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Kidney transplantation from marginal donors.

Abstract：

AIM:The increasing demand for transplantation and the shortage of available organs limit the success of organ transplant programs. The use of marginal donors to expand the donor pool is receiving increased attention. We reviewed a 28-month experience of kidney transplants from marginal donors to assess the impact on patient and graft survival. PATIENTS AND METHODS:From January 2001 to May 2003, 78 kidney transplants were performed, including 50 grafts from cadaver donors and 28 from living donors with 3 patients receiving a double kidney transplant. The patients were divided into 4 groups: 31 patients received a kidney from an ideal cadaver donor (group 1a); 19 patients received a graft from a marginal cadaver donor (group 1b); 19 patients received an ideal living related kidney (group 2a); and 9 patients received a marginal living kidney graft (group 2b). RESULTS:Twenty-eight grafts from marginal donors were transplanted with an average follow-up of 16 months (range, 1-28 months). The graft survival rates for groups 1a, 1b, 2a, and 2b were 93%, 79%, 100%, and 100% and patient survival rates were 96%, 89%, 100%, and 100%, respectively. CONCLUSION:Despite the observation that use of marginal donors has been associated with a worse outcome compared with ideal donors, we of such grafts resulted in improved quality of life and survival expectancy compared with maintenance dialysis. The marginal kidney donors represent a feasible way to improve the donor pool.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Veroux P,Puliatti C,Veroux M,Cappello D,Macarone M,Puliatti D,Vizcarra D

doi

10.1016/j.transproceed.2004.02.012

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

497-8

issue

3

eissn

0041-1345

issn

1873-2623

pii

S0041134504001563

journal_volume

36

pub_type

杂志文章

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