Abstract:
:Teratoma 402 AX is an embryo-like tumor cell line originally derived from the testicles of strain 129/J mice. This teratocarcinoma grows well in males and pregnant females but poorly in virgin females when given in small doses. Induction of growth of this tumor is syngeneic and allogeneic virgin females was achieved by modification of macrophage function by antimacrophage serum. Tumor-bearing animals of both sexes, whether treated with antimacrophage serum or normal rabbit serum, produce antitumor antibodies of the IgM, IgA, IgG, IgG, and IgG classes. These antibodies are bound to the tumor cell surface and are not cytotoxic to the target cell in the presence of rabbit or guinea pig complement.
journal_name
Transplantationjournal_title
Transplantationauthors
Isa AM,Sanders BRdoi
10.1097/00007890-197510000-00005subject
Has Abstractpub_date
1975-10-01 00:00:00pages
296-302issue
4eissn
0041-1337issn
1534-6080journal_volume
20pub_type
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