Diffuse and localized tenosynovial giant cell tumor and pigmented villonodular synovitis: a clinicopathologic and flow cytometric DNA analysis.

abstract：:Meconium-associated vascular necrosis (MAVN) is a histological abnormality of human placental chorionic vessels that is associated with poor neonatal outcome. We tested the hypothesis that MAVN shows apoptosis in the walls of chorionic vessels. Archival placental specimens with MAVN (n = 5) were compared with specimen...

journal_title：Human pathology

authors： King EL,Redline RW,Smith SD,Kraus FT,Sadovsky Y,Nelson DM

更新日期：2004-04-01 00:00:00

abstract：:Enteroendocrine cell dysgenesis was observed in 3 patients with intestinal failure of unknown cause. Enteroendocrine cell dysgenesis is a congenitally acquired life-threatening malabsorptive condition with a unique clinical phenotype paired with a histologically identifiable disease pattern. Two cases were first prese...

journal_title：Human pathology

authors： Cortina G,Smart CN,Farmer DG,Bhuta S,Treem WR,Hill ID,Martín MG

更新日期：2007-04-01 00:00:00

abstract：:A study of so-called gelatinous transformation of the bone marrow in 14 patients is presented. The condition is characterized by the presence of extracellular "gelatinous" material, fat atrophy, and associated focal marrow hypoplasia and is often mistaken as representing edema, necrosis, or amyloid. Histochemical stud...

journal_title：Human pathology

authors： Seaman JP,Kjeldsberg CR,Linker A

更新日期：1978-11-01 00:00:00

abstract：:SPARC (secreted protein acidic and rich in cysteine, also called osteonectin, BM-40, and 43K protein) is a matricellular protein and is associated with cell-matrix interactions during cell proliferation and extracellular remodeling. It is also implicated in the neovascularization, invasion, and metastasis of human mal...

journal_title：Human pathology

authors： Sakai N,Baba M,Nagasima Y,Kato Y,Hirai K,Kondo K,Kobayashi K,Yoshida M,Kaneko S,Kishida T,Kawakami S,Hosaka M,Inayama Y,Yao M

更新日期：2001-10-01 00:00:00

abstract：:Angiogenesis is important for tumor growth and progress, and the intratumor density of microvessels is a significant prognostic factor in many tumor types. The role in thyroid cancer has not been well studied, and we therefore examined a series of 128 papillary carcinomas with respect to microvessel density (MVD) and ...

journal_title：Human pathology

authors： Akslen LA,Livolsi VA

更新日期：2000-04-01 00:00:00

abstract：:Cholangiocarcinoma of intrahepatic and extrahepatic bile ducts has a multistep carcinogenesis. Two premalignant lesions have been suggested for invasive cholangiocarcinoma: biliary intraepithelial neoplasia and intraductal papillary neoplasm of the bile duct. How the carcinogenetic process differs between biliary intr...

journal_title：Human pathology

authors： Nakanishi Y,Zen Y,Kondo S,Itoh T,Itatsu K,Nakanuma Y

更新日期：2008-08-01 00:00:00

abstract：:Sections of synovium from 393 operations on diseased joints were re-examined without knowledge of the clinical findings. Specimens were scored for each of 37 histopathologic features. Independently, patients were assigned to one of 10 diagnostic groups after review of all available clinical data. Computer analysis rev...

journal_title：Human pathology

authors： Cooper NS,Soren A,McEwen C,Rosenberger JL

更新日期：1981-04-01 00:00:00

abstract：:Kaposi's sarcoma (KS) is a pleomorphic spindle cell lesion whose incidence has markedly increased among patients infected with the human immunodeficiency virus (HIV), especially among those whose primary risk factor is homo/bisexual transmission. The question as to whether KS is even a true neoplasm still remains larg...

journal_title：Human pathology

authors： Lee WA,Hutchins GM

更新日期：1992-03-01 00:00:00

abstract：:CRABP-II, a retinoic acid binding protein, shuffles retinoic acid from cytoplasm into nucleus and forms a complex with nuclear retinoic acid receptor to facilitate transcriptional activities of retinoic acid. In this study, we studied the expression patterns of CRABP-II in pancreatic ductal adenocarcinoma (PDAC) compa...

journal_title：Human pathology

authors： Xiao W,Hong H,Awadallah A,Yu S,Zhou L,Xin W

更新日期：2014-06-01 00:00:00

abstract：:Twenty-five cases of Crohn's disease confined to the appendix were reported in eight hospitals in Israel during a 15-year period. Review of the histologic slides confirmed the diagnosis in 22 cases. Re-evaluation of these 22 patients included physical examination and radiologic studies of the small and large bowel. Re...

journal_title：Human pathology

authors： Ariel I,Vinograd I,Hershlag A,Olsha O,Argov S,Klausner JM,Rabau MY,Freund U,Rosenmann E

更新日期：1986-11-01 00:00:00

abstract：:A case of myocardial hyperplasia with numerous mitotic figures, caterpillar nuclei, and an abnormal DNA ploidy pattern is described in an 8-day-old full-term baby with uneventful gestation and sudden death. ...

journal_title：Human pathology

authors： Zerbini C,Weinberg DS,Perez-Atayde AR

更新日期：1992-12-01 00:00:00

abstract：:We report here an exceptional pattern of atypical lentiginous melanocytic proliferation within an adenoma, leading to focal lamina propria infiltration and pulmonary metastasis, which was considered as primary colonic mucosal melanoma (MM) in a Caucasian patient. Such case illustrates the diagnosis criteria required t...

journal_title：Human pathology

authors： Furudoï A,Caumont C,Dutriaux C,Cappellen D,Goussot JF,Vergier B,Merlio C,Barberis C,Merlio JP,Gros A

更新日期：2016-02-01 00:00:00

abstract：:The immunohistologic distribution of the basement membrane components, type IV collagen and laminin, was evaluated in 57 alcohol-fixed, paraffin-embedded tissue sections which demonstrated immunostaining patterns with antigen preservation similar to that of frozen tissue sections. Normal and hyperplastic squamous muco...

journal_title：Human pathology

authors： Sakr WA,Zarbo RJ,Jacobs JR,Crissman JD

更新日期：1987-10-01 00:00:00

abstract：:The aim of this study on a series of biopsies diagnosed as normal, metaplastic, low-grade squamous intraepithelial lesions (LSILs), and high-grade squamous intraepithelial lesions (HSILs) was dual: to determine the chronology of cell cycle and proliferation abnormalities after human papillomavirus infection during the...

journal_title：Human pathology

authors： Lorenzato M,Caudroy S,Bronner C,Evrard G,Simon M,Durlach A,Birembaut P,Clavel C

更新日期：2005-10-01 00:00:00

abstract：:Astrocytoma grade IV (glioblastoma multiforme) is the most common and most malignant tumor of the central nervous system and is currently noncurable. Here, we have examined a population-based cohort of 47 patients with grade IV astrocytoma, who underwent tumor surgery at Sahlgrenska University Hospital in Sweden and w...

journal_title：Human pathology

authors： Skalli O,Wilhelmsson U,Orndahl C,Fekete B,Malmgren K,Rydenhag B,Pekny M

更新日期：2013-10-01 00:00:00

abstract：:Lymphoplasmacytic infiltrates in the breast, a modified skin appendage, include lymphocytic lobulitis, other nonspecific benign proliferations, and mucosa-associated lymphoid tissue (MALT)-type lymphoma. Distinguishing these entities, all of which may be B-cell rich and may have associated sclerosis, can be difficult....

journal_title：Human pathology

authors： Berg AN,Soma L,Clark BZ,Swerdlow SH,Roth CG

更新日期：2015-08-01 00:00:00

abstract：:Laminin and collagen have been studied in several tumor types and their immunomorphological expression correlated with tumor morphogenesis, local invasiveness, and metastatic behavior. In a series of 53 cases of pleomorphic adenomas (PA) and 16 cases of carcinomas ex-pleomorphic adenoma (Ca ex-PA), we investigated by ...

journal_title：Human pathology

authors： Félix A,Rosa JC,Fonseca I,Cidadão A,Soares J

更新日期：1999-08-01 00:00:00

abstract：:Eight cases of primary mesenchymal renal tumor in infants under one year of age were studied. The patients' ages ranged from one day to seven months; all but one were diagnosed within the first three months of life. There were four typical congenital mesoblastic nephromas. Two malignant mesenchymal, one intermediate c...

journal_title：Human pathology

authors： Gonzalez-Crussi F,Sotelo-Avila C,Kidd JM

更新日期：1981-01-01 00:00:00

abstract：:Seven cases in which interstitial fibrosis developed in patients who had acute interstitial pneumonia were studied ultrastructurally to elucidate the pathogenesis of the interstitial thickening seen by light microscopy. Interstitial fibrosis is generally thought to result from fibroblast proliferation and collagen dep...

journal_title：Human pathology

authors： Katzenstein AL

更新日期：1985-10-01 00:00:00

abstract：:We report a case of a newborn female with a rare tumor, a congenital sarcoma, presenting as an abdominal mass. Laparotomy demonstrated the tumor arising from the wall of the terminal ileum. Histologically, the tumor tissue was indistinguishable from clear cell sarcoma of the kidney and was composed of proliferating ce...

journal_title：Human pathology

authors： Kataoka Y,Shimada H,Sugimoto T,Mine H,Hachitanda Y,Doi Y,Sawada T,Weeks DA

更新日期：1993-09-01 00:00:00

abstract：:We describe a case of a complete hydatidiform mole with a coexistent embryo. A 19-year-old Hispanic woman presented with an intrauterine pregnancy at 7 weeks gestational age. An ultrasound evaluation at that time showed a gestational sac and fetal heart activity was observed. Four weeks later, subsequent ultrasound st...

journal_title：Human pathology

authors： Baergen RN,Kelly T,McGinniss MJ,Jones OW,Benirschke K

更新日期：1996-07-01 00:00:00

abstract：:Sneddon's syndrome is a potentially fatal arterio-occlusive disorder characterized by generalized livedo racemosa and cerebrovascular lesions. Skin biopsies often fail to yield diagnostic arterial lesions. In the present series, affected vessels were found in skin biopsies from 12 of 15 patients with Sneddon's syndrom...

journal_title：Human pathology

authors： Zelger B,Sepp N,Schmid KW,Hintner H,Klein G,Fritsch PO

更新日期：1992-06-01 00:00:00

abstract：:Clinicopathological and cytogenetic studies were performed on specimens from 43 patients with CD30-positive anaplastic large cell lymphoma (ALCL). All patients were born and lived in a human T-cell lymphotropic virus (HTLV)-I endemic area. Twenty-one patients (48.8%) had serum anti-HTLV-I antibody suggesting the prese...

journal_title：Human pathology

authors： Takeshita M,Ohshima K,Akamatsu M,Ohgami A,Kikuchi M,Suzumiya J,Uike N,Okamura T,Nakayama J

更新日期：1995-06-01 00:00:00

abstract：:Literature on BRCA1-associated protein 1 (BAP1) expression status in well-differentiated papillary mesothelioma (WDPM) is limited. In the present study, we examined the prevalence of BAP1 loss in WDPM by immunohistochemistry with clinical correlation, along with CDKN2A deletion status by fluorescence in situ hybridiza...

journal_title：Human pathology

authors： Lee HE,Molina JR,Sukov WR,Roden AC,Yi ES

更新日期：2018-09-01 00:00:00

abstract：:Three ovarian thecomas were studied by ultrastructural and immunohistochemical techniques. In each tumor, a small number of tumor cells stained for estradiol. Vacuolated as well as plump non-vacuolated tumor cells were positive, but spindle-shaped cells were negative. Ultrastructural examination showed two principle c...

journal_title：Human pathology

authors： Gaffney EF,Majmudar B,Hewan-Lowe K

更新日期：1984-02-01 00:00:00

abstract：:Gene amplification is a common event in breast cancer, and identifies actual and potential targets of molecular therapy. The aim of the present study was to determine the amplification status of 22 genes that are reportedly frequently amplified in breast cancers. An archive of 322 formalin-fixed and paraffin-embedded ...

journal_title：Human pathology

authors： Ooi A,Inokuchi M,Horike SI,Kawashima H,Ishikawa S,Ikeda H,Nakamura R,Oyama T,Dobashi Y

更新日期：2019-03-01 00:00:00

abstract：:The cell of origin of parafollicular (monocytoid) B cell lymphoma (PBCL), splenic marginal zone lymphoma (SMZL), and hairy cell leukemia (HCL) is controversial. To better understand the relationship between these low-grade B-cell neoplasms, we analyzed the nucleotide sequences of the rearranged immunoglobulin heavy (I...

journal_title：Human pathology

authors： Miranda RN,Cousar JB,Hammer RD,Collins RD,Vnencak-Jones CL

更新日期：1999-03-01 00:00:00

abstract：:We reviewed open lung biopsies from 35 patients with Wegener's (pathergic) granulomatosis in order to study the histogenesis of the pulmonary lesions and to identify the early lesions. The process of pathergic necrosis is fundamental in the production of extravascular and vascular lesions and was divided into micronec...

journal_title：Human pathology

authors： Mark EJ,Matsubara O,Tan-Liu NS,Fienberg R

更新日期：1988-09-01 00:00:00

abstract：:Primitive neuroectodermal tumors are morphologically similar malignant tumors arising in intracranial and peripheral sites of the nervous system, showing varying degrees of cellular differentiation with a tendency to disseminate along cerebrospinal fluid pathways. They occur primarily in children and young adults. Und...

journal_title：Human pathology

authors： Becker LE,Hinton D

更新日期：1983-06-01 00:00:00

abstract：:Mucus-filled cystic tumors of low or borderline malignant potential, well recognized in ovary and appendix, have received little attention in the lung. We present data on 11 patients, all of whom had solitary pulmonary nodules resected in which mucus was the major histologic component. Prognosis appears good; no patie...

journal_title：Human pathology

authors： Graeme-Cook F,Mark EJ

更新日期：1991-02-01 00:00:00