Abstract:
:The present study was carried out to investigate the effects of rboIL-1 beta, rboIL-2, and rboIFN-gamma on food intake and forestomach motility in conscious dwarf goats. The intravenous injection of rboIL-1 beta (1 micrograms kg-1) resulted in tachycardia and an immediate fever that reached peak values 45 and 180 min after injection. At 9 to 13 min after rboIL-1 beta administration, both frequency and amplitude of rumen contractions rapidly diminished, being minimal at 30 min; during the fever, all goats refused to eat. Compared with the fever induced by rboIL-1 beta, that caused by rboIFN-gamma (2 micrograms kg-1 IV) was delayed in onset. Although the biphasic fever after rboIFN-gamma was more pronounced than after rboIL-1 beta, the changes in forestomach motility, food intake, and heart rate were less than after rboIL-1 beta. No changes in rectal temperature, heart rate, forestomach motility, and food intake were observed after rboIL-2 (1 micrograms kg-1 IV) injection. These results strongly indicate that the effects of cytokines on body temperature can be dissociated from their effects on food intake. Furthermore, these data suggest a possible relationship between forestomach motility and food intake.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
van Miert AS,Kaya F,van Duin CTdoi
10.1016/0031-9384(92)90362-6subject
Has Abstractpub_date
1992-11-01 00:00:00pages
859-64issue
5eissn
0031-9384issn
1873-507Xpii
0031-9384(92)90362-6journal_volume
52pub_type
杂志文章abstract::Vitamin D has been shown in a wide variety of species to play critical roles in neurodevelopment. Vitamin D deficiency disrupts development of the brain and can cause lasting behavioral dysfunction. Zebrafish have become an important model for the study of development in general and neurodevelopment in particular. Zeb...
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journal_title:Physiology & behavior
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pub_type: 杂志文章
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