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Donor intracranial bleeding is associated with advanced transplant coronary vasculopathy: evidence from intravascular ultrasound.

Abstract：

OBJECTIVES:We evaluated the impact of spontaneous intracranial bleeding (ICB) in the donor on transplant coronary vasculopathy using serial intravascular ultrasound examinations. MATERIALS AND METHODS:Between January 1995 and December 2000, 72 recipients underwent cardiac transplantation from donors who had experienced spontaneous ICB (ICB group). Their findings using serial intravascular ultrasound analysis at baseline (within 1 month) and 1 year after transplantation were compared with 90 recipients who had undergone transplantation from trauma donors (trauma group). RESULTS:Compared with the Trauma group, the ICB group showed increased coronary intimal thickness (0.55 +/- 0.33 vs 0.39 +/- 0.3 mm; P = .034), plaque volume (3.84 +/- 2.5 vs 2.28 +/- 1.65 mm(3); P = .015) and plaque burden (7.4 vs 2%) at 1 year after transplantation. CONCLUSIONS:Donor spontaneous ICB is associated with significantly increased coronary vasculopathy.

journal_name

Transplant Proc

journal_title

Transplantation proceedings

authors

Yamani MH,Erinc K,Starling RC,Young JB,Ratliff NB,Cook DJ,Crowe T,Hobbs R,Rincon G,Bott-Silverman C,Bennett R,Smedira N,Tuzcu EM

doi

10.1016/j.transproceed.2004.11.069

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

2564-6

issue

9

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(04)01349-1

journal_volume

36

pub_type

杂志文章

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