Osteomalacia: current concepts.

abstract：:We recently implemented a full-featured electronic health record in our independent, 4-internist, community-based practice of general internal medicine. We encountered various challenges, some unexpected, in moving from paper to computer. This article describes the effects that use of electronic health records has had...

journal_title：Annals of internal medicine

authors： Baron RJ,Fabens EL,Schiffman M,Wolf E

更新日期：2005-08-02 00:00:00

abstract：:We studied renal plasma flow and glomerular filtration rate during graded blood pressure reduction induced with sodium nitroprusside infusion in 16 hypertensive patients with atherosclerotic renovascular disease. Eight patients with unilateral disease tolerated pressure reduction from 205 +/- 9 (SE)/103 +/- 2 mm Hg to...

journal_title：Annals of internal medicine

authors： Textor SC,Novick AC,Tarazi RC,Klimas V,Vidt DG,Pohl M

更新日期：1985-03-01 00:00:00

abstract：:The indications for treating patients with subclinical hypothyroidism (normal serum thyroxine and free thyroxine levels, but elevated serum thyrotrophin levels) are poorly defined. In this study, 33 patients with subclinical hypothyroidism were randomly assigned in a double-blind manner to receive placebo or L-thyroxi...

journal_title：Annals of internal medicine

authors： Cooper DS,Halpern R,Wood LC,Levin AA,Ridgway EC

更新日期：1984-07-01 00:00:00

abstract：:Studies of circulating T- and B-lymphocyte rosettes were done in 20 healthy controls and 29 patients with pulmonary tuberculosis, including 18 receiving rifampin chemotherapy. Eight of the 18 patients in the rifampin group (44%) had significant suppression of their T-cell rosettes as compared with patients with tuberc...

journal_title：Annals of internal medicine

authors： Gupta S,Grieco MH,Siegel I

更新日期：1975-04-01 00:00:00

abstract：:Despite some impressive recent gains, improving the glaring deficiencies in health care quality is proving to be very hard. Improvement is local, rather than system-wide, and is sustained with difficulty, rather than becoming an intrinsic feature of care. My right knee will probably need to be replaced soon. This has ...

journal_title：Annals of internal medicine

authors： Berwick DM

更新日期：2005-01-18 00:00:00

abstract：BACKGROUND:Opioids are frequently prescribed for acute musculoskeletal injuries and may result in long-term use and consequent harms. PURPOSE:To explore factors associated with persistent opioid use after its prescription for acute musculoskeletal injury. DATA SOURCES:Searches of multiple electronic databases, withou...

journal_title：Annals of internal medicine

authors： Riva JJ,Noor ST,Wang L,Ashoorion V,Foroutan F,Sadeghirad B,Couban R,Busse JW

更新日期：2020-11-03 00:00:00

abstract：Background:Acute pancreatitis (AP) varies in severity, prompting development of systems aimed at predicting prognosis to help guide therapy. Although several prediction approaches are available, their test characteristics and clinical utility are not completely understood. Purpose:To evaluate the test characteristics ...

journal_title：Annals of internal medicine

authors： Di MY,Liu H,Yang ZY,Bonis PA,Tang JL,Lau J

更新日期：2016-10-04 00:00:00

abstract：PURPOSE:To review the available data on the treatment of chronic stable angina and formulate a rational approach to the use of pharmacologic therapy, percutaneous transluminal coronary angioplasty (PTCA), and coronary artery bypass graft surgery (CABG). DATA SOURCES:A MEDLINE search of English-language literature publ...

journal_title：Annals of internal medicine

authors： Solomon AJ,Gersh BJ

更新日期：1998-02-01 00:00:00

abstract：:Acute coronary syndromes--unstable angina, myocardial infarction, and sudden cardiac death--are caused by acute disruption of an unstable coronary atheroma. Unstable plaques have three histologic characteristics: a large lipid core, many inflammatory cells, and a thin fibrous cap. Because the unstable plaque is not ne...

journal_title：Annals of internal medicine

authors： Forrester JS

更新日期：2002-11-19 00:00:00

abstract：:Of 5379 patients who had received radiation treatment at our institution for benign conditions of the head and neck, 318 developed thyroid cancer 3 to 42 years later. We report follow-up observations (median interval from diagnosis to recurrence or last contact, 10 years; longest interval, 31) for 296 of these patient...

journal_title：Annals of internal medicine

authors： Schneider AB,Recant W,Pinsky SM,Ryo UY,Bekerman C,Shore-Freedman E

更新日期：1986-09-01 00:00:00

abstract：STUDY OBJECTIVE:To critically assess original studies evaluating the role of preoperative pulmonary function testing in predicting postoperative outcomes. DESIGN:MEDLINE search of English-language articles from 1966 to 1987 using the following medical subjects headings respiratory function tests, lung, lung diseases, ...

journal_title：Annals of internal medicine

authors： Zibrak JD,O'Donnell CR,Marton K

更新日期：1990-05-15 00:00:00

abstract：BACKGROUND:Although the efficacy of adjuvant chemotherapy in prolonging survival for women with breast cancer has been well documented, limited population-based information is available on the actual use of chemotherapy. OBJECTIVE:To examine the relationship between age and chemotherapy use. DESIGN:Cohort study. SET...

journal_title：Annals of internal medicine

authors： Du XL,Key CR,Osborne C,Mahnken JD,Goodwin JS

更新日期：2003-01-21 00:00:00

abstract：:In deciding whether to undertake a dietary program to reduce serum cholesterol levels, a person must consider how much benefit to expect. We developed a model that assumes cholesterol reduction is effective and safe in reducing the risk for death from ischemic heart disease. In the model, we considered asymptomatic ad...

journal_title：Annals of internal medicine

authors： Taylor WC,Pass TM,Shepard DS,Komaroff AL

更新日期：1987-04-01 00:00:00

abstract：:Clinical features of 99 patients with staphylococcal infection were reviewed, and sera were tested by solid-phase radioimmunoassay and gel diffusion for staphylococcal antibodies to ascertain whether these variables predict the extent of infection and the need for prolonged therapy. Clinical features, including the pr...

journal_title：Annals of internal medicine

authors： Wheat LJ,Kohler RB,White A

更新日期：1978-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the amount of variation in in-hospital mortality and length of intensive care unit (ICU) stay that can be accounted for by clinical data available at ICU admission. DESIGN:Inception cohort study. SETTING:Forty-two ICUs in 40 hospitals, including 26 hospitals that were randomly selected and 14 la...

journal_title：Annals of internal medicine

authors： Knaus WA,Wagner DP,Zimmerman JE,Draper EA

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:Leukotriene-receptor antagonists (LTRAs) are recommended as an alternative treatment in patients with mild asthma, but their effect compared with placebo is unclear. PURPOSE:To determine the benefits and harms of LTRAs as monotherapy or in combination with inhaled corticosteroids compared with placebo in ad...

journal_title：Annals of internal medicine

authors： Miligkos M,Bannuru RR,Alkofide H,Kher SR,Schmid CH,Balk EM

更新日期：2015-11-17 00:00:00

abstract：Background:Probiotics, prebiotics, and synbiotics are used increasingly, although the safety and potential harms of these interventions are poorly understood. Purpose:To examine how harms-related information is reported in publications of randomized controlled trials (RCTs) of probiotics, prebiotics, and synbiotics. ...

journal_title：Annals of internal medicine

authors： Bafeta A,Koh M,Riveros C,Ravaud P

更新日期：2018-08-21 00:00:00

abstract：STUDY OBJECTIVE:To assess the effects of dopamine, which has an inotropic effect on the myocardium and increases renal and splanchnic blood flow, on diaphragmatic contraction. DESIGN AND PATIENTS:We studied the changes in transdiaphragmatic pressure during electrical bilateral supramaximal stimulation of the phrenic n...

journal_title：Annals of internal medicine

authors： Aubier M,Murciano D,Menu Y,Boczkowski J,Mal H,Pariente R

更新日期：1989-01-01 00:00:00

abstract：:The four main conceptual paradigms of basic biomedical research are that the explication of mechanisms is a primary goal of science; that scientific data must be "hard"; that formulation of hypotheses and counter-hypotheses is a principal creative challenge; and that experiments are the main mechanism for using scient...

journal_title：Annals of internal medicine

authors： Feinstein AR

更新日期：1983-09-01 00:00:00

abstract：Background:Central line-associated bloodstream infection (CLABSI) remains prevalent in hospitals in the United States. Objective:To evaluate the impact of a multimodal intervention in hospitals with elevated rates of health care-associated infection. Design:Pre-post observational evaluation of a prospective, national...

journal_title：Annals of internal medicine

authors： Patel PK,Greene MT,Jones K,Rolle AJ,Ratz D,Snyder A,Saint S,Chopra V

更新日期：2019-10-01 00:00:00

abstract：:Myocardial infarction was diagnosed in 431 (30%) of 1460 patients with acute chest pain who had serial enzyme testing after admission to intensive or intermediate care units at three teaching and three community hospitals. The diagnosis was made within 12 hours of admission in 331 (77%) patients and within 24 hours in...

journal_title：Annals of internal medicine

authors： Lee TH,Rouan GW,Weisberg MC,Brand DA,Cook EF,Acampora D,Goldman L

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:The number of very elderly persons who are candidates for implantation of a permanent pacemaker is increasing, but the effect of cardiac pacing on long-term survival and functional variables has not been determined. OBJECTIVE:To determine long-term survival after implantation of a permanent pacemaker in oct...

journal_title：Annals of internal medicine

authors： Shen WK,Hayes DL,Hammill SC,Bailey KR,Ballard DJ,Gersh BJ

更新日期：1996-09-15 00:00:00

abstract：:This issue provides a clinical overview of Clostridium difficile infection focusing on prevention, diagnosis, treatment, practice improvement, and patient information. Readers can complete the accompanying CME quiz for 1.5 credits. Only ACP members and individual subscribers can access the electronic features of In th...

journal_title：Annals of internal medicine

authors： Hessen MT

更新日期：2010-10-05 00:00:00

abstract：Background:Bone health is a significant concern in men with prostate cancer. Purpose:To evaluate the effectiveness of drug, supplement, and lifestyle interventions aimed at preventing fracture, improving bone mineral density (BMD), or preventing or delaying osteoporosis in men with nonmetastatic prostate cancer. Data...

journal_title：Annals of internal medicine

authors： Alibhai SMH,Zukotynski K,Walker-Dilks C,Emmenegger U,Finelli A,Morgan SC,Hotte SJ,Tomlinson GA,Winquist E

更新日期：2017-09-05 00:00:00

abstract：:The syndrome of bulimia is a common disorder and can be associated with serious psychological and physical morbidity. Unfortunately, many patients are reluctant to discuss their symptoms with their physicians and few clues can be found on physical examination to aid in the diagnosis. Possible physical signs include ul...

journal_title：Annals of internal medicine

authors： Mitchell JE,Seim HC,Colon E,Pomeroy C

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:Ulcerative colitis is predominantly a disease of nonsmokers. Transdermal nicotine may help control clinical manifestations of this condition. OBJECTIVE:To determine the efficacy of transdermal nicotine for controlling clinical disease activity in active ulcerative colitis. DESIGN:Randomized, double-blind, ...

journal_title：Annals of internal medicine

authors： Sandborn WJ,Tremaine WJ,Offord KP,Lawson GM,Petersen BT,Batts KP,Croghan IT,Dale LC,Schroeder DR,Hurt RD

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Injection insulin therapy is not readily accepted by patients and many health care providers; therefore, less invasive options for insulin therapy are desirable. PURPOSE:To examine the efficacy, safety, and patient acceptability of inhaled insulin therapy in nonpregnant adults with diabetes mellitus. DATA ...

journal_title：Annals of internal medicine

authors： Ceglia L,Lau J,Pittas AG

更新日期：2006-11-07 00:00:00

abstract：:Discovery of the factor V Leiden and prothrombin G20210A mutations has greatly increased the percentage of patients in whom venous thrombosis can be attributed to hereditary thrombophilia. The first step in the diagnostic approach to all patients with venous thrombosis consists of a careful history and physical examin...

journal_title：Annals of internal medicine

authors： Bauer KA

更新日期：2001-09-04 00:00:00

abstract：:Behavior modification applied to the treatment of obesity has evolved from the environmental control of eating behavior to a broader approach characterized by systematic manipulation of all factors associated with eating and exercise patterns. This approach has shown success in helping obese persons lose modest amount...

journal_title：Annals of internal medicine

authors： Foreyt JP,Goodrick GK

更新日期：1993-10-01 00:00:00

abstract：:Patients with diabetes mellitus and coronary artery disease are thought to have painless myocardial ischemia more often than patients without diabetes. We studied 50 consecutive patients with diabetes and 50 consecutive patients without diabetes, all with ischemia, on exercise thallium scintigraphy to show the reliabi...

journal_title：Annals of internal medicine

authors： Nesto RW,Phillips RT,Kett KG,Hill T,Perper E,Young E,Leland OS Jr

更新日期：1988-02-01 00:00:00