Comparison of the structures of three circoviruses: chicken anemia virus, porcine circovirus type 2, and beak and feather disease virus.

abstract：:Woodchuck hepatitis virus (WHV) mutants with core internal deletions (CID) occur naturally in chronically WHV-infected woodchucks, as do hepatitis B virus mutants in humans. We studied the replication of WHV deletion mutants in primary woodchuck hepatocyte cultures and in vivo after transmission to naive woodchucks. B...

journal_title：Journal of virology

authors： Lu M,Hilken G,Yang D,Kemper T,Roggendorf M

更新日期：2001-04-01 00:00:00

abstract：:Thanks to new technologies which enable rapid and unbiased screening for viral nucleic acids in clinical specimens, an impressive number of previously unknown viruses have recently been discovered. Two research groups independently identified a novel negative-strand RNA virus, now designated avian bornavirus (ABV), in...

journal_title：Journal of virology

authors： Staeheli P,Rinder M,Kaspers B

更新日期：2010-07-01 00:00:00

abstract：:Neurotropic herpesviruses depend on long-distance axon transport for the initial establishment of latency in peripheral ganglia (retrograde transport) and for viral spread in axons to exposed body surfaces following reactivation (anterograde transport). Images of neurons infected with herpes simplex virus type 1 (HSV-...

journal_title：Journal of virology

authors： Antinone SE,Zaichick SV,Smith GA

更新日期：2010-12-01 00:00:00

abstract：UNLABELLED:The measles virus (MeV) membrane fusion apparatus consists of a fusion protein trimer and an attachment protein tetramer. To trigger membrane fusion, the heads of the MeV attachment protein, hemagglutinin (H), bind cellular receptors while the 96-residue-long H stalk transmits the triggering signal. Structur...

journal_title：Journal of virology

authors： Navaratnarajah CK,Kumar S,Generous A,Apte-Sengupta S,Mateo M,Cattaneo R

更新日期：2014-06-01 00:00:00

abstract：:The aryl hydrocarbon receptor (AhR) is a cytoplasmic receptor/transcription factor that modulates several cellular and immunological processes following activation by pathogen-associated stimuli, though its role during virus infection is largely unknown. Here, we show that AhR is activated in cells infected with mouse...

journal_title：Journal of virology

authors： Grunewald ME,Shaban MG,Mackin SR,Fehr AR,Perlman S

更新日期：2020-01-17 00:00:00

abstract：:Based on previous structural and functional studies, a potential receptor-binding site composed of residues that form a pocket at one end of the two long antiparallel helices in the receptor-binding domain of Friend 57 murine leukemia virus envelope protein (RBD) has been proposed. To test this hypothesis, directed su...

journal_title：Journal of virology

authors： Davey RA,Zuo Y,Cunningham JM

更新日期：1999-05-01 00:00:00

abstract：:The interaction of the human immunodeficiency virus (HIV) Gag protein with the plasma membrane of a cell is a critical event in the assembly of HIV particles. The matrix protein region (MA) of HIV type 1 (HIV-1) Pr55Gag has previously been demonstrated to confer membrane-binding properties on the precursor polyprotein...

journal_title：Journal of virology

authors： Spearman P,Horton R,Ratner L,Kuli-Zade I

更新日期：1997-09-01 00:00:00

abstract：:The temperature-sensitive defects of virus mutants isolated from L cells persistently infected with Newcastle disease virus (NDV) were analyzed. Genetic grouping of the mutants by complementation tests was attempted by using several different methods, including yield analysis, RNA synthesis, and heterozygote formation...

journal_title：Journal of virology

authors： Preble OT,Youngner JS

更新日期：1973-09-01 00:00:00

abstract：:Engineered recombinant viruses expressing reporter genes have been developed for real-time monitoring of replication and for mass screening of antiviral inhibitors. Recently, we reported using a reverse genetics system to develop the first recombinant reporter rotaviruses (RVs) that expressed NanoLuc (NLuc) luciferase...

journal_title：Journal of virology

authors： Kanai Y,Kawagishi T,Nouda R,Onishi M,Pannacha P,Nurdin JA,Nomura K,Matsuura Y,Kobayashi T

更新日期：2019-02-05 00:00:00

abstract：:The simian picornaviruses were isolated from various primate tissues during the development of general tissue culture methods in the 1950s to 1970s or from specimens derived from primates used in biomedical research. Twenty simian picornavirus serotypes are recognized, and all are presently classified within the Enter...

journal_title：Journal of virology

authors： Oberste MS,Maher K,Pallansch MA

更新日期：2002-02-01 00:00:00

abstract：:The induction of alpha/beta interferon (IFN-alpha/beta) genes constitutes one of the first responses of the cell to virus infection. The IFN-beta gene is constitutively repressed in uninfected cells and is transiently activated after virus infection. In this work we demonstrate that histone deacetylation regulates the...

journal_title：Journal of virology

authors： Shestakova E,Bandu MT,Doly J,Bonnefoy E

更新日期：2001-04-01 00:00:00

abstract：:Autographa californica nuclear polyhedrosis virus (AcMNPV) is a double-stranded DNA virus that expresses several immediate-early genes under the control of different promoters. The expression of one of these transcription units, IE-N, is shown here, by a transient expression assay, to be regulated by both cis- and tra...

journal_title：Journal of virology

authors： Carson DD,Summers MD,Guarino LA

更新日期：1991-02-01 00:00:00

abstract：:Nipah virus (NiV), of the family Paramyxoviridae, was isolated in 1999 in Malaysia from a human fatality in an outbreak of severe human encephalitis, when human infections were linked to transmission of the virus from pigs. Consequently, a swine vaccine able to abolish virus shedding is of veterinary and human health ...

journal_title：Journal of virology

authors： Weingartl HM,Berhane Y,Caswell JL,Loosmore S,Audonnet JC,Roth JA,Czub M

更新日期：2006-08-01 00:00:00

abstract：:PM2 DNA was prepared with different superhelical densities (sigma) in order to examine the relationship betweenn supercoiling and the occurrence of a region(s) of unpaired bases in this DNA. A previous study showed that CH3HgOH reacts with native superhelical PM2 DNA more rapidly than the nicked form II. This evaluati...

journal_title：Journal of virology

authors： Woodworth-Gutai M,Lebowitz J

更新日期：1976-04-01 00:00:00

abstract：:ts1 and ts7, two temperature-sensitive mutants of Moloney murine leukemia virus strain TB induce hind-limb paralysis in 100% of CFW/D mice injected. These two paralytogenic mutants also share a defect in their inability to process the env precursor protein, Pr80env, at the restrictive temperature. To identify the muta...

journal_title：Journal of virology

authors： Yuen PH,Malehorn D,Knupp C,Wong PK

更新日期：1985-05-01 00:00:00

abstract：:The cytopathic effect (CPE) seen with some subgroups of avian sarcoma and leukosis virus (ASLV) is associated with viral Env activation of the death-promoting activity of TVB (a tumor necrosis factor receptor-related receptor that is most closely related to mammalian TNF-related apoptosis-inducing ligand [TRAIL] recep...

journal_title：Journal of virology

authors： Klucking S,Collins AS,Young JA

更新日期：2005-07-01 00:00:00

abstract：:Utilizing the isolated left and right halves of both adenovirus type 2 and the nondefective adenovirus simian virus 40 hybrid (Ad2(+)ND(1)), studies were undertaken to find the site on the DNA molecules at which replication begins. The data are consistent with several models which include an initiation event at both e...

journal_title：Journal of virology

authors： Horwitz MS

更新日期：1974-05-01 00:00:00

abstract：:Defined segments of the transmembrane envelope glycoprotein (gp45) of equine infectious anemia virus were expressed as TrpLE fusion proteins and examined for their reactivity in Western immunoblots against a diverse panel of equine immune sera. The most immunogenic region of gp45 was localized to its amino terminus, p...

journal_title：Journal of virology

authors： Chong YH,Ball JM,Issel CJ,Montelaro RC,Rushlow KE

更新日期：1991-02-01 00:00:00

abstract：:Primary sympathetic neuronal cultures were maintained for up to 5 weeks after inoculation with herpes simplex virus (HSV) without evidence of viral infection. Upon deprivation of nerve growth factor, the cultures produced infectious HSV, indicating that the cultures harbored latent HSV. This study demonstrates a funct...

journal_title：Journal of virology

authors： Wilcox CL,Johnson EM Jr

更新日期：1987-07-01 00:00:00

abstract：:In adenovirus-infected cells, the epidermal growth factor receptor (EGF-R) is internalized from the cell surface via endosomes and is degraded, and the E3 10,400-dalton protein (10.4K protein) is required for this effect (C. R. Carlin, A. E. Tollefson, H. A. Brady, B. L. Hoffman, and W. S. M. Wold, Cell 57:135-144, 19...

journal_title：Journal of virology

authors： Tollefson AE,Stewart AR,Yei SP,Saha SK,Wold WS

更新日期：1991-06-01 00:00:00

abstract：:A porcine rotavirus (prv), variant 4F, isolated in tissue culture from the feces of a Chinese pig with diarrhea, was found to have become highly pathogenic when passaged in gnotobiotic piglets (J. C. Bridger, B. Burke, G. M. Beards, and U. Desselberger, J. Gen. Virol. 73:3011-3015, 1992). Comparison with the closely r...

journal_title：Journal of virology

authors： Tauscher GI,Desselberger U

更新日期：1997-01-01 00:00:00

abstract：:Measles virus (MV) interacts with cellular receptors on the surface of peripheral blood lymphocytes (PBL) which mediate virus binding and uptake. Simultaneously, the direct contact of the viral glycoproteins with the cell surface induces a negative signal blocking progression to the S phase of the cell cycle, resultin...

journal_title：Journal of virology

authors： Erlenhoefer C,Wurzer WJ,Löffler S,Schneider-Schaulies S,ter Meulen V,Schneider-Schaulies J

更新日期：2001-05-01 00:00:00

abstract：:Human respiratory syncytial virus (HRSV) is the most important cause of acute respiratory disease in infants. Two major subgroups (A and B) have been identified based on antigenic differences in the attachment G protein. Antigenic variation between and within the subgroups may contribute to reinfections with these vir...

journal_title：Journal of virology

authors： Zlateva KT,Lemey P,Moës E,Vandamme AM,Van Ranst M

更新日期：2005-07-01 00:00:00

abstract：:Human immunodeficiency virus type 1 contains a transmembrane glycoprotein with an unusually long cytoplasmic domain. To determine the role of this domain in virus replication, a series of single nucleotide changes that result in the insertion of premature termination codons throughout the cytoplasmic domain has been c...

journal_title：Journal of virology

authors： Dubay JW,Roberts SJ,Hahn BH,Hunter E

更新日期：1992-11-01 00:00:00

abstract：:Accurate and sensitive quantitation of infectious human immunodeficiency virus (HIV) has been difficult to achieve. In this report, a quantitative focal immunoassay (FIA) for HIV was developed using human HeLa cells rendered susceptible to HIV infection by introduction of the CD4 gene via a retrovirus vector. Infected...

journal_title：Journal of virology

authors： Chesebro B,Wehrly K

更新日期：1988-10-01 00:00:00

abstract：:We have recovered a virion from defective cDNA of Sendai virus (SeV) that is capable of self-replication but incapable of transmissible-virion production. This virion delivers and expresses foreign genes in infected cells, and this is the first report of a gene expression vector derived from a defective viral genome o...

journal_title：Journal of virology

authors： Li HO,Zhu YF,Asakawa M,Kuma H,Hirata T,Ueda Y,Lee YS,Fukumura M,Iida A,Kato A,Nagai Y,Hasegawa M

更新日期：2000-07-01 00:00:00

abstract：:Type 1 human immunodeficiency viruses encoding mutated nef reading frames are 10- to 30-fold less infectious than are isogenic viruses in which the nef gene is intact. This defect in infectivity causes nef-negative viruses to grow at an attenuated rate in vitro. To investigate the mechanism of Nef-mediated enhancement...

journal_title：Journal of virology

authors： Pandori MW,Fitch NJ,Craig HM,Richman DD,Spina CA,Guatelli JC

更新日期：1996-07-01 00:00:00

abstract：:The hepatitis B virus X protein (HBX) is essential for the establishment of HBV infection in vivo and exerts a pleiotropic effect on diverse cellular functions. The yeast two-hybrid system had indicated that HBX could interact with two subunits of the 26S proteasome. Here we demonstrate an association in vivo of HBX w...

journal_title：Journal of virology

authors： Hu Z,Zhang Z,Doo E,Coux O,Goldberg AL,Liang TJ

更新日期：1999-09-01 00:00:00

abstract：:The replication of porcine circovirus type 1 (PCV1) is thought to occur by rolling-circle replication (RCR), whereby the introduction of a single-strand break generates a free 3'-hydroxyl group serving as a primer for subsequent DNA synthesis. The covalently closed, single-stranded genome of PCV1 replicates via a doub...

journal_title：Journal of virology

authors： Steinfeldt T,Finsterbusch T,Mankertz A

更新日期：2006-07-01 00:00:00

abstract：:Infection of quiescent cells by human cytomegalovirus (HCMV) elicits severe cell cycle deregulation, resulting in a G(1)/S arrest, which can be partly attributed to the inactivation of the anaphase-promoting complex (APC). As we previously reported, the premature phosphorylation of its coactivator Cdh1 and/or the diss...

journal_title：Journal of virology

authors： Tran K,Kamil JP,Coen DM,Spector DH

更新日期：2010-10-01 00:00:00