Angina and exertional myocardial ischemia in diabetic and nondiabetic patients: assessment by exercise thallium scintigraphy.

abstract：:Population screening for hemochromatosis done by using the transferrin saturation test has been advocated by experts to permit the initiation of therapeutic phlebotomy before the onset of clinical disease. The discovery of a gene associated with hemochromatosis has made DNA testing another option for screening and dia...

journal_title：Annals of internal medicine

authors： Cogswell ME,McDonnell SM,Khoury MJ,Franks AL,Burke W,Brittenham G

更新日期：1998-12-01 00:00:00

abstract：:9-(1,3-dihydroxy-2-propoxymethyl) guanine (ganciclovir) was used to treat 41 patients (median age, 37 years) with the acquired immunodeficiency syndrome and cytomegalovirus gastrointestinal infection. Sites of infection were the colon in 31, the esophagus in 5, the rectum in 4, and the small bowel in 1. Patients recei...

journal_title：Annals of internal medicine

authors： Chachoua A,Dieterich D,Krasinski K,Greene J,Laubenstein L,Wernz J,Buhles W,Koretz S

更新日期：1987-08-01 00:00:00

abstract：:Increasingly, interventions aimed at improving care are likely to use such technologies as machine learning and artificial intelligence. However, health care has been relatively late to adopt them. This article provides clinical examples in which machine learning and artificial intelligence are already in use in healt...

journal_title：Annals of internal medicine

authors： Bates DW,Auerbach A,Schulam P,Wright A,Saria S

更新日期：2020-06-02 00:00:00

abstract：BACKGROUND:No effective oral therapy exists for early coronavirus disease 2019 (COVID-19). OBJECTIVE:To investigate whether hydroxychloroquine could reduce COVID-19 severity in adult outpatients. DESIGN:Randomized, double-blind, placebo-controlled trial conducted from 22 March through 20 May 2020. (ClinicalTrials.gov...

journal_title：Annals of internal medicine

authors： Skipper CP,Pastick KA,Engen NW,Bangdiwala AS,Abassi M,Lofgren SM,Williams DA,Okafor EC,Pullen MF,Nicol MR,Nascene AA,Hullsiek KH,Cheng MP,Luke D,Lother SA,MacKenzie LJ,Drobot G,Kelly LE,Schwartz IS,Zarychanski R,M

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Home-based primary care for homebound seniors is complex, and practice constraints are unique. No quality-of-care standards exist. OBJECTIVE:To identify process quality indicators that are essential to high-quality, home-based primary care. DESIGN:An expert development panel reviewed established and new qu...

journal_title：Annals of internal medicine

authors： Smith KL,Soriano TA,Boal J

更新日期：2007-02-06 00:00:00

abstract：BACKGROUND:Urine tests for Chlamydia trachomatis permit expansion of screening beyond traditional clinic environments. Prevention of infection in teenagers is a high priority. OBJECTIVE:To define the prevalence of C. trachomatis among teenagers by using the ligase chain reaction assay on urine specimens and to evaluat...

journal_title：Annals of internal medicine

authors： Marrazzo JM,White CL,Krekeler B,Celum CL,Lafferty WE,Stamm WE,Handsfield HH

更新日期：1997-11-01 00:00:00

abstract：STUDY OBJECTIVE:To determine the efficacy of continuous intravenous infusion of prostacyclin (epoprostenol) in primary pulmonary hypertension. DESIGN:Randomized trial with 8-week treatment periods and nonrandomized treatment for up to 18 months. SETTING:Four referral centers. PATIENTS:Sequential sample of 24 patient...

journal_title：Annals of internal medicine

authors： Rubin LJ,Mendoza J,Hood M,McGoon M,Barst R,Williams WB,Diehl JH,Crow J,Long W

更新日期：1990-04-01 00:00:00

abstract：:Medical school graduates are avoiding primary care. The very aspects that once attracted students have been subverted. The breadth of practice that was once appealing has become the breadth of heavy-handed scrutiny, as politicians and business leaders have demanded quality--simplistically defined as dogmatic adherence...

journal_title：Annals of internal medicine

authors： Norenberg DD

更新日期：2009-05-19 00:00:00

abstract：:Medical devices have become an integral part of hospital-based care but also predispose patients to more than 850 000 device-related infections annually. Devices predispose to infection by damaging or invading epithelial and mucosal barriers to infection, by supporting growth of microorganisms and thus serving as rese...

journal_title：Annals of internal medicine

authors： Stamm WE

更新日期：1978-11-01 00:00:00

abstract：:Impairment of penicillin G excretion in renal failure may result in life-threatening, dose-related toxicity. We report a method for achieving a desired mean serum penicillin G concentration in patients with renal failure, with minimal risk of both undertreatment and drug toxicity. The method is based on the linear rel...

journal_title：Annals of internal medicine

authors： Bryan CS,Stone WJ

更新日期：1975-02-01 00:00:00

abstract：:During a 6-month period in 1983, Escherichia coli O157:H7 was isolated from 19 (15%) of 125 patients with grossly bloody diarrhea and 1 sibling with non-bloody diarrhea in the Calgary area. There was no clustering of the cases geographically or in time. All but 1 had clinical manifestations typical of hemorrhagic coli...

journal_title：Annals of internal medicine

authors： Pai CH,Gordon R,Sims HV,Bryan LE

更新日期：1984-12-01 00:00:00

abstract：:Recent research on human macrophage activation has reemphasized the critical role of the lymphokine-secreting T cell in converting quiescent macrophages to efficient microbicidal phagocytes. Interferon-gamma, a key lymphokine secreted by antigen-triggered T4+ helper cells, is capable of inducing the macrophage to act ...

journal_title：Annals of internal medicine

authors： Murray HW

更新日期：1988-04-01 00:00:00

abstract：Background:The 2013 cholesterol management guidelines from the American College of Cardiology and American Heart Association (ACC/AHA) recommend lipid screening in all adults older than 20 years to identify those at increased risk for atherosclerotic cardiovascular disease (ASCVD). Statins may be considered for patient...

journal_title：Annals of internal medicine

authors： Patel KK,Taksler GB,Hu B,Rothberg MB

更新日期：2017-06-20 00:00:00

abstract：OBJECTIVE:To determine whether prolonging the duration of tamoxifen administration beyond the cessation of a combined chemotherapy regimen benefits patients with primary breast cancer with positive findings in axillary nodes who benefit initially from the combined regimen. DESIGN:Nonrandomized, nonconcurrent cohort st...

journal_title：Annals of internal medicine

authors： Fisher B,Brown A,Wolmark N,Redmond C,Wickerham DL,Wittliff J,Dimitrov N,Legault-Poisson S,Schipper H,Prager D

更新日期：1987-05-01 00:00:00

abstract：:A case of a patient with metastatic cancer raises the issues of patient refusal of treatment, euthanasia, and unintended side effects of therapy. For each management dilemma, there are relevant ethical and legal considerations, justifications, and conclusions. In addition, psychological and social influences on the de...

journal_title：Annals of internal medicine

authors： Lo B,Jonsen AR

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:The risk for venous thromboembolism during pregnancy or postpartum is uncertain. OBJECTIVES:To estimate the relative and absolute risk for deep venous thrombosis and pulmonary embolism during pregnancy and postpartum and to describe trends in incidence. DESIGN:Population-based inception cohort study using ...

journal_title：Annals of internal medicine

authors： Heit JA,Kobbervig CE,James AH,Petterson TM,Bailey KR,Melton LJ 3rd

更新日期：2005-11-15 00:00:00

abstract：:An unusual cluster of 11 patients with Pneumocystis carinii pneumonia occurred in a 3-month period at Memorial Hospital, New York. Ten of the 11 patients had lymphoma or leukemia. In 7 patients, corticosteroid therapy was decreased or stopped shortly before pneumocystis pneumonia was diagnosed. The pediatric patients ...

journal_title：Annals of internal medicine

authors： Singer C,Armstrong D,Rosen PP,Schottenfeld D

更新日期：1975-06-01 00:00:00

abstract：:Disturbances of urinary bladder function are well-recognized problems in diabetic patients and are generally attributed to peripheral neuropathy. Because of the difficulties inherent in the histologic examination of the peripheral autonomic nerves, little is known about the pathology of these nerves. Recently, alterat...

journal_title：Annals of internal medicine

authors： Mastri AR

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Vertebral fractures are a hallmark of postmenopausal osteoporosis and an important end point in trials of osteoporosis treatment, but the clinical significance of these fractures remains uncertain. OBJECTIVE:To determine the association of new vertebral fractures with back pain and back-related functional l...

journal_title：Annals of internal medicine

authors： Nevitt MC,Ettinger B,Black DM,Stone K,Jamal SA,Ensrud K,Segal M,Genant HK,Cummings SR

更新日期：1998-05-15 00:00:00

abstract：:Bacteremia caused by rapidly growing mycobacteria are usually due to Mycobacterium fortuitum or M. chelonei. Other rapidly growing mycobacteria generally are considered to be nonpathogenic. We report the case of a patient with bacteremia due to an unidentified, rapidly growing, scotochromogenic mycobacteria that was d...

journal_title：Annals of internal medicine

authors： Jadeja L,Bolivar R,Wallace RJ Jr,Silcox VA,Bodey GP

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that patients hospitalized with acute myocardial infarction (MI) in December have poor outcomes, and some studies have hypothesized that the cause may be the infrequent use of evidence-based therapies during the December holiday season. OBJECTIVE:To compare the care and outcomes of ...

journal_title：Annals of internal medicine

authors： Meine TJ,Patel MR,DePuy V,Curtis LH,Rao SV,Gersh BJ,Schulman KA,Jollis JG

更新日期：2005-10-04 00:00:00

abstract：:The following principles of appropriate antibiotic use for adults with acute pharyngitis apply to immunocompetent adults without complicated comorbid conditions, such as chronic lung or heart disease, and history of rheumatic fever. They do not apply during known outbreaks of group A streptococcus.1. Group A beta-hemo...

journal_title：Annals of internal medicine

authors： Cooper RJ,Hoffman JR,Bartlett JG,Besser RE,Gonzales R,Hickner JM,Sande MA,American Academy of Family Physicians.,American College of Physicians-American Society of Internal Medicine.,Centers for Disease Control.

更新日期：2001-03-20 00:00:00

abstract：BACKGROUND:The paucity of public health messages that directly address communities of color might contribute to racial and ethnic disparities in knowledge and behavior related to coronavirus disease 2019 (COVID-19). OBJECTIVE:To determine whether physician-delivered prevention messages affect knowledge and information...

journal_title：Annals of internal medicine

authors： Alsan M,Stanford FC,Banerjee A,Breza E,Chandrasekhar AG,Eichmeyer S,Goldsmith-Pinkham P,Ogbu-Nwobodo L,Olken BA,Torres C,Sankar A,Vautrey PL,Duflo E

更新日期：2020-12-21 00:00:00

abstract：BACKGROUND:Lateral epicondylitis is a common condition for which botulinum toxin has been reported to have a therapeutic role in uncontrolled studies. OBJECTIVE:To determine if an injection of botulinum toxin is more effective than placebo for reducing pain in adults with lateral epicondylitis. DESIGN:Randomized, dou...

journal_title：Annals of internal medicine

authors： Wong SM,Hui AC,Tong PY,Poon DW,Yu E,Wong LK

更新日期：2005-12-06 00:00:00

abstract：OBJECTIVE:To describe how the results of bone densitometry affect women's decisions about measures to prevent fractures and to determine whether labeling women as having below-normal bone density has adverse effects. DESIGN:Mail survey of a random sample of women. SETTING:Four community hospitals in the San Francisco...

journal_title：Annals of internal medicine

authors： Rubin SM,Cummings SR

更新日期：1992-06-15 00:00:00

abstract：:Seventy homosexual men with unexplained persistent diffuse lymphadenopathy enrolled in a prospective natural history study from November 1981 to November 1982. These men had demographic, clinical, and laboratory findings similar to those of homosexual patients with the acquired immunodeficiency syndrome. Pathologic ex...

journal_title：Annals of internal medicine

authors： Abrams DI,Lewis BJ,Beckstead JH,Casavant CA,Drew WL

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Motor vehicle crashes (MVCs) remain a leading cause of injury-related deaths in the United States. Primary seat belt laws allow vehicle occupants to be ticketed solely for not wearing seat belts, and secondary laws allow ticketing only for failure to wear seat belts in the setting of other violations. OBJEC...

journal_title：Annals of internal medicine

authors： Lee LK,Monuteaux MC,Burghardt LC,Fleegler EW,Nigrovic LE,Meehan WP,Schutzman SA,Mannix R

更新日期：2015-08-04 00:00:00

abstract：BACKGROUND:Apolipoprotein E (apoE) genotypes play critical roles in lipid metabolism and are believed to influence risk for coronary heart disease (CHD). Despite many population studies, however, the impact of apoE polymorphism on risk for CHD remains uncertain. PURPOSE:To qualitatively and quantitatively assess the e...

journal_title：Annals of internal medicine

authors： Song Y,Stampfer MJ,Liu S

更新日期：2004-07-20 00:00:00

abstract：:We describe a sporadic, vitamin-D-resistant osteomalacic syndrome in 19 patients undergoing hemodialysis. The syndrome was found in less than 1.5% of patients from referring dialysis centers. All 19 patients had multiple fractures, severe myopathy, and many developed spontaneous hypercalcemia. Severe osteomalacia with...

journal_title：Annals of internal medicine

authors： Hodsman AB,Sherrard DJ,Wong EG,Brickman AS,Lee DB,Alfrey AC,Singer FR,Norman AW,Coburn JW

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Memphis and Shelby County, Tennessee, experienced an epidemic of hepatitis A in 1994 and 1995. More than 1700 cases were reported. OBJECTIVE:To characterize the clinical features of patients hospitalized during a large urban epidemic of hepatitis A. DESIGN:Retrospective chart review. SETTING:15 acute care...

journal_title：Annals of internal medicine

authors： Willner IR,Uhl MD,Howard SC,Williams EQ,Riely CA,Waters B

更新日期：1998-01-15 00:00:00