Relationship between ABO blood group and levels of Gal alpha,3Galactose-reactive human immunoglobulin G.

Abstract:

BACKGROUND:The terminal Gal alpha1,3Galactose (alphaGal) determinant is present on all porcine glycoproteins and glycolipids, but is not expressed by human cells. Consequently human sera contain anti-alphaGal natural antibodies. The human blood group B antigen [Gal alpha1,3(Fuc1,2)Galactose] is differentiated from the alphaGal epitope by the presence of a fucosyl group. METHODS:To determine whether the expression of the B antigen has any effect on the level of alphaGal-reactive natural antibodies, equal numbers (n=12) of A, B, AB, and O serum samples were evaluated by ELISA and flow cytometry. RESULTS:A significant reduction in IgG alphaGal reactivity was observed with serum samples from B antigen-expressing donors (B, AB) relative to non-B antigen-expressing donors (A, O). CONCLUSIONS:These results are consistent with the possibility that anti-alphaGal antibodies in non-B antigen-expressing individuals include a subset that is reactive with the structurally related B antigen and that this subset is absent in B and AB individuals.

journal_name

Transplantation

journal_title

Transplantation

authors

McMorrow IM,Comrack CA,Nazarey PP,Sachs DH,DerSimonian H

doi

10.1097/00007890-199708150-00032

subject

Has Abstract

pub_date

1997-08-15 00:00:00

pages

546-9

issue

3

eissn

0041-1337

issn

1534-6080

journal_volume

64

pub_type

杂志文章
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    authors: Hewitt CW,Black KS,Fraser LA,Howard EB,Martin DC,Achauer BM,Furnas DW

    更新日期:1985-04-01 00:00:00

  • The clinical utility of whole blood versus plasma cytomegalovirus viral load assays for monitoring therapeutic response.

    abstract:BACKGROUND:In patients with cytomegalovirus (CMV) disease, regular monitoring of viral loads and treatment until negative are recommended. However, with more sensitive polymerase chain reaction (PCR) assays and cellular peripheral sample types, detection of low-level viremia is achievable. We compared a whole blood rea...

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    authors: Lisboa LF,Asberg A,Kumar D,Pang X,Hartmann A,Preiksaitis JK,Pescovitz MD,Rollag H,Jardine AG,Humar A

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  • Age-related differences in the effects of cyclosporine on lymphocyte intracellular free calcium.

    abstract::The effect of cyclosporine on lymphocyte intracellular free calcium [( Ca2+]i) is controversial, and potential age-related differences in lymphocyte CsA sensitivity have not been studied. We measured the mitogen-induced change in [Ca2+]i in peripheral blood lymphocytes (PBLs) following intravenous CsA infusion (5 mg/k...

    journal_title:Transplantation

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    更新日期:1991-08-01 00:00:00

  • Hepatocyte transplantation in a 4-year-old girl with peroxisomal biogenesis disease: technique, safety, and metabolic follow-up.

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    doi:10.1097/01.TP.0000077420.81365.53

    authors: Sokal EM,Smets F,Bourgois A,Van Maldergem L,Buts JP,Reding R,Bernard Otte J,Evrard V,Latinne D,Vincent MF,Moser A,Soriano HE

    更新日期:2003-08-27 00:00:00

  • Growth factor-induced mobilization of dendritic cells in kidney and liver of rhesus macaques: implications for transplantation.

    abstract::Hematopoietic growth factors (HGF) mobilize potential tolerogenic cells in transplant donors. Fms-like tyrosine kinase 3 ligand (Flt3L) mobilizes stem cells and dendritic cells (DCs) in human and nonhuman primate blood. Blood and renal and liver biopsies were obtained from untreated and Flt3L-mobilized rhesus macaques...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.tp.0000255320.00061.e9

    authors: Morelli AE,Coates PT,Shufesky WJ,Barratt-Boyes SM,Fung JJ,Demetris AJ,Thomson AW

    更新日期:2007-03-15 00:00:00

  • Long-term survival of donor-specific pancreatic islet xenografts in fully xenogeneic chimeras (WF rat----B10 mouse).

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    journal_title:Transplantation

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    doi:10.1097/00007890-199202010-00005

    authors: Zeng YJ,Ricordi C,Tzakis A,Rilo HL,Carroll PB,Starzl TE,Ildstad ST

    更新日期:1992-02-01 00:00:00

  • Pretransplant immunologic risk assessment of kidney transplant recipients with donor-specific anti-human leukocyte antigen antibodies.

    abstract:BACKGROUND:Patients with pretransplantation strong donor-specific anti-human leukocyte antigen (HLA) antibodies (DSA) are at higher risk for rejection. We aimed to study the safety of kidney transplantation in patients with lower strength DSAs in a prospective cohort study. METHODS:Three hundred and seventy-three cons...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000000191

    authors: Marfo K,Ajaimy M,Colovai A,Kayler L,Greenstein S,Lubetzky M,Gupta A,Kamal L,de Boccardo G,Masiakos P,Kinkhabwala M,Akalin E

    更新日期:2014-11-27 00:00:00

  • The large center variation in half-lives of kidney transplants.

    abstract::Based on a log-linear model for analyzing multiple effects, center variation in the UCLA Transplant Registry is the most influential factor in early renal graft survival. Among 68 active centers accounting for 70% of all transplants between 1985 and 1989, the 1-year graft survival (adjusted for 15 covariates) varied f...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199202010-00018

    authors: Gjertson DW,Terasaki PI

    更新日期:1992-02-01 00:00:00

  • Incidence and risk factors of glucose metabolism disorders in kidney transplant recipients: role of systematic screening by oral glucose tolerance test.

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    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e31820f0877

    authors: Caillard S,Eprinchard L,Perrin P,Braun L,Heibel F,Moreau F,Kessler L,Moulin B

    更新日期:2011-04-15 00:00:00

  • Corynebacterium liquefaciens-induced suppressor T cells in graft-versus-host reaction.

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    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-198001000-00009

    authors: Kobayashi M,Kawashima K,Yamada K

    更新日期:1980-01-01 00:00:00

  • Are indoleamine-2,3-dioxygenase producing human dendritic cells a tool for suppression of allogeneic T-cell responses?

    abstract:BACKGROUND:Suppressive dendritic cells (DCs) are a promising tool for tolerance induction in transplantation. A human DCs subpopulation, which constitutively expresses indoleamine-2,3-dioxygenase (IDO), a molecule shown to prevent the rejection of fetus during pregnancy, has recently been described. This subset, charac...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.tp.0000251646.09702.ec

    authors: Löb S,Ebner S,Wagner S,Weinreich J,Schäfer R,Königsrainer A

    更新日期:2007-02-27 00:00:00

  • Intragraft cytokine profile during human liver allograft rejection.

    abstract::Forty-three human liver allograft biopsies and normal liver were directly analyzed for inflammatory and immunoregulatory cytokine gene expression by polymerase chain reaction (PCR). IL-5 gene expression was predominantly present in biopsies from liver allografts with histopathological evidence of acute rejection. IL-2...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199202010-00035

    authors: Martinez OM,Krams SM,Sterneck M,Villanueva JC,Falco DA,Ferrell LD,Lake J,Roberts JP,Ascher NL

    更新日期:1992-02-01 00:00:00

  • Donor factors influencing graft outcomes in live donor kidney transplantation.

    abstract::Living donor renal allograft survival is superior to that achieved from deceased donors, although graft outcome is suboptimal in some of these patients. In an effort to identify the subset of patients at high risk for poor outcomes we studied donor risk factors in 248 living kidney donor-recipient pairs. Unadjusted do...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.tp.0000256284.78721.ba

    authors: Issa N,Stephany B,Fatica R,Nurko S,Krishnamurthi V,Goldfarb DA,Braun WE,Dennis VW,Heeger PS,Poggio ED

    更新日期:2007-03-15 00:00:00

  • The risks, benefits, and costs of expanding donor criteria. A collaborative prospective three-year study.

    abstract::The study purpose was to identify risks, benefits and costs associated with an expanded donor protocol. The protocol design evaluated organs rescued using expanded donor criteria and weighed all costs associated with doing so. Costs were measured against conditions experienced with expanded and traditional criteria an...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199560120-00021

    authors: Jacobbi LM,McBride VA,Etheredge EE,McDonald JC,Cooper ES,Frey D,Boudreaux JP,Gonzalez F,Van Meter C,McMillan R

    更新日期:1995-12-27 00:00:00

  • CD4+CD45RO+CD25-/lowCD127+: CD4+CD45RO+CD25hiCD127-/low Ratio in Peripheral Blood: A Useful Biomarker to Detect Cardiac Allograft Vasculopathy in Heart Transplanted Patients.

    abstract:BACKGROUND:Cardiac allograft vasculopathy (CAV) is a major limitation in long-term graft survival after heart transplantation (HTx). Its prediction and detection at an early stage is a challenge because an accurate, minimally invasive blood test is lacking. The aim of this study was to analyze the relationship of Tact ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000000493

    authors: Roldán C,Mirabet S,Cecilia C,Brossa V,Roig E,Martín C,Gelpí C

    更新日期:2015-07-01 00:00:00

  • How deceased donor transplantation is impacting a decline in commercial transplantation-the Tamil Nadu experience.

    abstract::India with a population of 1.2 billion has a renal transplantation rate of 3.25 per million population. The major cause of chronic kidney disease is hypertension and diabetes. The crude and age-adjusted incidence rates of end-stage renal disease are estimated to be 151 and 232 per million population, respectively, in ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e3182469b91

    authors: Abraham G,Reddy YN,Amalorpavanathan J,Daniel D,Roy-Chaudhury P,Shroff S,Reddy Y

    更新日期:2012-04-27 00:00:00

  • The lymphatic drainage of the rat prostate and its status as an immunologically privileged site.

    abstract::Recent suggestions that the rat prostate is an alymphatic, immunologically privileged site stimulated further investigation of its status using a variety of techniques. Fixation of certain organs by vascular perfusion of glutaraldehyde followed by plastic embedding avoids the distortion and stromal reorganization that...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-197902000-00011

    authors: Neaves WB,Billingham RE

    更新日期:1979-02-01 00:00:00

  • CD4 lymphocytopenia as a risk factor for skin cancers in renal transplant recipients.

    abstract:BACKGROUND:Renal transplant recipients are at increased risk of developing skin cancer. It remains difficult to establish the actual influence of overimmunosuppression in the development of skin cancers. We investigated whether lymphocyte subset count may predict the risk of developing skin cancer in long-term renal tr...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199805150-00022

    authors: Ducloux D,Carron PL,Rebibou JM,Aubin F,Fournier V,Bresson-Vautrin C,Blanc D,Humbert P,Chalopin JM

    更新日期:1998-05-15 00:00:00

  • Factors influencing T-lymphopoiesis after allogeneic hematopoietic cell transplantation.

    abstract::In adult recipients of allogeneic hematopoietic cell transplants (HCT) studied at 1 year after grafting, there was a significant correlation between the counts of T cell receptor excision circle (TREC)-containing CD4 T cells (presumed recent thymic emigrants) and the counts of total T cells (r=0.65, P<0.001). Thus, th...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-200204150-00026

    authors: Storek J,Joseph A,Dawson MA,Douek DC,Storer B,Maloney DG

    更新日期:2002-04-15 00:00:00

  • Alloantibodies against donor epidermis and early kidney transplant rejection.

    abstract::We have previously observed that transplant recipient sera with endothelial antibodies are bound to epidermal cells, as shown by immunofluorescence on sections of skin. It was also reported that early kidney failures that occurred despite negative T cell crossmatches were associated with, and could have been predicted...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199102000-00019

    authors: Moraes JR,Moraes ME,Luo YM,Stastny P

    更新日期:1991-02-01 00:00:00

  • Retinal complications in patients with solid organ or bone marrow transplantations.

    abstract:BACKGROUND:The administration of systemic immunosuppressive agents to recipients of solid organ or bone marrow transplants results in an immunocompromised status. As the number of organ recipients and their life span increase with recent progress in organ transplantation, ocular complications tend to become more divers...

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    pub_type: 杂志文章

    doi:10.1097/01.tp.0000259386.59375.8a

    authors: Chung H,Kim KH,Kim JG,Lee SY,Yoon YH

    更新日期:2007-03-27 00:00:00

  • Prevention of acute allograft rejection in nonhuman primate lung transplant recipients: induction with chimeric anti-interleukin-2 receptor monoclonal antibody improves the tolerability and potentiates the immunosuppressive activity of a regimen using low

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    pub_type: 杂志文章

    doi:10.1097/00007890-200002270-00005

    authors: Hausen B,Gummert J,Berry GJ,Christians U,Serkova N,Ikonen T,Hook L,Legay F,Schuler W,Schreier MH,Morris RE

    更新日期:2000-02-27 00:00:00

  • Prevalence and risk factors of noncontrolled and resistant arterial hypertension in renal transplant recipients.

    abstract:BACKGROUND:Arterial hypertension (HT) is common in renal transplant recipients (RTRs). Control of HT is not optimal in this high-risk population despite recommendations for target blood pressure levels under 130/80 mm Hg. METHODS:We performed a cross-sectional analysis of the prevalence of uncontrolled HT, and using a...

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    pub_type: 杂志文章

    doi:10.1097/TP.0000000000000467

    authors: Vetromile F,Pernin V,Szwarc I,Garrigue V,Delmas S,Mourad G,Fesler P

    更新日期:2015-05-01 00:00:00

  • Liver transplantation using an organ donor with HELLP syndrome.

    abstract:BACKGROUND:The shortage of organs for liver transplantation has forced transplant centers to expand the donor pool by using donors traditionally labeled as marginal. One such example is liver transplantation using a donor with HELLP syndrome (hemolysis, elevated liver enzymes, and low platelets), a disorder of late pre...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.TP.0000101510.01404.F0

    authors: Briceno PJ,Ortiz JA,Manzarbeitia C,Jeon H,Munoz SJ,Rothstein KD,Araya V,Gala I,Reich DJ

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  • Human heart endothelial-cell-restricted allorecognition.

    abstract::We studied the reactivity of cardiac graft-infiltrating cells, cultured from endomyocardial biopsy specimens, toward heart endothelial cells (Hec). In two cases, Hec derived from the specific donor heart or Hec compatible with the donor were lysed, but not the syngeneic B cell line. A vessel-derived endothelial cell l...

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    pub_type: 杂志文章

    doi:10.1097/00007890-199608150-00017

    authors: Jutte NH,Knoop CJ,Heijse P,Balk AH,Mochtar B,Claas FH,Weimar W

    更新日期:1996-08-15 00:00:00

  • A quantitative survey of Western Muslim attitudes to solid organ donation.

    abstract:BACKGROUND:It is imperative for healthcare providers to examine Western Muslim attitudes on organ donation, because they are reluctant donors. We explored such opinion with the aid of a quantitative survey. METHODS:Voluntary completion of an anonymous survey was promoted (online and paper sampling). For a population t...

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    pub_type: 杂志文章

    doi:10.1097/TP.0b013e318231ea17

    authors: Sharif A,Jawad H,Nightingale P,Hodson J,Lipkin G,Cockwell P,Ball S,Borrows R

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  • Liver transplantation restores endocrine cells in patients with familial amyloidotic polyneuropathy.

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    doi:10.1097/00007890-200009150-00015

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  • The vanishing importance of age in renal transplantation.

    abstract:BACKGROUND:The growing number of patients awaiting a kidney transplant raises questions about allocation of kidneys to the elderly and about the use of elderly donors. In all reported studies analyzing the influence of age on the outcome after renal transplantation, age is investigated as a categorical variable. METHO...

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    pub_type: 杂志文章

    doi:10.1097/00007890-199902270-00015

    authors: Roodnat JI,Zietse R,Mulder PG,Rischen-Vos J,van Gelder T,IJzermans JN,Weimar W

    更新日期:1999-02-27 00:00:00

  • Natural killer cell interaction with murine allogeneic MHC class I molecules.

    abstract::Class I molecules of the MHC affect target cell sensitivity to NK cell repertoire. In the mouse, absence of MHC class I molecules on target cells is associated with an increased susceptibility to NK cell-mediated lysis, while syngeneic class I molecules confer protection. In contrast to the protective role of syngenei...

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    pub_type: 杂志文章

    doi:10.1097/00007890-199508000-00013

    authors: Salcedo M,Höglund P,Ljunggren HG

    更新日期:1995-08-15 00:00:00

  • In vivo treatment with antiporcine T cell antibodies.

    abstract::The effects of in vivo administration of monoclonal antibodies directed against the two major mature T cell subsets of miniature swine have been examined. Antibody 76-2-11, specific for the porcine CD8 cell-surface antigen, caused elimination of CD8+ T cells from the peripheral lymphocyte pool by 4-6 days following a ...

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    pub_type: 杂志文章

    doi:10.1097/00007890-199007000-00014

    authors: Suzuki T,Sundt TM 3rd,Mixon A,Sachs DH

    更新日期:1990-07-01 00:00:00