Independent evolution of monkeypox and variola viruses.

abstract：:The genome of the defective interfering (DI) mouse hepatitis virus DI-a carries a large open reading frame (ORF) consisting of ORF1a, ORF1b, and nucleocapsid sequences. To test whether this fusion ORF is important for DI virus replication, we constructed derivatives of the DI-a genome in which the reading frame was tr...

journal_title：Journal of virology

authors： de Groot RJ,van der Most RG,Spaan WJ

更新日期：1992-10-01 00:00:00

abstract：:Naked DNA vaccines expressing the prM and E genes of two tick-borne flaviviruses, Russian spring summer encephalitis (RSSE) virus and Central European encephalitis (CEE) virus were evaluated in mice. The vaccines were administered by particle bombardment of DNA-coated gold beads by Accell gene gun inoculation. Two imm...

journal_title：Journal of virology

authors： Schmaljohn C,Vanderzanden L,Bray M,Custer D,Meyer B,Li D,Rossi C,Fuller D,Fuller J,Haynes J,Huggins J

更新日期：1997-12-01 00:00:00

abstract：:Rat (3Y1) and hamster embryo brain cells were transformed by wild-type adenovirus type 12 or the DNA-minus temperature-sensitive mutant ts401. The ts401-transformed 3Y1 cells, but not the wild-type transformants, displayed a temperature-sensitive response with respect to the following characteristics of the transforme...

journal_title：Journal of virology

authors： Ledinko N,Schaeufele J,Soorma O

更新日期：1979-01-01 00:00:00

abstract：:It is well established that host genetics, especially major histocompatibility complex (MHC) genes, are important determinants of human immunodeficiency virus disease progression. Studies with simian immunodeficiency virus (SIV)-infected Indian rhesus macaques have associated Mamu-B*17 with control of virus replicatio...

journal_title：Journal of virology

authors： Wojcechowskyj JA,Yant LJ,Wiseman RW,O'Connor SL,O'Connor DH

更新日期：2007-01-01 00:00:00

abstract：:Recombinant rotavirus (RV) with cDNA-derived chimeric VP4 was generated using recently developed reverse genetics for RV. The rescued virus, KU//rVP4(SA11)-II(DS-1), contains SA11 (simian RV strain, G3P[2])-based VP4, in which a cross-reactive neutralization epitope (amino acids 381 to 401) on VP5* is replaced by the ...

journal_title：Journal of virology

authors： Komoto S,Kugita M,Sasaki J,Taniguchi K

更新日期：2008-07-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) infection eliminates production of type I interferons (IFNs) in host cells, which triggers an antiviral immune response through the induction of downstream IFN-stimulated genes (ISGs), thus escaping the fate of host-mediated clearance. The IFN-induced transme...

journal_title：Journal of virology

authors： Zhang A,Duan H,Zhao H,Liao H,Du Y,Li L,Jiang D,Wan B,Wu Y,Ji P,Zhou EM,Zhang G

更新日期：2020-11-23 00:00:00

abstract：:By pretreating simian virus 40-infected BSC-1 cells with glucosamine, [(3)H]uridine labeling of both cellular and viral RNA can be halted instantaneously by addition of cold uridine. We have studied the fate of pulse-labeled viral RNA from cells at 45 h postinfection under these conditions. During a 5-min period of la...

journal_title：Journal of virology

authors： Chiu NH,Radonovich MF,Thoren MM,Salzman NP

更新日期：1978-11-01 00:00:00

abstract：:HLA-B*57-mediated selection pressure leads to a typical escape pathway in human immunodeficiency virus type 1 (HIV-1) CD8 epitopes such as TW10. Whether this T242N pathway is shared by all clades remains unknown. We therefore assessed the nature of HLA-B*57 selection in a large, observational Kenyan cohort where clade...

journal_title：Journal of virology

authors： McKinnon LR,Capina R,Peters H,Mendoza M,Kimani J,Wachihi C,Kariri A,Kimani M,Richmond M,Kiazyk SK,Fowke KR,Jaoko W,Luo M,Ball TB,Plummer FA

更新日期：2009-12-01 00:00:00

abstract：:Initiation of reverse transcription of human immunodeficiency virus type 1 (HIV-1) occurs by extension from the 3' end of a cellular tRNA complexed to the primer binding site (PBS) located near the 5' end of the viral RNA genome. Although the PBSs for all naturally occurring HIV-1 viruses are complementary to the 3'-t...

journal_title：Journal of virology

authors： Kang SM,Zhang Z,Morrow CD

更新日期：1997-01-01 00:00:00

abstract：:Two human papillomavirus type 16 (HPV 16)-immortalized human keratinocyte cell lines (HPK) were shown to have retained the ability for differentiation after subcutaneous injection into nude mice. These properties were maintained even at late passage. HPK cells gave rise to transiently growing cysts which exhibited an ...

journal_title：Journal of virology

authors： Dürst M,Bosch FX,Glitz D,Schneider A,zur Hausen H

更新日期：1991-02-01 00:00:00

abstract：:Two panels of monoclonal antibodies (MAbs) specific for the influenza A virus PA and PB2 polypeptides have been obtained from mice immunized with denatured proteins produced in Escherichia coli. All MAbs (13 specific for the PA polypeptide and 8 specific for the PB2 protein) reacted to the corresponding influenza viru...

journal_title：Journal of virology

authors： Bárcena J,Ochoa M,de la Luna S,Melero JA,Nieto A,Ortín J,Portela A

更新日期：1994-11-01 00:00:00

abstract：:Cytotoxic CD8+ T lymphocytes (CTL) directed against the matrix protein pp65 are major effectors in controlling infection against human cytomegalovirus (HCMV), a persistent virus of the Betaherpesvirus family. We previously suggested that cross-presentation of pp65 by nonpermissive dendritic cells (DCs) could overcome ...

journal_title：Journal of virology

authors： Arrode G,Boccaccio C,Abastado JP,Davrinche C

更新日期：2002-01-01 00:00:00

abstract：:Human papillomaviruses (HPV) link their life cycles to epithelial differentiation and induce productive replication of viral DNA in suprabasal cells. Viral-DNA amplification requires cells to remain active in the cell cycle upon differentiation. This is in contrast to normal cells, which lose proliferative capability ...

journal_title：Journal of virology

authors： Melar-New M,Laimins LA

更新日期：2010-05-01 00:00:00

abstract：:The family of giant viruses is still expanding, and evidence of a translational machinery is emerging in the virosphere. The Klosneuvirinae group of giant viruses was first reconstructed from in silico studies, and then a unique member was isolated, Bodo saltans virus. Here we describe the isolation of a new member in...

journal_title：Journal of virology

authors： Bajrai LH,Mougari S,Andreani J,Baptiste E,Delerce J,Raoult D,Azhar EI,La Scola B,Levasseur A

更新日期：2019-12-12 00:00:00

abstract：:We established a novel experimental model for human T-cell leukemia virus type 1 (HTLV-1)-induced tumor using NOD-SCID/gammac(null) (NOG) mice. This model is very useful for investigating the mechanism of tumorigenesis and malignant cell growth of adult T-cell leukemia (ATL)/lymphoma, which still remains unclear. Nine...

journal_title：Journal of virology

authors： Dewan MZ,Terashima K,Taruishi M,Hasegawa H,Ito M,Tanaka Y,Mori N,Sata T,Koyanagi Y,Maeda M,Kubuki Y,Okayama A,Fujii M,Yamamoto N

更新日期：2003-05-01 00:00:00

abstract：:Epithelial cells lining mucosal surfaces impose multiple barriers to viral infection. At the ocular surface, the carbohydrate-binding protein galectin-3 maintains barrier function by cross-linking transmembrane mucins on the apical glycocalyx. Despite these defense mechanisms, many viruses have evolved to exploit fund...

journal_title：Journal of virology

authors： Woodward AM,Mauris J,Argüeso P

更新日期：2013-05-01 00:00:00

abstract：:Production of human papillomavirus type 16 (HPV-16) virus particles is totally dependent on the differentiation-dependent induction of viral L1 and L2 late gene expression. The early polyadenylation signal in HPV-16 plays a major role in the switch from the early to the late, productive stage of the viral life cycle. ...

journal_title：Journal of virology

authors： Oberg D,Fay J,Lambkin H,Schwartz S

更新日期：2005-07-01 00:00:00

abstract：:Vaccinia extracellular enveloped virus (EEV) is critical for cell-to-cell and long-range virus spread both in vitro and in vivo. The B5R gene encodes an EEV-specific type I membrane protein that is essential for efficient EEV formation. The majority of the B5R ectodomain consists of four domains with homology to short...

journal_title：Journal of virology

authors： Aldaz-Carroll L,Whitbeck JC,Ponce de Leon M,Lou H,Hirao L,Isaacs SN,Moss B,Eisenberg RJ,Cohen GH

更新日期：2005-05-01 00:00:00

abstract：:Many complex viruses use an assembly pathway in which their genome is packaged into an empty procapsid which subsequently matures into its final expanded form. We utilized Pseudomonas phage 6, a well-established virus assembly model, to probe the plasticity of the procapsid maturation pathway. The 6 packaging nucleosi...

journal_title：Journal of virology

authors： Sun X,Pirttimaa MJ,Bamford DH,Poranen MM

更新日期：2013-12-01 00:00:00

abstract：:Some of the properties of a new human papovavirus, BK, have been examined. Host range studies of BK virus (BKV) showed human cells to be more sensitive to infection than monkey cells; human fetal brain cells appear to be highly sensitive to BKV, with the production of extensive cytopathology characterized by cytoplasm...

journal_title：Journal of virology

authors： Takemoto KK,Mullarkey MF

更新日期：1973-09-01 00:00:00

abstract：:Treatment with sodium dodecyl sulfate (SDS) converted the vaccinia virus strain IHD-J into particles of two types: (i) ghosts which possessed a thin-membrane vesicle derived from basement part of the virus membrane with attached lateral bodies and a membranous structure derived from the core wall and (ii) aggregates o...

journal_title：Journal of virology

authors： Ichihashi Y,Oie M,Tsuruhara T

更新日期：1984-06-01 00:00:00

abstract：:The Kaposi's sarcoma-associated herpesvirus (KSHV) (or human herpesvirus 8) open reading frame (ORF) K15 encodes a putative integral transmembrane protein in the same genomic location as latent membrane protein 2A of Epstein-Barr virus. Ectopic expression of K15 in cell lines revealed the presence of several different...

journal_title：Journal of virology

authors： Sharp TV,Wang HW,Koumi A,Hollyman D,Endo Y,Ye H,Du MQ,Boshoff C

更新日期：2002-01-01 00:00:00

abstract：:The temperature-sensitive defects of virus mutants isolated from L cells persistently infected with Newcastle disease virus (NDV) were analyzed. Genetic grouping of the mutants by complementation tests was attempted by using several different methods, including yield analysis, RNA synthesis, and heterozygote formation...

journal_title：Journal of virology

authors： Preble OT,Youngner JS

更新日期：1973-09-01 00:00:00

abstract：:Adenovirus (Ad) gene transfer vectors can be used to transfer and express antigens and function as strong adjuvants and thus are useful platforms for the development of genetic vaccines. Based on the hypothesis that Ad vectors with enhanced infectibility of dendritic cells (DC) may be able to evoke enhanced immune res...

journal_title：Journal of virology

authors： Worgall S,Busch A,Rivara M,Bonnyay D,Leopold PL,Merritt R,Hackett NR,Rovelink PW,Bruder JT,Wickham TJ,Kovesdi I,Crystal RG

更新日期：2004-03-01 00:00:00

abstract：:Based on previous structural and functional studies, a potential receptor-binding site composed of residues that form a pocket at one end of the two long antiparallel helices in the receptor-binding domain of Friend 57 murine leukemia virus envelope protein (RBD) has been proposed. To test this hypothesis, directed su...

journal_title：Journal of virology

authors： Davey RA,Zuo Y,Cunningham JM

更新日期：1999-05-01 00:00:00

abstract：:The alphaherpesvirus proteins UL31 and UL34 and their homologues in other herpesvirus subfamilies cooperate at the nuclear membrane in the export of nascent herpesvirus capsids. We studied the respective betaherpesvirus proteins M53 and M50 in mouse cytomegalovirus (MCMV). Recently, we established a random approach to...

journal_title：Journal of virology

authors： Popa M,Ruzsics Z,Lötzerich M,Dölken L,Buser C,Walther P,Koszinowski UH

更新日期：2010-09-01 00:00:00

abstract：:As potential targets for human immunodeficiency virus type 1 and simian immunodeficiency virus (HIV-1 and SIV), dendritic cells (DCs) likely play a significant role in the onset and spread of infection as well as in the induction of antiviral immunity. Using the SIV-macaque system to study the very early events in DC-...

journal_title：Journal of virology

authors： Frank I,Piatak M Jr,Stoessel H,Romani N,Bonnyay D,Lifson JD,Pope M

更新日期：2002-03-01 00:00:00

abstract：:Rift Valley fever virus strain MP-12 was generated by serial plaque passages of parental strain ZH548 12 times in MRC-5 cells in the presence of a chemical mutagen, 5-fluorouracil. As a result, MP-12 encoded 4, 9, and 10 mutations in the S, M, and L segments, respectively. Among them, mutations in the M and L segments...

journal_title：Journal of virology

authors： Lokugamage N,Freiberg AN,Morrill JC,Ikegami T

更新日期：2012-12-01 00:00:00

abstract：UNLABELLED:Marek's disease virus (MDV), an alphaherpesvirus, is the causative agent of a lethal disease in chickens characterized by generalized nerve inflammation and rapid lymphoma development. The extensive colinearity of the MDV genome with those of related herpesviruses has eased functional characterization of man...

journal_title：Journal of virology

authors： Schippers T,Jarosinski K,Osterrieder N

更新日期：2015-01-15 00:00:00

abstract：:Live-attenuated vesicular stomatitis virus (VSV) vectors expressing foreign antigens induce potent immune responses and protect against viral diseases in animal models. Highly attenuated (VSV-CT1) or single-cycle VSV (VSVDeltaG) vectors induce immune responses lower than those generated by attenuated wild-type VSV vec...

journal_title：Journal of virology

authors： Simon ID,Publicover J,Rose JK

更新日期：2007-02-01 00:00:00