Elevated tacrolimus levels associated with intravenous azithromycin and ceftriaxone: a case report.

Abstract:

:Drug interactions are a common occurrence with calcineurin inhibitors. We describe the case of a heart transplant recipient who developed increased tacrolimus blood levels after the administration of intravenous azithromycin and ceftriaxone. Tacrolimus levels decreased after the discontinuation of ceftriaxone and switch from intravenous to oral azithromycin. Transplant recipients who receive intravenous azithromycin and/or ceftriaxone concomitantly with tacrolimus therapy should be monitored closely for the duration of the antibiotic administration.

journal_name

Transplant Proc

authors

Shullo MA,Schonder K,Teuteberg JJ

doi

10.1016/j.transproceed.2010.02.095

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

1870-2

issue

5

eissn

0041-1345

issn

1873-2623

pii

S0041-1345(10)00589-0

journal_volume

42

pub_type

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