Abstract:
:The harmonic phase (HARP) method provides automatic and rapid analysis of tagged magnetic resonance (MR) images for quantification and visualization of myocardial strain. In this article, the development and implementation of a pulse sequence that acquires HARP images in real time are described. In this pulse sequence, a CINE sequence of images with 1-1 spatial modulation of magnetization (SPAMM) tags are acquired during each cardiac cycle, alternating between vertical and horizontal tags in successive heartbeats. An incrementing train of imaging RF flip angles is used to compensate for the decay of the harmonic peaks due to both T(1) relaxation and the applied imaging pulses. The magnitude images displaying coarse anatomy are automatically reconstructed and displayed in real time after each heartbeat. HARP strain images are generated offline at a rate of four images per second; real-time processing should be possible with faster algorithms or computers. A comparison of myocardial contractility in non-breath-hold and breath-hold experiments in normal humans is presented.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Sampath S,Derbyshire JA,Atalar E,Osman NF,Prince JLdoi
10.1002/mrm.10509subject
Has Abstractpub_date
2003-07-01 00:00:00pages
154-63issue
1eissn
0740-3194issn
1522-2594journal_volume
50pub_type
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