Active enhancement in the primate by bone marrow I. Ia-like determinants on nucleated bone marrow cells.

abstract：:Histoincompatibility was analyzed to describe as precisely as possible the sequence of gross morphological events taking place during allograft rejection among closely related conspecifics from a natural population of the bisexual lizard Cnemidophorus tigris. Two types of rejection were noted, depending on whether the...

journal_title：Transplantation

authors： Cuellar O,Smart C

更新日期：1977-08-01 00:00:00

abstract：:Fine-needle aspiration biopsies were used for clinical monitoring of liver allografts; 21 patients with an inflammatory episode of acute rejection (12.0 +/- 3.3 CIU at the peak) were studied; all episodes were reversible. The inflammatory infiltrate consisted mainly of lymphoid cells, including lymphoid blasts, with i...

journal_title：Transplantation

authors： Lautenschlager I,Höckerstedt K,Salmela K,Isoniemi H,Holmberg C,Jalanko H,Häyry P

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Better preservation strategies for the storage of donation after circulatory death grafts are essential to improve graft function and to increase the kidney donor pool. We compared continuous normothermic ex vivo kidney perfusion (NEVKP) with hypothermic anoxic machine perfusion (HAMP) and static cold storag...

journal_title：Transplantation

authors： Urbanellis P,Hamar M,Kaths JM,Kollmann D,Linares I,Mazilescu L,Ganesh S,Wiebe A,Yip PM,John R,Konvalinka A,Mucsi I,Ghanekar A,Bagli DJ,Robinson LA,Selzner M

更新日期：2020-05-01 00:00:00

abstract：:The immunosuppressive activity of niridazole in unmatched kidney allografts in nephrectomized dogs was studied. The drug alone was not effective, but improved survival when used with azathioprine and prednisolone or azathioprine alone. However, niridazole was toxic in dogs in the doses used (25 or 50 mg/kg/day). ...

journal_title：Transplantation

authors： Sokucu N,Caridis DT,Moran J

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:In the development of chronic kidney allograft rejection acute rejection (AR) is the single most important risk factor. Although Cyclosporin A (CsA) medication has decreased the incidence of AR, chronic rejection (CR) is still the major reason for late allograft loss. Platelet-derived growth factor (PDGF) is...

journal_title：Transplantation

authors： Savikko J,Kallio EA,Taskinen E,von Willebrand E

更新日期：2002-02-27 00:00:00

abstract：BACKGROUND:Recently, methylxanthines such as pentoxifylline (PTX) were shown to be immunosuppressive in vitro. Unfortunately, when used in transplant patients, PTX was poorly active as an immunosuppressant. Here we report that the new methylxanthine derivative A802715 not only is more active than PTX, it also suppresse...

journal_title：Transplantation

authors： Lin Y,Goebels J,Rutgeerts O,Kasran A,Van Gool S,Ceuppens J,Schönharting M,Waer M

更新日期：1997-06-27 00:00:00

abstract：BACKGROUND:Tolerogenic dendritic cells (Tol-DCs) play a critical role in inducing and maintaining tolerance. Recognizing that both T-cell inactivation and activation are contingent on signals provided by DCs and that graft-specific activated T cells are major mediators of transplant rejection, we aimed to create an env...

journal_title：Transplantation

authors： Lan Z,Ge W,Arp J,Jiang J,Liu W,Gordon D,Healey D,DeBenedette M,Nicolette C,Garcia B,Wang H

更新日期：2010-12-27 00:00:00

abstract：:India with a population of 1.2 billion has a renal transplantation rate of 3.25 per million population. The major cause of chronic kidney disease is hypertension and diabetes. The crude and age-adjusted incidence rates of end-stage renal disease are estimated to be 151 and 232 per million population, respectively, in ...

journal_title：Transplantation

authors： Abraham G,Reddy YN,Amalorpavanathan J,Daniel D,Roy-Chaudhury P,Shroff S,Reddy Y

更新日期：2012-04-27 00:00:00

abstract：BACKGROUND:Uterus transplantation is a treatment for absolute uterine infertility and can be performed with living and deceased donors. Given the safety and increased utilization of robotic assistance with other gynecologic and transplant donor operations, we adopted a robot-assisted approach to donor hysterectomy. Thi...

journal_title：Transplantation

authors： Johannesson L,Koon EC,Bayer J,McKenna GJ,Wall A,Fernandez H,Martinez EJ,Gupta A,Ruiz R,Onaca N,Testa G

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Two apolipoprotein L1 gene (APOL1) renal-risk variants in donors and African American (AA) recipient race are associated with worse allograft survival in deceased-donor kidney transplantation (DDKT) from AA donors. To detect other factors impacting allograft survival from deceased AA kidney donors, APOL1 ren...

journal_title：Transplantation

authors： Freedman BI,Pastan SO,Israni AK,Schladt D,Julian BA,Gautreaux MD,Hauptfeld V,Bray RA,Gebel HM,Kirk AD,Gaston RS,Rogers J,Farney AC,Orlando G,Stratta RJ,Mohan S,Ma L,Langefeld CD,Bowden DW,Hicks PJ,Palmer ND,Pala

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Steroid-resistant acute rejection is a risk factor for inferior renal allograft outcome. METHODS:From 873 kidney transplant recipients (1995-2005), 108 patients with a first rejection episode were selected for study using strict inclusion criteria and clinical endpoint definition. We aimed to predict respon...

journal_title：Transplantation

authors： Rekers NV,Bajema IM,Mallat MJ,Zuidwijk K,Anholts JD,Goemaere N,Haasnoot GW,van Groningen MC,van Kooten C,de Fijter JW,Claas FH,Eikmans M

更新日期：2012-09-27 00:00:00

abstract：:Limited recovery of contractile function and loss of coronary reactivity have been observed following prolonged hypothermic storage and transplantation of the heart. Since lipid peroxidation has a significant role in these deficits, we investigated the cardioprotective effects of a 21-aminosteroid. U74389G, 3 mg/kg i....

journal_title：Transplantation

authors： Duguay P,Chen H,Daloze P,Dumont L

更新日期：1996-04-15 00:00:00

abstract：:The individual effects of verapamil and 2 antioxidants on perfused rat liver nucleoside triphosphate (NTP) recovery following cold storage in University of Wisconsin (UW) solution was assessed using 31P nuclear magnetic resonance spectroscopy. The pharmacological agents were added to UW solution and were present only ...

journal_title：Transplantation

authors： Bowers JL,Neymark E,Cook CU,Clouse ME

更新日期：1994-06-15 00:00:00

abstract：BACKGROUND:Focal segmental glomerulosclerosis (FSGS) recurs after kidney transplantation in more than 30% of cases and can lead to allograft loss. Serum soluble urokinase-type plasminogen activator receptor (suPAR) is implicated in the pathogenesis of native and recurrent FSGS. METHODS:We conducted a retrospective stu...

journal_title：Transplantation

authors： Alachkar N,Wei C,Arend LJ,Jackson AM,Racusen LC,Fornoni A,Burke G,Rabb H,Kakkad K,Reiser J,Estrella MM

更新日期：2013-10-15 00:00:00

abstract：:If transplantation of endocrine tissue is to become a therapy for a significant number of insulin-dependent diabetic individuals, tissue sources other than adult human islets will be required. Because human fetal pancreatic cells may offer that alternative, we have tried to find the optimal combination of tissue cultu...

journal_title：Transplantation

authors： Beattie GM,Otonkoski T,Lopez AD,Hayek A

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Circulation of leukocytes via blood, tissue and lymph is integral to adaptive immunity. Afferent lymphatics form CCL21 gradients to guide dendritic cells and T cells to lymphatics and then to draining lymph nodes (dLN). Vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 (V...

journal_title：Transplantation

authors： Iwami D,Brinkman CC,Bromberg JS

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Fatty livers are more prone to primary nonfunction after transplantation. It is known that cell injury is strongly associated with alterations in the content and composition of membrane lipids. We assumed that plasma membrane (PM) fluidity, which is the most important property of the membrane, differed betwe...

journal_title：Transplantation

authors： Fukumori T,Ohkohchi N,Tsukamoto S,Satomi S

更新日期：1999-01-27 00:00:00

abstract：:Sequential titers of five different humoral antibodies (antirat erythrocyte, antisheep erythrocyte, isoantibodies, rheumatoid factors, and serum agglutinators) were simultaneously performed on 20 patients with renal transplants, 12 patients with skin transplants, and 2 patient populations (one hospitalized and one amb...

journal_title：Transplantation

authors： Waller M,Pierce JC,Lee HM,Levinson HJ

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Skin-autofluorescence (skin-AF) noninvasively measures the tissue accumulation of advanced glycation end products (AGEs). AGEs are nephrotoxic and potential effectors of cardiovascular mortality. We investigated whether skin-AF predicted graft loss after kidney transplantation. METHODS:A total of 302 renal ...

journal_title：Transplantation

authors： Hartog JW,Gross S,Oterdoom LH,van Ree RM,de Vries AP,Smit AJ,Schouten JP,Nawroth PP,Gans RO,van Son WJ,Bierhaus A,Bakker SJ

更新日期：2009-04-15 00:00:00

abstract：BACKGROUND:Specific tolerance after combined kidney and bone marrow transplantation for multiple myeloma with end-stage renal disease through mixed lymphohematopoietic chimerism has been achieved, as evidenced by prolonged normal renal function without ongoing immunosuppression. METHODS:To achieve potent antimyeloma r...

journal_title：Transplantation

authors： Spitzer TR,Sykes M,Tolkoff-Rubin N,Kawai T,McAfee SL,Dey BR,Ballen K,Delmonico F,Saidman S,Sachs DH,Cosimi AB

更新日期：2011-03-27 00:00:00

abstract：:To formulate a model predicting survival after liver retransplantation, we analyzed in detail the last 150 cases of hepatic retransplantation at UCLA. Cox proportional hazards regression analysis identified five variables that demonstrated independent simultaneous prognostic value in estimating patient survival after ...

journal_title：Transplantation

authors： Markmann JF,Gornbein J,Markowitz JS,Levy MF,Klintmalm GB,Yersiz H,Morrisey M,Drazan K,Farmer DG,Ghobrial RM,Goss J,Seu P,Martin P,Goldstein LI,Busuttil RW

更新日期：1999-02-15 00:00:00

abstract：:Mouse thyroid tissue was dissociated with collagenase, fixed in periodate-lysine-paraformaldehyde (PLP), and further dissociated with EDTA and trypsin to yield cell suspensions containing mainly follicle epithelial cells and vascular endothelial cells. H-2 complex antigens were detected on the vascular endothelial cel...

journal_title：Transplantation

authors： Parr EL,Lafferty KJ,Bowen KM,McKenzie IF

更新日期：1980-08-01 00:00:00

abstract：:Adult bone marrow-derived mesenchymal stem cells (MSCs) are multipotential cells capable of regenerating injured tissues. In addition to their multipotency, MSCs inhibit natural killer cell cytotoxicity and T-lymphocyte alloproliferation. Several immunosuppressive mechanisms have been described, including indoleamine ...

journal_title：Transplantation

authors： Selmani Z,Naji A,Gaiffe E,Obert L,Tiberghien P,Rouas-Freiss N,Carosella ED,Deschaseaux F

更新日期：2009-05-15 00:00:00

abstract：:Unilateral, intraorganal injection of parental lymph node cells into thyroid lobes of F1 hybrid rats elicited an intense, local graft-versus-host reaction within the injected lobes containing massive numbers of lymphocytes. Surprisingly, significant mononuclear cell infiltration was also seen within the contralateral ...

journal_title：Transplantation

authors： Konetzki WS,Streilein JW

更新日期：1978-05-01 00:00:00

abstract：:The prevalence of angiographically proven coronary artery disease (CAD) in adults with end-stage liver disease who undergo evaluation for liver transplantation is unknown; also it is unclear if cholestatic liver disease represents an independent risk factor. Patients with end-stage liver disease over age 50 having liv...

journal_title：Transplantation

authors： Carey WD,Dumot JA,Pimentel RR,Barnes DS,Hobbs RE,Henderson JM,Vogt DP,Mayes JT,Westveer MK,Easley KA

更新日期：1995-03-27 00:00:00

abstract：:Mice of the B10 background that are class II I-E nonexpressing demonstrate a relative resistance to neonatal induction of tolerance of class I alloantigens from I-E-expressing B10 strains. The majority of these injected mice delete donor-responsive and "I-E-reactive" (V beta 11+) cells in the immediate postinoculation...

journal_title：Transplantation

authors： Nassiri M,Viciana A,Streilein JW,Ruiz P

更新日期：1993-12-01 00:00:00

abstract：:Retrospectively we analyzed the histocompatibility data and clinical results of bone marrow transplantation in 51 patients who received marrow from unrelated donors (UD) from 1977 to 1987 at one of four UK BMT centers. We compared the results with those obtained in 51 transplants carried out at the same centers using ...

journal_title：Transplantation

authors： Howard MR,Hows JM,Gore SM,Barrett J,Brenner MK,Goldman JM,Gordon-Smith EC,Poynton C,Prentice HG,Whittaker JA

更新日期：1990-03-01 00:00:00

abstract：INTRODUCTION:This study examines the efficacy and toxicity of sirolimus used as primary immunosuppression in combination with reduced dose tacrolimus (calcineurin inhibitor [CI]-sparing regimen) or mycophenolate mofetil (CI-free regimen) in high-risk cadaveric renal transplantation. METHODS:Seventy subjects were treat...

journal_title：Transplantation

authors： Lo A,Egidi MF,Gaber LW,Amiri HS,Vera S,Nezakatgoo N,Gaber AO

更新日期：2004-04-27 00:00:00

abstract：:A series of rat monoclonal antibodies against the human leukocyte-common antigen were isolated and, by means of competitive binding assays with purified antigen, two distinct groups were defined that recognize different epitopes of the molecule. None of these antibodies were lytic with human complement, but when antib...

journal_title：Transplantation

authors： Bindon CI,Hale G,Clark M,Waldmann H

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:It is unclear if the category of acute rejection with intimal arteritis (ARV) is relevant to short- and long-term clinical outcomes and if the graft outcomes are affected by the severity of intimal arteritis. METHODS:One hundred forty-eight ARV episodes were reviewed and categorized according to the 2013 Ba...

journal_title：Transplantation

authors： Wu K,Budde K,Schmidt D,Neumayer HH,Rudolph B

更新日期：2015-08-01 00:00:00