Cloning of an avian adeno-associated virus (AAAV) and generation of recombinant AAAV particles.

abstract：:An unusual set of 3' coterminal, spliced mRNAs transcribed through the BamHI A fragment have been previously identified in nasopharyngeal carcinoma (NPC) tissues. These RNAs have also been detected at low levels in Burkitt's lymphoma (BL) cell lines and Epstein-Barr virus (EBV)-transformed lymphocytes. Sequence analys...

journal_title：Journal of virology

authors： Fries KL,Sculley TB,Webster-Cyriaque J,Rajadurai P,Sadler RH,Raab-Traub N

更新日期：1997-04-01 00:00:00

abstract：:Borna disease virus infection is diagnosed by the presence of serum antibodies reactive with the major viral proteins, p40 and p23. Although p40 and p23 are unrelated in amino acid sequence structure, cross-reactive antibodies are described. Protein fragments and synthetic peptides were analyzed to characterize the sp...

journal_title：Journal of virology

authors： Kliche S,Stitz L,Mangalam H,Shi L,Binz T,Niemann H,Briese T,Lipkin WI

更新日期：1996-11-01 00:00:00

abstract：:Defective interfering RNAs have long been thought to be a causal factor of persistent RNA virus infections. Here we describe a novel type of defective genome of lymphocytic choriomeningitis virus and the unique mechanism by which these RNAs appear to contribute to the establishment and maintenance of persistent infect...

journal_title：Journal of virology

authors： Meyer BJ,Southern PJ

更新日期：1997-09-01 00:00:00

abstract：:Two major outer envelope glycoproteins of Epstein-Barr virus, gp350 and gp220, are known to be encoded by 3.2- and 2.5-kilobase RNAs which map to the same DNA fragment (M. Hummel, D. Thorley-Lawson, and E. Kieff, J. Virol. 49:413-417). These RNAs have the same 5' and 3' ends. The larger RNA is encoded by a 2,777-base ...

journal_title：Journal of virology

authors： Beisel C,Tanner J,Matsuo T,Thorley-Lawson D,Kezdy F,Kieff E

更新日期：1985-06-01 00:00:00

abstract：:The purpose of this study was to determine whether a cell surface protein that can serve as coreceptor for herpes simplex virus type 1 (HSV-1) entry, herpesvirus entry mediator (previously designated HVEM but renamed HveA), also mediates HSV-1-induced cell-cell fusion. We found that transfection of DNA from KOS-804, a...

journal_title：Journal of virology

authors： Terry-Allison T,Montgomery RI,Whitbeck JC,Xu R,Cohen GH,Eisenberg RJ,Spear PG

更新日期：1998-07-01 00:00:00

abstract：:The human immunodeficiency virus type 1 Tat protein binds to an RNA stem-loop structure called TAR which is present at the 5' end of all human immunodeficiency virus type 1 transcripts. This binding is centered on a bulge within the stem of TAR and is an essential step in the trans-activation process which results in ...

journal_title：Journal of virology

authors： Sumner-Smith M,Roy S,Barnett R,Reid LS,Kuperman R,Delling U,Sonenberg N

更新日期：1991-10-01 00:00:00

abstract：:Protein kinase activity in general is stimulated at least 5- to 10-fold in ribosomal salt wash preparations from poliovirus-infected HeLa cells compared with those from mock-infected cells. The stimulation of kinase activity is manifested by increased phosphorylation of ribosome-associated polypeptides having approxim...

journal_title：Journal of virology

authors： Ransone LJ,Dasgupta A

更新日期：1987-06-01 00:00:00

abstract：:Infection with human T-cell leukemia virus type 1 (HTLV-1) can result in the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic inflammatory disease of the central nervous system (CNS). HTLV-2 is highly related to HTLV-1 at the genetic level and shares a high degree of sequen...

journal_title：Journal of virology

authors： Banerjee P,Rochford R,Antel J,Canute G,Wrzesinski S,Sieburg M,Feuer G

更新日期：2007-02-01 00:00:00

abstract：:The novel low-pathogenic avian influenza A H7N9 viruses (LPAI H7N9 viruses) have been a threat to public health since their emergence in 2013 because of the high rates of mortality and morbidity that they cause. Recently, highly pathogenic variants of these avian influenza A H7N9 viruses (HPAI H7N9 viruses) have emerg...

journal_title：Journal of virology

authors： Yang L,Zhu W,Li X,Chen M,Wu J,Yu P,Qi S,Huang Y,Shi W,Dong J,Zhao X,Huang W,Li Z,Zeng X,Bo H,Chen T,Chen W,Liu J,Zhang Y,Liang Z,Shi W,Shu Y,Wang D

更新日期：2017-11-14 00:00:00

abstract：:Nucleotide sequence analysis of two simian virus 40 early mutants dl1263 and dl1265, which lack a DNA segment around map positions 0.21 and 0.18, respectively (C. Cole, T. Landers, S. Goff, S. MAnteuil-Brutlag, and P. Berg, J. Virol. 24:277--294, 1977), revealed in-phase deletions of 33 nucleotide pairs for dl1263 and...

journal_title：Journal of virology

authors： Van Heuverswyn H,Cole C,Berg P,Fiers W

更新日期：1979-06-01 00:00:00

abstract：:The matrix (MA) protein of human immunodeficiency virus type 1 (HIV-1) forms the outer protein shell directly underneath the lipid envelope of the virion. The MA protein has a key role in different aspects of virus assembly, including the incorporation of the HIV-1 Env protein complex, which contains a transmembrane g...

journal_title：Journal of virology

authors： Mammano F,Kondo E,Sodroski J,Bukovsky A,Göttlinger HG

更新日期：1995-06-01 00:00:00

abstract：UNLABELLED:We have recently shown in both herpesviruses and phages that packaged viral DNA creates a pressure of tens of atmospheres pushing against the interior capsid wall. For the first time, using differential scanning microcalorimetry, we directly measured the energy powering the release of pressurized DNA from th...

journal_title：Journal of virology

authors： Bauer DW,Li D,Huffman J,Homa FL,Wilson K,Leavitt JC,Casjens SR,Baines J,Evilevitch A

更新日期：2015-09-01 00:00:00

abstract：:Three drug-dependent mutants of human rhinovirus 16 (HRV16) were characterized by sequence analyses of spontaneous mutant isolates and were genetically reconstructed from a parental cDNA plasmid. These mutants formed plaques in the presence but not in the absence of the selecting antiviral drug, WIN 52035, which binds...

journal_title：Journal of virology

authors： Wang W,Lee WM,Mosser AG,Rueckert RR

更新日期：1998-02-01 00:00:00

abstract：:Ocular herpes simplex keratitis (HSK) is a consequence of viral reactivations from trigeminal ganglia (TG) and occurs almost exclusively in the same eye in humans. In our murine oro-ocular (OO) model, herpes simplex virus 1 (HSV-1) inoculation in one side of the lip propagates virus to infect the ipsilateral TG. Repli...

journal_title：Journal of virology

authors： Poccardi N,Rousseau A,Haigh O,Takissian J,Naas T,Deback C,Trouillaud L,Issa M,Roubille S,Juillard F,Efstathiou S,Lomonte P,Labetoulle M

更新日期：2019-11-26 00:00:00

abstract：:Closed circular unintegrated DNA of the SEATO strain of gibbon ape leukemia virus (GaLV-S) was isolated from canine thymus fibroblasts after cocultivation with chronically infected bat lung fibroblasts. Restriction endonuclease HindIII cleaves GaLV-S DNA once, thus allowing isolation and cloning of HindIII-digested un...

journal_title：Journal of virology

authors： Gelmann EP,Trainor CD,Wong-Staal F,Reitz MS

更新日期：1982-10-01 00:00:00

abstract：:The specificity of herpes simplex virus type 1-specific cytotoxic T cells was examined with target cells expressing either input viral structural antigens or antigens resulting from permissive infection or cells from an interrupted infection in which they expressed predominantly nonstructural immediate-early proteins....

journal_title：Journal of virology

authors： Martin S,Courtney RJ,Fowler G,Rouse BT

更新日期：1988-07-01 00:00:00

abstract：:To identify retroviral antigenic determinants recognized by CD4+ T helper cells during tumor rejection, we established four noncytolytic, helper-type, CD4+ T-cell clones by limiting dilution cultures of mixed lymphocyte-tumor cultures from mice immune to a Friend virus-induced tumor, FBL-3. Among these, three T helper...

journal_title：Journal of virology

authors： Iwashiro M,Kondo T,Shimizu T,Yamagishi H,Takahashi K,Matsubayashi Y,Masuda T,Otaka A,Fujii N,Ishimoto A

更新日期：1993-08-01 00:00:00

abstract：:We measured the quantity of plasma feline immunodeficiency virus (FIV) RNA using a real-time sequence detecting system. Plasma viral RNA load was shown to correlate with the clinical stage, survival time, and disease progression in naturally FIV-infected cats. The present study indicates that the plasma viral RNA load...

journal_title：Journal of virology

authors： Goto Y,Nishimura Y,Baba K,Mizuno T,Endo Y,Masuda K,Ohno K,Tsujimoto H

更新日期：2002-10-01 00:00:00

abstract：:The herpes simplex virus type 1 (HSV-1) immediate-early protein ICP27 is an essential regulatory protein that localizes to the nuclei of infected cells. The strong nuclear localization signal (NLS) of ICP27 was identified recently and shown to reside in the amino-terminal portion of the polypeptide from residues 110 t...

journal_title：Journal of virology

authors： Hibbard MK,Sandri-Goldin RM

更新日期：1995-08-01 00:00:00

abstract：:It has previously been shown that an electrophoretic variant form of the Rous sarcoma virus transforming protein, pp60v-src, exists in src-transformed cells. This variant, which was readily observed in vanadate-treated cells, was characterized as possessing extensive amino-terminal domain phosphotyrosine modification....

journal_title：Journal of virology

authors： Collett MS,Belzer SK

更新日期：1987-05-01 00:00:00

abstract：:Rinderpest virus is a morbillivirus and is the causative agent of a widespread and important disease of cattle. The viral genome is a single strand of RNA in the negative sense. We have constructed plasmids containing cDNA copies of the 5' and 3' termini of the virus separated by a reporter gene and have shown that an...

journal_title：Journal of virology

authors： Baron MD,Barrett T

更新日期：1997-02-01 00:00:00

abstract：:We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses bear the C-terminal ligand sequence Glu-Ser-Glu-Val (ESEV) for PDZ domains present in multiple ...

journal_title：Journal of virology

authors： Zielecki F,Semmler I,Kalthoff D,Voss D,Mauel S,Gruber AD,Beer M,Wolff T

更新日期：2010-10-01 00:00:00

abstract：UNLABELLED:Demonstrating direct interactions between host and virus proteins during infection is a major goal and challenge for the field of virology. Most protein interactions are not binary or easily amenable to structural determination. Using infectious preparations of a polerovirus (Potato leafroll virus [PLRV]) an...

journal_title：Journal of virology

authors： DeBlasio SL,Chavez JD,Alexander MM,Ramsey J,Eng JK,Mahoney J,Gray SM,Bruce JE,Cilia M

更新日期：2015-12-09 00:00:00

abstract：:The genome of the simian virus 40 (SV40) temperature-sensitive (ts) mutant tsD202 rescued by passage on transformed permissive monkey lines (see accompanying paper [Y. Gluzman et al., J. Virol. 24:534-540, 1977]) was analyzed by restriction endonuclease cleavage mapping to obtain biochemical evidence that the rescue o...

journal_title：Journal of virology

authors： Vogel T,Gluzman Y,Winocour E

更新日期：1977-11-01 00:00:00

abstract：:Sequences present at the genomic termini of herpesviruses become linked during lytic-phase replication and provide the substrate for cleavage and packaging of unit length viral genomes. We have previously shown that homologs of the consensus herpesvirus cleavage-packaging signals, pac1 and pac2, are located at the lef...

journal_title：Journal of virology

authors： Deng H,Dewhurst S

更新日期：1998-01-01 00:00:00

abstract：:Infection of receptor-bearing cells by coronaviruses is mediated by their spike (S) proteins. The coronavirus (SARS-CoV) that causes severe acute respiratory syndrome (SARS) infects cells expressing the receptor angiotensin-converting enzyme 2 (ACE2). Here we show that codon optimization of the SARS-CoV S-protein gene...

journal_title：Journal of virology

authors： Moore MJ,Dorfman T,Li W,Wong SK,Li Y,Kuhn JH,Coderre J,Vasilieva N,Han Z,Greenough TC,Farzan M,Choe H

更新日期：2004-10-01 00:00:00

abstract：:Herpesvirus saimiri (HVS) is the prototype gamma-2 herpesvirus, which naturally infects the squirrel monkey Saimiri sciureus, causing an asymptomatic but persistent infection. The latent phase of gamma-2 herpesviruses is characterized by their ability to persist in a dividing cell population while expressing a limited...

journal_title：Journal of virology

authors： Griffiths R,Whitehouse A

更新日期：2007-04-01 00:00:00

abstract：UNLABELLED:The accessory gene vpr, common to all primate lentiviruses, induces potent G2/M arrest in cycling cells. A recent study showed that human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) mediates this through activation of the SLX4/MUS81/EME1 exonuclease complex that forms part of the Fanconi anem...

journal_title：Journal of virology

authors： Berger G,Lawrence M,Hué S,Neil SJ

更新日期：2015-01-01 00:00:00

abstract：:Induction of virus-specific T-cell responses in mucosal as well as systemic compartments of the immune system is likely to be a critical feature of an effective AIDS vaccine. We investigated whether virus-specific CD8(+) lymphocytes induced in rhesus macaques by immunization with attenuated simian immunodeficiency vir...

journal_title：Journal of virology

authors： Cromwell MA,Veazey RS,Altman JD,Mansfield KG,Glickman R,Allen TM,Watkins DI,Lackner AA,Johnson RP

更新日期：2000-09-01 00:00:00

abstract：:Chronic infection by hepatitis C virus (HCV) can lead to severe hepatitis and cirrhosis and is closely associated with hepatocellular carcinoma. The replication cycle of HCV is poorly understood but is likely to involve interaction with host factors. In this report, we show that NS5B, the HCV RNA-dependent RNA polymer...

journal_title：Journal of virology

authors： Goh PY,Tan YJ,Lim SP,Tan YH,Lim SG,Fuller-Pace F,Hong W

更新日期：2004-05-01 00:00:00