Photosensitization by Photofrin II delivered to WI26VA4 SV40-transformed human fibroblasts by low density lipoproteins: inhibition of lipid synthesis and fatty acid uptake.

abstract：:The effect of pretreatment with vitamin E on cytotoxicity, DNA single strand breaks, and chromosomal aberrations as well as on mutation induced by ultraviolet-B light (UV-B) was investigated in Chinese hamster V-79 cells. Cellular pretreatment with non-toxic levels of 25 microM alpha-tocopherol succinate (vitamin E) f...

journal_title：Photochemistry and photobiology

authors： Sugiyama M,Tsuzuki K,Matsumoto K,Ogura R

更新日期：1992-07-01 00:00:00

abstract：:Microscopic fluorescence photometry incorporating a light-sensitive thermo-electrically cooled charge-coupled device (CCD) camera was employed to investigate the fluorescence distribution of 5-aminolevulinic acid (ALA)-induced porphyrins in 22 patients with a total number of 52 noduloulcerative basal cell carcinomas (...

journal_title：Photochemistry and photobiology

authors： Peng Q,Warloe T,Moan J,Heyerdahl H,Steen HB,Nesland JM,Giercksky KE

更新日期：1995-11-01 00:00:00

abstract：:The photostability of drugs administered topically on unprotected skin is a complex phenomenon that could be connected with the loss of activity or, rather rarely, the occurrence of toxic degradation products. In this study, an in-depth investigation of the photostability of terbinafine, in both solutions and formulat...

journal_title：Photochemistry and photobiology

authors： Kryczyk-Poprawa A,Żmudzki P,Koczurkiewicz P,Pękala E,Hubicka U

更新日期：2019-07-01 00:00:00

abstract：:The production of vitamin D3 is a pharmaceutically relevant process, producing high added-value products. Precursors are extracts from vegetal origin but bearing mainly an E geometry in the 5,6 double bond. The synthesis of vitamin D3 (5-E-α-calcidol) with the correct Z stereochemistry in the 5,6 double bond from the ...

journal_title：Photochemistry and photobiology

authors： Estruch GA,Aramendía PF

更新日期：2012-07-01 00:00:00

abstract：:The photochemistry of Ru(bpy)(3)+2 in the presence of amines was investigated in water by laser flash photolysis. N,N'-Dimethylaniline and p-phenylenediamine quench the luminescent metal to ligand charge transfer (MLCT) excited state of the complex by an electron transfer reaction that produces the semireduced form Ru...

journal_title：Photochemistry and photobiology

authors： Rivarola CR,Bertolotti SG,Previtali CM

更新日期：2006-01-01 00:00:00

abstract：:Use of near infrared instead of visible light would markedly improve tissue penetration, making larger tumors candidates for photochemotherapy. Because common photesensitizers exhibit virtually no absorption in this wavelength region, conditions are required where the simultaneous action of two photons is possible. He...

journal_title：Photochemistry and photobiology

authors： Lenz P

更新日期：1995-08-01 00:00:00

abstract：:Eumelanin (brown/black melanin) and pheomelanin (red/yellow melanin) in human hair can be quantified using chemical methods or approximated using spectrophotometric methods. Chemical methods consume greater resources, making them less attractive for epidemiological studies. This investigation sought to identify the sp...

journal_title：Photochemistry and photobiology

authors： Shekar SN,Duffy DL,Frudakis T,Montgomery GW,James MR,Sturm RA,Martin NG

更新日期：2008-05-01 00:00:00

abstract：:We have previously demonstrated the ability of UVC (254 nm) radiation to induce asynchronous polyoma replication in rat fibroblast cells (H3 line) that contain an integrated copy of polyoma virus. In the present study we show that general purpose lamps can induce polyoma replication in these cells as well. The amount ...

journal_title：Photochemistry and photobiology

authors： Rutberg SE,Ronai Z

更新日期：1993-08-01 00:00:00

abstract：:Recent developments in optical technologies have the potential to improve the speed and accuracy of screening and diagnosis of curable precancerous lesions and early cancer, thereby decreasing the costs of detection and management of epithelial malignancies. The development of molecular-specific contrast agents for ma...

journal_title：Photochemistry and photobiology

authors： Hsu ER,Anslyn EV,Dharmawardhane S,Alizadeh-Naderi R,Aaron JS,Sokolov KV,El-Naggar AK,Gillenwater AM,Richards-Kortum RR

更新日期：2004-03-01 00:00:00

abstract：:Photodynamic therapy (PDT) is an established therapeutic modality that uses nonionizing near-infrared light to activate photocytotoxicity of endogenous or exogenous photosensitizers (PSs). An ongoing avenue of cancer research involves leveraging PDT to stimulate antitumor immune responses; however, these effects appea...

journal_title：Photochemistry and photobiology

authors： Kercher EM,Nath S,Rizvi I,Spring BQ

更新日期：2020-03-01 00:00:00

abstract：:UV radiation is a potent DNA damaging agent and a known inducer of skin cancer in experimental animals. There is excellent scientific evidence to indicate that most non-melanoma human skin cancers are induced by repeated exposure to sunlight. UV radiation is unique in that it induces DNA damage that differs from the l...

journal_title：Photochemistry and photobiology

authors： Ananthaswamy HN,Pierceall WE

更新日期：1990-12-01 00:00:00

abstract：:Pharaonis phoborhodopsin (ppR or sensory rhodopsin II) is a negative phototaxis receptor of Natronomonas pharaonis, and forms a complex, which transmits the photosignal into cytoplasm, with its cognate transducer (pHtrII). We examined a possible local dynamics change of ppR and its D75N mutant complexed with pHtrII, u...

journal_title：Photochemistry and photobiology

authors： Kawamura I,Yoshida H,Ikeda Y,Yamaguchi S,Tuzi S,Saitô H,Kamo N,Naito A

更新日期：2008-07-01 00:00:00

abstract：:On direct photoexcitation, subpicosecond time-resolved absorption spectroscopy revealed that the 1B(u)-type singlet excited state of all-trans-lycopene in chloroform was about seven times more efficient than all-trans-beta-carotene in generating the radical cation. The time constant of radical cation generation from t...

journal_title：Photochemistry and photobiology

authors： Han RM,Wu YS,Feng J,Ai XC,Zhang JP,Skibsted LH

更新日期：2004-09-01 00:00:00

abstract：:Cis-urocanic acid (UCA), formed in the epidermis by UV irradiation of trans-UCA, has been implicated as a mediator of the immunosuppression induced by UV exposure of the skin. This review covers recent work in which the wavelength dependence of cis-UCA formation, the interaction of UCA isomers with DNA, the effects of...

journal_title：Photochemistry and photobiology

authors： Norval M,Gibbs NK,Gilmour J

更新日期：1995-08-01 00:00:00

abstract：:Antisense oligodeoxynucleotides directed against a 24-mer RNA derived from the long terminal repeat (LTR) region of HIV were linked to proto- and methylpyrroporphyrin and their zinc derivatives. The oligonucleotide-porphyrin conjugates were tested for their ability to induce photodamage on the target RNA. Upon hybridi...

journal_title：Photochemistry and photobiology

authors： Mastruzzo L,Woisard A,Ma DD,Rizzarelli E,Favre A,Le Doan T

更新日期：1994-10-01 00:00:00

abstract：:Low-level light therapy has been used in health care as a therapeutic strategy for different diseases. However, its effects on cancer are controversial. This work evaluated the effects of three energies on breast cancer-bearing mice after a single red light-emitting diode (LED) irradiation. 4T1 cells were inoculated i...

journal_title：Photochemistry and photobiology

authors： Pereira ST,Silva CR,Nuñez SC,Ribeiro MS

更新日期：2020-10-03 00:00:00

abstract：:It has been proposed that photodegradation of folates may be the reason for the pigmentation of races living under high fluence rates of ultraviolet radiation. The photodegradation of folic acid (FA) induced by ultraviolet-A (UV-A) radiation, in solution and in the presence of human serum albumin (HSA), was studied wi...

journal_title：Photochemistry and photobiology

authors： Vorobey P,Steindal AE,Off MK,Vorobey A,Moan J

更新日期：2006-05-01 00:00:00

abstract：:The significance of human cutaneous pigmentation lies in its protective role against sun-induced DNA damage and photocarcinogenesis. Fair skin and red hair are characterized by a low eumelanin to pheomelanin ratio, and have been associated with increased risk of skin cancer. Cutaneous pigmentation is a complex genetic...

journal_title：Photochemistry and photobiology

authors： Dessinioti C,Antoniou C,Katsambas A,Stratigos AJ

更新日期：2011-09-01 00:00:00

abstract：:This research examines the behavior of ground-level solar UV radiation as measured by eight broadband meters in the continental United States during the period from late 1994 to late 1998. The goal is to define the variability that occurs in UV irradiance over time scales ranging from one to several years. The monthly...

journal_title：Photochemistry and photobiology

authors： Frederick JE,Slusser JR,Bigelow DS

更新日期：2000-10-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) plays essential roles in the normal biological processes and the treatment of cancer and skin diseases. Considering its photosensitive property, many studies have been focused on the photochemistry of ATRA. In this study, we investigated the transient phenomena in the laser flash photoly...

journal_title：Photochemistry and photobiology

authors： Li K,Wang M,Wang T,Sun D,Zhu R,Sun X,Wu X,Wang SL

更新日期：2013-09-01 00:00:00

abstract：:Ring-fused retinal analogs were designed to examine the hula-twist mode of the photoisomerization of the 9-cis retinylidene chromophore. Two 9-cis retinal analogs, the C11-C13 five-membered ring-fused and the C12-C14 five-membered ring-fused retinal derivatives, formed the pigments with opsin. The C11-C13 ring-fused a...

journal_title：Photochemistry and photobiology

authors： Hirano T,Lim IT,Kim DM,Zheng XG,Yoshihara K,Oyama Y,Imai H,Shichida Y,Ishiguro M

更新日期：2002-12-01 00:00:00

abstract：:Evidence is mounting that UV-B and UV-A radiation affect skin differently in responses as diverse as erythema and elastosis. We found in this study that collagen metabolism was also differentially affected. Albino hairless mice were irradiated with two UV-A sources: (1) UVASUN 3000 (340-400 nm) for cumulative exposure...

journal_title：Photochemistry and photobiology

authors： Kligman LH,Gebre M

更新日期：1991-08-01 00:00:00

abstract：:Photodynamic therapy (PDT) oxygen consumption, clonogenic cell survival, fluorescence photobleaching and photoproduct formation were investigated during benzoporphyrin derivative monoacid (BPD-MA)-PDT of MAT-LyLu cells in vitro. Cells were incubated with BPD-MA concentrations of 0.1, 0.5 or 2.5 μg mL(-1) for 2 h and t...

journal_title：Photochemistry and photobiology

authors： Weston MA,Patterson MS

更新日期：2011-09-01 00:00:00

abstract：:The broad-band normal incidence UVB beam radiation has been measured at Neve Zohar, Dead Sea basin, using a prototype tracking instrument composed of a Model 501A UV-Biometer mounted on an Eppley Solar Tracker Model St-1. The diffuse and beam fraction of the solar global UVB radiation have been determined using the co...

journal_title：Photochemistry and photobiology

authors： Kudish AI,Harari M,Evseev EG

更新日期：2011-01-01 00:00:00

abstract：:UVB radiation contributes to both direct and indirect damage to the skin including the generation of free radicals and reactive oxygen species (ROS), inflammatory responses, immunosuppression and gene mutations, which can ultimately lead to photocarcinogenesis. A plant-derived flavonoid, baicalin, has been shown to ha...

journal_title：Photochemistry and photobiology

authors： Min W,Ahmad I,Chang ME,Burns EM,Qian Q,Yusuf N

更新日期：2015-11-01 00:00:00

abstract：:The two-photon photolysis of liquid CCl4 with 25 ps pulses of 266 nm light has been studied and compared with similar studies with high energy radiation. Both neutral and ionic species are produced from excited states and ionization. The emphasis of the study is on the ionic processes, while some data related to excit...

journal_title：Photochemistry and photobiology

authors： Zhang G,Thomas JK

更新日期：2006-01-01 00:00:00

abstract：:Photodynamic therapy (PDT) of cancer induces oxidative stress, which intervenes in the expression of cytokines by tumor cells. The cytokines might have either a positive or a negative impact on tumor eradication. Here, we studied the expression of cytokines vascular endothelial growth factor (VEGF) and interleukin-1al...

journal_title：Photochemistry and photobiology

authors： Dabkeviciene D,Sasnauskiene A,Leman E,Kvietkauskaite R,Daugelaviciene N,Stankevicius V,Jurgelevicius V,Juodka B,Kirveliene V

更新日期：2012-03-01 00:00:00

abstract：:The infrared spectrum of monomeric unsubstituted coumarin (C9H6O2; 2H-1-benzopyran-2-one), isolated in solid argon at 10 K is presented and assigned. The UV-induced (lambda>200 nm) unimolecular photochemistry of the matrix-isolated compound was studied experimentally. Three main photoreactions were observed: (a) decar...

journal_title：Photochemistry and photobiology

authors： Kuş N,Breda S,Reva I,Tasal E,Ogretir C,Fausto R

更新日期：2007-09-01 00:00:00

abstract：:There are controversial reports in the literature concerning the reactivity of singlet oxygen ((1)O(2)) with the redox probe 2',7'-dichlorodihydrofluorescein (DCFH). By carefully preparing solutions in which (1)O(2) is quantitatively generated in the presence of DCFH, we were able to show that the formation rate of th...

journal_title：Photochemistry and photobiology

authors： Daghastanli NA,Itri R,Baptista MS

更新日期：2008-09-01 00:00:00

abstract：:In an attempt to develop an efficient chemotherapeutic agent targeted at malignant cells that express receptors to gonadotropin releasing hormone (GnRH) we coupled [D-Lys6]GnRH covalently to an emodin derivative, i.e. emodic acid (Emo) to yield [D-Lys6(Emo)]GnRH. Emodin is a naturally occurring anthraquinone which is ...

journal_title：Photochemistry and photobiology

authors： Rahimipour S,Bilkis I,Péron V,Gescheidt G,Barbosa F,Mazur Y,Koch Y,Weiner L,Fridkin M

更新日期：2001-08-01 00:00:00