Combined idiopathic neutropenia and thrombocytopenia: evidence for an immune basis for the syndrome.

Abstract:

:We report a case of combined idiopathic immune neutropenia and immune thrombocytopenia (thromboneutropenia). Therapy with prednisone was ineffective. Treatment with vincristine raised the patient's platelet count but did not increase the neutrophil count. Splenectomy led to a prompt complete remission. Using radioimmunologic techniques, we have shown both antiplatelet and antineutrophil antibodies and have shown the disappearance of these antibodies after successful treatment.

journal_name

Ann Intern Med

authors

Linker CA,Newcom SR,Nilsson CM,Wolf JL,Shuman MA

doi

10.7326/0003-4819-93-5-704

subject

Has Abstract

pub_date

1980-11-01 00:00:00

pages

704-7

issue

5

eissn

0003-4819

issn

1539-3704

journal_volume

93

pub_type

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