Abstract:
:In 33 renal allograft recipient-donor pairs, B and T lymphocyte complement-dependent cytotoxicity crossmatches and mixed lymphocyte culture (MLC) blocking experiments were performed and the results were correlated with graft outcome. MLC blocking particularly in the unidirectional culture against donor-stimulating cells, was highly correlated with the presence of complement-dependent cytotoxicity antibodies against donor B lymphocytes. Grafts in both MLC blocking and B lymphocyte crossmatch-positive groups fared equally as well as those without positive tests. No difference in graft outcome was noted when the presence or absence of MLC blocking was examined in relationship to positive or negative B lymphocyte complement-dependent cytotoxicity crossmatching.
journal_name
Transplantationjournal_title
Transplantationauthors
Ettenger RB,Opelz G,Walker J,Terasaki PI,Uittenbogaart C,Pennisi AJ,Malekzadeh MH,Fine RNdoi
10.1097/00007890-197804000-00002subject
Has Abstractpub_date
1978-04-01 00:00:00pages
169-72issue
4eissn
0041-1337issn
1534-6080journal_volume
25pub_type
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