Internists' attitudes about clinical practice guidelines.

abstract：:Recently developed radioligand binding techniques permit direct investigation of the alpha- and beta-adrenergic receptors for catecholamines in a wide variety of tissues. These techniques allow the receptors to be quantitated, characterized, and studied under varying conditions of physiologic and pathophysiologic inte...

journal_title：Annals of internal medicine

authors： Lefkowitz RJ

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Short-term aspirin therapy can lower the risk for venous thromboembolism (VTE) in high-risk patients, but whether the long-term use of low-dose aspirin reduces risk in healthy adults is uncertain. OBJECTIVE:To test the efficacy of long-term aspirin therapy for preventing VTE. DESIGN:Secondary analysis of a...

journal_title：Annals of internal medicine

authors： Glynn RJ,Ridker PM,Goldhaber SZ,Buring JE

更新日期：2007-10-16 00:00:00

abstract：:The term functional somatic syndrome has been applied to several related syndromes characterized more by symptoms, suffering, and disability than by consistently demonstrable tissue abnormality. These syndromes include multiple chemical sensitivity, the sick building syndrome, repetition stress injury, the side effect...

journal_title：Annals of internal medicine

authors： Barsky AJ,Borus JF

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Homeless persons have high mortality rates. OBJECTIVE:To ascertain causes of death in a group of homeless persons. DESIGN:Cohort study. PATIENTS:17,292 adults seen by the Boston Health Care for the Homeless Program from 1988 to 1993. MEASUREMENTS:Cause-specific mortality rates adjusted for race and rate ...

journal_title：Annals of internal medicine

authors： Hwang SW,Orav EJ,O'Connell JJ,Lebow JM,Brennan TA

更新日期：1997-04-15 00:00:00

abstract：STUDY OBJECTIVE:To determine the safety of withholding anticoagulant therapy in pregnant patients with clinically suspected deep-vein thrombosis who have negative results by serial impedance plethysmography. DESIGN:Prospective study evaluating prognosis by long-term follow-up to 3 months postpartum in all patients. S...

journal_title：Annals of internal medicine

authors： Hull RD,Raskob GE,Carter CJ

更新日期：1990-05-01 00:00:00

abstract：SOURCE CITATION:Baldetti L, Melillo F, Moroni F, et al. Meta-analysis comparing P2Y12 inhibitors in acute coronary syndrome. Am J Cardiol. 2020;125;1815-22. 32305225. ...

journal_title：Annals of internal medicine

authors： Elgendy IY

更新日期：2020-09-15 00:00:00

abstract：Background:FLU-v is a broad-spectrum influenza vaccine that induces antibodies and cell-mediated immunity. Objective:To compare the safety, immunogenicity, and exploratory efficacy of different formulations and dosing regimens of FLU-v versus placebo. Design:Randomized, double-blind, placebo-controlled, single-center...

journal_title：Annals of internal medicine

authors： Pleguezuelos O,Dille J,de Groen S,Oftung F,Niesters HGM,Islam MA,Næss LM,Hungnes O,Aldarij N,Idema DL,Perez AF,James E,Frijlink HW,Stoloff G,Groeneveld P,Hak E

更新日期：2020-04-07 00:00:00

abstract：:Arterial blood gas analysis is used to evaluate oxygen and carbon dioxide gas exchange and acid-base status. Few studies identify indications for arterial blood gas analysis, especially with regard to optimizing the quality of patient care. General indications in severely ill adults usually include pathophysiologic ab...

journal_title：Annals of internal medicine

authors： Raffin TA

更新日期：1986-09-01 00:00:00

abstract：:To assess the course and prognosis of salicylate-induced pulmonary edema, we reviewed the records of 36 consecutive patients admitted with serum salicylate levels greater than 30 mg/dL. Pulmonary edema developed in eight patients, and pulmonary infiltrates were never seen in 28 patients. Several features distinguished...

journal_title：Annals of internal medicine

authors： Heffner JE,Sahn SA

更新日期：1981-10-01 00:00:00

abstract：:Acute bronchitis is an acute cough illness in otherwise healthy adults that usually lasts 1 to 3 weeks. This review describes the pathophysiology of the condition and provides a practical approach to the evaluation and treatment of adults with uncomplicated acute bronchitis. Practical points to be made are:1. Respirat...

journal_title：Annals of internal medicine

authors： Gonzales R,Sande MA

更新日期：2000-12-19 00:00:00

abstract：BACKGROUND:The magnitude, consistency, and manner of association between sedentary time and outcomes independent of physical activity remain unclear. PURPOSE:To quantify the association between sedentary time and hospitalizations, all-cause mortality, cardiovascular disease, diabetes, and cancer in adults independent ...

journal_title：Annals of internal medicine

authors： Biswas A,Oh PI,Faulkner GE,Bajaj RR,Silver MA,Mitchell MS,Alter DA

更新日期：2015-01-20 00:00:00

abstract：BACKGROUND:Markers are needed for assessing response to antiretroviral therapy over time. The CD4+ lymphocyte count is one such surrogate, but it is relatively weak. OBJECTIVE:To assess the association of changes in plasma human immunodeficiency virus (HIV) RNA level and CD4+ lymphocyte count with progression to the a...

journal_title：Annals of internal medicine

authors： O'Brien WA,Hartigan PM,Daar ES,Simberkoff MS,Hamilton JD

更新日期：1997-06-15 00:00:00

abstract：STUDY OBJECTIVE:To define the clinical and hematologic effects of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) on patients with chronic severe neutropenia. DESIGN:Open-label, phase II study of rhGM-CSF. SETTING:Inpatient hematology and surgery clinic at a university medical center. P...

journal_title：Annals of internal medicine

authors： Ganser A,Ottmann OG,Erdmann H,Schulz G,Hoelzer D

更新日期：1989-12-01 00:00:00

abstract：OBJECTIVE:To determine whether depressed mood or life events are associated with an exacerbation of inflammatory bowel disease. DESIGN:A prospective study of a consecutive sample of patients with relapsing inflammatory bowel disease, followed by monthly questionnaires and periodic office visits. SETTING:A referral-ba...

journal_title：Annals of internal medicine

authors： North CS,Alpers DH,Helzer JE,Spitznagel EL,Clouse RE

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:U.S. HIV treatment guidelines recommend branded once-daily, 1-pill efavirenz-emtricitabine-tenofovir as first-line antiretroviral therapy (ART). With the anticipated approval of generic efavirenz in the United States, a once-daily, 3-pill alternative (generic efavirenz, generic lamivudine, and tenofovir) wil...

journal_title：Annals of internal medicine

authors： Walensky RP,Sax PE,Nakamura YM,Weinstein MC,Pei PP,Freedberg KA,Paltiel AD,Schackman BR

更新日期：2013-01-15 00:00:00

abstract：BACKGROUND:Early prenatal care is vital for improving maternal health outcomes and health behaviors, but medically vulnerable and underserved populations are less likely to begin prenatal care in the first trimester. In 2017, the Health Center Program provided safety-net care to more than 27 million persons, including ...

journal_title：Annals of internal medicine

authors： Robbins C,Martocci S

更新日期：2020-12-01 00:00:00

abstract：:We treated 289 men with nongonococcal urethritis in a randomized, double-blind study with minocycline, 100 mg once or twice daily for 7 or 21 days. Ureaplasma urealyticum was isolated before treatment from 167 (58%). The pretherapy isolates from 82 men re-examined 6 to 8 days after initiation of treatment were viable....

journal_title：Annals of internal medicine

authors： Stimson JB,Hale J,Bowie WR,Holmes KK

更新日期：1981-02-01 00:00:00

abstract：:One hundred ninety-eight patients with chronic myelogenous leukemia received marrow transplants after intensive chemotherapy and total body irradiation. Multivariate analysis showed disease status at time of transplantation to be the most powerful predictor of survival. The probability of long-term survival for alloge...

journal_title：Annals of internal medicine

authors： Thomas ED,Clift RA,Fefer A,Appelbaum FR,Beatty P,Bensinger WI,Buckner CD,Cheever MA,Deeg HJ,Doney K

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Hematopoietic stem cell transplantation (HSCT) is increasingly used to treat multiple malignant and nonmalignant conditions. The risk for cardiovascular disease after the procedure has not been well-described. OBJECTIVE:To compare rates and hazards of cardiovascular-related hospitalization and death among p...

journal_title：Annals of internal medicine

authors： Chow EJ,Mueller BA,Baker KS,Cushing-Haugen KL,Flowers ME,Martin PJ,Friedman DL,Lee SJ

更新日期：2011-07-05 00:00:00

abstract：STUDY OBJECTIVE:To determine if the combination of ganciclovir and intravenous cytomegalovirus immunoglobulin is effective in patients with cytomegalovirus pneumonia after bone marrow transplant. DESIGN:Consecutive entry trial with treatment for a minimum of 14 days. PATIENTS:Consecutive sample of 25 patients with bo...

journal_title：Annals of internal medicine

authors： Reed EC,Bowden RA,Dandliker PS,Lilleby KE,Meyers JD

更新日期：1988-11-15 00:00:00

abstract：:Acute coronary syndromes--unstable angina, myocardial infarction, and sudden cardiac death--are caused by acute disruption of an unstable coronary atheroma. Unstable plaques have three histologic characteristics: a large lipid core, many inflammatory cells, and a thin fibrous cap. Because the unstable plaque is not ne...

journal_title：Annals of internal medicine

authors： Forrester JS

更新日期：2002-11-19 00:00:00

abstract：Background:Biosimilars are of growing clinical, regulatory, and commercial importance. Purpose:To summarize evidence about the bioequivalence between biosimilar and reference tumor necrosis factor-α (TNF-α) inhibitors. Data Sources:PubMed, EMBASE, Cochrane Central Register of Controlled Trials, and LILACS from incept...

journal_title：Annals of internal medicine

authors： Chingcuanco F,Segal JB,Kim SC,Alexander GC

更新日期：2016-10-18 00:00:00

abstract：:Patients with serious psychiatric disorders are frequently treated by primary care physicians, who may have difficulty keeping up with recent advances in psychiatry. This paper presents an updated synopsis for three major psychiatric illnesses: major depression, bipolar disorder, and schizophrenia. Current definitions...

journal_title：Annals of internal medicine

authors： Glick ID,Suppes T,DeBattista C,Hu RJ,Marder S

更新日期：2001-01-02 00:00:00

abstract：:To characterize the role of cardiac function in septic shock, serial radionuclide cineangiographic and hemodynamic evaluations were done on 20 patients with documented septic shock. Although all patients had a normal or elevated cardiac index, 10 patients had moderate to severe depression of their ejection fraction wi...

journal_title：Annals of internal medicine

authors： Parker MM,Shelhamer JH,Bacharach SL,Green MV,Natanson C,Frederick TM,Damske BA,Parrillo JE

更新日期：1984-04-01 00:00:00

abstract：:In two patients with thyroiditis caused by Coccidioides immitis, presented thyroid symptoms and findings were characteristic of subacute thyroiditis. Fine needle aspiration biopsy of the thyroid proved useful in establishing the diagnosis of coccidioidomycosis. This is the first report of coccidioidomycosis presenting...

journal_title：Annals of internal medicine

authors： Loeb JM,Livermore BM,Wofsy D

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Chronic myelogenous leukemia (CML) is an indolent but ultimately fatal disease. Because the natural history of CML varies and quality of life with CML may be excellent until shortly before death, deciding whether and when to pursue unrelated donor bone marrow transplantation is often difficult. OBJECTIVE:To...

journal_title：Annals of internal medicine

authors： Lee SJ,Kuntz KM,Horowitz MM,McGlave PB,Goldman JM,Sobocinski KA,Hegland J,Kollman C,Parsons SK,Weinstein MC,Weeks JC,Antin JH

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:The renin-angiotensin system is involved in adipocyte growth and differentiation and possibly in adipose tissue metabolism. OBJECTIVE:To investigate the association of polymorphism in the angiotensin-converting enzyme (ACE) I/D gene, angiotensinogen M235T gene, and angiotensin II type 1 receptor A1166C gene...

journal_title：Annals of internal medicine

authors： Strazzullo P,Iacone R,Iacoviello L,Russo O,Barba G,Russo P,D'Orazio A,Barbato A,Cappuccio FP,Farinaro E,Siani A,Olivetti Prospective Heart Study.

更新日期：2003-01-07 00:00:00

abstract：PURPOSE:To compare the diagnostic accuracy of computed tomography (CT) and positron emission tomography (PET) with 18-fluorodeoxyglucose (FDG) for mediastinal staging in patients with non-small-cell lung cancer and to determine whether test results are conditionally dependent (the sensitivity and specificity of FDG-PET...

journal_title：Annals of internal medicine

authors： Gould MK,Kuschner WG,Rydzak CE,Maclean CC,Demas AN,Shigemitsu H,Chan JK,Owens DK

更新日期：2003-12-02 00:00:00

abstract：BACKGROUND:The risk for and determinants of transmission of tuberculosis in hospitals caring for moderate numbers of patients with tuberculosis remain uncertain. OBJECTIVE:To study the association of tuberculin conversion among health care workers with ventilation of patient care areas. DESIGN:Cross-sectional observa...

journal_title：Annals of internal medicine

authors： Menzies D,Fanning A,Yuan L,FitzGerald JM

更新日期：2000-11-21 00:00:00

abstract：:Early defibrillation is the most important determinant of survival for victims of cardiac arrest due to ventricular fibrillation. The automated external defibrillator (AED) was developed as the result of the American Heart Association's Public Access Defibrillation initiative. The goal of this initiative is to place A...

journal_title：Annals of internal medicine

authors： Takata TS,Page RL,Joglar JA

更新日期：2001-12-04 00:00:00