Retinal complications in patients with solid organ or bone marrow transplantations.

abstract：:Renal allograft recipients treated with cyclosporine (CsA) have increased renal vascular resistance that falls when CsA is stopped. With the aim of identifying whether CsA-treated patients with excellent renal function also have an alteration in renal vascular tone and to investigate which vessels are affected, we hav...

journal_title：Transplantation

authors： Cairns HS,Raval U,Neild GH

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:While previous surveys have demonstrated the psychological impact on living-related liver transplantation (LRLT) donors, such as anxiety, depression, ambivalence and anger, the details regarding the relevant factors that affect donors' psychological status have not been well described. METHODS:To evaluate e...

journal_title：Transplantation

authors： Hayashi A,Noma S,Uehara M,Kuwabara H,Tanaka S,Furuno Y,Hayashi T

更新日期：2007-11-27 00:00:00

abstract：:Most patients with secondary hypertension due to renal disease or on maintenance hemodialysis have lost the physiologic fall of blood pressure during sleep. To test the notion that kidney transplantation normalizes the blood pressure profile, we monitored ambulatory blood pressure over 24 hr in 45 patients (29 males a...

journal_title：Transplantation

authors： Gatzka CD,Schobel HP,Klingbeil AU,Neumayer HH,Schmieder RE

更新日期：1995-05-15 00:00:00

abstract：:Suspensions of viable lymph node cells (LNCs), both unlabeled and 3H-uridine labeled, from adult Fischer (FI) rats were inoculated into the lumens of established, surgically isolated segments of ileum in adult (FI x DA)F1 hybrid hosts. Vascular, lymphatic, and nerve supplies of the isolated segment were preserved. It ...

journal_title：Transplantation

authors： Seelig LL Jr,Billingham RE

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:Better preservation strategies for the storage of donation after circulatory death grafts are essential to improve graft function and to increase the kidney donor pool. We compared continuous normothermic ex vivo kidney perfusion (NEVKP) with hypothermic anoxic machine perfusion (HAMP) and static cold storag...

journal_title：Transplantation

authors： Urbanellis P,Hamar M,Kaths JM,Kollmann D,Linares I,Mazilescu L,Ganesh S,Wiebe A,Yip PM,John R,Konvalinka A,Mucsi I,Ghanekar A,Bagli DJ,Robinson LA,Selzner M

更新日期：2020-05-01 00:00:00

abstract：:Consecutive patients transplanted between January 1984 and December 1988 were followed until August 1992 to detect fatal and nonfatal thromboembolic complications, including sudden death, acute and chronic myocardial infarction, pulmonary and peripheral embolisms, stroke, and thrombophlebitis. The probability of devel...

journal_title：Transplantation

authors： Forrat R,Ferrera R,Boissonnat P,Adeleine P,Dureau G,Ninet J,De Lorgeril M

更新日期：1996-03-15 00:00:00

abstract：:In a prospective longitudinal study, detection of cytomegalovirus (CMV) DNA in plasma (plasma polymerase chain reaction [PCR]) was compared with PCR of CMV DNA in peripheral blood leukocytes (PBL PCR), the CMV pp65 antigenemia assay, and viral cultures from blood, urine, and throat of 29 patients, 14 of whom received ...

journal_title：Transplantation

authors： Boeckh M,Gallez-Hawkins GM,Myerson D,Zaia JA,Bowden RA

更新日期：1997-07-15 00:00:00

abstract：:A single posttransplant test for human leukocyte antigen (HLA) antibodies in heart and lung graft patients was examined for its predictive value for graft survival as part of the 13th and 14th international histocompatibility workshops. We included patients with HLA antibodies who were tested 6 or more months after tr...

journal_title：Transplantation

authors： Morales-Buenrostro LE,Castro R,Terasaki PI

更新日期：2008-02-15 00:00:00

abstract：:Conjugation of dextran-coated superparamagnetic iron oxide (SPIO) particles with transactivator protein (Tat)-peptide and fluorescein isothiocyanate (FITC) allows cells to readily uptake SPIO particles. This makes possible high-resolution, real-time imaging of these cells by magnetic resonance imaging (MRI). First, we...

journal_title：Transplantation

authors： Kaufman CL,Williams M,Ryle LM,Smith TL,Tanner M,Ho C

更新日期：2003-10-15 00:00:00

abstract：:In organ transplantation, blood borne cells and macromolecules (e.g., antibodies) of the host immune system are brought into direct contact with the endothelial cell lining of graft vessels. In this location, graft endothelial cells play several roles in allograft rejection, including the initiation of rejection respo...

journal_title：Transplantation

authors： Al-Lamki RS,Bradley JR,Pober JS

更新日期：2008-11-27 00:00:00

abstract：BACKGROUND:Mycophenolate mofetil (MMF) therapy compared with azathioprine has not led to improved long-term renal allograft outcomes perhaps as MMF dose is limited by tolerability and dose reduction is associated with inferior graft outcome. The consequences, however, of dose reduction of mycophenolate mofetil relative...

journal_title：Transplantation

authors： Shah S,Collett D,Johnson R,Raftery M,Rudge C,Yaqoob MM

更新日期：2008-10-27 00:00:00

abstract：INTRODUCTION:We investigated the putative candidate biomarkers of graft rejection in peripheral blood of intestinal transplant patients. MATERIALS AND METHODS:Peripheral blood gene expression analysis was performed in intestinal transplant patients. The results were matched with concurrent graft biopsies using bioinfo...

journal_title：Transplantation

authors： Andreev VP,Tryphonopoulos P,Blomberg BB,Tsinoremas N,Weppler D,Neuman DR,Volsky A,Nishida S,Tekin A,Selvaggi G,Levi DM,Tzakis AG,Ruiz P

更新日期：2011-12-27 00:00:00

abstract：BACKGROUND:Increased numbers of macrophages and myofibroblasts are observed to occur in chronic renal allograft rejection (CR). The aim of this study was to examine the expression of cellular markers for the macrophage and myofibroblast in early renal transplant biopsy specimens and correlate these findings with allogr...

journal_title：Transplantation

authors： Pilmore HL,Painter DM,Bishop GA,McCaughan GW,Eris JM

更新日期：2000-06-27 00:00:00

abstract：BACKGROUND:BK polyomavirus infection has been reported in 10% to 60% of renal transplant recipients with progression to BK nephropathy (BKN) occurring in 1% to 5% of patients. Graft loss occurs in up to 60% of renal transplant recipients with BKN. Because BK polyomavirus infection is believed, in part, to be a manifest...

journal_title：Transplantation

authors： Guasch A,Roy-Chaudhury P,Woodle ES,Fitzsimmons W,Holman J,First MR,FK778 BK Nephropathy Study Group.

更新日期：2010-10-27 00:00:00

abstract：BACKGROUND:Individuals undergoing therapeutic immunosuppression are at risk of severe varicella-zoster virus (VZV) infection, particularly those without evidence of previous infection. METHODS:Eleven children, median age 10 months (range 5.5 months to 7 years and 9 months) received one dose of varicella vaccine (Varil...

journal_title：Transplantation

authors： Donati M,Zuckerman M,Dhawan A,Hadzic N,Heaton N,North-Lewis P,Mieli-Vergani G

更新日期：2000-11-15 00:00:00

abstract：BACKGROUND:Chronically elevated vasopressin (VP) plasma levels have been shown to induce accelerated renal function decline in rats with chronic renal failure. Whether endogenous VP is a renal risk factor in humans has not been investigated yet. We aimed to investigate whether, in renal transplant recipients, VP concen...

journal_title：Transplantation

authors： Meijer E,Bakker SJ,de Jong PE,Homan van der Heide JJ,van Son WJ,Struck J,Lems SP,Gansevoort RT

更新日期：2009-08-27 00:00:00

abstract：:Modified limiting dilution analysis (LDA) techniques were used to evaluate the mobilization of antigen-stimulated helper T lymphocytes (HTL) and cytotoxic T lymphocytes (CTL) following allogeneic heterotopic cardiac transplantation. These modified LDA techniques allow a quantitative comparison of T cells that have bee...

journal_title：Transplantation

authors： Bishop DK,Shelby J,Eichwald EJ

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:In the present study we examined the effect of the timing of marrow infusion on engraftment in nonmyeloablatively conditioned mice. METHODS:B10 mice were conditioned with decreasing doses of total body irradiation (TBI) and reconstituted with bone marrow cells (BMCs) from major histocompatibility complex-di...

journal_title：Transplantation

authors： Xu H,Exner BG,Chilton PM,Tanner MK,Mueller YM,Rezzoug F,Ildstad ST

更新日期：2004-03-27 00:00:00

abstract：:We have previously demonstrated that the placental spongiotrophoblast and yolk sac venous plexus express paternally derived H-2K and D (class I) antigens in a manner accessible to maternal circulation, and that the placenta serves to prevent antipaternal antibodies from reaching the fetus. Kinetic studies indicated th...

journal_title：Transplantation

authors： Raghupathy R,Singh B,Wegmann TG

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:The first generic tacrolimus product gained Food and Drug Administration approval in August 2009. This prospective, observational trial sought to determine the need for dose titrations and measure drug cost savings on conversion to generic tacrolimus. METHODS:Transplant recipients on stable tacrolimus doses...

journal_title：Transplantation

authors： McDevitt-Potter LM,Sadaka B,Tichy EM,Rogers CC,Gabardi S

更新日期：2011-09-27 00:00:00

abstract：:Although bisphosponates are proposed as first-line treatment for posttransplant bone disease they are not optimal in all situations. A kidney transplant recipient developed hypercalcemia from mobilization of extraskeletal calcium. He had low serum parathyroid hormone and vitamin D; high calcium excretion; and normal c...

journal_title：Transplantation

authors： Dhingra RK,Sprague SM,Ojo AO,Leavey SF

更新日期：2001-06-27 00:00:00

abstract：BACKGROUND:The aim of this study was to analyze humoral xenoreactivity of various Old World primate species sera against pig islets and the effects of these sera on pig islet viability and function after culture. METHODS:Freshly isolated or cultured adult pig islets were analyzed by immunohistology or by cytofluorimet...

journal_title：Transplantation

authors： Mirenda V,Le Mauff B,Boeffard F,Cassard A,Jugeau N,Soulillou JP,Anegon I

更新日期：1998-12-15 00:00:00

abstract：:Vascularized xenografts are rejected acutely and hyperacutely in concordant or discordant combinations, respectively. We investigated the impact of the donor-recipient combination on the rejection of arterial xenografts, analyzing the cellular and extracellular matricial compartments. Aortic xenografts were performed ...

journal_title：Transplantation

authors： Allaire E,Mandet C,Bruneval P,Bensenane S,Becquemin JP,Michel JB

更新日期：1996-09-27 00:00:00

abstract：BACKGROUND:We examined whether oral administration of alloantigen could induce the prolonged survival of cardiac allografts. METHODS:Hearts from CBK (H2k+Kb) transgenic or (C57BL/10xCBA)F1 (H2bxH2k) mice were transplanted into CBA (H2k) recipients pretreated orally with 1 x 10(7) donor splenocytes in the presence or a...

journal_title：Transplantation

authors： Niimi M,Witzke O,Bushell A,Hara M,Morris PJ,Wood KJ

更新日期：2000-11-27 00:00:00

abstract：BACKGROUND:In a randomized, controlled study we investigated the clinical efficacy of the microemulsion formulation of cyclosporine (Neoral) in comparison with Sandimmune (SIM) in the treatment of patients who underwent primary orthotopic liver transplantation (OLT). METHODS:In total, 33 patients were randomized in a ...

journal_title：Transplantation

authors： Graziadei IW,Wiesner RH,Marotta PJ,Porayko MK,Dahlke LJ,Wilson SM,Steers JL,Krom RA

更新日期：1997-09-15 00:00:00

abstract：:Idarubicin was conjugated to anti-Ly-2.1 and anti-L3T4 monoclonal antibodies. These conjugates were used to investigate their effects on skin graft survival in mice. Several donor and recipient combinations were used so that the effect of individual or mixtures of conjugates on class I and class II antigenic differenc...

journal_title：Transplantation

authors： Smyth MJ,McKenzie IF,Pietersz GA

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Recent changes in policies guiding allocation of transplant kidneys are predicted to increase sharing between distant geographic regions. The potential exists for an increase in cold ischemia time (CIT) with resulting increases in delayed graft function (DGF) and transplant-related costs (TRC). We sought to ...

journal_title：Transplantation

authors： Serrano OK,Vock DM,Chinnakotla S,Dunn TB,Kandaswamy R,Pruett TL,Feldman R,Matas AJ,Finger EB

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Specific tolerance after combined kidney and bone marrow transplantation for multiple myeloma with end-stage renal disease through mixed lymphohematopoietic chimerism has been achieved, as evidenced by prolonged normal renal function without ongoing immunosuppression. METHODS:To achieve potent antimyeloma r...

journal_title：Transplantation

authors： Spitzer TR,Sykes M,Tolkoff-Rubin N,Kawai T,McAfee SL,Dey BR,Ballen K,Delmonico F,Saidman S,Sachs DH,Cosimi AB

更新日期：2011-03-27 00:00:00

abstract：:Teratoma 402 AX is an embryo-like tumor cell line originally derived from the testicles of strain 129/J mice. This teratocarcinoma grows well in males and pregnant females but poorly in virgin females when given in small doses. Induction of growth of this tumor is syngeneic and allogeneic virgin females was achieved b...

journal_title：Transplantation

authors： Isa AM,Sanders BR

更新日期：1975-10-01 00:00:00

abstract：:Chronic graft-versus-host disease often results in a combined deficiency of humoral and cell-mediated immunity. Clinical and experimental studies have suggested that the decrease in B cell responsiveness is due to a failure of B cell production in the bone marrow, intrinsic B cell defects, excessive suppressor T cell ...

journal_title：Transplantation

authors： Schreiber KL,Forman J

更新日期：1993-03-01 00:00:00