Annals of internal medicine

authors： Kantarjian HM,Smith TL,O'Brien S,Beran M,Pierce S,Talpaz M

更新日期：1995-02-15 00:00:00

abstract：:Recent research on human macrophage activation has reemphasized the critical role of the lymphokine-secreting T cell in converting quiescent macrophages to efficient microbicidal phagocytes. Interferon-gamma, a key lymphokine secreted by antigen-triggered T4+ helper cells, is capable of inducing the macrophage to act ...

journal_title：Annals of internal medicine

authors： Murray HW

更新日期：1988-04-01 00:00:00

abstract：:The U.S. Food and Drug Administration (FDA) Amendments Act of 2007 mandated that the FDA develop a system for using automated health care data to identify risks of marketed drugs and other medical products. The Observational Medical Outcomes Partnership is a public-private partnership among the FDA, academia, data own...

journal_title：Annals of internal medicine

authors： Stang PE,Ryan PB,Racoosin JA,Overhage JM,Hartzema AG,Reich C,Welebob E,Scarnecchia T,Woodcock J

更新日期：2010-11-02 00:00:00

abstract：OBJECTIVE:To determine in female tennis and squash players the effect of biological age (that is, the starting age of playing relative to the age at menarche) at which tennis or squash playing was started on the difference in bone mineral content between the playing and non-playing arms. DESIGN:Cross-sectional study. ...

journal_title：Annals of internal medicine

authors： Kannus P,Haapasalo H,Sankelo M,Sievänen H,Pasanen M,Heinonen A,Oja P,Vuori I

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Screening women for Chlamydia trachomatis in family planning clinics is associated with a reduced incidence of chlamydial sequelae. However, the question of whom to screen to maintain efficient use of resources remains controversial. OBJECTIVE:To assess the cost-effectiveness of chlamydial screening done ac...

journal_title：Annals of internal medicine

authors： Howell MR,Quinn TC,Gaydos CA

更新日期：1998-02-15 00:00:00

abstract：BACKGROUND:Memphis and Shelby County, Tennessee, experienced an epidemic of hepatitis A in 1994 and 1995. More than 1700 cases were reported. OBJECTIVE:To characterize the clinical features of patients hospitalized during a large urban epidemic of hepatitis A. DESIGN:Retrospective chart review. SETTING:15 acute care...

journal_title：Annals of internal medicine

authors： Willner IR,Uhl MD,Howard SC,Williams EQ,Riely CA,Waters B

更新日期：1998-01-15 00:00:00

abstract：:Ambulatory education has become an essential part of all internal medicine residencies. To develop excellent ambulatory education programs, we must thoroughly understand the opportunities available in such a setting, and the leaders in internal medicine must be willing to experiment with nontraditional locations and r...

journal_title：Annals of internal medicine

authors： Schuster BL

更新日期：1992-06-15 00:00:00

abstract：:In the 5 years since its release for clinical use, acyclovir (9-[2-hydroxyethoxymethyl]guanine) has proved to be a safe and effective agent for therapy of herpes simplex and varicella-zoster infections. The drug's availability in topical, oral, and intravenous preparations has allowed its use in a range of clinical si...

journal_title：Annals of internal medicine

authors： Dorsky DI,Crumpacker CS

更新日期：1987-12-01 00:00:00

abstract：:For over 200 years digitalis compounds have been used to treat atrial fibrillation. The rapid ventricular response to atrial fibrillation is frequently treated with digoxin to produce a controlled heart rate. Digoxin has also been proposed as a treatment for terminating recent-onset atrial fibrillation, for maintainin...

journal_title：Annals of internal medicine

authors： Falk RH,Leavitt JI

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:The appropriate roles for several diagnostic tests for coronary disease are uncertain. OBJECTIVE:To evaluate the cost-effectiveness of alternative approaches to diagnosis of coronary disease. DESIGN:Meta-analysis of the accuracy of alternative diagnostic tests plus decision analysis to assess the health ou...

journal_title：Annals of internal medicine

authors： Garber AM,Solomon NA

更新日期：1999-05-04 00:00:00

abstract：:The sharp rise in drug abuse in the past decade has led to the development of new sources of information on drug-abuse trends. These include surveys, drug-related emergencies, drug-abuse treatment, hepatitis rates, and various types of law enforcement information. This paper summarizes data currently available for her...

journal_title：Annals of internal medicine

authors： Greene MH,Nightingale SL,DuPont RL

更新日期：1975-09-01 00:00:00

abstract：:Ten patients with lupus nephritis and marked proteinuria (3.9 g or more/d) that did not respond adequately to treatment with prednisone alone or prednisone in combination with azathioprine were treated with total lymphoid irradiation in an uncontrolled feasibility study. Within 6 weeks after the start of total lymphoi...

journal_title：Annals of internal medicine

authors： Strober S,Field E,Hoppe RT,Kotzin BL,Shemesh O,Engleman E,Ross JC,Myers BD

更新日期：1985-04-01 00:00:00

abstract：:Some important health policy topics, such as those related to the delivery, organization, and financing of health care, present substantial challenges to established methods for evidence synthesis. For example, such reviews may ask: What is the effect of for-profit versus not-for-profit delivery of care on patient out...

journal_title：Annals of internal medicine

authors： Bravata DM,McDonald KM,Shojania KG,Sundaram V,Owens DK

更新日期：2005-06-21 00:00:00

abstract：STUDY OBJECTIVE:To evaluate the tolerance and safety of oral dextran sulfate (UA001), a potent in-vitro inhibitor of human immunodeficiency virus (HIV) in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. DESIGN:Unblinded, dose-escalation 8-week trial. SETTING:An AIDS outpatient cl...

journal_title：Annals of internal medicine

authors： Abrams DI,Kuno S,Wong R,Jeffords K,Nash M,Molaghan JB,Gorter R,Ueno R

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Despite convincing evidence that lowering blood pressure decreases cardiovascular morbidity and mortality, the hypertension burden remains high and control rates are poor in developing countries. OBJECTIVE:To assess the effectiveness of 2 community-based interventions on blood pressure in hypertensive adult...

journal_title：Annals of internal medicine

authors： Jafar TH,Hatcher J,Poulter N,Islam M,Hashmi S,Qadri Z,Bux R,Khan A,Jafary FH,Hameed A,Khan A,Badruddin SH,Chaturvedi N,Hypertension Research Group.

更新日期：2009-11-03 00:00:00

abstract：BACKGROUND:Extracts of the medicinal plant Tripterygium wilfordii Hook F (TwHF) have been used in China for centuries to treat a spectrum of inflammatory diseases. OBJECTIVE:To compare the benefits and side effects of TwHF extract with those of sulfasalazine for the treatment of active rheumatoid arthritis. DESIGN:Ra...

journal_title：Annals of internal medicine

authors： Goldbach-Mansky R,Wilson M,Fleischmann R,Olsen N,Silverfield J,Kempf P,Kivitz A,Sherrer Y,Pucino F,Csako G,Costello R,Pham TH,Snyder C,van der Heijde D,Tao X,Wesley R,Lipsky PE

更新日期：2009-08-18 00:00:00

abstract：BACKGROUND:The long-term risk for fatal pulmonary embolism (PE) after treatment of venous thromboembolism (VTE) may be an important factor in the decision to discontinue this treatment. OBJECTIVE:To provide reliable and precise estimates of the annual risk for fatal PE and the case-fatality rate of disease recurrence ...

journal_title：Annals of internal medicine

authors： Douketis JD,Gu CS,Schulman S,Ghirarduzzi A,Pengo V,Prandoni P

更新日期：2007-12-04 00:00:00

abstract：OBJECTIVE:To determine the relations among esophageal dysfunction, gastroesophageal reflux, and lung involvement in patients with systemic sclerosis. DESIGN:Retrospective review of esophageal motility, esophageal pH, and pulmonary function data. SETTING:University hospital outpatient clinic and community. PATIENTS:3...

journal_title：Annals of internal medicine

authors： Troshinsky MB,Kane GC,Varga J,Cater JR,Fish JE,Jimenez SA,Castell DO

更新日期：1994-07-01 00:00:00

abstract：STUDY OBJECTIVE:To determine whether obesity preceded knee osteoarthritis and was thus a possible cause. DESIGN:Cohort study with weight and other important variables measured in 1948 to 1951 (mean age of subjects, 37 years) and knee arthritis evaluated in 1983 to 1985 (mean age of subjects, 73 years). SETTING:Popula...

journal_title：Annals of internal medicine

authors： Felson DT,Anderson JJ,Naimark A,Walker AM,Meenan RF

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Recent postmarketing trials produced conflicting results about the risk for hospitalized heart failure (hHF) associated with dipeptidyl peptidase-4 (DPP-4) inhibitors, creating uncertainty about the safety of these antihyperglycemic agents. OBJECTIVE:To examine the associations of hHF with saxagliptin and s...

journal_title：Annals of internal medicine

authors： Toh S,Hampp C,Reichman ME,Graham DJ,Balakrishnan S,Pucino F,Hamilton J,Lendle S,Iyer A,Rucker M,Pimentel M,Nathwani N,Griffin MR,Brown NJ,Fireman BH

更新日期：2016-06-07 00:00:00

abstract：:The safety of using inhaled beclomethasone dipropionate for the treatment of severe asthma during pregnancy was evaluated during 45 pregnancies in 40 women. Despite chronic administration of theophylline and, in some women, ephedrine, the asthma was so severe that corticosteroids were essential to prevent emergency ro...

journal_title：Annals of internal medicine

authors： Greenberger PA,Patterson R

更新日期：1983-04-01 00:00:00

abstract：:The relation of menopause to cardiovascular disease incidence was examined in women less than 55 years old from the cohort of 2873 women in the initial Framingham examination. Although the number of person-years of experience during the 20 years of observation was nearly the same for premenopausal and postmenopausal s...

journal_title：Annals of internal medicine

authors： Kannel WB,Hjortland MC,McNamara PM,Gordon T

更新日期：1976-10-01 00:00:00

abstract：:Enlargement of the pituitary gland associated with primary hypothyroidism was observed in two patients. Serum thyroid-stimulating hormone (TSH) concentration and the TSH response to thyrotropin-releasing hormone were increased in both. Other pituitary function tests were subnormal in both patients, suggesting that a t...

journal_title：Annals of internal medicine

authors： Vagenakis AG,Dole K,Braverman LE

更新日期：1976-08-01 00:00:00

abstract：:The clinical implications of newly acquired left bundle-branch block (LBBB) were examined prospectively in the Framingham Study population. During 18 years of observation 55 people developed LBBB. The mean age at the onset of LBBB was 62; LBBB occurred largely in people with antecedent hypertension, cardiac enlargemen...

journal_title：Annals of internal medicine

authors： Schneider JF,Thomas HE Jr,Kreger BE,McNamara PM,Kannel WB

更新日期：1979-03-01 00:00:00