Abstract：
:Thioridazine and visual screening procedures are effective in reducing the stereotypic behaviors of individuals with mental retardation. A double-blind, placebo-controlled study, using alternating treatments within a multiple-baseline across subjects design, was conducted to assess the effects of two doses of thioridazine (1.25 and 2.5 mg/kg/day) and visual screening, alone and combined, on stereotypy and social behavior of three individuals with profound mental retardation. Functional analyses did not show demand, alone, social attention, or differential reinforcement conditions to maintain the subjects' stereotypy. Thioridazine was effective in producing modest reductions in stereotypy and minor increases in social behavior across subjects. The higher dose of thioridazine (2.5 mg/kg/day) was slightly more effective than the lower dose (1.25 mg/kg/day), and thioridazine plus visual screening was more effective than thioridazine alone. The most effective treatment was visual screening when used in the absence of thioridazine. This study demonstrates a method for assessing the impact of psychopharmacological and behavioral interventions in individuals for whom a behavioral treatment cannot be easily derived from a functional analysis of the maintaining conditions of the target behavior.
journal_name
Res Dev Disabiljournal_title
Research in developmental disabilitiesauthors
Singh NN,Landrum TJ,Ellis CR,Donatelli LSdoi
10.1016/0891-4222(93)90028-isubject
Has Abstractpub_date
1993-05-01 00:00:00pages
163-77issue
3eissn
0891-4222issn
1873-3379pii
0891-4222(93)90028-Ijournal_volume
14pub_type
临床试验,杂志文章abstract：:Individuals with the neurodevelopmental disorder Williams syndrome (WS) often report difficulty processing and acting in depth, such as crossing roads or reaching for objects; however little research attention has been directed at understanding depth perception and action in depth in WS and whether deficits in depth p...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2014.04.013
更新日期：2014-08-01 00:00:00
abstract：:The Social Skills Improvement System-Rating Scales (SSIS-RS; Gresham & Elliott, 2008) are designed to assist in the screening and classification of students (aged 5-18 years) who are suspected of presenting with social skills deficits and to offer guidelines in the development of interventions to remediate those types...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2016.11.019
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Children with Intellectual and Developmental Disabilities (IDD) face considerable challenges in participating in dental services. These challenges include resource constraints and inadequate skills of health service providers to work with this population. AIM:The aim was to scope published studies that addr...
journal_title：Research in developmental disabilities
pub_type： 杂志文章,评审
doi：10.1016/j.ridd.2017.12.022
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:Early speech-language development of individuals with Rett syndrome (RTT) has been repeatedly characterised by a co-occurrence of apparently typical and atypical vocalisations. AIMS:To describe specific features of this intermittent character of typical versus atypical early RTT-associated vocalisations by ...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2018.02.019
更新日期：2018-11-01 00:00:00
abstract：:Contrary to the expectations articulated in public policy, restrictive interventions are commonly used in support services for people with developmental disabilities. This systematic review and quantitative synthesis was undertaken to investigate whether the use of seclusion and restraints on people with developmental...
journal_title：Research in developmental disabilities
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.ridd.2013.08.010
更新日期：2013-11-01 00:00:00
abstract：:A Dutch version of the 'Measure of Processes of Care for Service Providers' (MPOC-SP) was developed to determine the extent to which professionals apply the principles of family-centred care in the rehabilitation of children with physical disabilities. However, no data were available on the reliability and construct v...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2014.03.044
更新日期：2014-07-01 00:00:00
abstract：:A morphing procedure has been designed to compare directly the perception of emotional expressions and of moving objects. Morphing tasks were presented to 12 low-functioning teenagers with Autism Spectrum Disorder (LF ASD) compared to 12 developmental age-matched typical children and a group presenting ceiling perform...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2015.09.025
更新日期：2015-12-01 00:00:00
abstract：AIM:This descriptive cross-sectional study estimates the frequencies and kinds of potential developmental disabilities (DD) and behavior problems (BP) among children in grades R and 1 who attend a primary public school in rural Western Cape Province, South Africa. METHODS:Data were collected on 174 children aged 5.1-8...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2009.05.006
更新日期：2009-11-01 00:00:00
abstract：:Previous studies have reported an inverse relationship between adaptive behavior and challenging behaviors in individuals with ID. However, it is unclear which characteristics might influence this relationship in individuals with ID and co-occurring conditions. We found a positive correlation between adaptive behavior...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2020.103718
更新日期：2020-09-01 00:00:00
abstract：:It is a widely accepted belief in clinical practice that children with a visual impairment can profit from the use of a low vision aid (LVA). However, we found a considerable gap in our scientific understanding of LVA use, particularly in young children. This is the reason for the analysis presented in this paper. A s...
journal_title：Research in developmental disabilities
pub_type： 杂志文章,评审
doi：10.1016/j.ridd.2011.01.027
更新日期：2011-05-01 00:00:00
abstract：:The aims of the preset study were to describe the profile of serum uric acid, the prevalence of hyperuricemia and its risk factors among children and adolescents with intellectual disabilities. We conducted a cross-sectional study of 941 children and adolescents with intellectual disabilities (aged 4-18 years) who par...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2009.07.008
更新日期：2009-11-01 00:00:00
abstract：:This study aimed to explore the generalization of contextual integration from within-modality (visual-visual) to cross-modal (visual-auditory) processing in people with Williams syndrome (WS), and to clarify whether the concreteness or social relatedness of stimuli contributed to contextual coherence using pictures. C...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.09.002
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:People with intellectual and developmental disabilities (IDD) are at risk of developing long term health conditions, and a preventative health agenda research is emerging. However, little is known about the recruitment settings, delivery contexts, intervention techniques and outcomes of health promotion prog...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2020.103592
更新日期：2020-02-05 00:00:00
abstract：:This study compares the family financial and employment impacts of having a child with fragile X syndrome (FXS), autism spectrum disorder (ASD), or intellectual disabilities (ID). Data from a 2011 national survey of families of children with FXS were matched with data from the National Survey of Children with Special ...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2014.04.009
更新日期：2014-07-01 00:00:00
abstract：:Locomotion of children and adults with a visual impairment (ages 1-44, n = 28) was compared to that of age-related individuals with normal vision (n = 60). Participants walked barefoot at preferred speed while their gait was recorded by a Vicon(®) system. Walking speed, heading angle, step frequency, stride length, st...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.08.017
更新日期：2011-11-01 00:00:00
abstract：:Deficits in auditory short-term memory have been widely reported in children with Specific Language Impairment (SLI), and recent evidence suggests that children with Autism Spectrum Disorder and co-morbid language impairment (ALI) experience similar difficulties. Music, like language relies on auditory memory and the ...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2018.06.001
更新日期：2018-09-01 00:00:00
abstract：:Few studies have investigated in detail which factors influence activities of daily living (ADL) in adults with intellectual disabilities (ID) comorbid with/without dementia conditions. The objective of the present study was to describe the relation between early onset dementia conditions and progressive loss of ADL c...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.12.015
更新日期：2014-03-01 00:00:00
abstract：:Childhood attention-deficit hyperactivity disorder (ADHD) is associated with academic underachievement and school dysfunction. Little is known whether such association varies with the persistence of ADHD symptoms. The authors investigated school functioning among youths with and without persistent ADHD and identified ...
journal_title：Research in developmental disabilities
pub_type： 临床试验,杂志文章
doi：10.1016/j.ridd.2012.09.004
更新日期：2013-01-01 00:00:00
abstract：:Individuals with autism spectrum disorders (ASDs) can demonstrate hypersensitivity to sounds as well as a lack of awareness of them. Several functional imaging studies have suggested an abnormal response in the auditory cortex of such subjects, but it is not known whether these subjects have dysfunction in the auditor...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.10.016
更新日期：2012-03-01 00:00:00
abstract：:Predictors of depression over time were examined in parental carers of children with developmental disabilities (DD) and parents of typically developing children (controls) who participated in the Growing up in Ireland Study. Parents completed measures of depression, the Centre for Epidemiological Depression Scale (CE...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2018.07.001
更新日期：2018-09-01 00:00:00
abstract：INTRODUCTION:Unilateral visuospatial deficits have been observed in children with brain damage. While the effectiveness of prism adaptation for treating unilateral neglect in adult stroke patients has been demonstrated previously, the usefulness of prism adaptation in a pediatric population is still unknown. The presen...
journal_title：Research in developmental disabilities
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ridd.2015.06.009
更新日期：2015-08-01 00:00:00
abstract：PURPOSE:Current research suggests that supported employment for people with developmental disabilities offers significantly higher rates of employment, personal satisfaction, and employer satisfaction. This study focuses on tensions experienced by employment support professionals while working with employers regarding ...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2020.103603
更新日期：2020-02-08 00:00:00
abstract：:Children with hemiparetic Cerebral Palsy (CP) walk with marked asymmetries. For instance, we have recently shown that they have less arm swing on the affected side, and more arm swing at the unaffected side. Such an increase in arm swing at the unaffected side may be aimed at controlling total body angular momentum ab...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.05.019
更新日期：2011-11-01 00:00:00
abstract：:This study assessed whether three patients with Alzheimer's disease could learn to use urine alarms and caregivers' prompts to eliminate large urinary accidents. As soon as the patient began to release urine, the alarm system presented auditory and vibratory signals. In relation to those signals, the caregiver would p...
journal_title：Research in developmental disabilities
pub_type： 临床试验,杂志文章
doi：10.1016/j.ridd.2011.04.011
更新日期：2011-09-01 00:00:00
abstract：:This study explored self concepts in matched groups of adolescents and adults with Williams syndrome (WS) and Prader-Willi syndrome (PWS), using Damon and Hart's semi-structured interview. The main findings were that the WS participants were more productive in their responses to the interview, providing more self char...
journal_title：Research in developmental disabilities
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.ridd.2003.05.003
更新日期：2004-03-01 00:00:00
abstract：:The present study sought to examine the longitudinal psychoeducational, neurocognitive, and psychiatric outcomes of children and adolescents with chromosome 22q11.2 deletion syndrome (22q11DS), a population with a high incidence of major psychiatric illnesses appearing in late adolescence/early adulthood. Little is kn...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2012.12.003
更新日期：2013-05-01 00:00:00
abstract：:The present study examined whether atypical visual processing is related to the level of social skills in children with autism spectrum disorder (ASD). Thirty-eight young children with ASD (29 boys, 9 girls) were included. Atypical visual processing was assessed by coding the number of lateral glances and the amount o...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.11.012
更新日期：2014-02-01 00:00:00
abstract：:From an applied behavior-analytic perspective, aggression in people with intellectual disabilities is mostly maintained by social reinforcement consequences. However, nonsocial consequences have also been identified in functional assessments on aggression. Behaviors producing their own reinforcement have been labeled ...
journal_title：Research in developmental disabilities
pub_type： 杂志文章,评审
doi：10.1016/j.ridd.2011.05.029
更新日期：2011-11-01 00:00:00
abstract：INTRODUCTION:The effects of prenatal exposure to alcohol are wide-ranging and pervasive in nature. In response to growing concerns about the lifelong disabilities related to prenatal alcohol exposure, a fetal alcohol spectrum disorder (FASD) diagnostic clinic was established in 2012. This was the first multi-disciplina...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2016.06.007
更新日期：2017-04-01 00:00:00
abstract：:Children with autism spectrum disorders (ASDs) are more likely to engage in inappropriate play (e.g., stereotypy, repetitive behavior) with their preferred items given as reinforcers. Considering the stereotyped behavior is a core characteristic of ASD aimed to reduce, it is necessary to identify alternative reinforce...
journal_title：Research in developmental disabilities
pub_type： 临床试验,杂志文章
doi：10.1016/j.ridd.2012.10.007
更新日期：2013-02-01 00:00:00
