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Liver transplantation from maastricht category 2 non-heart-beating donors: a source to increase the donor pool?

Abstract：

INTRODUCTION:The demand for liver transplantation has increasingly exceeded the supply of cadaver donor organs. Non-heart-beating donors (NHBDs) may be an alternative to increase the cadaver donor pool. The outcome of 20 liver transplants from Maastricht category 2 NHBD was compared with that of 40 liver transplants from heart-beating donors (HBDs). After unsuccessful cardiopulmonary resuscitation (CPR), cardiopulmonary support with simultaneous application of chest and abdominal compression (CPS; n = 6) or cardiopulmonary bypass (CPB; n = 14) was used to maintain the donors. RESULTS:At a minimum follow-up of 2 years, actuarial patient and graft survival rates with livers from Maastricht category 2 NHBD were 80% and 55%, respectively. Transplantation of organs from these donors was associated with a significantly higher incidence of primary nonfunction, biliary complications, and more severe initial liver dysfunction compared with organs from HBDs. The graft survival rates was 83% for livers from NHBDs preserved with CPS and 42% in those maintained with CPB.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Otero A,Gómez-Gutiérrez M,Suárez F,Arnal F,Fernández-García A,Aguirrezabalaga J,García-Buitrón J,Alvarez J,Máñez R

doi

10.1016/j.transproceed.2004.03.027

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

747-50

issue

3

eissn

0041-1345

issn

1873-2623

pii

S0041134504002866

journal_volume

36

pub_type

杂志文章

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