The alpha antitoxin content of the international reference preparations of Clostridium welchii types B and D antitoxins.

Abstract:

:The alpha antitoxin contents of the International Reference Preparations of Clostridium welchii Types B and D Antitoxins were assayed against two type A test toxins-Cl. welchii (perfringens) test toxin P2, issued by the Statens Seruminstitut, Copenhagen, and Cl. welchii test toxin AGX 1373, issued by the Wellcome Research Laboratories, England-the alpha toxin contents of which were first determined against the International Standard Alpha Antitoxin. Three methods of assay were used: mouse killing (the L+ test); haemolysis of red blood cells (the Lh test); and production of turbidity in egg-yolk solution (the lecithinase or Lv test).Taking the mean of all tests, it was found that the International Reference Preparation of Cl. welchii Type B Antitoxin contained 282 units of alpha antitoxin per ml, while the International Reference Preparation of Cl. welchii Type D Antitoxin contained 93 units of alpha antitoxin per ml.

authors

SKULBERG A,VAN HEYNINGEN WE

subject

Has Abstract

pub_date

1956-01-01 00:00:00

pages

557-66

issue

3

eissn

0042-9686

issn

1564-0604

journal_volume

14

pub_type

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