Quantitative susceptibility mapping of prostate with separate calculations for water and fat regions for reducing shading artifacts.

Abstract:

:We propose a novel processing method for reducing shading artifacts in quantitative susceptibility mapping (QSM) for prostate imaging. In the conventional method, calculation errors in the boundary regions between water and fat cause shading artifacts that degrade the image quality for QSM. In the proposed method, water and fat regions are separated, and susceptibilities in these two regions are calculated separately and then combined. Susceptibility in the water regions is calculated by using the fat regions as a background susceptibility source to remove shading artifacts. Susceptibility in the fat regions is calculated by using the constraint that shading artifacts in the water regions are suppressed to improve accuracy. In quantitative evaluation of the method with a numerical simulation, calculation errors for the water and fat regions were reduced by 62% and 85%, respectively, compared with the conventional method. In visual evaluation using human prostate imaging, the proposed method also reduced the shading artifacts unlike the conventional method. The proposed method is expected to improve the performance of QSM in diagnosing such diseases as prostate cancer.

journal_name

Magn Reson Imaging

authors

Sato R,Shirai T,Soutome Y,Bito Y,Ochi H

doi

10.1016/j.mri.2019.11.006

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

22-29

eissn

0730-725X

issn

1873-5894

pii

S0730-725X(19)30146-8

journal_volume

66

pub_type

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