T cells expressing the gamma delta T-cell receptor potentiate coxsackievirus B3-induced myocarditis.

abstract：:Interaction between viral proteins is necessary for viral replication and viral particle assembly. We used the yeast two-hybrid assay to identify interactions among all the mature proteins of the hepatitis C virus. The interaction between NS3 and NS3 was one of the strongest viral protein-protein interactions detected...

journal_title：Journal of virology

authors： Khu YL,Koh E,Lim SP,Tan YH,Brenner S,Lim SG,Hong WJ,Goh PY

更新日期：2001-01-01 00:00:00

abstract：:Viral infectivity factor (Vif) is required for lentivirus fitness and pathogenicity, except in equine infectious anemia virus (EIAV). Vif enhances viral infectivity by a Cullin5-Elongin B/C E3 complex to inactivate the host restriction factor APOBEC3. Core-binding factor subunit beta (CBF-β) is a cell factor that was ...

journal_title：Journal of virology

authors： Ai Y,Zhu D,Wang C,Su C,Ma J,Ma J,Wang X

更新日期：2014-10-01 00:00:00

abstract：:The treatment of bacteriophage T4D with 2-hydroxy-5-nitrobenzyl bromide, a specific reagent for alkylating the indole ring of tryptophan residues, converts these particles from a cofactor-independent form to a cofactor-sensitive form. These treated T4D particles phenotypically resemble T4B particles in certain respect...

journal_title：Journal of virology

authors： Gamow RI,Kozloff LM

更新日期：1968-05-01 00:00:00

abstract：:The prevailing hypothesis is that the intracellular site of budding of coronaviruses is determined by the localization of its membrane protein M (previously called E1). We tested this by analyzing the site of budding of four different coronaviruses in relation to the intracellular localization of their M proteins. Mou...

journal_title：Journal of virology

authors： Klumperman J,Locker JK,Meijer A,Horzinek MC,Geuze HJ,Rottier PJ

更新日期：1994-10-01 00:00:00

abstract：:The structural instability of inactivated foot-and-mouth disease virus (FMDV) hinders the development of vaccine industry. Here we found that some transition metal ions like Cu2+ and Ni2+ could specifically bind to FMDV capsids at capacities about 7089 and 3448 metal ions per capsid, respectively. These values are abo...

journal_title：Journal of virology

authors： Lin X,Yang Y,Song Y,Li S,Zhang X,Su Z,Zhang S

更新日期：2021-01-13 00:00:00

abstract：:Most eukaryotic initiation factors (eIFs) are required for internal translation initiation at the internal ribosome entry site (IRES) of picornaviruses. eIF4B is incorporated into ribosomal 48S initiation complexes with the IRES RNA of foot-and-mouth disease virus (FMDV). In contrast to the weak interaction of eIF4B w...

journal_title：Journal of virology

authors： Ochs K,Rust RC,Niepmann M

更新日期：1999-09-01 00:00:00

abstract：:A number of eucaryotic viruses have devised strategies to minimize the deleterious effects on protein synthesis caused by activation of the interferon-induced, double-stranded-RNA-activated protein kinase, P68. In a recent report, we described the down regulation of the P68 protein kinase in cells infected by human im...

journal_title：Journal of virology

authors： Roy S,Agy M,Hovanessian AG,Sonenberg N,Katze MG

更新日期：1991-02-01 00:00:00

abstract：:The localization of the adenovirus type 5 34-kDa E4 and 55-kDa E1B proteins was determined in the absence of other adenovirus proteins. When expressed by transfection in human, monkey, hamster, rat, and mouse cell lines, the E1B protein was predominantly cytoplasmic and typically was excluded from the nucleus. When ex...

journal_title：Journal of virology

authors： Goodrum FD,Shenk T,Ornelles DA

更新日期：1996-09-01 00:00:00

abstract：:The genome structure of a newly isolated sarcoma virus, Y73, was studied. Y73 is a defective, potent sarcomagenic virus and contains 4.8-kilobase (kb) RNA as its genome; in contrast, helper virus associated with Y73 had 8.5-kb RNA, similar to other avian leukemia viruses. Fingerprinting analysis these RNAs demonstrate...

journal_title：Journal of virology

authors： Yoshida M,Kawai S,Toyoshima K

更新日期：1981-05-01 00:00:00

abstract：:Precore and core proteins are two related co-carboxy-terminal proteins of hepatitis B virus. Precore protein contains the entire sequence of core protein plus an amino-terminal extension of 29 amino acid residues. Both proteins can display a common antigenic determinant known as core antigen (HBcAg). Clinically, HBcAg...

journal_title：Journal of virology

authors： Yeh CT,Liaw YF,Ou JH

更新日期：1990-12-01 00:00:00

abstract：:Hydroxyurea, an inhibitor of ribonucleotide reductase, blocks replication of vaccinia virus. However, when medium containing hydroxyurea and dialyzed serum was supplemented with deoxyadenosine, the block to viral reproduction was circumvented, provided that an inhibitor of adenosine deaminase was also present. Deoxygu...

journal_title：Journal of virology

authors： Slabaugh MB,Howell ML,Wang Y,Mathews CK

更新日期：1991-05-01 00:00:00

abstract：:The Sindbis virus minimal subgenomic mRNA promoter (spanning positions -19 to +5 relative to the subgenomic mRNA start site) is approximately three- to sixfold less active than the fully active -98 to +14 promoter region. We identified two elements flanking the -19 to +5 region which increase its transcription to leve...

journal_title：Journal of virology

authors： Wielgosz MM,Raju R,Huang HV

更新日期：2001-04-01 00:00:00

abstract：:We have previously reported that infection of 9- to 13-day-old chicken embryos with RAV-1 results in rapid development of a novel B-cell lymphoma in which proviral insertion has activated expression of the c-myb gene (E. Pizer and E. H. Humphries, J. Virol. 63:1630-1640, 1989). The biological properties of these B-cel...

journal_title：Journal of virology

authors： Pizer ES,Baba TW,Humphries EH

更新日期：1992-01-01 00:00:00

abstract：:Chaperone-enriched domains are formed in the nuclei of cells lytically infected with herpes simplex virus type 1 (HSV-1). These domains, called VICE, for virus induced chaperone enriched, contain Hsc70, Hsp70, Hsp40, Hsp90, polyubiquitinated proteins, and components of the proteasome machinery. Accumulating evidence i...

journal_title：Journal of virology

authors： Mathew SS,Della Selva MP,Burch AD

更新日期：2009-09-01 00:00:00

abstract：UNLABELLED:Herpes simplex virus 1 (HSV-1) most commonly causes recrudescent labial ulcers; however, it is also the leading cause of infectious blindness in developed countries. Previous research in animal models has demonstrated that the severity of HSV-1 ocular disease is influenced by three main factors: host innate ...

journal_title：Journal of virology

authors： Lee K,Kolb AW,Larsen I,Craven M,Brandt CR

更新日期：2016-08-26 00:00:00

abstract：:Molecular clones of closed circular DNA molecules of a mink cell focus-inducing murine leukemia virus (MCF-13 MuLV) were generated. Closed circular DNA molecules isolated from a Hirt extraction of recently infected NIH/3T3 cells were inserted at their unique EcoRI site into lambda gtWES.lambda B. Restriction endonucle...

journal_title：Journal of virology

authors： Yoshimura FK

更新日期：1982-07-01 00:00:00

abstract：:A majority of species B adenoviruses (Ads) use CD46 as their primary receptor; however, the precise mechanisms involved in the binding of different Ad types to CD46 have not been resolved. Although previous studies indicate close similarities between two members of species B2 Ads in their usage of CD46, our current in...

journal_title：Journal of virology

authors： Pache L,Venkataraman S,Reddy VS,Nemerow GR

更新日期：2008-08-01 00:00:00

abstract：:The adenovirus type 4 origins of replication are located at each end of the linear, protein-linked viral DNA molecule and consist of the terminal 18 bp of the viral genome. The sequence of the first 8 bp of the viral genome varies among different adenovirus serotypes, but the sequence from bp 9 to 18 is conserved in a...

journal_title：Journal of virology

authors： Temperley SM,Burrow CR,Kelly TJ,Hay RT

更新日期：1991-09-01 00:00:00

abstract：:Influenza A viruses (IAVs) remain a significant public health threat, causing more than 300,000 hospitalizations in the United States during the 2015-2016 season alone. While only a few IAVs of avian origin have been associated with human infections, the ability of these viruses to cause zoonotic infections further in...

journal_title：Journal of virology

authors： Obadan AO,Santos J,Ferreri L,Thompson AJ,Carnaccini S,Geiger G,Gonzalez Reiche AS,Rajão DS,Paulson JC,Perez DR

更新日期：2019-03-05 00:00:00

abstract：:Biological and genetic variability is a prominent feature of human immunodeficiency virus (HIV) strains, especially in tropism, syncytium formation, and replicative capacity. To determine whether there were variable host cell effects on HIV replication in monocytes, three different strains of low-passage-number monocy...

journal_title：Journal of virology

authors： Chang J,Naif HM,Li S,Sullivan JS,Randle CM,Cunningham AL

更新日期：1996-11-01 00:00:00

abstract：:Myeloblastosis-associated virus (MAV)-2(0), a virus which was derived from avian myeloblastosis virus and induced a high incidence of osteopetrosis, was compared with avian lymphomatosis virus 5938, a recent field isolate which induced a high incidence of lymphomatosis. The following information was obtained. (i) MAV-...

journal_title：Journal of virology

authors： Smith RE,Davids LJ,Neiman PE

更新日期：1975-01-01 00:00:00

abstract：:Due to the biological significance of the carbohydrate component of the human immunodeficiency virus type 1 (HIV-1) glycoproteins in viral pathogenesis, the glycosylation step constitutes an attractive target for anti-HIV therapy. Cyanovirin N (CV-N), which specifically targets the high-mannose (HM) glycans on gp120, ...

journal_title：Journal of virology

authors： Witvrouw M,Fikkert V,Hantson A,Pannecouque C,O'keefe BR,McMahon J,Stamatatos L,de Clercq E,Bolmstedt A

更新日期：2005-06-01 00:00:00

abstract：:The neutralizing activities of polyclonal antibodies and monoclonal antibodies (MAbs) obtained by immunization of mice with L1 virus-like particles (VLPs) were investigated by using pseudovirion infectivity assays for human papillomavirus type 16 (HPV-16), HPV-31, HPV-33, HPV-45, HPV-58, and HPV-59 to obtain a better ...

journal_title：Journal of virology

authors： Combita AL,Touzé A,Bousarghin L,Christensen ND,Coursaget P

更新日期：2002-07-01 00:00:00

abstract：:Utilization of internal ribosome entry segment (IRES) structures in the 5' noncoding region (5'NCR) of picornavirus RNAs for initiation of translation requires a number of host cell factors whose distribution may vary in different cells and whose requirement may vary for different picornaviruses. We have examined the ...

journal_title：Journal of virology

authors： Graff J,Cha J,Blyn LB,Ehrenfeld E

更新日期：1998-12-01 00:00:00

abstract：:We evaluated the ability of human coronaviruses to infect primary cultures of human neural cells. Double immunofluorescence with antibodies to virus and cell markers showed infection of fetal astrocytes and of adult microglia and astrocytes by strain OC43. RNA amplification revealed infection of fetal astrocytes, adul...

journal_title：Journal of virology

authors： Bonavia A,Arbour N,Yong VW,Talbot PJ

更新日期：1997-01-01 00:00:00

abstract：:The novel low-pathogenic avian influenza A H7N9 viruses (LPAI H7N9 viruses) have been a threat to public health since their emergence in 2013 because of the high rates of mortality and morbidity that they cause. Recently, highly pathogenic variants of these avian influenza A H7N9 viruses (HPAI H7N9 viruses) have emerg...

journal_title：Journal of virology

authors： Yang L,Zhu W,Li X,Chen M,Wu J,Yu P,Qi S,Huang Y,Shi W,Dong J,Zhao X,Huang W,Li Z,Zeng X,Bo H,Chen T,Chen W,Liu J,Zhang Y,Liang Z,Shi W,Shu Y,Wang D

更新日期：2017-11-14 00:00:00

abstract：:The genome of varicella-zoster virus (VZV) is a linear, double-stranded molecule of DNA composed of a long (L) region covalently linked to a short (S) region. The S region is capable of inverting relative to a fixed orientation of the L region, giving rise to two equimolar populations. We have investigated other forms...

journal_title：Journal of virology

authors： Kinchington PR,Reinhold WC,Casey TA,Straus SE,Hay J,Ruyechan WT

更新日期：1985-10-01 00:00:00

abstract：:We have devised an enrichment scheme for the isolation of export-competent derivatives of pseudorabies virus glycoprotein gIII signal peptide mutants. Enrichment is based upon a growth advantage imparted upon gIII-containing virions compared with virions lacking the glycoprotein. Each of identified derivatives suppres...

journal_title：Journal of virology

authors： Powers L,Ryan P

更新日期：1994-05-01 00:00:00

abstract：:Processing of dengue virus type 2 polyprotein precursor NS3-NS4A-NS4B-NS5 could be mediated by the catalytically active NS3 protease domain and NS2B in trans at the dibasic sites NS3-NS4A and NS4B-NS5. Subcellular localization of the unprocessed precursor NS3-NS4A-NS4B-NS5 showed that it was confined to a distinct sub...

journal_title：Journal of virology

authors： Zhang L,Mohan PM,Padmanabhan R

更新日期：1992-12-01 00:00:00

abstract：:Genetic and phylogenetic analyses suggest that the pandemic H1N1/2009 virus was derived from well-established swine influenza lineages; however, there is no convincing evidence that the pandemic virus was generated from a direct precursor in pigs. Furthermore, the evolutionary dynamics of influenza virus in pigs have ...

journal_title：Journal of virology

authors： Wei K,Sun H,Sun Z,Sun Y,Kong W,Pu J,Ma G,Yin Y,Yang H,Guo X,Chang KC,Liu J

更新日期：2014-10-01 00:00:00