Abstract：
:Budd-Chiari syndrome (BCS) is a rare disorder caused by the obstruction of hepatic venous outflow, leading to sinusoidal congestion, ischemic injury to liver cells and portal hypertension. Long-term survival largely depends on whether hepatocellular carcinoma occurs. A recently available liver-specific contrast medium, gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid (Gd-EOB-DTPA), reportedly has high diagnostic capability for detection of malignant liver tumors. However, there has been no report of the sue of Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) for BCS. We present a case of chronic BCS who underwent both gadopentetate dimeglumine (Gd-DTPA) and Gd-EOB-DTPA-enhanced MRI. Hepatic congestion and edema were seen as slightly hypointense areas on Gd-EOB-DTPA-enhanced hepatobiliary-phase images, although these areas were observed as slightly hyperintense on previously obtained Gd-DTPA-enhanced delayed-phase image. Reduced uptake of Gd-EOB-DTPA by hepatocytes in the region of congestion or edema may account for this difference, which should be recognized in image interpretations.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
Kitajima K,Yoshikawa T,Seo Y,Ohno Y,Yano Y,Miki A,Kanda T,Kanata N,Azuma T,Sugimura Kdoi
10.1016/j.mri.2010.10.013subject
Has Abstractpub_date
2011-05-01 00:00:00pages
579-83issue
4eissn
0730-725Xissn
1873-5894pii
S0730-725X(10)00389-9journal_volume
29pub_type
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