The management of T tube leaks in orthotopic liver transplant recipients with endoscopically placed nasobiliary catheters.

abstract：BACKGROUND:Solid-organ transplant recipients with pretransplant malignancies (PTM) have worse overall survival (OS) compared to recipients without history of malignancy. However, it is unknown whether the increased risk of mortality is due to recurrent cancer-related deaths. METHODS:All solid-organ transplant recipien...

journal_title：Transplantation

authors： Acuna SA,Sutradhar R,Kim SJ,Baxter NN

更新日期：2018-07-01 00:00:00

abstract：:Blocking activity of mouse pregnancy serum was investigated using a well defined one-way mixed lymphocyte culture and a cell-mediated microcytotoxicity test. Allogeneic (C57BL (H-2b) X CBA/Ca (H-2k)) and syngeneic (C57BL (H-2b) X C57BL (H-2b)) pregnancy and postpartum sera were found to stimulate rather than inhibit t...

journal_title：Transplantation

authors： Smith G

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:It is unclear whether ischemic preconditioning (IPC) of solid organs induces remote IPC (RIPC) in donors after brain death (DBD). METHODS:Outcomes in kidney recipients from 163 DBD in two randomized trials of liver IPC (5 min=62 and 10 min=101) were obtained retrospectively from the Scientific Registry of T...

journal_title：Transplantation

authors： Desai KK,Mora-Esteves C,Holland BK,Dikdan G,Fisher A,Wilson DJ,Koneru B

更新日期：2014-02-15 00:00:00

abstract：:Intestinal transplant is an established treatment of irreversible intestinal failure, unless complicated by advanced intestinal failure-associated liver disease, when liver-bowel transplant may be necessary. Finding at least moderate hepatic fibrosis or gastroesophageal varices (GOV) at oesophago-gastroduodenoscopy (O...

journal_title：Transplantation

authors： McKiernan PJ,Sharif K,Gupte GL

更新日期：2008-11-27 00:00:00

abstract：BACKGROUND:Despite the success rate of solitary pancreas transplantation in type 1 diabetes with preserved kidney function has greatly improved in recent years, a residual proportion of failures persists. METHODS:With the aim of investigating autoimmunity as an unrecognized cause of graft failure, we measured autoanti...

journal_title：Transplantation

authors： Occhipinti M,Lampasona V,Vistoli F,Bazzigaluppi E,Scavini M,Boggi U,Marchetti P,Bosi E

更新日期：2011-09-27 00:00:00

abstract：BACKGROUND:Dysregulation of the coagulation system due to inflammatory responses and cross-species molecular incompatibilities represents a major obstacle to successful xenotransplantation. We hypothesized that complement inhibition mediated by transgenic expression of human CD46 in pigs might also regulate the coagula...

journal_title：Transplantation

authors： Bongoni AK,Kiermeir D,Schnider J,Jenni H,Garimella P,Bähr A,Klymiuk N,Wolf E,Ayares D,Voegelin E,Constantinescu MA,Seebach JD,Rieben R

更新日期：2015-10-01 00:00:00

abstract：:Liver-derived dendritic cell (DC) progenitors propagated in liquid culture in granulocyte/macrophage colony-stimulating factor exhibit low levels both of cell surface MHC class II antigens and of counter-receptors for CTLA-4/CD28. They fail to stimulate allogeneic T cells in mixed leukocyte cultures. To evaluate their...

journal_title：Transplantation

authors： Rastellini C,Lu L,Ricordi C,Starzl TE,Rao AS,Thomson AW

更新日期：1995-12-15 00:00:00

abstract：:We describe a substrain of BB rats, BB/Pfd, characterized by a loss of autoimmune potential soon after onset of diabetes. When fresh syngeneic (BB/Pfd) islets (6 islets/g body weight) were transplanted under the kidney capsule of diabetic BB/Pfd rats 1-2 weeks after diabetes onset (n = 14), no recurrence of diabetes o...

journal_title：Transplantation

authors： Mathieu C,Kuttler B,Waer M,Bouillon R,Hahn HJ

更新日期：1994-08-15 00:00:00

abstract：BACKGROUND:Induction immunosuppressive therapy with the anti-T-cell antibody Thymoglobulin decreases the incidence of acute rejection in adult kidney transplant (KTx) recipients, but limited data are available for pediatric KTx recipients. METHODS:We conducted a historical cohort study to compare rates of survival, re...

journal_title：Transplantation

authors： Khositseth S,Matas A,Cook ME,Gillingham KJ,Chavers BM

更新日期：2005-04-27 00:00:00

abstract：:Hepatic tolerance to hypotension was assessed by changes in arterial ketone body ratio (KBR) and hepatic energy charge levels in experimental brain death induced by epidural ballooning in dogs, and compared with the hemorrhagic shock model. Systolic arterial blood pressure was significantly decreased from 182 mmHg to ...

journal_title：Transplantation

authors： Lin H,Okamoto R,Yamamoto Y,Maki A,Ueda J,Tokunaga Y,Yamamoto S,Mori K,Tanaka K,Yamaoka Y

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Human ehrlichiosis, a newly described zoonotic infection, can be classified as human monocytic ehrlichiosis (HME) or human granulocytic ehrlichiosis (HGE). Although the clinical manifestations of HME and HGE are similar, the type of leukocyte infected, the etiologic agent, and the tick vector are distinct. ...

journal_title：Transplantation

authors： Adachi JA,Grimm EM,Johnson P,Uthman M,Kaplan B,Rakita RM

更新日期：1997-10-27 00:00:00

abstract：BACKGROUND:It is important to develop new immunosuppressive agents without clinical drawbacks. In this article, we reveal the possibility of a chemically synthetic sulfonolipid that acts as a novel immunosuppressive drug. METHODS:We evaluated the immunosuppressive effect of 3-O-(6-deoxy-6-sulfono-beta-D-glucopyranosyl...

journal_title：Transplantation

authors： Matsumoto Y,Sahara H,Fujita T,Shimozawa K,Takenouchi M,Torigoe T,Hanashima S,Yamazaki T,Takahashi S,Sugawara F,Mizushina Y,Ohta K,Takahashi N,Gasa S,Jimbow K,Sakaguchi K,Sato N

更新日期：2002-07-27 00:00:00

abstract：:Preformed recipient HLA-specific antibodies can cause hyperacute rejection of a transplanted kidney if they are directed against mismatched donor HLA antigens. To avoid hyperacute rejection it is essential that recipient antibodies be identified during patient workup for transplantation and HLA antigens to which a pat...

journal_title：Transplantation

authors： Martin S

更新日期：2001-05-27 00:00:00

abstract：:While the immune privilege nature of the eye affords significant protection to corneal grafts, immunologic rejection is the leading cause of graft failure. Class II antigens are normally absent or expressed at very low levels in normal cornea. The role that class II antigens play in causing graft rejection is particul...

journal_title：Transplantation

authors： Ross J,Callanan D,Kunz H,Niederkorn J

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Survival following liver transplantation for hepatitis C virus (HCV) is significantly poorer than for liver transplants performed for other causes of chronic liver disease. The factors responsible for the inferior outcome in HCV+ recipients, and whether they differ from factors associated with survival in HC...

journal_title：Transplantation

authors： Velidedeoglu E,Mange KC,Frank A,Abt P,Desai NM,Markmann JW,Reddy R,Markmann JF

更新日期：2004-06-27 00:00:00

abstract：:Many severe metabolic deficiencies in children are caused by a single gene defect with a resultant single gene product deficiency. These diseases may be amenable to permanent cure using new techniques of gene transfer and cell transplantation. In many in vivo models of retroviral mediated gene therapy, a significant l...

journal_title：Transplantation

authors： Gilbert JC,Takada T,Stein JE,Langer R,Vacanti JP

更新日期：1993-08-01 00:00:00

abstract：:A panel of ethicists, organ procurement organization executives, physicians, and surgeons was convened by the sponsorship of the American Society of Transplant Surgeons to determine whether an ethically acceptable pilot trial could be proposed to provide a financial incentive for a family to consent to the donation of...

journal_title：Transplantation

authors： Arnold R,Bartlett S,Bernat J,Colonna J,Dafoe D,Dubler N,Gruber S,Kahn J,Luskin R,Nathan H,Orloff S,Prottas J,Shapiro R,Ricordi C,Youngner S,Delmonico FL

更新日期：2002-04-27 00:00:00

abstract：:Modification of pathogenic antibodies for autoimmune diseases illuminated the biologic relevance of B cells, plasma cells, and pathogenic antibodies in autoimmunity. They have also rejuvenated interest in how B cells mediate multiple effector functions that include antibody production, antigen presentation to T cells,...

journal_title：Transplantation

authors： Jordan SC,Ammerman N,Choi J,Huang E,Peng A,Sethi S,Najjar R,Toyoda M,Lim K,Louie S,Vo A

更新日期：2019-02-01 00:00:00

abstract：:Use of pulsatile perfusion to optimize outcomes in deceased donor kidney transplantation remains controversial. This study is a retrospective analysis of all cadaveric renal allografts procured locally by our center over a 3-year period. Kidney pairs were identified in which one kidney underwent pulsatile perfusion an...

journal_title：Transplantation

authors： Shah AP,Milgrom DP,Mangus RS,Powelson JA,Goggins WC,Milgrom ML

更新日期：2008-10-15 00:00:00

abstract：BACKGROUND:HLA-specific antibodies detected by solid phase assays are increasingly used to define unacceptable HLA antigen mismatches (UAM) before renal transplantation. The accuracy of this approach is unclear. METHODS:Day of transplant sera from 211 complement-dependent cytotoxicity crossmatch-negative patients were...

journal_title：Transplantation

authors： Zecher D,Bach C,Preiss A,Staudner C,Utpatel K,Evert M,Jung B,Bergler T,Böger CA,Spriewald BM,Banas B

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:We report long-term outcomes and side effects after transplantation for hepatocellular carcinoma (HCC) using de novo, sirolimus-based immunosuppression (IS). METHODS:A total of 70 patients with HCC (mean age: 54.4+/-7 years, female/male: 12/58) were transplanted and included in the study. Immunosuppression ...

journal_title：Transplantation

authors： Toso C,Meeberg GA,Bigam DL,Oberholzer J,Shapiro AM,Gutfreund K,Ma MM,Mason AL,Wong WW,Bain VG,Kneteman NM

更新日期：2007-05-15 00:00:00

abstract：BACKGROUND:CD154 mediates key facets of humoral and cellular immunity to alloantigens, and is tolerogenic to influenza antigens in primates. Barriers to CD154-based tolerance induction for primate cardiac allografts have not previously been defined. METHODS:Heterotopic cardiac allograft outcomes in cynomolgus monkeys ...

journal_title：Transplantation

authors： Azimzadeh AM,Pfeiffer S,Wu G,Schröder C,Zorn GL 3rd,Kelishadi SS,Ozkaynak E,Kehry M,Atkinson JB,Miller GG,Pierson RN 3rd

更新日期：2006-01-27 00:00:00

abstract：:Over the last decade there have been major advances in all aspects of liver transplantation with the consequence that the number of patients who could benefit from the procedure is increasing. As a result, the number of patients listed for liver transplantation is growing while the donor pool is remaining constant or ...

journal_title：Transplantation

authors： Neuberger J,Ubel PA

更新日期：2000-11-27 00:00:00

abstract：BACKGROUND:The aim of our study was to examine, in a recent cohort of kidney transplant recipients who have received modern immunosuppressive therapy, the respective role of cold ischemia time (CIT) and delayed graft function (DGF) on acute rejection (AR) rates and long-term graft survival. METHODS:We retrospectively ...

journal_title：Transplantation

authors： Mikhalski D,Wissing KM,Ghisdal L,Broeders N,Touly M,Hoang AD,Loi P,Mboti F,Donckier V,Vereerstraeten P,Abramowicz D

更新日期：2008-04-15 00:00:00

abstract：:Although FK506 has been widely investigated as a potent suppressor of organ allograft rejection in animals, little is known about the effect of FK506 on T cell responses to allografts in vivo. In the present study, we have studied the effect of FK506 on the induction of allocytolytic T lymphocyte using mice primed wit...

journal_title：Transplantation

authors： Maruyama M,Suzuki H,Yamashita N,Yano S

更新日期：1990-08-01 00:00:00

abstract：:We have used a polymerase chain reaction-based assay measuring polymorphic (CA)n repeats, a class of simple sequence repeats, to assess the success of allogeneic canine marrow transplants. Results were compared with those obtained with karyotype analysis of dividing cells in recipients that were sex mismatched with th...

journal_title：Transplantation

authors： Yu C,Ostrander E,Bryant E,Burnett R,Storb R

更新日期：1994-09-27 00:00:00

abstract：:Three strains of miniature swine, each homozygous for a different allele of the major histocompatibility locus (MHC), have been developed by a selective breeding scheme based on tissue typing of the offspring of each generation. Prior to breeding, the original parents were reciprocally immunized by skin grafts and lym...

journal_title：Transplantation

authors： Sachs DH,Leight G,Cone J,Schwarz S,Stuart L,Rosenberg S

更新日期：1976-12-01 00:00:00

abstract：:Recipient dogs were conditioned with 9.2 Gy of total-body irradiation followed by the infusion of bone marrow and peripheral blood leukocytes from a DLA-haploidentical littermate (N = 10) or a completely allogeneic unrelated donor (n = 9). Graft-vs.-host disease (GVHD) prophylaxis consisted of methotrexate (MTX) and c...

journal_title：Transplantation

authors： Deeg HJ,Severns E,Raff RF,Sale GE,Storb R

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Alcoholic liver disease has emerged as a leading indication for hepatic transplantation, although it is a controversial use of resources. We aimed to examine all aspects of liver transplantation associated with alcohol abuse. METHODS:Retrospective cohort analysis of 123 alcoholic patients with a median of 7...

journal_title：Transplantation

authors： Bellamy CO,DiMartini AM,Ruppert K,Jain A,Dodson F,Torbenson M,Starzl TE,Fung JJ,Demetris AJ

更新日期：2001-08-27 00:00:00

abstract：:Experimental studies of vein homografts in rats have shown prolonged patency resulting from an attenuated immune response. This study examined the response to Golden Syrian hamster vein xenografts. While one group of Sprague-Dawley rats served as a control, a second group was sensitized with 5 X 10(6) viable hamster s...

journal_title：Transplantation

authors： Jordan BP,Jones JW,Rodgers GH,Flye MW

更新日期：1985-11-01 00:00:00