The Canadian Cardiovascular Society grading scale for angina pectoris: is it time for refinements?

abstract：:Pemphigus is an autoimmune intraepidermal bullous disease involving the skin and mucous membranes. There are four clinically recognized variants of this disease. The histopathologic hallmark is acantholysis, which is disruption of normal cell-to-cell adhesion. Patients produce an IgG antibody directed against an antig...

journal_title：Annals of internal medicine

authors：

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Screening for hereditary hemochromatosis is traditionally done by using serum iron studies. However, mutation analysis of the hemochromatosis-associated HFE gene has recently become available. OBJECTIVE:To compare the cost-effectiveness of no screening with four screening strategies that incorporate HFE gen...

journal_title：Annals of internal medicine

authors： El-Serag HB,Inadomi JM,Kowdley KV

更新日期：2000-02-15 00:00:00

abstract：BACKGROUND:Medical students may be at high risk for occupational exposures to blood. OBJECTIVE:To measure the frequency of medical students' exposure to infectious body substances, to identify factors that affect the probability of such exposure, and to suggest targets for the prevention of such exposure. DESIGN:Revi...

journal_title：Annals of internal medicine

authors： Osborn EH,Papadakis MA,Gerberding JL

更新日期：1999-01-05 00:00:00

abstract：BACKGROUND:The renin-angiotensin system is involved in adipocyte growth and differentiation and possibly in adipose tissue metabolism. OBJECTIVE:To investigate the association of polymorphism in the angiotensin-converting enzyme (ACE) I/D gene, angiotensinogen M235T gene, and angiotensin II type 1 receptor A1166C gene...

journal_title：Annals of internal medicine

authors： Strazzullo P,Iacone R,Iacoviello L,Russo O,Barba G,Russo P,D'Orazio A,Barbato A,Cappuccio FP,Farinaro E,Siani A,Olivetti Prospective Heart Study.

更新日期：2003-01-07 00:00:00

abstract：:Opioid dependence is a chronic relapsing medical condition with substantial health and societal complications. Recent federal initiatives are designed to enhance the medical treatment of patients with opioid dependence and will expand the role of internists in the care of these patients. These initiatives include a pr...

journal_title：Annals of internal medicine

authors： Fiellin DA,O'Connor PG

更新日期：2002-10-15 00:00:00

abstract：:Methylation of DNA is a biochemical modification that can influence gene expression and is involved in inactivating one of the two X chromosomes in women. Evidence that has accumulated in the past 10 years suggests that cancer cells usurp this physiologic mechanism and use it to their benefit by inactivating tumor sup...

journal_title：Annals of internal medicine

authors： Santini V,Kantarjian HM,Issa JP

更新日期：2001-04-03 00:00:00

abstract：STUDY OBJECTIVE:To determine the sensitivity of herpes simplex virus isolates to acyclovir and the importance of resistant isolates in hospitalized patients. DESIGN:Retrospective incidence cohort study. SETTING:All herpes simplex virus isolates cultured over 1 year from patients followed at a tertiary care center. P...

journal_title：Annals of internal medicine

authors： Englund JA,Zimmerman ME,Swierkosz EM,Goodman JL,Scholl DR,Balfour HH Jr

更新日期：1990-03-15 00:00:00

abstract：:During the early 1990s, the U.S. government addressed the issue of providing universal health care to all its citizens. Although this issue has not been completely resolved, centralization of electronic data and sharing of health care information among insurers and providers have been pursued. The emergence of electro...

journal_title：Annals of internal medicine

authors： Gostin L

更新日期：1997-10-15 00:00:00

abstract：OBJECTIVE:To describe how the results of bone densitometry affect women's decisions about measures to prevent fractures and to determine whether labeling women as having below-normal bone density has adverse effects. DESIGN:Mail survey of a random sample of women. SETTING:Four community hospitals in the San Francisco...

journal_title：Annals of internal medicine

authors： Rubin SM,Cummings SR

更新日期：1992-06-15 00:00:00

abstract：:Medical school graduates are avoiding primary care. The very aspects that once attracted students have been subverted. The breadth of practice that was once appealing has become the breadth of heavy-handed scrutiny, as politicians and business leaders have demanded quality--simplistically defined as dogmatic adherence...

journal_title：Annals of internal medicine

authors： Norenberg DD

更新日期：2009-05-19 00:00:00

abstract：:We prospectively studied the evaluation of dementia in 107 unselected outpatients; 83 had so-called "irreversible" dementias, including 74 who had an Alzheimer-type dementia. Fifteen patients had potentially reversible dementias, of which hypothyroidism and drug toxicity were the commonest causes. Distinguishing featu...

journal_title：Annals of internal medicine

authors： Larson EB,Reifler BV,Featherstone HJ,English DR

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Recent evidence shows that arthroscopic partial meniscectomy (APM) offers no benefit over conservative treatment of patients with a degenerative meniscus tear. However, patients who report mechanical symptoms (sensations of knee catching or locking) may benefit from APM. OBJECTIVE:To assess whether APM impr...

journal_title：Annals of internal medicine

authors： Sihvonen R,Englund M,Turkiewicz A,Järvinen TL,Finnish Degenerative Meniscal Lesion Study Group.

更新日期：2016-04-05 00:00:00

abstract：OBJECTIVE:To identify the cause of a hypersensitivity pneumonitis and to determine its pathogenesis. DESIGN:Case study. SETTING:Intensive care unit of a referral hospital. PATIENT:A 51-year-old man with chronic bronchitis who developed a hypersensitivity pneumonitis within 1 month after exposure to minocycline, amox...

journal_title：Annals of internal medicine

authors： Guillon JM,Joly P,Autran B,Denis M,Akoun G,Debré P,Mayaud C

更新日期：1992-09-15 00:00:00

abstract：OBJECTIVE:To determine the relations among esophageal dysfunction, gastroesophageal reflux, and lung involvement in patients with systemic sclerosis. DESIGN:Retrospective review of esophageal motility, esophageal pH, and pulmonary function data. SETTING:University hospital outpatient clinic and community. PATIENTS:3...

journal_title：Annals of internal medicine

authors： Troshinsky MB,Kane GC,Varga J,Cater JR,Fish JE,Jimenez SA,Castell DO

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To compare generalists' and cardiologists' estimates of baseline cardiovascular risk and the outcomes of preventive therapy. DESIGN:Cross-sectional mail survey using written case simulations of typical patients from primary prevention trials for hypercholesterolemia and isolated systolic hypertension, and te...

journal_title：Annals of internal medicine

authors： Friedmann PD,Brett AS,Mayo-Smith MF

更新日期：1996-02-15 00:00:00

abstract：:Transitional care has been defined as a set of actions designed to ensure the coordination and continuity of health care as patients transfer between different locations or different levels of care in the same location. Transitional care, which primarily concerns the relatively brief time interval that begins with pre...

journal_title：Annals of internal medicine

authors： Coleman EA,Berenson RA

更新日期：2004-10-05 00:00:00

abstract：:Recent national recommendations have proposed that physicians should titrate lipid therapy to achieve low-density lipoprotein (LDL) cholesterol levels less than 1.81 mmol/L (<70 mg/dL) for patients at very high cardiovascular risk and less than 2.59 mmol/L (<100 mg/dL) for patients at high cardiovascular risk. To exam...

journal_title：Annals of internal medicine

authors： Hayward RA,Hofer TP,Vijan S

更新日期：2006-10-03 00:00:00

abstract：:Much of what is formally taught in medicine is about the knowledge, skills, and behaviors required of a physician, including how to express compassion and respect for patients at the bedside. What is learned, however, includes not only admirable qualities but also behaviors and qualities that are inconsistent with eth...

journal_title：Annals of internal medicine

authors： Lehmann LS,Sulmasy LS,Desai S,ACP Ethics, Professionalism and Human Rights Committee.

更新日期：2018-04-03 00:00:00

abstract：:Acute coronary syndromes--unstable angina, myocardial infarction, and sudden cardiac death--are caused by acute disruption of an unstable coronary atheroma. Unstable plaques have three histologic characteristics: a large lipid core, many inflammatory cells, and a thin fibrous cap. Because the unstable plaque is not ne...

journal_title：Annals of internal medicine

authors： Forrester JS

更新日期：2002-11-19 00:00:00

abstract：BACKGROUND:Several studies show an inverse association between self-reported physical activity and type 2 diabetes. It is not known whether physical activity or cardiorespiratory fitness is associated with the onset of objectively determined impaired fasting glucose and type 2 diabetes. OBJECTIVE:To determine whether ...

journal_title：Annals of internal medicine

authors： Wei M,Gibbons LW,Mitchell TL,Kampert JB,Lee CD,Blair SN

更新日期：1999-01-19 00:00:00

abstract：DESCRIPTION:Updated U.S. Preventive Services Task Force (USPSTF) recommendation about screening for type 2 diabetes mellitus in adults. METHODS:To estimate the balance of benefits and harms of screening, the USPSTF updated its 2003 evidence review, adding evidence from new trials as well as updates on earlier studies....

journal_title：Annals of internal medicine

authors： U.S. Preventive Services Task Force.

更新日期：2008-06-03 00:00:00

abstract：BACKGROUND:Home-based primary care for homebound seniors is complex, and practice constraints are unique. No quality-of-care standards exist. OBJECTIVE:To identify process quality indicators that are essential to high-quality, home-based primary care. DESIGN:An expert development panel reviewed established and new qu...

journal_title：Annals of internal medicine

authors： Smith KL,Soriano TA,Boal J

更新日期：2007-02-06 00:00:00

abstract：:This issue provides a clinical overview of Clostridium difficile infection focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits. Only ACP members and individual subscribers can access the electronic features of In th...

journal_title：Annals of internal medicine

authors： Hessen MT

更新日期：2010-10-05 00:00:00

abstract：:We isolated a high molecular weight antigen of the Legionnaires' disease (LD) bacterium by column chromatography. The antigen was composed of 35% carbohydrate, 2.6% protein, 1.8% phospholipid, and 1% 2-keto-3-deoxyoctonate and was important in the host's antibody response because it inhibited the indirect immunofluore...

journal_title：Annals of internal medicine

authors： Johnson W,Elliott JA,Helms CM,Renner ED

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:The National Kidney Foundation has advocated the use of the abbreviated Modification of Diet in Renal Disease (MDRD) equation to estimate glomerular filtration rate (GFR) from serum creatinine measurements in clinical laboratories. However, healthy persons were not included in the development of the MDRD equ...

journal_title：Annals of internal medicine

authors： Rule AD,Larson TS,Bergstralh EJ,Slezak JM,Jacobsen SJ,Cosio FG

更新日期：2004-12-21 00:00:00

abstract：:In an era of increasing competition in medical care, critical pathway guidelines have emerged as one of the most popular new initiatives intended to reduce costs while maintaining or even improving the quality of care. Developed primarily for high-volume hospital diagnoses, critical pathways display goals for patients...

journal_title：Annals of internal medicine

authors： Pearson SD,Goulart-Fisher D,Lee TH

更新日期：1995-12-15 00:00:00

abstract：SOURCE CITATION:Tsapas A, Avgerinos I, Karagiannis T, et al. Comparative effectiveness of glucose-lowering drugs for type 2 diabetes: a systematic review and network meta-analysis. Ann Intern Med. 2020;173:278-86. 32598218. ...

journal_title：Annals of internal medicine

authors： Gandhi GY

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:Valid measurement of physician performance requires accurate identification of patients for whom a physician is responsible. Among all patients seen by a physician, some will be more strongly connected to their physician than others, but the effect of connectedness on measures of physician performance is not...

journal_title：Annals of internal medicine

authors： Atlas SJ,Grant RW,Ferris TG,Chang Y,Barry MJ

更新日期：2009-03-03 00:00:00

abstract：BACKGROUND:It has been reported that walnuts reduce serum cholesterol levels in normal young men. OBJECTIVE:To assess the acceptability of walnuts and their effects on serum lipid levels and low-density lipoprotein (LDL) oxidizability in free-living hypercholesterolemic persons. DESIGN:Randomized, crossover feeding t...

journal_title：Annals of internal medicine

authors： Zambón D,Sabaté J,Muñoz S,Campero B,Casals E,Merlos M,Laguna JC,Ros E

更新日期：2000-04-04 00:00:00

abstract：:Polysaccharide vaccines against diseases caused by Neisseria meningitidis serogroups A and C meningococci are now licensed in the United States. They are prepared as monovalent and as bivalent antigens. This statement summarizes available information on these antigen and offers guidance regarding their role in the con...

journal_title：Annals of internal medicine

authors：

更新日期：1976-02-01 00:00:00