Abstract：
:Individuals with autism spectrum disorders (ASDs) can demonstrate hypersensitivity to sounds as well as a lack of awareness of them. Several functional imaging studies have suggested an abnormal response in the auditory cortex of such subjects, but it is not known whether these subjects have dysfunction in the auditory cortex or are simply not listening. We measured changes in blood oxygenated hemoglobin (OxyHb) in the prefrontal and temporal cortices using near-infrared spectroscopy during various listening and ignoring tasks in 11 ASD and 12 control subjects. Here we show that the auditory cortex in ASD subjects responds to sounds fully during attention. OxyHb in the auditory cortex increased with intentional listening but not with ignoring of the same auditory stimulus in a similar fashion in both groups. Cortical responses differed not in the auditory but in the prefrontal region between the ASD and control groups. Thus, unawareness to sounds in ASD could be interpreted as due to inattention rather than dysfunction of the auditory cortex. Difficulties in attention control may account for the contrary behaviors of hypersensitivity and unawareness to sound in ASD.
journal_name
Res Dev Disabiljournal_title
Research in developmental disabilitiesauthors
Funabiki Y,Murai T,Toichi Mdoi
10.1016/j.ridd.2011.10.016subject
Has Abstractpub_date
2012-03-01 00:00:00pages
518-24issue
2eissn
0891-4222issn
1873-3379pii
S0891-4222(11)00395-7journal_volume
33pub_type
杂志文章abstract：:Children with autism spectrum disorder (ASD) often develop the word reading skills necessary to read text but struggle with reading comprehension. Comprehension skills are often under addressed in early elementary settings leaving children with ASD at a disadvantage once they are expected to read for meaning. This stu...
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journal_title：Research in developmental disabilities
pub_type： 杂志文章,评审
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pub_type： 临床试验,杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/s0891-4222(03)00060-x
更新日期：2003-09-01 00:00:00
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journal_title：Research in developmental disabilities
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journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.07.006
更新日期：2011-11-01 00:00:00
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journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.11.016
更新日期：2012-05-01 00:00:00
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journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.06.018
更新日期：2013-10-01 00:00:00
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journal_title：Research in developmental disabilities
pub_type： 临床试验,杂志文章
doi：10.1016/j.ridd.2013.07.010
更新日期：2013-10-01 00:00:00
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journal_title：Research in developmental disabilities
pub_type： 共识发展会议,杂志文章
doi：10.1016/j.ridd.2015.07.013
更新日期：2015-10-01 00:00:00
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pub_type： 杂志文章
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journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2012.03.031
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journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2017.08.001
更新日期：2017-11-01 00:00:00
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更新日期：2014-06-01 00:00:00
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journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2011.01.037
更新日期：2011-05-01 00:00:00
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journal_title：Research in developmental disabilities
pub_type： 杂志文章
doi：10.1016/j.ridd.2013.11.012
更新日期：2014-02-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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更新日期：1990-01-01 00:00:00
abstract：:Developmental coordination disorder (DCD) as well as overweight and obesity are of increasing importance in the study of human development. Data on the relation between DCD and obesity in adolescence are of particular interest because both phenomena are unlikely to disappear with age. The objective of this study was t...
journal_title：Research in developmental disabilities
pub_type： 杂志文章
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更新日期：2011-09-01 00:00:00
abstract：:This study evaluated the use of the MacKinnon splint upon grasp skills in three children, ages 2 1/2 to 7 1/2, with spastic hemiplegia. The MacKinnon splint was sequentially introduced in a multiple baseline design across subjects. The results indicated improvement in each child's grasp of eight different, randomly pr...
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pub_type： 杂志文章
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