Abstract:
:The individual effects of verapamil and 2 antioxidants on perfused rat liver nucleoside triphosphate (NTP) recovery following cold storage in University of Wisconsin (UW) solution was assessed using 31P nuclear magnetic resonance spectroscopy. The pharmacological agents were added to UW solution and were present only during organ storage. NTP recovery was significantly higher for the 24-hr UW + 40 microM verapamil group as compared with the 24-hr UW group. None of the other pharmacological agents caused a significant increase in NTP recovery. These findings suggest that addition of verapamil to UW organ preservation solution may result in better poststorage liver function.
journal_name
Transplantationjournal_title
Transplantationauthors
Bowers JL,Neymark E,Cook CU,Clouse MEsubject
Has Abstractpub_date
1994-06-15 00:00:00pages
1576-80issue
11eissn
0041-1337issn
1534-6080journal_volume
57pub_type
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