Resting energy expenditure in infants with cystic fibrosis.

Abstract:

:To evaluate the contribution of energy expenditure to the energy imbalance seen in cystic fibrosis patients, resting energy expenditure was measured using open-circuit indirect calorimetry in eight infants with cystic fibrosis, aged 2-7 months (mean, 4), without overt lung disease and in 10 healthy age-matched controls. In both groups, we found close, significant, linear correlations between resting energy expenditure and body weight and between resting energy expenditure and fat-free mass as measured by anthropometry. Cystic fibrosis patients had a 26% increase in resting energy expenditure per kilogram of fat-free mass as compared with controls and a 32% increase in resting energy expenditure as compared with predicted values for fat-free mass. These data from young infants free of clinical symptoms suggest a constitutional metabolic disorder in cystic fibrosis and support the need for early nutritional therapy in cystic fibrosis patients.

authors

Girardet JP,Tounian P,Sardet A,Veinberg F,Grimfeld A,Tournier G,Fontaine JL

doi

10.1097/00005176-199402000-00015

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

214-9

issue

2

eissn

0277-2116

issn

1536-4801

journal_volume

18

pub_type

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