Allergic disorders in systemic lupus erythematosus.

abstract：:Lupus nephritis is an important cause of morbidity and mortality in patients with systemic lupus erythematosus. Traditional outcome criteria such as doubling of serum creatinine, end-stage renal disease and death have been used in controlled therapeutic trials, but are limited by their low incidence and the extended p...

journal_title：Lupus

authors： Boumpas DT,Balow JE

更新日期：1998-01-01 00:00:00

abstract：:We describe seven patients who developed malignancy before, after or at the onset of systemic lupus erythematosus (SLE). They comprise three cases of breast adenocarcinoma, two cases of Hodgkin's lymphoma, and one each of cholangiocarcinoma and thymoma. Only one of this group had been treated with cytotoxic agents, an...

journal_title：Lupus

authors： Menon S,Snaith ML,Isenberg DA

更新日期：1993-06-01 00:00:00

abstract：:Women's treatment preferences for lupus nephritis vary widely even after adjusting for sociodemographic factors and disease severity. Attitude toward risk may partially explain interpatient variability in treatment preference. The objective of this study was to examine the association between 'risk-attitude' and patie...

journal_title：Lupus

authors： Fraenkel L,Bogardus ST Jr,Wittink DR

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To determine whether the intrathecal concentrations of cytokines/chemokines are associated with, or influenced by, serum concentrations in patients with central neuropsychiatric systemic lupus erythematosus (NPSLE), and to ascertain whether the increased production of cytokines/chemokines intrathecally relati...

journal_title：Lupus

authors： Yoshio T,Okamoto H,Kurasawa K,Dei Y,Hirohata S,Minota S

更新日期：2016-08-01 00:00:00

abstract：:The objective of this study was to assess the incidence and risk factors of infections in 200 SLE outpatients. All outpatients with active or inactive SLE without infections in the previous month were included. They were assessed every 3 months. Major infections were those requiring hospitalization and parental antibi...

journal_title：Lupus

authors： Zonana-Nacach A,Camargo-Coronel A,Yañez P,Sánchez L,Jimenez-Balderas FJ,Fraga A

更新日期：2001-01-01 00:00:00

abstract：:Structural and metabolic abnormalities in the hippocampus have been associated with the pathophysiological mechanism of central nervous system involvement in primary Sjögren syndrome (pSS). Nevertheless, how hippocampal function is altered in pSS remains unknown. The purpose of our study is to investigate the alterati...

journal_title：Lupus

authors： Zhang XD,Zhao LR,Zhou JM,Su YY,Ke J,Cheng Y,Li JL,Shen W

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Identifying factors predicting adverse pregnancy outcomes involving systemic lupus erythematosus (SLE) is a research priority. The aims of this study were to investigate (a) the maternal and fetal outcomes of pregnant lupus patients and the factors associated with adverse pregnancy outcomes, and (b) the ef...

journal_title：Lupus

authors： Janardana R,Haridas V,Priya V,Bhat V,Singh Y,Rao VK,Jois R,Srikantiah C,Pinto B,Shobha V

更新日期：2020-10-01 00:00:00

abstract：:Neurological involvement in antiphospholipid antibody syndrome (APS) is common, and its occurrence increases morbidity and mortality. Patients may present variable neurological involvement, such as cerebrovascular disease, cognitive dysfunction, headache, seizures, movement disorders, multiple sclerosis-like syndrome,...

journal_title：Lupus

authors： Ricarte IF,Dutra LA,Abrantes FF,Toso FF,Barsottini OGP,Silva GS,de Souza AWS,Andrade D

更新日期：2018-08-01 00:00:00

abstract：:Pulmonary hypertension (PH) can occur at any time during the course of systemic lupus erythematosus (SLE), and can be independent of lupus disease activity in other systems. The pathogenesis of PH in SLE can be multifactorial, but pulmonary arterial hypertension (PAH) is the commonest cause of PH in SLE. The internati...

journal_title：Lupus

authors： Prabu A,Gordon C

更新日期：2013-10-01 00:00:00

abstract：:We report the case of a fetus with proliferative glomerulonephritis in the context of maternal systemic lupus erythematosus (SLE). The pattern of the renal lesions correspond to the class III of revisited WHO classification of glomerulonephritis in SLE. Amniotic fluid analysis showed a high level of albumin and the pr...

journal_title：Lupus

authors： Daïkha-Dahmane F,Bault JP,Molina-Gomes D,Hillion D,Ville Y

更新日期：2005-01-01 00:00:00

abstract：:In order to ascertain the incidence of monoclonal gammopathy (MG) in systemic lupus erythematosus (SLE), 120 SLE patients were evaluated. Four patients (3.3%), two of whom were under 50 years of age, were found to have a monoclonal immunoglobulin in their serum. Our data agree with the previous literature in demonstra...

journal_title：Lupus

authors： Porcel JM,Ordi J,Tolosa C,Selva A,Castro-Salomo A,Vilardell M

更新日期：1992-08-01 00:00:00

abstract：:Spondyloenchondrodysplasia (SPENCD) is a rare autosomal recessive skeletal dysplasia caused by recessive mutations in the ACP5 gene, and it is characterized by the persistence of chondroid tissue islands within the bone. The clinical spectrum of SPENCD includes neurological involvement and immune dysfunction, such as ...

journal_title：Lupus

authors： Bilginer Y,Düzova A,Topaloğlu R,Batu ED,Boduroğlu K,Güçer Ş,Bodur I,Alanay Y

更新日期：2016-06-01 00:00:00

abstract：:Vaccines have undoubtedly brought overwhelming benefits to mankind and are considered safe and effective. Nevertheless, they can occasionally stimulate autoantibody production or even a recently defined syndrome known as autoimmune/inflammatory syndrome induced by adjuvants (ASIA). There is scarce data regarding autoi...

journal_title：Lupus

authors： Perdan-Pirkmajer K,Thallinger GG,Snoj N,Čučnik S,Žigon P,Kveder T,Logar D,Praprotnik S,Tomšič M,Sodin-Semrl S,Ambrožič A

更新日期：2012-02-01 00:00:00

abstract：:Data on the clinical and laboratory profiles of 83 children with SLE have been analysed and compared with data on 187 adults with the disease. The clinical features of childhood SLE are similar to those seen in adults, although clinical and laboratory parameters reflect propensity to a more severe form of the disease ...

journal_title：Lupus

authors： Pande I,Sekharan NG,Kailash S,Uppal SS,Singh RR,Kumar A,Malaviya AN

更新日期：1993-04-01 00:00:00

abstract：:The objective of the study was to analyse the prevalence and clinical significance of hypocomplementemia in a large series of patients diagnosed either with systemic lupus erythematosus (SLE) or with primary antiphospholipid syndrome (APS) and its association with the main clinical, hematological and immunological fea...

journal_title：Lupus

authors： Ramos-Casals M,Campoamor MT,Chamorro A,Salvador G,Segura S,Botero JC,Yagüe J,Cervera R,Ingelmo M,Font J

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:We analyzed data of lupus nephritis (LN) patients to find parameters that can predict remission. METHODS:Sixty-four LN patients who were diagnosed with class III, IV, V or V + III/IV by renal biopsy and were followed up for more than six months in our center were enrolled retrospectively. Receiver operating ...

journal_title：Lupus

authors： Liu G,Wang H,Le J,Lan L,Xu Y,Yang Y,Chen J,Han F

更新日期：2019-03-01 00:00:00

abstract：:Fatigue is one of the most complex and ill understood symptoms of chronic illness often reported as the number one complaint by patients with systemic lupus erythematosus (SLE). This paper aims to provide a comprehensive review of the literature on fatigue in SLE. A pool of 55 relevant articles was retrieved via elect...

journal_title：Lupus

authors： Cleanthous S,Tyagi M,Isenberg DA,Newman SP

更新日期：2012-04-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a connective tissue disease where inflammatory activity affects several organ systems. An increased risk of cardiovascular disease has been identified in these patients, even after correction for traditional risk factors. The aim of the present study was to evaluate arterial stiff...

journal_title：Lupus

authors： Bjarnegråd N,Bengtsson C,Brodszki J,Sturfelt G,Nived O,Länne T

更新日期：2006-01-01 00:00:00

abstract：:Renal involvement is one of the main complications of systemic lupus erythematosus, causing a significant impact on patients' morbidity and mortality. Renal biopsy is still the gold standard of diagnosis, but it has many limitations. In this sense, several recent studies aim to identify biomarkers that not only predic...

journal_title：Lupus

authors： Gasparin AA,Pamplona Bueno de Andrade N,Hax V,Tres GL,Veronese FV,Monticielo OA

更新日期：2019-03-01 00:00:00

abstract：:Cytomegalovirus (CMV) is particularly dangerous in systemic lupus erythematosus (SLE), being a problem both for the differential diagnosis with disease flare and for the management of SLE flare with immunosuppressive drugs. We report on four cases of SLE with concomitant CMV infection, having some common clinical and ...

journal_title：Lupus

authors： Sebastiani GD,Iuliano A,Canofari C,Bracci M

更新日期：2019-03-01 00:00:00

abstract：:In a 76-week, randomized controlled trial, patients received 100 mg LJP 394 or placebo weekly for 16 weeks followed by three 12-week treatment cycles of 50 mg LJP 394 or placebo weekly each separated by eight-week periods when no therapy was administered. Health-related quality of life (HRQOL) was assessed using SF-36...

journal_title：Lupus

authors： Strand V,Aranow C,Cardiel MH,Alarcón-Segovia D,Furie R,Sherrer Y,Tumlin J,Wallace DJ,Crawford B,LJP 394 Investigator Consortium.

更新日期：2003-01-01 00:00:00

abstract：:This study assessed the expression of complement receptor 1 (CR1), decay accelerating factor (DAF) and membrane inhibitor of reactive lysis (CD59) on the erythrocytes and glomerulus of diffuse proliferative glomerulonephritis (DPGN) of systemic lupus erythematosus (SLE) patients using flow cytometry and immunofluoresc...

journal_title：Lupus

authors： Arora M,Arora R,Tiwari SC,Das N,Srivastava LM

更新日期：2000-01-01 00:00:00

abstract：:In the 9-year period between 1982 and 1991, 137 patients attending a medical clinic of Queen Elizabeth Hospital, Hong Kong, were diagnosed as having systemic lupus erythematosus according to the American Rheumatism Association's criteria for classification. The female-to-male ratio was 16 to 1. Commonly the onset age ...

journal_title：Lupus

authors： Lee SS,Li CS,Li PC

更新日期：1993-04-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is characterized by multiple autoantibodies and complement activation. Recent studies have suggested that anti-nuclear antibody (ANA) positivity may disappear over time in some SLE patients. Anti-double-stranded DNA (dsDNA) antibody titers and complement levels may vary with time and...

journal_title：Lupus

authors： Ippolito A,Wallace DJ,Gladman D,Fortin PR,Urowitz M,Werth V,Costner M,Gordon C,Alarcón GS,Ramsey-Goldman R,Maddison P,Clarke A,Bernatsky S,Manzi S,Bae SC,Merrill JT,Ginzler E,Hanly JG,Nived O,Sturfelt G,Sanchez-Gu

更新日期：2011-03-01 00:00:00

abstract：:Patients with chronic hepatitis C virus (HCV) infection frequently present with extrahepatic manifestations covering a large spectrum, involving different organ systems leading to the concept of systemic HCV infection. These manifestations include autoimmune phenomena and frank autoimmune and/or rheumatic diseases and...

journal_title：Lupus

authors： Rosenthal E,Cacoub P

更新日期：2015-04-01 00:00:00

abstract：:We describe a patient with rheumatoid arthritis (RA) whose sera contained a high titre of an antibody targeting cytoplasmic ribosomal P proteins (anti-P). This association preceded by 6 years the development of serological and clinical manifestations of systemic lupus erythematosus (SLE). The clinical significance of ...

journal_title：Lupus

authors： Hamasaki K,Mimura T,Kanda H,Morino N,Yazaki Y,Nojima Y

更新日期：1997-01-01 00:00:00

abstract：:We report an infant with anticardiolipin (aCL) antibodies who presented with erythematous nodular skin lesions and elevated liver enzyme levels. The cutaneous manifestation was histologically lymphocytic lobular panniculitis with vasculitic and hemorrhagic changes. The infant also had low levels of anti-double strande...

journal_title：Lupus

authors： Miyagawa S,Uchida Y,Taira K,Higuchi M,Hashimoto K,Yoshioka A,Shirai T

更新日期：2000-01-01 00:00:00

abstract：:A special interaction is established during pregnancy between the maternal immune system and fetal cells to allow the survival and the normal growth of the fetus. Fetal cells expressing paternal alloantigens are not recognized as foreign by the mother because of an efficient anatomic barrier and a local immunosuppress...

journal_title：Lupus

authors： Bulla R,Fischetti F,Bossi F,Tedesco F

更新日期：2004-01-01 00:00:00

abstract：:Objective The objective of this report is to evaluate the prevalence and clinico-serological correlations of anti-α-enolase antibody (Ab) in patients with systemic lupus erythematosus (SLE). Methods Thirty-two untreated patients with SLE and 20 age- and sex-matched healthy controls were evaluated by rheumatologic exam...

journal_title：Lupus

authors： Li M,Li J,Wang J,Li Y,Yang P

更新日期：2018-01-01 00:00:00

abstract：:Abnormalities of the lipid profile partly explain the atherogenic tendency of systemic lupus erythematosus but the picture is unclear in thrombotic primary antiphospholipid syndrome (PAPS). Herein we compare the lipid profile, high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol (CHO), apol...

journal_title：Lupus

authors： Ames PR,Matsuura E,Batuca JR,Ciampa A,Lopez LL,Ferrara F,Iannaccone L,Alves JD

更新日期：2010-05-01 00:00:00