Etiology of leukaemias, with special reference to genetic problems.

Abstract:

:A critical review is made of the present knowledge of the etiology of neoplasms of the haematopoietic system in experimental animals and man. Genetic factors play a dominant role in the origin of leukaemias in mice. A Mendelian interpretation of the data is excluded and several genes appear to be involved in susceptibility. The data available on leukaemias in man are equivocal so far as the role of genetic factors is involved. The author discusses the value of family and twin studies-which suggest the operation of rare, highly penetrant, recessive genes-and of cytogenetic studies in contributing to a fuller understanding of the nature and etiology of leukaemia.

authors

LAW LW

subject

Has Abstract

pub_date

1962-01-01 00:00:00

pages

607-12

eissn

0042-9686

issn

1564-0604

journal_volume

26

pub_type

杂志文章
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    abstract::This Memorandum discusses two areas of research into rheumatic disease in which it is considered international cooperation would be valuable. These are: (a) standardization and cooperative evaluation of immunological tests used in diagnosis, clinico-pathological assessment, and epidemiological work; and (b) standardiz...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1974-01-01 00:00:00

  • International standard for hyaluronidase.

    abstract::The International Standard for Hyaluronidase is derived from a blend of four batches of bovine testicular hyaluronidase which had been purified so as to contain approximately 400 units per milligram. The material was mixed with beta-lactose, and lyophilized. Tablets were made from the dried mixture, and were examined ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: HUMPHREY JH

    更新日期:1957-01-01 00:00:00

  • Staphylococcal carriage in man. An attempt at a quantitative survey.

    abstract::The author reviews the published findings on the carriage of Staphylococcus pyogenes var. aureus during the last two decades, dealing mainly with observations made in British Commonwealth countries, Scandinavia and the USA. The importance of the role played by staphylococcal carriers in the spread of infection both in...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: MUNCH-PETERSEN E

    更新日期:1961-01-01 00:00:00

  • Trends in caesarean delivery by country and wealth quintile: cross-sectional surveys in southern Asia and sub-Saharan Africa.

    abstract:OBJECTIVE:To examine temporal trends in caesarean delivery rates in southern Asia and sub-Saharan Africa, by country and wealth quintile. METHODS:Cross-sectional data were extracted from the results of 80 Demographic and Health Surveys conducted in 26 countries in southern Asia or sub-Saharan Africa. Caesarean deliver...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/BLT.13.117598

    authors: Cavallaro FL,Cresswell JA,França GV,Victora CG,Barros AJ,Ronsmans C

    更新日期:2013-12-01 00:00:00

  • Children with hearing impairment in Malawi, a cohort study.

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    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/BLT.18.226241

    authors: Mulwafu W,Tataryn M,Polack S,Viste A,Goplen FK,Kuper H

    更新日期:2019-10-01 00:00:00

  • The pricing and procurement of antiretroviral drugs: an observational study of data from the Global Fund.

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    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/blt.05.025684

    authors: Vasan A,Hoos D,Mukherjee JS,Farmer PE,Rosenfield AG,Perriëns JH

    更新日期:2006-05-01 00:00:00

  • A 5-year study of patients with pulmonary tuberculosis in a concurrent comparison of home and sanatorium treatment for one year with isoniazid plus PAS.

    abstract::This report from the Tuberculosis Chemotherapy Centre, Madras, summarizes the progress over a 5-year period of 193 patients with newly diagnosed, sputum-positive pulmonary tuberculosis who were admitted to a concurrent comparison of home and sanatorium treatment for one year with isoniazid plus PAS. Previous reports h...

    journal_title:Bulletin of the World Health Organization

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Dawson JJ,Devadatta S,Fox W,Radhakrishna S,Ramakrishnan CV,Somasundaram PR,Stott H,Tripathy SP,Velu S

    更新日期:1966-01-01 00:00:00

  • Peri-operative pulse oximetry in low-income countries: a cost-effectiveness analysis.

    abstract:OBJECTIVE:To evaluate the cost-effectiveness of pulse oximetry--compared with no peri-operative monitoring--during surgery in low-income countries. METHODS:We considered the use of tabletop and portable, hand-held pulse oximeters among patients of any age undergoing major surgery in low-income countries. From earlier ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,评审

    doi:10.2471/BLT.14.137315

    authors: Burn SL,Chilton PJ,Gawande AA,Lilford RJ

    更新日期:2014-12-01 00:00:00

  • The alpha antitoxin content of the international reference preparations of Clostridium welchii types B and D antitoxins.

    abstract::The alpha antitoxin contents of the International Reference Preparations of Clostridium welchii Types B and D Antitoxins were assayed against two type A test toxins-Cl. welchii (perfringens) test toxin P2, issued by the Statens Seruminstitut, Copenhagen, and Cl. welchii test toxin AGX 1373, issued by the Wellcome Rese...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: SKULBERG A,VAN HEYNINGEN WE

    更新日期:1956-01-01 00:00:00

  • Standard management of acute respiratory infections in a children's hospital in Pakistan: impact on antibiotic use and case fatality.

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    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Qazi SA,Rehman GN,Khan MA

    更新日期:1996-01-01 00:00:00

  • A VILLAGE-SCALE TRIAL WITH DICHLORVOS AS A RESIDUAL FUMIGANT INSECTICIDE IN SOUTHERN NIGERIA.

    abstract::Hut and village-scale trials with solid and liquid-type dichlorvos dispensers were carried out in 1961 in the vicinity of Lagos, Nigeria, by the WHO Insecticide Testing Unit. Bioassay results indicated that with a single application satisfactory mortalities of caged mosquitos could be obtained for a period of 12-13 we...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: GRATZ NG,BRACHA P,CARMICHAEL A

    更新日期:1963-01-01 00:00:00

  • Primary health screening by haemoglobinometry in a tropical community.

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    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Johns WL,Lewis SM

    更新日期:1989-01-01 00:00:00

  • [A method for field detection of adult-mosquito resistance to DDT residues].

    abstract::A test procedure involving simply-constructed, portable test-equipment has been developed for detecting resistance to DDT residual applications by adult mosquitos. The procedure involves timed exposures of adult female mosquitos to DDT residues in chambers made of paper and screen wire, and the determination of the su...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: FAY RW,KILPATRIK JW,CROWELL RL,QUARTERMAN KD

    更新日期:1953-01-01 00:00:00

  • Reliability of clinical diagnosis in identifying infectious trachoma in a low-prevalence area of Nepal.

    abstract::The WHO Alliance for Global Elimination of Trachoma by 2020 has increased the need to identify ocular chlamydial infections by clinical examination in areas of both high and low prevalence. The relationship between clinically active trachoma (as defined by clinical examination) and chlamydial infection is known for ar...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Baral K,Osaki S,Shreshta B,Panta CR,Boulter A,Pang F,Cevallos V,Schachter J,Lietman T

    更新日期:1999-01-01 00:00:00

  • Paula Radcliffe: elite athlete and clean air advocate.

    abstract::Paula Radcliffe tells Gary Humphreys about her journey from athlete to clean air advocate and her hopes for a clean air initiative launched by the International Association of Athletics Federation. ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 面试,新闻

    doi:10.2471/BLT.19.030319

    authors:

    更新日期:2019-03-01 00:00:00

  • Method for the classification of countries according to health-related indicators.

    abstract::A taxonomic approach using cluster analysis and principal component analysis has grouped the countries of the world in eight clusters, in an initial attempt to propose a worldwide spatial classification based on the following health-related indicators: (a) those directly related to the health status of the population;...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Verhasselt Y,Mansourian B

    更新日期:1989-01-01 00:00:00

  • The psychiatric aspects of tropical disorders.

    abstract::The nature of psychiatric disorders in tropical regions is affected much more by the effect on the patient of certain environmental and cultural factors than by any specific features of tropical diseases. In places where the standards of health care and health education are not yet fully developed, abnormalities of ph...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: German GA

    更新日期:1979-01-01 00:00:00

  • A survey of antibodies to Adenovirus 8 and Coxsackievirus A21 in human sera.

    abstract::Studies have recently been published of surveys of antibodies to common respiratory viruses in human sera from several parts of the world. The present article reports the findings of a survey of antibodies to two more viruses (adenovirus type 8 and coxsackievirus type A21) in human sera mainly collected from six widel...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Chapple PJ

    更新日期:1966-01-01 00:00:00

  • Survey of BCG vaccination policy in Europe: 1994-96.

    abstract::A retrospective survey, based on a standardized questionnaire sent to qualified public health experts in tuberculosis in 50 European countries, was carried out to evaluate the following: concordance between national vaccination programmes and WHO recommendations on BCG vaccination for prevention of tuberculosis; relat...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Trnka L,Dankova D,Zitova J,Cimprichova L,Migliori GB,Clancy L,Zellweger JP

    更新日期:1998-01-01 00:00:00

  • Diluents for stabilization of tuberculin.

    abstract::Tuberculin is known to be adsorbed to containers and syringes. In the present paper, the adsorption which takes place in the ampoules has been studied in relation to the diluent for the tuberculin.Adsorption was most evident in dilutions prepared with saline or with phosphate buffer containing dextran. The inclusion i...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: MAGNUSSON M,GULD J,MAGNUS K,WAALER H

    更新日期:1958-01-01 00:00:00

  • Resurgence of Anopheles sacharovi following malaria eradication.

    abstract::In the Lamia Plain, Greece, 12 years after the cessation of DDT spraying, Anopheles sacharovi is still present in very high densities and appears to have the same biting habits and host preferences as previously. Mosquitos of this species are still resistant to DDT and dieldrin. ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Hadjinicolaou J,Betzios B

    更新日期:1973-06-01 00:00:00

  • Collaboration is key for new global tuberculosis strategy.

    abstract::This month the World Health Assembly discusses the post-2015 global tuberculosis strategy and accompanying set of targets. Giovanni Battista Migliori tells Fiona Fleck how his institute - one of WHO's thousands of partners across the globe - can contribute in future to its implementation, once it is approved. ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 面试,新闻

    doi:10.2471/BLT.14.030514

    authors: Migliori GB,Fleck F

    更新日期:2014-05-01 00:00:00

  • The burden of road traffic crashes, injuries and deaths in Africa: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To estimate the burden of road traffic injuries and deaths for all road users and among different road user groups in Africa. METHODS:We searched MEDLINE, EMBASE, Global Health, Google Scholar, websites of African road safety agencies and organizations for registry- and population-based studies and reports o...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,meta分析,评审

    doi:10.2471/BLT.15.163121

    authors: Adeloye D,Thompson JY,Akanbi MA,Azuh D,Samuel V,Omoregbe N,Ayo CK

    更新日期:2016-07-01 00:00:00

  • Organizational methods used in an epidemiological study in Leningrad.

    abstract::This paper describes the organization of an epidemiological survey, carried out by the Lipid Centre of the Institute of Experimental Medicine in Leningrad, particularly the ways in which subjects were recruited. The different methods of recruitment resulted in a total population response of 78.14%. A time index is int...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Katrusenko AG,Sestov DB

    更新日期:1981-01-01 00:00:00

  • Plasmodium falciparum in Haiti: susceptibility to pyrimethamine and sulfadoxine-pyrimethamine.

    abstract::Eighteen patients with Plasmodium falciparum infection were studied in Port-au-Prince, Haiti, to monitor the response of the malaria parasite to sulfadoxine-pyrimethamine. In all infections the parasitaemia was cleared rapidly following treatment with standard dose of the drug combination; no recrudescence was observe...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Nguyen-Dinh P,Zevallos-Ipenza A,Magloire R

    更新日期:1984-01-01 00:00:00

  • The cost of type 1 diabetes: a nationwide multicentre study in Brazil.

    abstract:OBJECTIVE:To determine the direct medical costs of type 1 diabetes mellitus (T1DM) to the National Brazilian Health-Care System (NBHCS) and quantify the contribution of each individual component to the total cost. METHODS:A retrospective, cross-sectional, nationwide multicentre study was conducted between 2008 and 201...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,多中心研究

    doi:10.2471/BLT.12.110387

    authors: Cobas RA,Ferraz MB,Matheus AS,Tannus LR,Negrato CA,Antonio de Araujo L,Dib SA,Gomes MB,Brazilian Type 1 Diabetes Study Group.

    更新日期:2013-06-01 00:00:00

  • Agricultural pesticide exposure and perinatal mortality in central Sudan.

    abstract::Hospital- and community-based studies were conducted in central Sudan to investigate the association between pesticide exposure and perinatal mortality. The cases were 197 stillbirths in the hospital and 36 perinatal deaths in the community; the controls were 812 liveborn, normal-birth-weight infants in the hospital, ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Taha TE,Gray RH

    更新日期:1993-01-01 00:00:00

  • Vitamin A supplementation for refugees and famine victims.

    abstract::Reports about recent famine victims and refugees have described the occurrence of xerophthalmia and resultant blindness related to severe vitamin A deficiency. These populations are subject to high prevalences of childhood protein-energy malnutrition and infectious diseases, pre-existing marginal vitamin A status, and...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Nieburg P,Waldman RJ,Leavell R,Sommer A,DeMaeyer EM

    更新日期:1988-01-01 00:00:00

  • A programme to improve quality of care for patients with chronic diseases, Kazakhstan.

    abstract:Objective:To evaluate the effect of a disease management programme in Kazakhstan on quality indicators for patients with hypertension, diabetes and chronic heart failure. Methods:A supportive, interdisciplinary, quality improvement programme was implemented between November 2014 and November 2015 at seven polyclinics ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/BLT.18.227447

    authors: Chan BT,Rauscher C,Issina AM,Kozhageldiyeva LH,Kuzembaeva DD,Davis CL,Kravchenko H,Hindmarsh M,McGowan J,Kulkaeva G

    更新日期:2020-03-01 00:00:00

  • Laboratory diagnosis of trachoma: a collaborative study.

    abstract::A collaborative study on the laboratory diagnosis of trachoma was carried out in three laboratories. A standardized complement fixation (CF) test with chlamydial (bedsonial) group antigen was found to be highly reproducible. The results obtained by different laboratories using the method and reagents suggested by the ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Schachter J,Mordhorst CH,Moore BW,Tarizzo ML

    更新日期:1973-05-01 00:00:00