Management of Patients Who Receive an Organ Transplant Abroad and Return Home for Follow-up Care: Recommendations From the Declaration of Istanbul Custodian Group.

abstract：:In a retrospective review of fifty heart, lung, and heart-lung recipients receiving cyclosporine, forty-six (92%) were hypertensive. This hypertension was managed with either prazosin (n = 29) or nifedipine (n = 17). Renal function was assessed by creatinine clearance estimation and found to be significantly better in...

journal_title：Transplantation

authors： Kirk AJ,Omar I,Bateman DN,Dark JH

更新日期：1989-09-01 00:00:00

abstract：:Donor-specific transfusion effects were studied in the ACI-to-Lewis rat heterotopic heart allograft model using cyclosporine immunosuppression. Low-dose CsA for 1 week plus a single fresh or stored DST given 1 day before allografting significantly prolonged graft survival over CsA therapy alone (median survival time 2...

journal_title：Transplantation

authors： Brunson ME,Tchervenkov JI,Alexander JW

更新日期：1991-09-01 00:00:00

abstract：:This study investigates the possibility that the active enhancing properties of bone marrow (BM) cells may be related to Ia-like determinants on their surface membranes. Less chromium was released on a cell per cell basis from nucleated baboon BM cells used as targets in complement-dependent cytotoxicity than from lab...

journal_title：Transplantation

authors： Smit JA,Myburgh JA,Gaillard VJ

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:We previously showed that bortezomib (BTZ) partially depletes plasma cells, yet has limited efficacy for desensitization in kidney transplant candidates when up to 16 doses is given. METHODS:This study aimed to determine the safety and efficacy of 32 doses of BTZ (1.3 mg/m of body surface area) in 10 highly...

journal_title：Transplantation

authors： Moreno Gonzales MA,Gandhi MJ,Schinstock CA,Moore NA,Smith BH,Braaten NY,Stegall MD

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Bioluminescence imaging (BLI) modalities are being developed to monitor islet transplant mass and function in vivo. The aim of this study was to use the BLI system to determine how the change in functional islet mass correlated to metabolic abnormalities during the course of alloimmune rejection in a murine ...

journal_title：Transplantation

authors： Chen X,Zhang X,Larson CS,Baker MS,Kaufman DB

更新日期：2006-05-27 00:00:00

abstract：:Graft-versus-host disease (GVHD)* is a frequent complication of allogeneic bone marrow transplantation. The potentially beneficial effect of phototherapy for treatment of cutaneous manifestations of GVHD led us to investigate retrospectively the effect of this therapy in a larger series of patients. Eleven patients wi...

journal_title：Transplantation

authors： Aubin F,Brion A,Deconinck E,Plouvier E,Hervé P,Humbert P,Cahn JY

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:Modification of the aminoacid sequence of peptides derived from the HLA class I heavy chain in combination with computer rational design resulted in the development of a peptide, RDP1258, with enhanced immunosuppressive activity. METHODS:We evaluated the activity of this peptide, analyzing infiltrate by imm...

journal_title：Transplantation

authors： Brouard S,Cuturi MC,Pignon P,Buelow R,Loth P,Moreau A,Soulillou JP

更新日期：1999-06-27 00:00:00

abstract：BACKGROUND:T lymphocyte activation mediated by CD28 costimulation plays a critical role in graft rejection. Plant alkaloid tetrandrine, purified from a Chinese antirheumatic herb, is a potent immunosuppressant. Here, we examined its effects on several CD28-costimulated T-cell activities. In addition, such effects were ...

journal_title：Transplantation

authors： Lai JH,Ho LJ,Kwan CY,Chang DM,Lee TC

更新日期：1999-11-15 00:00:00

abstract：:Acute rejection episodes still occur after kidney transplantation in spite of modern immunosuppressive protocols including combined tacrolimus, mycophenolate mofetil, and prednisolone. The authors present seven cases of biopsy-proven acute rejection after kidney transplantation refractory to conventional rejection the...

journal_title：Transplantation

authors： Kumlien G,Genberg H,Shanwell A,Tydén G

更新日期：2005-01-15 00:00:00

abstract：:It has been reported that cultured keratinocyte (CK) allografts are not rejected in mice, unlike in other species. Several reports have suggested that mouse CK allografts are incapable of stimulating a primary alloresponse, including sensitization of recipients to alloantigens. In this study, we investigated the immun...

journal_title：Transplantation

authors： Cairns BA,deSerres S,Matsui M,Frelinger JA,Meyer AA

更新日期：1994-07-15 00:00:00

abstract：BACKGROUND:Diagnosing acute rejection (AR) in kidney transplant recipients typically requires an invasive kidney biopsy. A previous study has suggested that expression of five genes in peripheral blood can indicate the presence of AR in American pediatric kidney transplant recipients. This study aims to validate if the...

journal_title：Transplantation

authors： Lee A,Jeong JC,Choi YW,Seok HY,Kim YG,Jeong KH,Moon JY,Lee TW,Ihm CG,Jeon HJ,Koo TY,Ahn C,Lim SJ,Yang J,Lee SH

更新日期：2014-10-15 00:00:00

abstract：:Total lymphoid irradiation (TLI) induces a unique state of immunosuppression. Although permanent bone marrow chimerism has been obtained in rodents prepared by TLI, uniform marrow engraftment has been more difficult to obtain in larger mammals. Accordingly, studies were performed to assess the immunologic perturbation...

journal_title：Transplantation

authors： Lowry RP,Carpenter CB,Gurley KE,Merrill JP

更新日期：1983-07-01 00:00:00

abstract：:Over the last decade there have been major advances in all aspects of liver transplantation with the consequence that the number of patients who could benefit from the procedure is increasing. As a result, the number of patients listed for liver transplantation is growing while the donor pool is remaining constant or ...

journal_title：Transplantation

authors： Neuberger J,Ubel PA

更新日期：2000-11-27 00:00:00

abstract：:Intercellular adhesion molecule-1 (ICAM-1) induction on hepatocytes was investigated in relation to acute liver allograft rejection, CMV infection, and systemic bacterial infections. Twenty-four liver transplant recipients underwent an episode of acute rejection, 13 developed a symptomatic clinical CMV infection, and ...

journal_title：Transplantation

authors： Lautenschlager IT,Höckerstedt KA

更新日期：1993-12-01 00:00:00

abstract：:Various autoantibodies were screened in 53 long-term survivors after allogeneic bone marrow transplantation. Among them, 40 displayed chronic graft-versus-host disease, with clinical features reminiscent of collagen diseases, especially scleroderma, Sjögren's syndrome, and autoimmune hepatitis. Antinuclear, anti-smoot...

journal_title：Transplantation

authors： Rouquette-Gally AM,Boyeldieu D,Prost AC,Gluckman E

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Graft versus host disease (GvHD) is the main complication after hematopoietic stem-cell transplantation.Extracorporeal photochemotherapy (ECP) is a cell therapy currently used for the treatment of T-cell–mediated diseases and seems as a valuable second-line therapy for patients suffering from steroid-refract...

journal_title：Transplantation

authors： Hannani D,Merlin E,Gabert F,Laurin D,Deméocq F,Chaperot L,Kanold J,Plumas J

更新日期：2010-12-15 00:00:00

abstract：:Several studies have reported the development of antiidiotypic antibodies to anti-HLA alloantibodies in renal allograft transplant recipients, postulating their potential beneficial role in allograft survival. In order to evaluate the role of anti-HLA antiidiotypic antibodies in human liver transplant recipients and t...

journal_title：Transplantation

authors： Chauhan B,Phelan DL,Marsh JW,Mohanakumar T

更新日期：1993-08-01 00:00:00

abstract：:Crigler-Najjar type 1 disease (CNS1) is the result of a genetic defect, leading to complete functional loss of an enzyme which glucuronidates bilirubin. As a consequence, unconjugated bilirubin accumulates and may cause kernicterus, the most serious complication in adolescents. Phototherapy effectively adjusts bilirub...

journal_title：Transplantation

authors： Schauer R,Lang T,Zimmermann A,Stangl M,Da Silva L,Schildberg FW,Rau HG

更新日期：2002-01-15 00:00:00

abstract：:The individual effects of verapamil and 2 antioxidants on perfused rat liver nucleoside triphosphate (NTP) recovery following cold storage in University of Wisconsin (UW) solution was assessed using 31P nuclear magnetic resonance spectroscopy. The pharmacological agents were added to UW solution and were present only ...

journal_title：Transplantation

authors： Bowers JL,Neymark E,Cook CU,Clouse ME

更新日期：1994-06-15 00:00:00

abstract：:Monoclonal antibodies to CD3 have been shown to activate T cells in vivo and in vitro but have also been shown to render T cells anergic in vitro. In this study G4.18, a mouse IgG3 mAb, was produced that appeared to recognize CD3 by its binding to all peripheral T cells, including a population not recognized by mAb to...

journal_title：Transplantation

authors： Nicolls MR,Aversa GG,Pearce NW,Spinelli A,Berger MF,Gurley KE,Hall BM

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Deoxyspergualin (DSG), a potent immunosuppressive drug, has been clinically used as a rescue therapy for acute graft rejection. However, DSG has severe adverse effects that limits its use. Here, we examined the optimized therapeutic protocol for DSG using chronopharmacological profiles of it. METHODS:First,...

journal_title：Transplantation

authors： Uchida H,Kobayashi E,Matsuda K,Mizuta K,Sugimoto K,Kawarasaki H,Hashizume K,Fujimura A

更新日期：1999-05-15 00:00:00

abstract：:Spleen cells obtained from C57BL/Ks (Ks, H-2d) mice carrying passively enhanced Sarcoma I (Sa I, H-2a) tumors were tested for alloantibody formation, lymphocyte blastogenesis, antibody-dependent cellular cytotoxicity, and cell to cell cytotoxicity. Assays were usually performed approximately 6 weeks after tumor inocul...

journal_title：Transplantation

authors： Giorgi JV,Tokuda S,Goldberg EH,Shen FW

更新日期：1978-03-01 00:00:00

abstract：:To investigate the causes of impaired liver function (LF)* after BMT, 88 patients were included for analysis of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, transplant methods, preconditioning regimens, and graft-versus-host disease (GVHD). Fifty of them (56.8%) developed abnormal LF after BMT and a...

journal_title：Transplantation

authors： Chen PM,Liu JH,Fan FS,Hsieh RK,Wei CH,Liu RS,Tzeng CH

更新日期：1995-04-27 00:00:00

abstract：:After the progressive improvement in the results of organ transplantation we now face the challenge of shortage in organ supply. The decreasing number of organ retrievals performed in 1990 at our hospital has raised questions concerning loss of potential organ donors and opposition to donation by the next of kin. We i...

journal_title：Transplantation

authors： Faltin DL,Jeannet M,Suter PM

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The need to find a safe, effective liver support system for patients with fulminant hepatic failure (FHF) continues to be unmet. A system using immortalized human hepatocytes was originally developed in the early 1990s. A modified version of the initial extracorporeal liver-assist device (ELAD) was recently ...

journal_title：Transplantation

authors： Millis JM,Cronin DC,Johnson R,Conjeevaram H,Conlin C,Trevino S,Maguire P

更新日期：2002-12-27 00:00:00

abstract：:Mice of the B10 background that are class II I-E nonexpressing demonstrate a relative resistance to neonatal induction of tolerance of class I alloantigens from I-E-expressing B10 strains. The majority of these injected mice delete donor-responsive and "I-E-reactive" (V beta 11+) cells in the immediate postinoculation...

journal_title：Transplantation

authors： Nassiri M,Viciana A,Streilein JW,Ruiz P

更新日期：1993-12-01 00:00:00

abstract：:Short-term outcomes of solid organ transplantation have improved dramatically over the past several decades; however, long-term survival has remained static over the same period, and chronic rejection remains a major cause of graft failure. The importance of donor, or "passenger," lymphocytes to the induction of toler...

journal_title：Transplantation

authors： Prosser AC,Kallies A,Lucas M

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Many recipients of lung transplants from brain-dead donors develop bronchiolitis obliterans, a manifestation of chronic rejection. It has been shown that brain death increases inflammatory mediators and accelerates acute rejection in kidney, liver, and heart transplants. In this study, the authors investigat...

journal_title：Transplantation

authors： Zweers N,Petersen AH,van der Hoeven JA,de Haan A,Ploeg RJ,de Leij LF,Prop J

更新日期：2004-11-15 00:00:00

abstract：BACKGROUND:Both T and B cells have been shown to be implicated in the pathogenesis of bronchiolitis obliterans syndrome, which is considered to represent chronic lung allograft rejection. However, the relative contributions of T cells and alloantibodies in the pathogenesis of the disease are still unknown. In this stud...

journal_title：Transplantation

authors： Higuchi T,Jaramillo A,Kaleem Z,Patterson GA,Mohanakumar T

更新日期：2002-09-15 00:00:00

abstract：:Using C1q binding, Kg binding, and Raji cell radioimmunoassays, the relationship between renal allograft rejection and the circulating immune complexes was examined in 90 patients with renal transplants. The data showed that there was a significant quantitative correlation between C1q-binding and Raji-cell-binding act...

journal_title：Transplantation

authors： Fukuda M

更新日期：1983-08-01 00:00:00