Abstract:
:The International Standard for Hyaluronidase is derived from a blend of four batches of bovine testicular hyaluronidase which had been purified so as to contain approximately 400 units per milligram. The material was mixed with beta-lactose, and lyophilized. Tablets were made from the dried mixture, and were examined extensively in the USA in order to establish their homogeneity and to relate their potency to the current USA "turbidity reducing unit" (TRU). On the basis of this examination, the International Unit for hyaluronidase is defined as the activity of 0.1 mg of the International Standard Preparation, and is very nearly equal to one TRU. It is recommended that the Standard be employed only for assaying testicular hyaluronidase, and that certain precautions be taken in its use.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
HUMPHREY JHsubject
Has Abstractpub_date
1957-01-01 00:00:00pages
291-4issue
2eissn
0042-9686issn
1564-0604journal_volume
16pub_type
杂志文章abstract::In order to evaluate results obtained in Addis Ababa with lipoidal antigen tests for syphilis on 269 human sera, and, if possible, to determine how many positive seroreactors were in fact infected with Treponema pallidum, these sera were sent by air to Copenhagen for re-examination by the VDRL, Kahn, CWRM and TPI test...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract::This paper represents a personal reflection on what is needed worldwide to prevent child injuries. It repeats messages that have been frequently delivered in the past. The main points are: first, the need for everyone to accept the view that, ultimately, injuries are a health problem and health departments must view t...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.08.058024
更新日期:2009-05-01 00:00:00
abstract::The QBC (quantitative buffy coat) technique was compared with that of the Giemsa-stained thick blood film (GTF) under field conditions in Junlian and Mingshan counties, Sichuan, China, for rapid diagnosis of vivax malaria. Blood samples were collected from 364 volunteer villagers, and each sample was examined with bot...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The concentrations of chloroquine and desethylchloroquine in the blood of 10 healthy adult Swedish volunteers who had been taking 310 mg chloroquine base once a week for at least 8 months for malaria prophylaxis were measured. Samples of capillary whole blood from the volunteers were dried on filter-paper and the drug...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::The transmissible spongiform encephalopathies (TSE) include bovine spongiform encephalopathy (BSE), which was first described in 1986 in the United Kingdom but has occurred subsequently in several other countries. This Memorandum reviews the existing state of knowledge on all the known spongiform encephalopathies, and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract::The serological identification of antibodies to human immunodeficiency virus (HIV) in blood is the most widely used method to diagnose HIV infection. Recently, however, the use of oral fluid samples for the detection of antibodies to HIV has been suggested as an alternative. This review describes some basic informatio...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::Chikungunya (CHIK) virus, harvested from infected BHK-21 cell cultures and highly purified by a method combining zinc acetate precipitation, Sephadex-Sepharose column chromatography, and sucrose density gradient centrifugation, was subjected to ultraviolet (UV) irradiation and treatment with formalin. Inactivation of ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-05-01 00:00:00
abstract::Aortic and coronary atherosclerosis and the prevalence of coronary stenosis and thrombosis were studied in subjects who had died of fresh or recurrent myocardial infarction or had suffered from myocardial infarction in the past. In general, severe atherosclerosis of the coronary arteries with stenosis and calcificatio...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract:OBJECTIVE:To estimate incidence of shigellosis in the Kaengkhoi district, Saraburi Province, Thailand. METHODS:Population-based surveillance of shigellosis based in treatment centres. The detected rates of treated shigellosis were corrected for the number of cases missed due to the low sensitivity of microbiological c...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:/S0042-96862005001000010
更新日期:2005-10-01 00:00:00
abstract::The idea that malaria in South-East Asia is synonymous with adult malaria is questioned in this paper. In the Lao People's Democratic Republic, community-based malariometric data were collected in Savannakhet Province, which shares borders with Viet Nam in the east and Thailand in the west. The data indicate that ende...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,多中心研究
doi:
更新日期:1998-01-01 00:00:00
abstract::Recent research carried out on kwashiorkor in Kampala, Uganda, is discussed. The first essential in both the treatment and the prevention of this disease being a diet rich in protein (preferably animal protein, to ensure an adequate intake of vitamin B(12) and a satisfactory mixture of amino-acids), methods of incorpo...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1953-01-01 00:00:00
abstract::In vitro studies have shown that exogenously supplied amino acids are transferred into the malaria-infected cell, where they are incorporated into proteins. Most amino acids appear to enter the cell by facilitated or simple diffusion; however, the high distribution ratios seen in Plasmodium knowlesi-infected cells are...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1977-01-01 00:00:00
abstract:OBJECTIVE:To determine trends in mortality from respiratory disease in several areas of Latin America between 1998 and 2009. METHODS:The numbers of deaths attributed to respiratory disease between 1998 and 2009 were extracted from mortality data from Argentina, southern Brazil, Chile, Costa Rica, Ecuador, Mexico and P...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.12.116871
更新日期:2013-07-01 00:00:00
abstract::In this paper Lassa virus is used as a model in pinpointing priorities for future research on the arenaviruses. Suggestions for specific investigations and public health measures cover the detection of Lassa virus infection, the pathology and therapy of the disease, and its prevention and control. ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:To determine the extent to which the community-directed approach used in onchocerciasis control in Africa could effectively and efficiently provide integrated delivery of other health interventions. METHODS:A three-year experimental study was undertaken in 35 health districts from 2005 to 2007 in seven resea...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.2471/BLT.09.069203
更新日期:2010-07-01 00:00:00
abstract::The nature of psychiatric disorders in tropical regions is affected much more by the effect on the patient of certain environmental and cultural factors than by any specific features of tropical diseases. In places where the standards of health care and health education are not yet fully developed, abnormalities of ph...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract::Cardiomyopathies are certain heart diseases of unknown etiology and pathogenesis, occurring mostly in tropical and subtropical areas, where they constitute a major clinical problem and sometimes a public health problem. The need for international co-operation in the study of such forms of heart disease has long been r...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract:OBJECTIVE:To explore factors associated with household coping behaviours in the face of health expenditures in 15 African countries and provide evidence for policy-makers in designing financial health protection mechanisms. METHODS:A series of logit regressions were performed to explore factors correlating with a grea...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.07.049403
更新日期:2008-11-01 00:00:00
abstract::Modern vector control campaigns cannot be conducted efficiently and economically unless the organization is staffed with personnel having a high standard of training. Both professional and non-professional personnel are employed at different levels in the organization and the type of training they require depends upon...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1963-01-01 00:00:00
abstract::Manpower projections for oral health are generally held to be more accurate than those for other health sectors since the diseases involved and their treatment times can be predicted more precisely. Nevertheless most oral health manpower projections are either overestimates or are not in line with the resources of ind...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::Kenya's Constitution of 2010 triggered a cascade of reforms across all sectors to align with new constitutional standards, including devolution and a comprehensive bill of rights. The constitution acts as a platform to advance health rights and to restructure policy, legal, institutional and regulatory frameworks towa...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.19.237297
更新日期:2020-10-01 00:00:00
abstract::The United Republic of Tanzania is the first mainland sub-Saharan country to launch a national methadone programme as part of its battle to fight the twin epidemics of heroin addiction and HIV infection. Fumbuka Ng'wanakilala reports. ...
journal_title:Bulletin of the World Health Organization
pub_type: 新闻
doi:10.2471/BLT.13.030213
更新日期:2013-02-01 00:00:00
abstract::The immunizing potency of liquid BCG vaccine prepared by the Tween 80 method was compared with that of control vaccine prepared by the usual grinding method. The former vaccine revealed higher immunizing properties than the latter although its inoculation dose was only one-fifth as great.With sodium glutamate as adjuv...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1957-01-01 00:00:00
abstract::The operational and diagnostic performance of a two-step method for the cost-effective screening of urinary schistosomiasis was investigated in the Kilosa District of east-central Tanzania. In the first step a simple questionnaire was administered to 15,073 primary schoolchildren by their class teachers over a 4-week ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract::A test procedure involving simply-constructed, portable test-equipment has been developed for detecting resistance to DDT residual applications by adult mosquitos. The procedure involves timed exposures of adult female mosquitos to DDT residues in chambers made of paper and screen wire, and the determination of the su...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1953-01-01 00:00:00
abstract:OBJECTIVE:To increase case-finding of infection with human immunodeficiency virus (HIV) in Zambia and their referral to HIV care and treatment by supplementing existing client-initiated voluntary counselling and testing (VCT), the dominant mode of HIV testing in the country. METHODS:Lay counsellors offered provider-in...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.10.084442
更新日期:2011-05-01 00:00:00
abstract::Lymphocytic choriomeningitis (LCM) has been rarely reported in the American literature since 1960. It is interesting that each of the 3 epidemics reported since then has been associated with exposure to hamsters. In 1973, 48 cases of LCM spanning the years 1971-1973 occurred at the University of Rochester Medical Scho...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::An epidemic of poliomyelitis took place in British Guiana during the winter of 1962-63. A total of 485 paralytic cases occurred over a 10-week period, 90% in children under 5 years of age.The attack rate for the total population of more than half-a-million persons was 86.5 per 100 000. Type 1 poliovirus was isolated f...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1965-01-01 00:00:00
abstract::This article presents a nomenclature system for allergens which has been officially recommended by the International Union of Immunological Societies (IUIS). The nomenclature is based on proposals of the IUIS Sub-Committee for Allergen Nomenclature and is applicable to highly purified, well-characterized allergens and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:To assess the socioeconomic, geographical and demographic inequities in the use of postnatal health-care services in low- and middle-income countries. METHODS:We searched Medline, Embase and Cochrane Central databases and grey literature for experimental, quasi-experimental and observational studies that had...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,meta分析,评审
doi:10.2471/BLT.14.140996
更新日期:2015-04-01 00:00:00