Abstract：
:The Purchase price report released in August 2004 by the Global Fund to Fight AIDS, Tuberculosis, and Malaria (Global Fund) was the first publication of a significant amount of real transaction purchase data for antiretrovirals (ARVs). We did an observational study of the ARV transaction data in the Purchase price report to examine the procurement behaviour of principal recipients of Global Fund grants in developing countries. We found that, with a few exceptions for specific products (e.g. lamivudine) and regions (e.g. eastern Europe), prices in low-income countries were broadly consistent or lower than the lowest differential prices quoted by the research and development sector of the pharmaceutical industry. In lower middle-income countries, prices were more varied and in several instances (lopinavir/ritonavir, didanosine, and zidovudine/lamivudine) were very high compared with the per capita income of the country. In all low- and lower middle-income countries, ARV prices were still significantly high given limited local purchasing power and economic strength, thus reaffirming the need for donor support to achieve rapid scale-up of antiretroviral therapy. However, the price of ARVs will have to decrease to render scale-up financially sustainable for donors and eventually for governments themselves. An important first step in reducing prices will be to make available in the public domain as much ARV transaction data as possible to provide a factual basis for discussions on pricing. The price of ARVs has considerable implications for the sustainability of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) treatment in the developing world.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Vasan A,Hoos D,Mukherjee JS,Farmer PE,Rosenfield AG,Perriëns JHdoi
10.2471/blt.05.025684subject
Has Abstractpub_date
2006-05-01 00:00:00pages
393-8issue
5eissn
0042-9686issn
1564-0604pii
S0042-96862006000500020journal_volume
84pub_type
杂志文章abstract：:User fees are used to recover costs and discourage unnecessary attendance at primary care clinics in many developing countries. In South Africa, user fees for children aged under 6 years and pregnant women were removed in 1994, and in 1997 all user fees at all primary health care clinics were abolished. The intention ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The frequency of man-biting by mosquitos depends upon the amount of contact between man and mosquito, which in turn depends upon the behaviour patterns of both. In order to examine these relationships in an area with a high incidence of malaria, a study was made in 1965 of the nocturnal movements and of mosquito bitin...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1968-01-01 00:00:00
abstract：:Marion Koopmans tells Fiona Fleck why the world needs a publicly-funded network of hubs in all regions with local experts able to respond to infectious disease threats as they emerge. ...
journal_title：Bulletin of the World Health Organization
pub_type： 传,历史文章,新闻
doi：10.2471/BLT.18.030218
更新日期：2018-02-01 00:00:00
abstract：Objective:To determine the prevalence of and factors associated with dispensing antibiotics without a prescription in online and community pharmacies in China. Methods:We conducted a nationwide cross-sectional study of online and community pharmacies in 27 cities and counties in nine provinces in China (selected by mu...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.19.242370
更新日期：2020-07-01 00:00:00
abstract：:Few experiments have been reported on immunity to reinfection in domestic stock. The degree of resistance to reinfection with S. mattheei was studied in cattle and sheep. On the basis of the results, the only evidence of acquired immunity in calves and sheep is a reduction in the length of adult worms. ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1974-01-01 00:00:00
abstract：OBJECTIVE:To determine trends in mortality from respiratory disease in several areas of Latin America between 1998 and 2009. METHODS:The numbers of deaths attributed to respiratory disease between 1998 and 2009 were extracted from mortality data from Argentina, southern Brazil, Chile, Costa Rica, Ecuador, Mexico and P...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.12.116871
更新日期：2013-07-01 00:00:00
abstract：:In the course of an investigation in 1962-64 into the natural occurrence of brucellosis among grey foxes in Argentina, agglutination tests were performed on 728 sera of the foxes Dusicyon gymnocercus antiquus and D. griseus griseus, captured in the provinces of Buenos Aires and Rio Negro. Agglutination titres of from ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1966-01-01 00:00:00
abstract：:The lack of a simple and reliable test for sulfonamides has created a problem because of the increasing use of these drugs in the chemotherapy of malaria. This paper describes a modification of the Bratton-Marshall technique, for which the reagents are easily obtainable and which can be carried out in simply equipped ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:The WHO Bilharziasis Advisory Team made a survey in Upper Volta during May and June 1960. Data available indicate that S. haematobium is widely scattered throughout the country and that about 50% of the population, or more than 1.5 million people, are infected at some time during their lives. The examination of faeces...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1962-01-01 00:00:00
abstract：Objective:To estimate the use of hospitals for four essential primary care services offered in health centres in low- and middle-income countries and to explore differences in quality between hospitals and health centres. Methods:We extracted data from all demographic and health surveys conducted since 2010 on the typ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.19.245563
更新日期：2020-11-01 00:00:00
abstract：:Malathion shows promise as a substitute for chlorinated-hydrocarbon insecticides in the control of malaria whenever the latter are unsuitable because of Anopheles resistance or other reasons. A field trial of malathion was carried out in 1963-64, covering an area of about 500 km(2) with a population of about 26 000, i...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1967-01-01 00:00:00
abstract：:This is a classification of tumours of fibrous tissue, fat, muscle, blood and lymph vessels, and mast cells, irrespective of the region of the body in which they arise. Tumours of fibrous tissue are divided into fibroma, fibrosarcoma (including "canine haemangiopericytoma"), other sarcomas, equine sarcoid, and various...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1974-01-01 00:00:00
abstract：:Each of 87 strains of brucellae examined for its utilization of amino acid and carbohydrate substrates displayed a metabolic pattern that characterized it as to its species identity, irrespective of its serological and biochemical characters. Strains that displayed the metabolic pattern of Br. abortus were lysed by Br...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1962-01-01 00:00:00
abstract：:The antigenic structure of eight strains of influenza A viruses of avian origin was investigated by haemagglutination inhibition, virus neutralization and strain-specific complement fixation. All strains could be distinguished from each other, but certain cross-reactions were observed allowing the establishment of fou...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1965-01-01 00:00:00
abstract：:The age-adjusted incidence rate of cervical cancer in Bombay has decreased over the last 20 years, whereas over the same period that of breast cancer increased slightly. Studies indicate that the incidence of cervical cancer is lower in successively later-born cohorts, but no cohort effect has been observed for breast...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1986-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the screening measures that would have been required to assess all travellers at risk of transporting A(H1N1)pdm09 out of Mexico by air at the start of the 2009 pandemic. METHODS:Data from flight itineraries for travellers who flew from Mexico were used to estimate the number of international air...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.12.114777
更新日期：2013-05-01 00:00:00
abstract：:Malarial antibody levels were measured by the enzyme-linked immunosorbent assay (ELISA) in two West African populations, one exposed to intense malaria transmission and the other protected. The results reflected the transmission of maternal antibody and, in the unprotected population, the subsequent increase of the EL...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
abstract：:Malaria parasites in mice present a simplified rodent model for the immunological study of malaria. Experiments have been performed to determine the pattern and persistence of malaria antibody as detected by the indirect fluorescent antibody (IFA) test utilizing specific antimouse IgM and IgG conjugates. The antibody ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1974-01-01 00:00:00
abstract：OBJECTIVES:Most data on self-poisoning in rural Asia have come from secondary hospitals. We aimed to: assess how transfers from primary to secondary hospitals affected estimates of case-fatality ratio (CFR); determine whether there was referral bias according to gender or poison; and estimate the annual incidence of al...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.05.025379
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To improve the use and dosage of antibiotics prescribed at Commune Health Stations in Viet Nam, and in so doing find out whether antibiotic dosage can be easily and reliably measured as a drug-use indicator. METHODS:All commune health workers from the 217 commune health stations in Hai Phong Province, Viet N...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：:The use of BCG vaccine in the prevention of leprosy has been one of the most important subjects of investigation in the field of leprology in the last 25 years. The action of the vaccine was for many years investigated by determining its effect on the lepromin reaction. Field studies were later considered essential to...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1970-01-01 00:00:00
abstract：:Haematological surveys of adult population samples were conducted simultaneously in 12 countries, all but one of which are in Europe. Haematological estimations on samples from nine of the countries were made in one central laboratory. Differences between countries in the mean levels of haemoglobin (and haematocrit an...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：OBJECTIVE:To examine the association between maternal smoking and non-syndromic orofacial clefts in infants. METHODS:A meta-analysis of the association between maternal smoking during pregnancy was carried out using data from 24 case-control and cohort studies. FINDINGS:Consistent, moderate and statistically signific...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,meta分析
doi：
更新日期：2004-03-01 00:00:00
abstract：:As a basis for considering the forms and patterns of national committees on vital and health statistics in the future, the author first discusses the six main objectives of national systems of those statistics. Turning then to the aims of the national committees themselves, he observes that such is the variety of stat...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1954-01-01 00:00:00
abstract：OBJECTIVE:To investigate, in Amhara, Ethiopia, the association between prevalence of active trachoma among children aged 1-9 years and community sanitation usage. METHODS:Between 2011 and 2014, prevalence of trachoma and household pit latrine usage were measured in five population-based cross-sectional surveys. Data o...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.16.177758
更新日期：2017-04-01 00:00:00
abstract：:Poxviruses were isolated from the kidneys of an outwardly healthy chimpanzee trapped in an area of the Democratic Republic of the Congo where a case of monkeypox had recently occurred in man, from the kidneys of clinically healthy cynomolgus monkeys in a colony in the Netherlands, and from monkeys suffering from monke...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：OBJECTIVE:To determine the extent to which the community-directed approach used in onchocerciasis control in Africa could effectively and efficiently provide integrated delivery of other health interventions. METHODS:A three-year experimental study was undertaken in 35 health districts from 2005 to 2007 in seven resea...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.2471/BLT.09.069203
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:To measure the socioeconomic inequality in infant mortality in Iran (the Islamic Republic of Iran). METHODS:We analysed data from the provincially representative Demographic and Health Survey, which was done in Iran in 2000. We used a dichotomous hierarchical ordered probit model to develop an indicator of s...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：/S0042-96862005001100013
更新日期：2005-11-01 00:00:00
abstract：:The author reviews the published findings on the carriage of Staphylococcus pyogenes var. aureus during the last two decades, dealing mainly with observations made in British Commonwealth countries, Scandinavia and the USA. The importance of the role played by staphylococcal carriers in the spread of infection both in...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1961-01-01 00:00:00
abstract：:Termination of early pregnancy by vacuum aspiration is a well-established technique. The procedure is highly effective and has a low complication rate, particularly when performed during the first few weeks after missed menses. However, this parasurgical method requires skilled health care personnel, and attempts have...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1989-01-01 00:00:00
