International standard for hyaluronidase.

Abstract:

:The International Standard for Hyaluronidase is derived from a blend of four batches of bovine testicular hyaluronidase which had been purified so as to contain approximately 400 units per milligram. The material was mixed with beta-lactose, and lyophilized. Tablets were made from the dried mixture, and were examined extensively in the USA in order to establish their homogeneity and to relate their potency to the current USA "turbidity reducing unit" (TRU). On the basis of this examination, the International Unit for hyaluronidase is defined as the activity of 0.1 mg of the International Standard Preparation, and is very nearly equal to one TRU. It is recommended that the Standard be employed only for assaying testicular hyaluronidase, and that certain precautions be taken in its use.

authors

HUMPHREY JH

subject

Has Abstract

pub_date

1957-01-01 00:00:00

pages

291-4

issue

2

eissn

0042-9686

issn

1564-0604

journal_volume

16

pub_type

杂志文章
  • LIPOIDAL ANTIGEN AND TPI REACTIONS IN SERA FROM ETHIOPIA. EFFECT OF LONG-DISTANCE SERUM TRANSPORTATION ON ANTIBODIES.

    abstract::In order to evaluate results obtained in Addis Ababa with lipoidal antigen tests for syphilis on 269 human sera, and, if possible, to determine how many positive seroreactors were in fact infected with Treponema pallidum, these sera were sent by air to Copenhagen for re-examination by the VDRL, Kahn, CWRM and TPI test...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: SCHMIDT H

    更新日期:1964-01-01 00:00:00

  • Three basic convictions: a recipe for preventing child injuries.

    abstract::This paper represents a personal reflection on what is needed worldwide to prevent child injuries. It repeats messages that have been frequently delivered in the past. The main points are: first, the need for everyone to accept the view that, ultimately, injuries are a health problem and health departments must view t...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/blt.08.058024

    authors: Pless IB

    更新日期:2009-05-01 00:00:00

  • Field evaluation of the QBC technique for rapid diagnosis of vivax malaria.

    abstract::The QBC (quantitative buffy coat) technique was compared with that of the Giemsa-stained thick blood film (GTF) under field conditions in Junlian and Mingshan counties, Sichuan, China, for rapid diagnosis of vivax malaria. Blood samples were collected from 364 volunteer villagers, and each sample was examined with bot...

    journal_title:Bulletin of the World Health Organization

    pub_type: 临床试验,杂志文章

    doi:

    authors: Wang X,Zhu S,Liu Q,Hu A,Zan Z,Yu Q,Yin Q

    更新日期:1996-01-01 00:00:00

  • Chloroquine and desethylchloroquine concentrations during regular long-term malaria prophylaxis.

    abstract::The concentrations of chloroquine and desethylchloroquine in the blood of 10 healthy adult Swedish volunteers who had been taking 310 mg chloroquine base once a week for at least 8 months for malaria prophylaxis were measured. Samples of capillary whole blood from the volunteers were dried on filter-paper and the drug...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Rombo L,Bergqvist Y,Hellgren U

    更新日期:1987-01-01 00:00:00

  • Public health issues related to animal and human spongiform encephalopathies: memorandum from a WHO meeting.

    abstract::The transmissible spongiform encephalopathies (TSE) include bovine spongiform encephalopathy (BSE), which was first described in 1986 in the United Kingdom but has occurred subsequently in several other countries. This Memorandum reviews the existing state of knowledge on all the known spongiform encephalopathies, and...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,评审

    doi:

    authors:

    更新日期:1992-01-01 00:00:00

  • Serological diagnosis of HIV infection using oral fluid samples.

    abstract::The serological identification of antibodies to human immunodeficiency virus (HIV) in blood is the most widely used method to diagnose HIV infection. Recently, however, the use of oral fluid samples for the detection of antibodies to HIV has been suggested as an alternative. This review describes some basic informatio...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,评审

    doi:

    authors: Tamashiro H,Constantine NT

    更新日期:1994-01-01 00:00:00

  • Immunogenicity of purified, inactivated chikungunya virus in monkeys.

    abstract::Chikungunya (CHIK) virus, harvested from infected BHK-21 cell cultures and highly purified by a method combining zinc acetate precipitation, Sephadex-Sepharose column chromatography, and sucrose density gradient centrifugation, was subjected to ultraviolet (UV) irradiation and treatment with formalin. Inactivation of ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Nakao E,Hotta S

    更新日期:1973-05-01 00:00:00

  • Atherosclerosis of the aorta and coronary arteries in coronary heart disease.

    abstract::Aortic and coronary atherosclerosis and the prevalence of coronary stenosis and thrombosis were studied in subjects who had died of fresh or recurrent myocardial infarction or had suffered from myocardial infarction in the past. In general, severe atherosclerosis of the coronary arteries with stenosis and calcificatio...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Vihert AM

    更新日期:1976-01-01 00:00:00

  • Estimating the burden of shigellosis in Thailand: 36-month population-based surveillance study.

    abstract:OBJECTIVE:To estimate incidence of shigellosis in the Kaengkhoi district, Saraburi Province, Thailand. METHODS:Population-based surveillance of shigellosis based in treatment centres. The detected rates of treated shigellosis were corrected for the number of cases missed due to the low sensitivity of microbiological c...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:/S0042-96862005001000010

    authors: Chompook P,Samosornsuk S,von Seidlein L,Jitsanguansuk S,Sirima N,Sudjai S,Mangjit P,Kim DR,Wheeler JG,Todd J,Lee H,Ali M,Clemens J,Tapchaisri P,Chaicumpa W

    更新日期:2005-10-01 00:00:00

  • Childhood malaria in the Lao People's Democratic Republic.

    abstract::The idea that malaria in South-East Asia is synonymous with adult malaria is questioned in this paper. In the Lao People's Democratic Republic, community-based malariometric data were collected in Savannakhet Province, which shares borders with Viet Nam in the east and Thailand in the west. The data indicate that ende...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Anothay O,Pongvongsa T

    更新日期:1998-01-01 00:00:00

  • Treatment and prevention of kwashiorkor.

    abstract::Recent research carried out on kwashiorkor in Kampala, Uganda, is discussed. The first essential in both the treatment and the prevention of this disease being a diet rich in protein (preferably animal protein, to ensure an adequate intake of vitamin B(12) and a satisfactory mixture of amino-acids), methods of incorpo...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: DEAN RF

    更新日期:1953-01-01 00:00:00

  • Transport of amino acids and nucleic acid precursors in malarial parasites.

    abstract::In vitro studies have shown that exogenously supplied amino acids are transferred into the malaria-infected cell, where they are incorporated into proteins. Most amino acids appear to enter the cell by facilitated or simple diffusion; however, the high distribution ratios seen in Plasmodium knowlesi-infected cells are...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,评审

    doi:

    authors: Sherman IW

    更新日期:1977-01-01 00:00:00

  • Trends in mortality from respiratory disease in Latin America since 1998 and the impact of the 2009 influenza pandemic.

    abstract:OBJECTIVE:To determine trends in mortality from respiratory disease in several areas of Latin America between 1998 and 2009. METHODS:The numbers of deaths attributed to respiratory disease between 1998 and 2009 were extracted from mortality data from Argentina, southern Brazil, Chile, Costa Rica, Ecuador, Mexico and P...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/BLT.12.116871

    authors: de Souza Mde F,Widdowson MA,Alencar AP,Gawryszewski VP,Aziz-Baumgartner E,Palekar R,Breese J,Cheng PY,Barbosa J,Cabrera AM,Olea A,Flores AB,Shay DK,Mounts A,Oliva OP

    更新日期:2013-07-01 00:00:00

  • The arenaviruses: some priorities for future research.

    abstract::In this paper Lassa virus is used as a model in pinpointing priorities for future research on the arenaviruses. Suggestions for specific investigations and public health measures cover the detection of Lassa virus infection, the pathology and therapy of the disease, and its prevention and control. ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Johnson KM

    更新日期:1975-01-01 00:00:00

  • Community-directed interventions for priority health problems in Africa: results of a multicountry study.

    abstract:OBJECTIVE:To determine the extent to which the community-directed approach used in onchocerciasis control in Africa could effectively and efficiently provide integrated delivery of other health interventions. METHODS:A three-year experimental study was undertaken in 35 health districts from 2005 to 2007 in seven resea...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.2471/BLT.09.069203

    authors: CDI Study Group.

    更新日期:2010-07-01 00:00:00

  • The psychiatric aspects of tropical disorders.

    abstract::The nature of psychiatric disorders in tropical regions is affected much more by the effect on the patient of certain environmental and cultural factors than by any specific features of tropical diseases. In places where the standards of health care and health education are not yet fully developed, abnormalities of ph...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: German GA

    更新日期:1979-01-01 00:00:00

  • Idiopathic cardiomegaly.

    abstract::Cardiomyopathies are certain heart diseases of unknown etiology and pathogenesis, occurring mostly in tropical and subtropical areas, where they constitute a major clinical problem and sometimes a public health problem. The need for international co-operation in the study of such forms of heart disease has long been r...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1968-01-01 00:00:00

  • Coping with out-of-pocket health payments: empirical evidence from 15 African countries.

    abstract:OBJECTIVE:To explore factors associated with household coping behaviours in the face of health expenditures in 15 African countries and provide evidence for policy-makers in designing financial health protection mechanisms. METHODS:A series of logit regressions were performed to explore factors correlating with a grea...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/blt.07.049403

    authors: Leive A,Xu K

    更新日期:2008-11-01 00:00:00

  • Training of vector control personnel.

    abstract::Modern vector control campaigns cannot be conducted efficiently and economically unless the organization is staffed with personnel having a high standard of training. Both professional and non-professional personnel are employed at different levels in the organization and the type of training they require depends upon...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Shawarby AA

    更新日期:1963-01-01 00:00:00

  • Oral health manpower projection methods and their implications for developing countries: the case of Zimbabwe.

    abstract::Manpower projections for oral health are generally held to be more accurate than those for other health sectors since the diseases involved and their treatment times can be predicted more precisely. Nevertheless most oral health manpower projections are either overestimates or are not in line with the resources of ind...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Khan AA,Sithole WD

    更新日期:1991-01-01 00:00:00

  • Legal and institutional foundations for universal health coverage, Kenya.

    abstract::Kenya's Constitution of 2010 triggered a cascade of reforms across all sectors to align with new constitutional standards, including devolution and a comprehensive bill of rights. The constitution acts as a platform to advance health rights and to restructure policy, legal, institutional and regulatory frameworks towa...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/BLT.19.237297

    authors: Mbindyo R,Kioko J,Siyoi F,Cheruiyot S,Wangai M,Onsongo J,Omwoyo A,Kisia C,Miriti K

    更新日期:2020-10-01 00:00:00

  • New treatment gives hope to East Africa's drug users.

    abstract::The United Republic of Tanzania is the first mainland sub-Saharan country to launch a national methadone programme as part of its battle to fight the twin epidemics of heroin addiction and HIV infection. Fumbuka Ng'wanakilala reports. ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 新闻

    doi:10.2471/BLT.13.030213

    authors:

    更新日期:2013-02-01 00:00:00

  • Further studies on BCG vaccine prepared by tween 80 method with particular reference to effect of freeze-drying.

    abstract::The immunizing potency of liquid BCG vaccine prepared by the Tween 80 method was compared with that of control vaccine prepared by the usual grinding method. The former vaccine revealed higher immunizing properties than the latter although its inoculation dose was only one-fifth as great.With sodium glutamate as adjuv...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: TAKANO K,OBAYASHI Y,NOGUCHI T

    更新日期:1957-01-01 00:00:00

  • Rapid, low-cost, two-step method to screen for urinary schistosomiasis at the district level: the Kilosa experience.

    abstract::The operational and diagnostic performance of a two-step method for the cost-effective screening of urinary schistosomiasis was investigated in the Kilosa District of east-central Tanzania. In the first step a simple questionnaire was administered to 15,073 primary schoolchildren by their class teachers over a 4-week ...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Lengeler C,Kilima P,Mshinda H,Morona D,Hatz C,Tanner M

    更新日期:1991-01-01 00:00:00

  • [A method for field detection of adult-mosquito resistance to DDT residues].

    abstract::A test procedure involving simply-constructed, portable test-equipment has been developed for detecting resistance to DDT residual applications by adult mosquitos. The procedure involves timed exposures of adult female mosquitos to DDT residues in chambers made of paper and screen wire, and the determination of the su...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: FAY RW,KILPATRIK JW,CROWELL RL,QUARTERMAN KD

    更新日期:1953-01-01 00:00:00

  • Opt-out provider-initiated HIV testing and counselling in primary care outpatient clinics in Zambia.

    abstract:OBJECTIVE:To increase case-finding of infection with human immunodeficiency virus (HIV) in Zambia and their referral to HIV care and treatment by supplementing existing client-initiated voluntary counselling and testing (VCT), the dominant mode of HIV testing in the country. METHODS:Lay counsellors offered provider-in...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:10.2471/BLT.10.084442

    authors: Topp SM,Chipukuma JM,Chiko MM,Wamulume CS,Bolton-Moore C,Reid SE

    更新日期:2011-05-01 00:00:00

  • Recent outbreaks of lymphocytic choriomeningitis in the United States of America.

    abstract::Lymphocytic choriomeningitis (LCM) has been rarely reported in the American literature since 1960. It is interesting that each of the 3 epidemics reported since then has been associated with exposure to hamsters. In 1973, 48 cases of LCM spanning the years 1971-1973 occurred at the University of Rochester Medical Scho...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Gregg MB

    更新日期:1975-01-01 00:00:00

  • Control of a type 1 poliomyelitis epidemic in British Guiana, 1962-63, with trivalent oral poliovirus vaccine. 1. Epidemiological aspects.

    abstract::An epidemic of poliomyelitis took place in British Guiana during the winter of 1962-63. A total of 485 paralytic cases occurred over a 10-week period, 90% in children under 5 years of age.The attack rate for the total population of more than half-a-million persons was 86.5 per 100 000. Type 1 poliovirus was isolated f...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Witte JJ,Page MI,Gelfand HM

    更新日期:1965-01-01 00:00:00

  • Allergen nomenclature.

    abstract::This article presents a nomenclature system for allergens which has been officially recommended by the International Union of Immunological Societies (IUIS). The nomenclature is based on proposals of the IUIS Sub-Committee for Allergen Nomenclature and is applicable to highly purified, well-characterized allergens and...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章

    doi:

    authors: Marsh DG,Goodfriend L,King TP,Lowenstein H,Platts-Mills TA

    更新日期:1986-01-01 00:00:00

  • Inequities in postnatal care in low- and middle-income countries: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To assess the socioeconomic, geographical and demographic inequities in the use of postnatal health-care services in low- and middle-income countries. METHODS:We searched Medline, Embase and Cochrane Central databases and grey literature for experimental, quasi-experimental and observational studies that had...

    journal_title:Bulletin of the World Health Organization

    pub_type: 杂志文章,meta分析,评审

    doi:10.2471/BLT.14.140996

    authors: Langlois ÉV,Miszkurka M,Zunzunegui MV,Ghaffar A,Ziegler D,Karp I

    更新日期:2015-04-01 00:00:00