Abstract:
:BOLD-contrast functional magnetic resonance imaging (MRI) was used to assess the evolution of tumor oxygenation and blood flow after administration of four different anesthetics: pentobarbital (60 mg/kg), ketamine/xylazine (80/8 mg/kg), fentanyl/droperidol (0.078/3.9 mg/kg), and isoflurane (1.5%). Gradient echo sequences were carried out at 4.7 Tesla in a TLT tumor model implanted in the muscle of NMRI mice. In parallel experiments, tumor blood flow and tumor pO2 were measured using the OxyLite/OxyFlo probe system. A comparison was made with the changes occurring in the skeletal muscle (host tissue). The signal intensity was dramatically decreased in tumors after administration of anesthetics, except isoflurane. These results correlated well with measurements of oxygenation and blood perfusion. Isoflurane produced constant muscle pO2 and blood perfusion although large transient fluctuations in pO2 and blood flow were reported in some tumors. Our results emphasize the need for careful monitoring of the effects of anesthesia when trying to identify new therapeutic approaches that are aimed at modulating tumor hemodynamics.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Baudelet C,Gallez Bdoi
10.1016/j.mri.2004.02.005subject
Has Abstractpub_date
2004-09-01 00:00:00pages
905-12issue
7eissn
0730-725Xissn
1873-5894pii
S0730725X04001213journal_volume
22pub_type
杂志文章abstract::Non-invasive assessment of cartilage properties, specifically water content, could prove helpful in the diagnosis of early degenerative joint diseases. Transverse relaxation times T(2) of human articular cartilage (34 cartilage slices of three donors) were measured on a pixel-by-pixel basis in a clinical whole body MR...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(99)00144-7
更新日期:2000-05-01 00:00:00
abstract:PURPOSE:We present three-dimensional adiabatic inversion recovery prepared ultrashort echo time Cones (3D IR-UTE-Cones) imaging of cortical bone in the hip of healthy volunteers using a clinical 3T scanner. METHODS:A 3D IR-UTE-Cones sequence, based on a short pulse excitation followed by a 3D Cones trajectory, with a ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2017.07.012
更新日期:2017-12-01 00:00:00
abstract::Susceptibility differences are common causes for artifacts in magnetic resonance (MR); therefore, it is important to choose phantom materials in a way that these artifacts are kept at a minimum. In this study, a previously proposed MR imaging (MRI) method [Beuf O, Briguet A, Lissac M, Davis R. Magnetic resonance imagi...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2006.07.005
更新日期:2006-11-01 00:00:00
abstract::Recent compressed sensing techniques allow signal acquisition with less sampling than required by the Nyquist-Shannon theorem which reduces the data acquisition time in magnetic resonance imaging (MRI). However, prior knowledge becomes essential to reconstruct detailed features when the sampling rate is exceedingly lo...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.10.009
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:To evaluate the reproducibility of quantitative diffusion measurements obtained with reduced Field of View (rFOV) and Multi-shot EPI (msEPI) acquisitions, using single-shot EPI (ssEPI) as a reference. METHODS:Diffusion phantom experiments, and prostate diffusion-weighted imaging in healthy volunteers and patie...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2018.04.006
更新日期:2018-09-01 00:00:00
abstract::A parametric method is proposed to examine the relationship between neuronal activity, measured with event related potentials (ERPs), and the hemodynamic response, observed with functional magnetic resonance imaging (fMRI), during an auditory oddball paradigm. After verifying that the amplitude of the evoked response ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(02)00496-4
更新日期:2002-05-01 00:00:00
abstract::The subthalamic nucleus (STN) is one of the most common stimulation targets for treating Parkinson's disease using deep brain stimulation (DBS). This procedure requires precise placement of the stimulating electrode. Common practice of DBS implantation utilizes microelectrode recording to locate the sites with the cor...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.02.006
更新日期:2012-06-01 00:00:00
abstract::Resting fluctuations in arterial CO2 (a cerebral vasodilator) are believed to be an important source of low-frequency blood oxygenation level dependent (BOLD) signal fluctuations. In this study we focus on the two commonly used resting-states in functional magnetic resonance imaging experiments, eyes open and eyes clo...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.06.013
更新日期:2013-04-01 00:00:00
abstract::Budd-Chiari syndrome (BCS) is a rare disorder caused by the obstruction of hepatic venous outflow, leading to sinusoidal congestion, ischemic injury to liver cells and portal hypertension. Long-term survival largely depends on whether hepatocellular carcinoma occurs. A recently available liver-specific contrast medium...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2010.10.013
更新日期:2011-05-01 00:00:00
abstract::Use of conjugated equine estrogens (CEE) has been linked to smaller regional brain volumes in women aged ≥65 years; however, it is unknown whether this results in a broad-based characteristic pattern of effects. Structural magnetic resonance imaging was used to assess regional volumes of normal tissue and ischemic les...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.mri.2010.12.001
更新日期:2011-05-01 00:00:00
abstract::The application of MRI-visible paramagnetic tracers to reveal in vivo connectivity can provide important subject-specific information for multisite, multielectrode intracortical recordings in combined behavioral and physiology experiments. To establish the use of such tracers in the nonhuman primate, we recently compa...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2005.12.031
更新日期:2006-05-01 00:00:00
abstract::Percentage of lipid content of 22 adrenal cortex lesions and their water proton longitudinal relaxation time were measured in vitro at 60 MHz. Although water relaxation times obtained on benign and malignant samples overlap each other, measurements of the percentage of lipids performed on the same tissues allow us to ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(87)90123-8
更新日期:1987-01-01 00:00:00
abstract::This paper presents a data-driven method for the reconstruction and visualisation of curvilinear slices from three-dimensional (3D) magnetic resonance (MR) scans of the head. Visualisation of curvilinear slices, rather than standard planar slices, produces symmetrical views of the cortex and allows small abnormalities...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(98)00132-5
更新日期:1998-12-01 00:00:00
abstract:PURPOSE:To evaluate the use of the double-echo steady-state (DESS) sequence for acquiring high-resolution breast images with diffusion and T2 weighting. MATERIALS AND METHODS:Phantom scans were used to verify the T2 and diffusion weighting of the DESS sequence. Image distortion was evaluated in volunteers by comparing...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2013.12.014
更新日期:2014-05-01 00:00:00
abstract::It has previously been observed that during isometric dorsiflexion exercise, the time course of T2-weighted signal intensity (SI) changes is spatially heterogeneous. The purpose of this study was to test the hypothesis that this spatial heterogeneity would increase at higher contraction intensities. Eight subjects per...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2008.01.023
更新日期:2008-10-01 00:00:00
abstract::We propose a novel processing method for reducing shading artifacts in quantitative susceptibility mapping (QSM) for prostate imaging. In the conventional method, calculation errors in the boundary regions between water and fat cause shading artifacts that degrade the image quality for QSM. In the proposed method, wat...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.11.006
更新日期:2020-02-01 00:00:00
abstract::Etched particle tracks produced after heavy ion irradiation of polymer foils are used as model systems to test the performance of NMR in a newly developed ultrahigh magnetic field gradient system. The stimulated NMR echo decay of molecules diffusing in the channels, formulated in terms of the self part of the intermed...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/0730-725x(94)91527-x
更新日期:1994-01-01 00:00:00
abstract::Our purpose was to investigate three-dimensional (3D) gadolinium-enhanced magnetic resonance angiography (Gd-MRA) in the evaluation of renal transplant arteries. Eleven MR angiography examinations were performed in nine renal transplant patients. Gd-MRA, three-dimensional phase contrast (3D-PC) post-gadolinium, and tw...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(96)00348-7
更新日期:1997-01-01 00:00:00
abstract::Recently, we have demonstrated that the fine-digit topography (millimeter sized) previously identified in the primary somatosensory cortex (SI), using electrophysiology and intrinsic signal optical imaging, can also be mapped with submillimeter resolution using blood-oxygenation-level-dependent (BOLD) functional magne...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2007.05.002
更新日期:2007-07-01 00:00:00
abstract::Super paramagnetic iron oxide Fe(3)O(4) nanoparticles prepared via photochemical reaction in pure form were used for inducing hyperthermia to treat subcutaneous Ehrlich carcinoma implanted in female mice. Our results indicate that the mean temperature profiles at the rectum, periphery of the tumor surface and at the c...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2010.08.010
更新日期:2011-02-01 00:00:00
abstract::Fricke-agarose gels have been irradiated with a proton beam. Then samples have been extracted at different depths with respect to the beam penetration distance, corresponding to different irradiation doses. Relaxation times T1 and T2, measured at 17 MHz, appear sensitive to this kind of radiation. In particular, T2 ex...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/s0730-725x(96)00380-3
更新日期:1997-01-01 00:00:00
abstract::Various analogs of NMR and MRI are now technically possible in optics; specifically, high-resolution laser-pulse shaping and complex pulse sequence generation with well-defined phase shifts has been demonstrated. Here we summarize this technology and discuss the potential for these methods to enhance optical functiona...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2003.08.024
更新日期:2003-12-01 00:00:00
abstract::The successful use of magnetic resonance imaging (MRI) of a moldic fossil dicynodont from the Permian aeolian Hopeman Sandstone Formation of Elgin, Scotland, UK, provides paleontologists with a nondestructive technique for examining fossils preserved in this fashion. For large moldic fossils, medical scanners such as ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2003.09.006
更新日期:2004-02-01 00:00:00
abstract::The purpose of this study was to develop a novel intravascular loopless monopole antenna (ILMA) design specifically for imaging of small vessel walls. The ILMA consisted of an unshielded, low-friction guide wire and a tuning/matching box. The material of the guide wire was nitinol and it was coated with polyurethane. ...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2012.06.032
更新日期:2013-01-01 00:00:00
abstract::An understanding of the nucleation and growth mechanism of methane hydrate in porous space is essential for exploitation and application of hydrates, but the mechanism is yet to be clarified. Magnetic resonance imaging (MRI) was employed to visually analyze the spatial and temporal formation behavior of methane hydrat...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.06.005
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:To evaluate the performance of combined integrated slice-by-slice shimming and readout-segmented EPI (irsEPI) for diffusion-weighted MR imaging (DWI) of the neck at 3Tesla. METHODS:This study was approved by the local ethics committee. An anthropometric phantom of the head/neck region incorporating compartment...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2017.05.004
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:To assess the value of semi-automated segmentation applied to diffusion MRI for predicting the therapeutic response of liver metastasis. METHODS:Conventional diffusion weighted magnetic resonance imaging (MRI) was performed using b-values of 0, 150, 300 and 450s/mm(2) at baseline and days 4, 11 and 39 followin...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2015.08.006
更新日期:2015-12-01 00:00:00
abstract::The prevalence of cartilage lesions is much higher in football athletes than in the general population. Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) has been shown to quantify regional variations of glycosaminoglycan (GAG) concentrations which is an indicator of early cartilage degeneration. The goal of this...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2017.01.008
更新日期:2017-06-01 00:00:00
abstract::Multiparametric MRI is a remarkable imaging method for the assessment of patho-physiological processes. In particular, brain tumor characterization has taken advantage of the development of advanced techniques such as Diffusion- (DWI) and Perfusion- (PWI) Weighted Imaging, but a thorough analysis of meningiomas is sti...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2019.12.003
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:The diagnosis and management of mild traumatic brain injury (MTBI) continue to be subjects of debate, with varying opinions regarding the extent to which tissue-based impairments versus the impacts of other stressors cause ongoing disability. Detecting areas of the brain with abnormalities that can explain s...
journal_title:Magnetic resonance imaging
pub_type: 杂志文章
doi:10.1016/j.mri.2011.12.018
更新日期:2012-05-01 00:00:00