Factors related to post-liver transplantation acute renal failure.

Abstract:

:Acute renal failure (ARF) after liver transplantation (OLT) is a common complication with severe impact on early and late prognosis of recipients. Factors predicting its incidence have not been fully identified due to the lack of a universal standard as well as the variance of data between transplant centers. To identify factors related to post-OLT ARF, we retrospectively collected materials on 89 patients, who underwent OLT from 1999 to 2001 in our center. Factors associated with post-OLT ARF were identified using univariate logistic regression. Significant factors were then entered into a multivariate logistic regression to identify factors independently associated with post-OLT ARF. Upon univariate analysis, intraoperative volume of blood transfusion (P = .041) and duration of operation (P = .005) were significant. ARF was associated with a poor prognosis (P < .001). Only duration of operation (P = .026) was an independent factor predicting the development of ARF. In conclusion, intraoperative volume of blood transfusion and duration of operation were factors contributing to post-OLT ARF in which the duration of the operation was an independent risk factor. The incidence of post-OLT ARF greatly increased recipient mortality in the early postoperative period.

journal_name

Transplant Proc

authors

Wei Y,Zhang L,Lin H,Li J,Li B,Yan L,Wen T,Zeng Y,Lu S

doi

10.1016/j.transproceed.2006.08.156

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

2982-4

issue

9

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(06)01096-7

journal_volume

38

pub_type

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