Graduate primary care training: a collaborative alternative for family practice, internal medicine, and pediatrics.

abstract：:A 53-year-old librarian had recurrent palpable purpura on her ankles and legs that was found to be caused by the fumes released from heat-activated photocopy paper at her place of employment. Behenic acid was identified as the responsible chemical component through a series of challenge studies that simulated her work...

journal_title：Annals of internal medicine

authors： Tencati JR,Novey HS

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND:The incidence of esophageal adenocarcinoma is increasing rapidly. Gastroesophageal reflux is a strong risk factor for this disease. The increase in incidence of esophageal adenocarcinoma coincided with the introduction of medications that promote reflux by relaxing the lower esophageal sphincter (LES), such ...

journal_title：Annals of internal medicine

authors： Lagergren J,Bergström R,Adami HO,Nyrén O

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Timely diagnosis of influenza can help clinical management. PURPOSE:To examine the accuracy of rapid influenza diagnostic tests (RIDTs) in adults and children with influenza-like illness and evaluate factors associated with higher accuracy. DATA SOURCES:PubMed and EMBASE through December 2011; BIOSIS and W...

journal_title：Annals of internal medicine

authors： Chartrand C,Leeflang MM,Minion J,Brewer T,Pai M

更新日期：2012-04-03 00:00:00

abstract：OBJECTIVE:To critically evaluate the evidence for recommending the screening of asymptomatic men for prostate cancer with a blood test to detect a prostate-specific antigen (PSA). DATA SOURCES:Relevant articles on screening for prostate cancer were identified from MEDLINE searches, from the authors' files, and from th...

journal_title：Annals of internal medicine

authors： Kramer BS,Brown ML,Prorok PC,Potosky AL,Gohagan JK

更新日期：1993-11-01 00:00:00

abstract：:Conventional interpretation of clinical trials relies heavily on the classic p value. The p value, however, represents only a false-positive rate, and does not tell the probability that the investigator's hypothesis is correct, given his observations. This more relevant posterior probability can be quantified by an ex...

journal_title：Annals of internal medicine

authors： Diamond GA,Forrester JS

更新日期：1983-03-01 00:00:00

abstract：:Simulation is a versatile technique used in a variety of health care settings for a variety of purposes, but the extent to which simulation may improve patient safety remains unknown. This systematic review examined evidence on the effects of simulation techniques on patient safety outcomes. PubMed and the Cochrane Li...

journal_title：Annals of internal medicine

authors： Schmidt E,Goldhaber-Fiebert SN,Ho LA,McDonald KM

更新日期：2013-03-05 00:00:00

abstract：:Meningitis caused by enteric gram-negative bacilli is relatively uncommon but is very difficult to treat despite susceptibility in vitro to many antimicrobics. A major problem appears to be poor entry of many drugs into the central nervous system. Moxalactam is an investigational cephalosporin that attains concentrati...

journal_title：Annals of internal medicine

authors： Olson DA,Hoeprich PD,Nolan SM,Goldstein E

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Adiponectin and resistin are recently discovered adipokines that may provide a molecular link between adiposity and type 2 diabetes. OBJECTIVE:To evaluate whether total and high-molecular-weight adiponectin and resistin are associated with future risk for type 2 diabetes, independent of obesity and other kn...

journal_title：Annals of internal medicine

authors： Heidemann C,Sun Q,van Dam RM,Meigs JB,Zhang C,Tworoger SS,Mantzoros CS,Hu FB

更新日期：2008-09-02 00:00:00

abstract：OBJECTIVE:To evaluate the amount of variation in in-hospital mortality and length of intensive care unit (ICU) stay that can be accounted for by clinical data available at ICU admission. DESIGN:Inception cohort study. SETTING:Forty-two ICUs in 40 hospitals, including 26 hospitals that were randomly selected and 14 la...

journal_title：Annals of internal medicine

authors： Knaus WA,Wagner DP,Zimmerman JE,Draper EA

更新日期：1993-05-15 00:00:00

abstract：:Three patients with advanced Graves' ophthalmopathy were treated with cyclophosphamide. All had proptosis and diplopia. One patient had disabling iatrogenic Cushing's syndrome from steroid treatment of the ophthalmopathy and had undergone bilateral orbital decompression before cyclophosphamide therapy; steroids could ...

journal_title：Annals of internal medicine

authors： Bigos ST,Nisula BC,Daniels GH,Eastman RC,Johnston HH,Kohler PO

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Because clinical diagnosis is inaccurate, objective testing is usually considered necessary when patients present with suspected deep venous thrombosis (DVT). OBJECTIVE:To determine whether a negative result on a quantitative latex D dimer assay eliminates the need for further investigation in patients with...

journal_title：Annals of internal medicine

authors： Bates SM,Kearon C,Crowther M,Linkins L,O'Donnell M,Douketis J,Lee AY,Weitz JI,Johnston M,Ginsberg JS

更新日期：2003-05-20 00:00:00

abstract：:Aspirin exerts antiplatelet effects through irreversible inhibition of cyclooxygenase-1, whereas its anticancer effects may be due to inhibition of cyclooxygenase-2 and other pathways. In 2009, the U.S. Preventive Services Task Force endorsed aspirin for primary prevention of cardiovascular disease. However, aspirin's...

journal_title：Annals of internal medicine

authors： Burns RB,Graham K,Sawhney MS,Reynolds EE

更新日期：2017-12-05 00:00:00

abstract：BACKGROUND:Estimates of risk for radiation-induced breast cancer from mammography screening have not considered variation in dose exposure or diagnostic work-up after abnormal screening results. OBJECTIVE:To estimate distributions of radiation-induced breast cancer incidence and mortality from digital mammography scre...

journal_title：Annals of internal medicine

authors： Miglioretti DL,Lange J,van den Broek JJ,Lee CI,van Ravesteyn NT,Ritley D,Kerlikowske K,Fenton JJ,Melnikow J,de Koning HJ,Hubbard RA

更新日期：2016-02-16 00:00:00

abstract：:Bulimarexia, an eating disorder that is characterized by binge eating followed by self-induced vomiting or abuse of cathartic or diuretic drugs, has been defined as both a sequela of anorexia nervosa and a distinct eating disorder. In this review the presentation, prevalence, and complications of the various eating di...

journal_title：Annals of internal medicine

authors： Harris RT

更新日期：1983-12-01 00:00:00

abstract：:Clinicians can use data to improve daily clinical practice. This paper offers eight principles for using data to support improvement in busy clinical settings: 1) seek usefulness, not perfection, in the measurement; 2) use a balanced set of process, outcome, and cost measures; 3) keep measurement simple (think big, bu...

journal_title：Annals of internal medicine

authors： Nelson EC,Splaine ME,Batalden PB,Plume SK

更新日期：1998-03-15 00:00:00

abstract：:To re-evaluate the relationship between Crohn's disease and sarcoidosis, we compared the numbers and types of cells recovered by bronchoalveolar lavage from normal volunteers and patients with Crohn's disease, with other forms of inflammatory bowel disease, and with sarcoidosis. Patients with Crohn's disease, but not ...

journal_title：Annals of internal medicine

authors： Smiéjan JM,Cosnes J,Chollet-Martin S,Soler P,Basset FM,Le Quintrec Y,Hance AJ

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Elevated blood pressure (BP) is the largest contributing risk factor to all-cause and cardiovascular mortality. PURPOSE:To update a systematic review on the benefits and harms of screening for high BP in adults and to summarize evidence on rescreening intervals and diagnostic and predictive accuracy of diff...

journal_title：Annals of internal medicine

authors： Piper MA,Evans CV,Burda BU,Margolis KL,O'Connor E,Whitlock EP

更新日期：2015-02-03 00:00:00

abstract：:The content, role, and purpose of internal medicine, organized as an American specialty 100 years ago, have been marked by ambivalence from the beginning. Nevertheless, molded to a large extent by external events, including the strategic and symbolic importance of surgery in American medicine, the rise of university m...

journal_title：Annals of internal medicine

authors： Stevens R

更新日期：1986-10-01 00:00:00

abstract：PURPOSE:It is currently unknown whether intensive insulin treatment of diabetes decreases the risk for cardiovascular complications by lowering glucose levels or increases the risk by postulated direct atherogenic effects. This article reviews published data from two long-term, randomized clinical trials that compared ...

journal_title：Annals of internal medicine

authors： Genuth S

更新日期：1996-01-01 00:00:00

abstract：:Restrictive cardiomyopathy produced by primary cardiac amyloidosis may have a clinical syndrome identical to noncalcific constrictive pericarditis. We report two patients with amyloidosis and restrictive physiology who had enlarged papillary muscles shown on left ventricular angiocardiogram. Rapid volume expansion wit...

journal_title：Annals of internal medicine

authors： Maule WF,Martin RH

更新日期：1983-02-01 00:00:00

abstract：:Flecainide acetate has a recognized proarrhythmic effect in patients treated for ventricular tachycardia. Three patients developed severe ventricular arrhythmias while taking flecainide for atrial fibrillation. Patient 1 had normal ventricular function and idiopathic atrial fibrillation. Treadmill exercise tests durin...

journal_title：Annals of internal medicine

authors： Falk RH

更新日期：1989-07-15 00:00:00

abstract：:The competition for funds to conduct clinical research is intense, and only a minority of grant proposals receive funding. In particular, funding for patient-oriented research lags behind that allocated for basic science research. Grant writing is a skill of fundamental importance to the clinical researcher, and condu...

journal_title：Annals of internal medicine

authors： Inouye SK,Fiellin DA

更新日期：2005-02-15 00:00:00

abstract：BACKGROUND:The coronavirus disease 2019 (COVID-19) pandemic continues to surge in the United States and globally. OBJECTIVE:To describe the epidemiology of COVID-19-related critical illness, including trends in outcomes and care delivery. DESIGN:Single-health system, multihospital retrospective cohort study. SETTING...

journal_title：Annals of internal medicine

authors： Anesi GL,Jablonski J,Harhay MO,Atkins JH,Bajaj J,Baston C,Brennan PJ,Candeloro CL,Catalano LM,Cereda MF,Chandler JM,Christie JD,Collins T,Courtright KR,Fuchs BD,Gordon E,Greenwood JC,Gudowski S,Hanish A,Hanson Iii C

更新日期：2021-01-19 00:00:00

abstract：:Clinical features of 99 patients with staphylococcal infection were reviewed, and sera were tested by solid-phase radioimmunoassay and gel diffusion for staphylococcal antibodies to ascertain whether these variables predict the extent of infection and the need for prolonged therapy. Clinical features, including the pr...

journal_title：Annals of internal medicine

authors： Wheat LJ,Kohler RB,White A

更新日期：1978-10-01 00:00:00

abstract：OBJECTIVE:To determine the relations among esophageal dysfunction, gastroesophageal reflux, and lung involvement in patients with systemic sclerosis. DESIGN:Retrospective review of esophageal motility, esophageal pH, and pulmonary function data. SETTING:University hospital outpatient clinic and community. PATIENTS:3...

journal_title：Annals of internal medicine

authors： Troshinsky MB,Kane GC,Varga J,Cater JR,Fish JE,Jimenez SA,Castell DO

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To determine, through structured methodologic review of published articles, the effectiveness of short-course (< or = 2 weeks) antibiotic therapy for catheter-related Staphylococcus aureus bacteremia. DATA SOURCES:English-language publications on catheter-related S. aureus bacteremia identified using MEDLINE...

journal_title：Annals of internal medicine

authors： Jernigan JA,Farr BM

更新日期：1993-08-15 00:00:00

abstract：:Traditionally, acupuncture is embedded in naturalistic theories that are compatible with Confucianism and Taoism. Such ideas as yin-yang, qi, dampness, and wind represent East Asian conceptual frameworks that emphasize the reliability of ordinary, human sensory awareness. Many physicians who practice acupuncture rejec...

journal_title：Annals of internal medicine

authors： Kaptchuk TJ

更新日期：2002-03-05 00:00:00

abstract：OBJECTIVE:To develop criteria for interpreting results of the metyrapone test for the differential diagnosis of the adrenocorticotropin (ACTH)-dependent Cushing syndrome and to compare its diagnostic accuracy with that of the high-dose dexamethasone suppression test. DESIGN:Retrospective cohort study. SETTING:Inpatie...

journal_title：Annals of internal medicine

authors： Avgerinos PC,Yanovski JA,Oldfield EH,Nieman LK,Cutler GB Jr

更新日期：1994-09-01 00:00:00

abstract：OBJECTIVE:To describe 13 infections caused by Mycobacterium haemophilum. DESIGN:Identification of patients by microbiologic record review, followed by medical record review and a case-control study. SETTING:Seven metropolitan hospitals in New York. PATIENTS:All patients with M. haemophilum infections diagnosed betwe...

journal_title：Annals of internal medicine

authors： Straus WL,Ostroff SM,Jernigan DB,Kiehn TE,Sordillo EM,Armstrong D,Boone N,Schneider N,Kilburn JO,Silcox VA,LaBombardi V,Good RC

更新日期：1994-01-15 00:00:00

abstract：:Opioid dependence is a chronic relapsing medical condition with substantial health and societal complications. Recent federal initiatives are designed to enhance the medical treatment of patients with opioid dependence and will expand the role of internists in the care of these patients. These initiatives include a pr...

journal_title：Annals of internal medicine

authors： Fiellin DA,O'Connor PG

更新日期：2002-10-15 00:00:00